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sample_name:"Ribosomal protein L27" AND xref_links:"drugbank" AND author_name:"E"
Release date: Jan. 15, 2025
Resolution: 2.84 Å
EM Method: Single-particle
Fitted PDBs: 8rl2
Q-score: 0.551
Resolution: 2.84 Å
EM Method: Single-particle
Fitted PDBs: 8rl2
Q-score: 0.551
To Be Published
Sample:
- 60s ribosomal protein l21 (18 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l3 (46 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l35 (14 kDa, Protein from Homo sapiens)
- Guanosine-5'-diphosphate (443 Da, Ligand)
- 60s ribosomal protein l35a (12 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l23 (14 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l28 (15 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l39 (6 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l38 (8 kDa, Protein from Homo sapiens)
- Zinc finger protein 593 (15 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l37 (11 kDa, Protein from Homo sapiens)
- Mrna turnover protein 4 homolog (27 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l9 (21 kDa, Protein from Homo sapiens)
- 5s rrna (38 kDa, RNA from Homo sapiens)
- 60s ribosomal protein l36 (12 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l17 (21 kDa, Protein from Homo sapiens)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- 60s ribosomal protein l8 (28 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ul11 (17 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l15 (24 kDa, Protein from Homo sapiens)
- Eukaryotic translation initiation factor 6 (26 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l23a (17 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l19 (23 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l5 (34 kDa, Protein from Homo sapiens)
- Ribosome biogenesis protein nsa2 homolog (30 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l27a (16 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l30 (12 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- 60s ribosomal protein l27 (15 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l13a (23 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l11 (20 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l6 (32 kDa, Protein from Homo sapiens)
- 28s rrna (1 MDa, RNA from Homo sapiens)
- 60s ribosomal protein l14 (23 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l34 (13 kDa, Protein from Homo sapiens)
- Ribosome biogenesis regulatory protein homolog (41 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l4 (47 kDa, Protein from Homo sapiens)
- Nucleolar gtp-binding protein 2 (83 kDa, Protein from Homo sapiens)
- Protein llp homolog (15 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l31 (14 kDa, Protein from Homo sapiens)
- 5.8s rrna (50 kDa, RNA from Homo sapiens)
- 60s ribosomal protein l7a (30 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l22 (14 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein-like 3 (62 kDa, Protein from Homo sapiens)
- Notchless protein homolog 1 (53 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l13 (24 kDa, Protein from Homo sapiens)
- Probable ribosome biogenesis protein rlp24 (19 kDa, Protein from Homo sapiens)
- Human pre-60s - state 5 (Complex from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Gtp-binding protein 4 (74 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l18 (21 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l7 (29 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l18a (20 kDa, Protein from Homo sapiens)
- Ribosome production factor 2 homolog (35 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l26 (17 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l32 (15 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l37a (10 kDa, Protein from Homo sapiens)
Release date: Dec. 4, 2024
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 9f9s
Q-score: 0.54
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 9f9s
Q-score: 0.54
Kim KQ, Li JJ, Nanjaraj Urs AN, Pacheco ME, Lasehinde V, Denk T, Tesina P, Tomomatsu S, Matsuo Y, McDonald E, Beckmann R, Inada T, Green R, Zaher HS
Mol Cell (2024) 84 pp. 4594- [ DOI: doi:10.1016/j.molcel.2024.10.029 Pubmed: 39566505 ]
Sample:
- 60s acidic ribosomal protein p0 (33 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l19-a (21 kDa, Protein from Saccharomyces cerevisiae)
- 40s ribosomal protein s8-a (22 kDa, Protein from Saccharomyces cerevisiae)
- 40s ribosomal protein s10-a (12 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l7-a (27 kDa, Protein from Saccharomyces cerevisiae)
- Uncharacterized protein yel057c (27 kDa, Protein from Saccharomyces cerevisiae)
- Multiprotein-bridging factor 1 (16 kDa, Protein from Saccharomyces cerevisiae)
- 40s ribosomal protein s16-a (15 kDa, Protein from Saccharomyces cerevisiae)
- Potassium ion (39 Da, Ligand)
- 60s ribosomal protein l43-a (10 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l14-a (15 kDa, Protein from Saccharomyces cerevisiae)
- Saccharomyces cerevisiae s288c 25s ribosomal rna (rdn25-1) (1 MDa, RNA from Saccharomyces cerevisiae)
- Trna (24 kDa, RNA from Saccharomyces cerevisiae)
- 40s ribosomal protein s6-a (27 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l31-a (12 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l36-a (11 kDa, Protein from Saccharomyces cerevisiae)
- 40s ribosomal protein s22-a (14 kDa, Protein from Saccharomyces cerevisiae)
- 40s ribosomal protein s28-a (7 kDa, Protein from Saccharomyces cerevisiae)
- Zinc ion (65 Da, Ligand)
- 40s ribosomal protein s27-a (8 kDa, Protein from Saccharomyces cerevisiae)
- 40s ribosomal protein s11-a (17 kDa, Protein from Saccharomyces cerevisiae)
- 40s ribosomal protein s5 (25 kDa, Protein from Saccharomyces cerevisiae)
- Trna p-site, stalled (24 kDa, RNA from Saccharomyces cerevisiae)
- 60s ribosomal protein l35-a (13 kDa, Protein from Saccharomyces cerevisiae)
- Small ribosomal subunit protein us3 (26 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l30 (11 kDa, Protein from Saccharomyces cerevisiae)
- Glutaraldehyde crosslinked trisome fraction after sucrose density gradient centrifugation from yeast in vitro translation (Complex)
- 60s ribosomal protein l23-a (14 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l38 (8 kDa, Protein from Saccharomyces cerevisiae)
- 40s ribosomal protein s12 (15 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l6-a (20 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l2-a (27 kDa, Protein from Saccharomyces cerevisiae)
- Spermidine (145 Da, Ligand)
- 40s ribosomal protein s17-a (15 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l3 (43 kDa, Protein from Saccharomyces cerevisiae)
- 40s ribosomal protein s24-a (15 kDa, Protein from Saccharomyces cerevisiae)
- 40s ribosomal protein s2 (27 kDa, Protein from Saccharomyces cerevisiae)
- 40s ribosomal protein s1-a (28 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l25 (15 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l8-a (28 kDa, Protein from Saccharomyces cerevisiae)
- Saccharomyces cerevisiae s288c 18s ribosomal rna (rdn18-1) with modifications (1 MDa, RNA from Saccharomyces cerevisiae)
- Ubiquitin (17 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l12-a (17 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l15-a (24 kDa, Protein from Saccharomyces cerevisiae)
- Saccharomyces cerevisiae s288c 5s ribosomal rna (38 kDa, RNA from Saccharomyces cerevisiae)
- 60s ribosomal protein l20-a (20 kDa, Protein from Saccharomyces cerevisiae)
- Yeast disome (Complex from Saccharomyces cerevisiae)
- 60s ribosomal protein l33-a (12 kDa, Protein from Saccharomyces cerevisiae)
- Small ribosomal subunit protein es26a (13 kDa, Protein from Saccharomyces cerevisiae)
- Mrna (Complex from Saccharomyces cerevisiae)
- 60s ribosomal protein l32 (14 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l24-a (17 kDa, Protein from Saccharomyces cerevisiae)
- Small ribosomal subunit protein us10 (13 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l42-a (12 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l5 (33 kDa, Protein from Saccharomyces cerevisiae)
- Mrna (12 kDa, RNA from Saccharomyces cerevisiae)
- Small ribosomal subunit protein es21a (9 kDa, Protein from Saccharomyces cerevisiae)
- 40s ribosomal protein s14-b (14 kDa, Protein from Saccharomyces cerevisiae)
- 40s ribosomal protein s9-a (22 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l18-a (20 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l34-a (13 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l28 (16 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l21-a (18 kDa, Protein from Saccharomyces cerevisiae)
- Small ribosomal subunit protein us14a (6 kDa, Protein from Saccharomyces cerevisiae)
- 40s ribosomal protein s25-a (12 kDa, Protein from Saccharomyces cerevisiae)
- Magnesium ion (24 Da, Ligand)
- Trna (24 kDa, RNA from Saccharomyces cerevisiae)
- 40s ribosomal protein s0-a (28 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l10 (25 kDa, Protein from Saccharomyces cerevisiae)
- Saccharomyces cerevisiae s288c 18s ribosomal rna (rdn18-1) (579 kDa, RNA from Saccharomyces cerevisiae)
- 40s ribosomal protein s17-b (15 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l11-a (19 kDa, Protein from Saccharomyces cerevisiae)
- 40s ribosomal protein s15 (16 kDa, Protein from Saccharomyces cerevisiae)
- Small ribosomal subunit protein es28b (7 kDa, Protein from Saccharomyces cerevisiae)
- 40s ribosomal protein s23-a (16 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l13-a (22 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l17-a (20 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l41-a (3 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l4-a (39 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l16-a (22 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l6-b (20 kDa, Protein from Saccharomyces cerevisiae)
- 40s ribosomal protein s14-a (14 kDa, Protein from Saccharomyces cerevisiae)
- 40s ribosomal protein s19-a (15 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l9-a (21 kDa, Protein from Saccharomyces cerevisiae)
- Guanine nucleotide-binding protein subunit beta-like protein (34 kDa, Protein from Saccharomyces cerevisiae)
- 40s ribosomal protein s7-a (21 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l39 (6 kDa, Protein from Saccharomyces cerevisiae)
- Ubiquitin-60s ribosomal protein l40 (14 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l29 (6 kDa, Protein from Saccharomyces cerevisiae)
- 40s ribosomal protein s30-a (7 kDa, Protein from Saccharomyces cerevisiae)
- 40s ribosomal protein s18-a (17 kDa, Protein from Saccharomyces cerevisiae)
- 40s ribosomal protein s4-a (29 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l27-a (15 kDa, Protein from Saccharomyces cerevisiae)
- Saccharomyces cerevisiae s288c 5.8s ribosomal rna (50 kDa, RNA from Saccharomyces cerevisiae)
- 60s ribosomal protein l37-a (9 kDa, Protein from Saccharomyces cerevisiae)
- Sdd1 (Complex from Saccharomyces cerevisiae)
- 40s ribosomal protein s13 (17 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l26-a (14 kDa, Protein from Saccharomyces cerevisiae)
- 60s ribosomal protein l22-a (13 kDa, Protein from Saccharomyces cerevisiae)
human 80S ribosome bound by a SKI2-exosome complex
Release date: Oct. 23, 2024
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 9g8m
Q-score: 0.405
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 9g8m
Q-score: 0.405
Kogel A, Keidel A, Loukeri MJ, Kuhn CC, Langer LM, Schafer IB, Conti E
Nature (2024) 635 pp. 237-242 [ Pubmed: 39385025 DOI: doi:10.1038/s41586-024-08015-6 ]
Sample:
- 40s ribosomal protein s8 (24 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein el6 (32 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s18 (17 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s14 (16 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s3 (26 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s16 (16 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l37 (11 kDa, Protein from Homo sapiens)
- Exosome complex component rrp45 (49 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l17 (21 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l15 (24 kDa, Protein from Homo sapiens)
- Exosome complex component rrp40,exosome complex component mtr3 (39 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s13 (17 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s24 (15 kDa, Protein from Homo sapiens)
- 28s ribosomal rna (1 MDa, RNA from Homo sapiens)
- 60s ribosomal protein l13a (23 kDa, Protein from Homo sapiens)
- 5.8s ribosomal rna (50 kDa, RNA from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- 40s ribosomal protein s25 (13 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l18 (21 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l21 (18 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s15 (17 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s2 (31 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l35 (14 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s21 (9 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l35a (12 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s29 (6 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s27 (9 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s26 (13 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l9 (21 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s3a (30 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l23a (17 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s4, x isoform (29 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s15a (14 kDa, Protein from Homo sapiens)
- Isoform 2 of hbs1-like protein (30 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s23 (15 kDa, Protein from Homo sapiens)
- Dis3-like exonuclease 1 (125 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s20 (13 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l27 (15 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l11 (20 kDa, Protein from Homo sapiens)
- Exosome complex component rrp43 (30 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l34 (13 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l14 (23 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l7a (30 kDa, Protein from Homo sapiens)
- 18s ribosomal rna (602 kDa, RNA from Homo sapiens)
- 5s ribosomal rna (38 kDa, RNA from Homo sapiens)
- 60s ribosomal protein l13 (24 kDa, Protein from Homo sapiens)
- Exosome complex component rrp41 (26 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l32 (15 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l37a (10 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l23 (14 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s7 (22 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s10 (18 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l39 (6 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s6 (28 kDa, Protein from Homo sapiens)
- Human 80s ribosome bound by a ski2-exosome complex (Complex from Homo sapiens)
- 40s ribosomal protein s30 (6 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l36 (12 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s5 (22 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l24 (17 kDa, Protein from Homo sapiens)
- Exosome complex component rrp4 (33 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l36a (12 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ul30 (29 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l19 (23 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l5 (34 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l27a (16 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l30 (12 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- 60s ribosomal protein l4 (47 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s28 (7 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l31 (14 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l22 (14 kDa, Protein from Homo sapiens)
- Ribosomal protein ul16-like (24 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s12 (14 kDa, Protein from Homo sapiens)
- 40s ribosomal protein sa (32 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s11 (18 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l29 (17 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l3 (46 kDa, Protein from Homo sapiens)
- Exosome complex component rrp42 (32 kDa, Protein from Homo sapiens)
- Exosome complex component csl4 (21 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l28 (15 kDa, Protein from Homo sapiens)
- Helicase ski2w (137 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l38 (8 kDa, Protein from Homo sapiens)
- Exosome complex component rrp46 (25 kDa, Protein from Homo sapiens)
- Receptor of activated protein c kinase 1 (35 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s19 (16 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l8 (28 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l41 (3 kDa, Protein from Homo sapiens)
- Crpv-ires rna (78 kDa, RNA from Cricket paralysis virus)
- Ubiquitin (18 kDa, Protein from Homo sapiens)
- Ubiquitin-60s ribosomal protein l40 (14 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l18a (20 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s17 (15 kDa, Protein from Homo sapiens)
- 40s ribosomal protein s9 (22 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l26 (17 kDa, Protein from Homo sapiens)
- Exosome complex component mtr3 (28 kDa, Protein from Homo sapiens)
Mammalian ternary complex of a translating 80S ribosome, NAC and NatA/E
Release date: Aug. 21, 2024
Resolution: 3.01 Å
EM Method: Single-particle
Fitted PDBs: 9f1b
Q-score: 0.475
Resolution: 3.01 Å
EM Method: Single-particle
Fitted PDBs: 9f1b
Q-score: 0.475
Lentzsch AM, Yudin D, Gamerdinger M, Chandrasekar S, Rabl L, Scaiola A, Deuerling E, Ban N, Shan SO
Nature (2024) 633 pp. 718-724 [ Pubmed: 39169182 DOI: doi:10.1038/s41586-024-07846-7 ]
Sample:
- 60s ribosomal protein l39-like (6 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l10 (24 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s7 (47 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s13 (17 kDa, Protein from Oryctolagus cuniculus)
- Small ribosomal subunit protein us9 (19 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l35a (12 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s3a (30 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l32 (15 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l37 (11 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s11 (18 kDa, Protein from Oryctolagus cuniculus)
- Large ribosomal subunit protein el42 (12 kDa, Protein from Oryctolagus cuniculus)
- Large ribosomal subunit protein ul2 (28 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s29 (6 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s4 (29 kDa, Protein from Oryctolagus cuniculus)
- Large ribosomal subunit protein ul13 (23 kDa, Protein from Oryctolagus cuniculus)
- 60s acidic ribosomal protein p0 (34 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l26 (17 kDa, Protein from Oryctolagus cuniculus)
- N-alpha-acetyltransferase 10 (26 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l37a (10 kDa, Protein from Oryctolagus cuniculus)
- Water (18 Da, Ligand)
- N-alpha-acetyltransferase 15, nata auxiliary subunit (106 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l7a (30 kDa, Protein from Oryctolagus cuniculus)
- Large ribosomal subunit protein el13 (24 kDa, Protein from Oryctolagus cuniculus)
- Large ribosomal subunit protein el18 (21 kDa, Protein from Oryctolagus cuniculus)
- Ubiquitin-ribosomal protein el40 fusion protein (14 kDa, Protein from Oryctolagus cuniculus)
- Nascent polypeptide-associated complex subunit alpha (25 kDa, Protein from Homo sapiens)
- Ribosomal_l23en domain-containing protein (17 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l21 (18 kDa, Protein from Oryctolagus cuniculus)
- Mrna (543 Da, RNA from Oryctolagus cuniculus)
- Ribosomal protein l23 (14 kDa, Protein from Oryctolagus cuniculus)
- Zinc ion (65 Da, Ligand)
- 40s ribosomal protein s9 (22 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l19 (23 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l9 (21 kDa, Protein from Oryctolagus cuniculus)
- Unknown atom or ion (145 Da, Ligand)
- Ribosomal protein l3 (46 kDa, Protein from Oryctolagus cuniculus)
- Rabbit ribosome-nascent chain complex (Complex from Oryctolagus cuniculus)
- Human nac heterodimer (Complex from Homo sapiens)
- 40s ribosomal protein s24 (15 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s8 (24 kDa, Protein from Oryctolagus cuniculus)
- S10_plectin domain-containing protein (18 kDa, Protein from Oryctolagus cuniculus)
- Small ribosomal subunit protein us2 (32 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l31 (14 kDa, Protein from Oryctolagus cuniculus)
- Spermine (202 Da, Ligand)
- Nascent chain (2 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l41 (3 kDa, Protein from Oryctolagus cuniculus)
- Large ribosomal subunit protein el34 (13 kDa, Protein from Oryctolagus cuniculus)
- Small ribosomal subunit protein rack1 (35 kDa, Protein from Oryctolagus cuniculus)
- Small ribosomal subunit protein es21 (9 kDa, Protein from Oryctolagus cuniculus)
- Spermidine (145 Da, Ligand)
- 40s ribosomal protein s2 (31 kDa, Protein from Oryctolagus cuniculus)
- Small ribosomal subunit protein us11 (16 kDa, Protein from Oryctolagus cuniculus)
- P-site trna (15 kDa, RNA from Oryctolagus cuniculus)
- 60s ribosomal protein l22 (14 kDa, Protein from Oryctolagus cuniculus)
- Transcription factor btf3 (17 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l30 (12 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s12 (14 kDa, Protein from Oryctolagus cuniculus)
- Glutathione s-transferase class-mu 26 kda isozyme,n-alpha-acetyltransferase 50 (46 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l12 (17 kDa, Protein from Oryctolagus cuniculus)
- Small ribosomal subunit protein us10 (13 kDa, Protein from Oryctolagus cuniculus)
- Large ribosomal subunit protein el20 (20 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein ul30 (29 kDa, Protein from Oryctolagus cuniculus)
- Large ribosomal subunit protein ul4 (46 kDa, Protein from Oryctolagus cuniculus)
- 5.8s rrna (50 kDa, RNA from Oryctolagus cuniculus)
- 40s ribosomal protein es17 (15 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s30 (14 kDa, Protein from Oryctolagus cuniculus)
- Large ribosomal subunit protein ul22 (21 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s25 (13 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l35 (14 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s6 (28 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein s27a (18 kDa, Protein from Oryctolagus cuniculus)
- Magnesium ion (24 Da, Ligand)
- 60s ribosomal protein l6 (33 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l14 (23 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l36 (12 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein s5 (22 kDa, Protein from Oryctolagus cuniculus)
- Inositol hexakisphosphate (660 Da, Ligand)
- 60s ribosomal protein l27a (16 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein s15a (14 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s23 (15 kDa, Protein from Oryctolagus cuniculus)
- Human nata (Complex from Homo sapiens)
- Large ribosomal subunit protein ul18 (34 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l27 (15 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s3 (31 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s19 (16 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l29 (26 kDa, Protein from Oryctolagus cuniculus)
- Ternary complex of a translating ribosome, nac and nata/e (3 MDa, Complex)
- Ribosomal protein l15 (24 kDa, Protein from Oryctolagus cuniculus)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Ribosomal protein l24 (17 kDa, Protein from Oryctolagus cuniculus)
- Small ribosomal subunit protein us13 (17 kDa, Protein from Oryctolagus cuniculus)
- Human nate with a gst tag (Complex from Homo sapiens)
- 60s ribosomal protein l11 (20 kDa, Protein from Oryctolagus cuniculus)
- Small ribosomal subunit protein es26 (13 kDa, Protein from Oryctolagus cuniculus)
- Human nata/e complex (Complex)
- 60s ribosomal protein l38 (8 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein us19 (17 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s28 (7 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s27 (9 kDa, Protein from Oryctolagus cuniculus)
- 28s rrna (1 MDa, RNA from Oryctolagus cuniculus)
- Large ribosomal subunit protein el28 (15 kDa, Protein from Oryctolagus cuniculus)
- 18s rrna (603 kDa, RNA from Oryctolagus cuniculus)
- 5s rrna (38 kDa, RNA from Oryctolagus cuniculus)
Mammalian quaternary complex of a translating 80S ribosome, NAC, MetAP1 and NatA/E
Release date: Aug. 21, 2024
Resolution: 3.78 Å
EM Method: Single-particle
Fitted PDBs: 9f1c
Q-score: 0.371
Resolution: 3.78 Å
EM Method: Single-particle
Fitted PDBs: 9f1c
Q-score: 0.371
Lentzsch AM, Yudin D, Gamerdinger M, Chandrasekar S, Rabl L, Scaiola A, Deuerling E, Ban N, Shan SO
Nature (2024) 633 pp. 718-724 [ Pubmed: 39169182 DOI: doi:10.1038/s41586-024-07846-7 ]
Sample:
- 60s ribosomal protein l39-like (6 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l10 (24 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s7 (47 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s13 (17 kDa, Protein from Oryctolagus cuniculus)
- Small ribosomal subunit protein us9 (19 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l35a (12 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s3a (30 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l32 (15 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l37 (11 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s11 (18 kDa, Protein from Oryctolagus cuniculus)
- Large ribosomal subunit protein el42 (12 kDa, Protein from Oryctolagus cuniculus)
- Large ribosomal subunit protein ul2 (28 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s29 (6 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s4 (29 kDa, Protein from Oryctolagus cuniculus)
- Large ribosomal subunit protein ul13 (23 kDa, Protein from Oryctolagus cuniculus)
- 60s acidic ribosomal protein p0 (34 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l26 (17 kDa, Protein from Oryctolagus cuniculus)
- N-alpha-acetyltransferase 10 (26 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l37a (10 kDa, Protein from Oryctolagus cuniculus)
- Water (18 Da, Ligand)
- N-alpha-acetyltransferase 15, nata auxiliary subunit (106 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l7a (30 kDa, Protein from Oryctolagus cuniculus)
- Large ribosomal subunit protein el13 (24 kDa, Protein from Oryctolagus cuniculus)
- Large ribosomal subunit protein el18 (21 kDa, Protein from Oryctolagus cuniculus)
- Nascent polypeptide-associated complex subunit alpha (25 kDa, Protein from Homo sapiens)
- Ribosomal_l23en domain-containing protein (17 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l21 (18 kDa, Protein from Oryctolagus cuniculus)
- Mrna (543 Da, RNA from Oryctolagus cuniculus)
- Ribosomal protein l23 (14 kDa, Protein from Oryctolagus cuniculus)
- Zinc ion (65 Da, Ligand)
- 40s ribosomal protein s9 (22 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l19 (23 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l9 (21 kDa, Protein from Oryctolagus cuniculus)
- Nascent chain (2 kDa, Protein from Oryctolagus cuniculus)
- Nac heterodimer (Complex from Homo sapiens)
- Ribosomal protein l3 (46 kDa, Protein from Oryctolagus cuniculus)
- Rabbit ribosome-nascent chain complex (Complex from Oryctolagus cuniculus)
- 40s ribosomal protein s24 (15 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l34 (13 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s8 (24 kDa, Protein from Oryctolagus cuniculus)
- S10_plectin domain-containing protein (18 kDa, Protein from Oryctolagus cuniculus)
- Small ribosomal subunit protein us2 (32 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l31 (14 kDa, Protein from Oryctolagus cuniculus)
- Spermine (202 Da, Ligand)
- 60s ribosomal protein l41 (3 kDa, Protein from Oryctolagus cuniculus)
- Small ribosomal subunit protein us5 (31 kDa, Protein from Oryctolagus cuniculus)
- Small ribosomal subunit protein es21 (9 kDa, Protein from Oryctolagus cuniculus)
- Small ribosomal subunit protein rack1 (35 kDa, Protein from Oryctolagus cuniculus)
- Spermidine (145 Da, Ligand)
- Small ribosomal subunit protein us11 (16 kDa, Protein from Oryctolagus cuniculus)
- P-site trna (15 kDa, RNA from Oryctolagus cuniculus)
- 60s ribosomal protein l22 (14 kDa, Protein from Oryctolagus cuniculus)
- Transcription factor btf3 (17 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l30 (12 kDa, Protein from Oryctolagus cuniculus)
- Large ribosomal subunit protein el40 (14 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s12 (14 kDa, Protein from Oryctolagus cuniculus)
- Glutathione s-transferase class-mu 26 kda isozyme,n-alpha-acetyltransferase 50 (46 kDa, Protein from Homo sapiens)
- Human nata complex (Complex from Homo sapiens)
- 5s rrna (38 kDa, RNA from Oryctolagus cuniculus)
- 60s ribosomal protein l12 (17 kDa, Protein from Oryctolagus cuniculus)
- Small ribosomal subunit protein us10 (13 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein ul30 (29 kDa, Protein from Oryctolagus cuniculus)
- Large ribosomal subunit protein el20 (20 kDa, Protein from Oryctolagus cuniculus)
- Methionine aminopeptidase 1 (43 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ul4 (46 kDa, Protein from Oryctolagus cuniculus)
- 5.8s rrna (50 kDa, RNA from Oryctolagus cuniculus)
- 40s ribosomal protein es17 (15 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s30 (14 kDa, Protein from Oryctolagus cuniculus)
- Large ribosomal subunit protein ul22 (21 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s25 (13 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l35 (14 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s6 (28 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein s27a (18 kDa, Protein from Oryctolagus cuniculus)
- Magnesium ion (24 Da, Ligand)
- 60s ribosomal protein l6 (33 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l14 (23 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l36 (12 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein s5 (22 kDa, Protein from Oryctolagus cuniculus)
- Inositol hexakisphosphate (660 Da, Ligand)
- 60s ribosomal protein l27a (16 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein s15a (14 kDa, Protein from Oryctolagus cuniculus)
- Unknown atom or ion (Ligand)
- 40s ribosomal protein s23 (15 kDa, Protein from Oryctolagus cuniculus)
- Large ribosomal subunit protein ul18 (34 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l27 (15 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s3 (31 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s19 (16 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l29 (26 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l15 (24 kDa, Protein from Oryctolagus cuniculus)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Ribosomal protein l24 (17 kDa, Protein from Oryctolagus cuniculus)
- Small ribosomal subunit protein us13 (17 kDa, Protein from Oryctolagus cuniculus)
- Human nate with a gst tag (Complex from Homo sapiens)
- 60s ribosomal protein l11 (20 kDa, Protein from Oryctolagus cuniculus)
- Small ribosomal subunit protein es26 (13 kDa, Protein from Oryctolagus cuniculus)
- Human nata/e complex (Complex)
- Human methionine aminopeptidase 1 (Complex from Homo sapiens)
- 60s ribosomal protein l38 (8 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein us19 (17 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s28 (7 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s27 (9 kDa, Protein from Oryctolagus cuniculus)
- 28s rrna (1 MDa, RNA from Oryctolagus cuniculus)
- Large ribosomal subunit protein el28 (15 kDa, Protein from Oryctolagus cuniculus)
- 18s rrna (603 kDa, RNA from Oryctolagus cuniculus)
- Quaternary complex of a translating 80s ribosome, nac, metap1 and nata/e (3 MDa, Complex)
Mammalian quaternary complex of a translating 80S ribosome, NAC, MetAP1 and NatA/E-HYPK
Release date: Aug. 21, 2024
Resolution: 3.26 Å
EM Method: Single-particle
Fitted PDBs: 9f1d
Q-score: 0.447
Resolution: 3.26 Å
EM Method: Single-particle
Fitted PDBs: 9f1d
Q-score: 0.447
Lentzsch AM, Yudin D, Gamerdinger M, Chandrasekar S, Rabl L, Scaiola A, Deuerling E, Ban N, Shan SO
Nature (2024) 633 pp. 718-724 [ Pubmed: 39169182 DOI: doi:10.1038/s41586-024-07846-7 ]
Sample:
- 60s ribosomal protein l39-like (6 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l10 (24 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s7 (47 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s13 (17 kDa, Protein from Oryctolagus cuniculus)
- Small ribosomal subunit protein us9 (19 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l35a (12 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s3a (30 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l32 (15 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l37 (11 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s11 (18 kDa, Protein from Oryctolagus cuniculus)
- Large ribosomal subunit protein el42 (12 kDa, Protein from Oryctolagus cuniculus)
- Large ribosomal subunit protein ul2 (28 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s29 (6 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s4 (29 kDa, Protein from Oryctolagus cuniculus)
- Large ribosomal subunit protein ul13 (23 kDa, Protein from Oryctolagus cuniculus)
- Isoform 2 of huntingtin-interacting protein k (26 kDa, Protein from Homo sapiens)
- Ribosomal protein l26 (17 kDa, Protein from Oryctolagus cuniculus)
- N-alpha-acetyltransferase 10 (26 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l37a (10 kDa, Protein from Oryctolagus cuniculus)
- N-alpha-acetyltransferase 15, nata auxiliary subunit (106 kDa, Protein from Homo sapiens)
- Water (18 Da, Ligand)
- Large ribosomal subunit protein el13 (24 kDa, Protein from Oryctolagus cuniculus)
- Large ribosomal subunit protein el18 (21 kDa, Protein from Oryctolagus cuniculus)
- Ubiquitin-ribosomal protein el40 fusion protein (14 kDa, Protein from Oryctolagus cuniculus)
- Nascent polypeptide-associated complex subunit alpha (25 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l21 (18 kDa, Protein from Oryctolagus cuniculus)
- Mrna (543 Da, RNA from Oryctolagus cuniculus)
- Ribosomal protein l23 (14 kDa, Protein from Oryctolagus cuniculus)
- Zinc ion (65 Da, Ligand)
- 40s ribosomal protein s9 (22 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l19 (23 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l9 (21 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l3 (46 kDa, Protein from Oryctolagus cuniculus)
- Large ribosomal subunit protein el8 (30 kDa, Protein from Oryctolagus cuniculus)
- Rabbit ribosome-nascent chain complex (Complex from Oryctolagus cuniculus)
- Human nac heterodimer (Complex from Homo sapiens)
- 40s ribosomal protein s24 (15 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l34 (13 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s8 (24 kDa, Protein from Oryctolagus cuniculus)
- S10_plectin domain-containing protein (18 kDa, Protein from Oryctolagus cuniculus)
- Small ribosomal subunit protein us2 (32 kDa, Protein from Oryctolagus cuniculus)
- Human nata/e-hypk complex (Complex)
- 60s ribosomal protein l31 (14 kDa, Protein from Oryctolagus cuniculus)
- Spermine (202 Da, Ligand)
- 60s ribosomal protein l41 (3 kDa, Protein from Oryctolagus cuniculus)
- Small ribosomal subunit protein us5 (31 kDa, Protein from Oryctolagus cuniculus)
- Small ribosomal subunit protein es21 (9 kDa, Protein from Oryctolagus cuniculus)
- Small ribosomal subunit protein rack1 (35 kDa, Protein from Oryctolagus cuniculus)
- Spermidine (145 Da, Ligand)
- Glutathione s-transferase class-mu 26 kda isozyme,n-alpha-acetyltransferase 50,n-alpha-acetyltransferase 50 (46 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein us11 (16 kDa, Protein from Oryctolagus cuniculus)
- Human hypk (Complex from Homo sapiens)
- P-site trna (15 kDa, RNA from Oryctolagus cuniculus)
- 60s ribosomal protein l22 (14 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l30 (12 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s12 (14 kDa, Protein from Oryctolagus cuniculus)
- Human nata complex (Complex from Homo sapiens)
- 60s ribosomal protein l12 (17 kDa, Protein from Oryctolagus cuniculus)
- 5s rrna (38 kDa, RNA from Oryctolagus cuniculus)
- Ribosomal protein ul30 (29 kDa, Protein from Oryctolagus cuniculus)
- Large ribosomal subunit protein el20 (20 kDa, Protein from Oryctolagus cuniculus)
- Methionine aminopeptidase 1 (43 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ul4 (46 kDa, Protein from Oryctolagus cuniculus)
- 5.8s rrna (50 kDa, RNA from Oryctolagus cuniculus)
- 40s ribosomal protein es17 (15 kDa, Protein from Oryctolagus cuniculus)
- Nascent chain (2 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s30 (14 kDa, Protein from Oryctolagus cuniculus)
- Large ribosomal subunit protein ul22 (21 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s25 (13 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l35 (14 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s6 (28 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein s27a (18 kDa, Protein from Oryctolagus cuniculus)
- Magnesium ion (24 Da, Ligand)
- 60s ribosomal protein l6 (33 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l14 (23 kDa, Protein from Oryctolagus cuniculus)
- Quaternary complex of a translating 80s ribosome, nac, metap1 and nata/e-hypk (3 MDa, Complex)
- 60s ribosomal protein l36 (12 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein s5 (22 kDa, Protein from Oryctolagus cuniculus)
- Inositol hexakisphosphate (660 Da, Ligand)
- 60s ribosomal protein l27a (16 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein s15a (14 kDa, Protein from Oryctolagus cuniculus)
- Unknown atom or ion (Ligand)
- 40s ribosomal protein s23 (15 kDa, Protein from Oryctolagus cuniculus)
- Large ribosomal subunit protein ul18 (34 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l27 (15 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s3 (31 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s19 (16 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l29 (26 kDa, Protein from Oryctolagus cuniculus)
- Ribosomal protein l15 (24 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein us10 (13 kDa, Protein from Oryctolagus cuniculus)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Ribosomal protein l24 (17 kDa, Protein from Oryctolagus cuniculus)
- Small ribosomal subunit protein us13 (17 kDa, Protein from Oryctolagus cuniculus)
- Human nate with a gst tag (Complex from Homo sapiens)
- Large ribosomal subunit protein ul10 (34 kDa, Protein from Oryctolagus cuniculus)
- 60s ribosomal protein l11 (20 kDa, Protein from Oryctolagus cuniculus)
- Small ribosomal subunit protein es26 (13 kDa, Protein from Oryctolagus cuniculus)
- Human methionine aminopeptidase 1 (Complex from Homo sapiens)
- 60s ribosomal protein l38 (8 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein us19 (17 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s28 (7 kDa, Protein from Oryctolagus cuniculus)
- 40s ribosomal protein s27 (9 kDa, Protein from Oryctolagus cuniculus)
- 28s rrna (1 MDa, RNA from Oryctolagus cuniculus)
- Large ribosomal subunit protein el28 (15 kDa, Protein from Oryctolagus cuniculus)
- 18s rrna (603 kDa, RNA from Oryctolagus cuniculus)
- Isoform 2 of transcription factor btf3 (17 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ul23 (17 kDa, Protein from Oryctolagus cuniculus)
CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME WITH A/P/E-site tRNA AND mRNA : PARENTAL STRAIN
Release date: May 15, 2024
Resolution: 2.93 Å
EM Method: Single-particle
Fitted PDBs: 8rxh
Q-score: 0.603
Resolution: 2.93 Å
EM Method: Single-particle
Fitted PDBs: 8rxh
Q-score: 0.603
Rajan KS, Aryal S, Hiregange DG, Bashan A, Madmoni H, Olami M, Doniger T, Cohen-Chalamish S, Pescher P, Taoka M, Nobe Y, Fedorenko A, Bose T, Zimermann E, Prina E, Aharon-Hefetz N, Pilpel Y, Isobe T, Unger R, Spath GF, Yonath A, Michaeli S
Cell Rep (2024) 43 pp. 114203-114203 [ Pubmed: 38722744 DOI: doi:10.1016/j.celrep.2024.114203 ]
Sample:
- 60s ribosomal protein l37a (10 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s5 (21 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s19-like protein (18 kDa, Protein from Leishmania major strain Friedlin)
- E-site_trna_chain_s4 (24 kDa, RNA from Leishmania major strain Friedlin)
- Putative rna binding protein (25 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l28 (16 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s4 (30 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s15 (17 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s21 (17 kDa, Protein from Leishmania major strain Friedlin)
- Potassium ion (39 Da, Ligand)
- Putative 40s ribosomal protein s16 (16 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l27 (15 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l36 (11 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l30 (11 kDa, Protein from Leishmania major strain Friedlin)
- Water (18 Da, Ligand)
- Putative 60s ribosomal protein l35 (15 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l39 (6 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l32 (15 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l23a (16 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s18 (17 kDa, Protein from Leishmania major strain Friedlin)
- Sr2_chain_4 (59 kDa, RNA from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein l14 (19 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein l35a (16 kDa, Protein from Leishmania major strain Friedlin)
- Zinc ion (65 Da, Ligand)
- Putative 60s ribosomal protein l27a/l29 (16 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein l24 (14 kDa, Protein from Leishmania major strain Friedlin)
- A-site_trna_chain_s2 (24 kDa, RNA from Leishmania major strain Friedlin)
- 5s_rrna_chain_8 (39 kDa, RNA from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l34 (19 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s14 (15 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l18 (22 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s26 (12 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l7 (28 kDa, Protein from Leishmania major strain Friedlin)
- P-site_trna_chain_s3 (24 kDa, RNA from Leishmania major strain Friedlin)
- Ribosomal protein s17 family protein (20 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l29 (8 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l26 (16 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l19 (28 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l9 (21 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l21 (18 kDa, Protein from Leishmania major strain Friedlin)
- Sr4_chain_5 (43 kDa, RNA from Leishmania major strain Friedlin)
- 40s ribosomal protein s30 (7 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l5 (34 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l44 (12 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s23 (15 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l2 (28 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l13 (24 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s3 (24 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s24 (15 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s12 (15 kDa, Protein from Leishmania major strain Friedlin)
- Lsua_rrna_chain_1 (577 kDa, RNA from Leishmania major strain Friedlin)
- Mrna_chain_s5 (4 kDa, RNA from Leishmania major strain Friedlin)
- Putative ribosomal protein s29 (6 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s2 (28 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l11 (21 kDa, Protein from Leishmania major strain Friedlin)
- Guanine nucleotide-binding protein subunit beta-like protein (34 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l17 (19 kDa, Protein from Leishmania major strain Friedlin)
- Ssu_rrna_chain_s1 (710 kDa, RNA from Leishmania major strain Friedlin)
- 60s ribosomal protein l41 (4 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l22 (15 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s10 (18 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l6 (21 kDa, Protein from Leishmania major strain Friedlin)
- Lsub_rrna_chain_2 (492 kDa, RNA from Leishmania major strain Friedlin)
- Putative ribosomal protein s20 (13 kDa, Protein from Leishmania major strain Friedlin)
- Ubiquitin-60s ribosomal protein l40 (14 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s25 (13 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s8 (24 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s7 (23 kDa, Protein from Leishmania major strain Friedlin)
- Magnesium ion (24 Da, Ligand)
- 60s ribosomal protein l18a (20 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein l1a (41 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s13 (17 kDa, Protein from Leishmania major strain Friedlin)
- Ribosomal protein l15 (24 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s3a (30 kDa, Protein from Leishmania major strain Friedlin)
- Sodium ion (22 Da, Ligand)
- (2s)-2-[2-[4-[[(2r,3s,4s)-3-acetyloxy-4-oxidanyl-pyrrolidin-2-yl]methyl]phenoxy]ethanoylamino]-6-azanyl-hexanoic acid (437 Da, Ligand)
- Ubiquitin-60s ribosomal protein l40 (17 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l7a (29 kDa, Protein from Leishmania major strain Friedlin)
- Sr6_chain_6 (23 kDa, RNA from Leishmania major strain Friedlin)
- 5.8s_rrna_chain_7 (54 kDa, RNA from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s27-1 (9 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l13a (25 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein l38 (9 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal subunit protein l31 (21 kDa, Protein from Leishmania major strain Friedlin)
- Ribosomal protein l37 (9 kDa, Protein from Leishmania major strain Friedlin)
- Cryo-em structure of leishmania major 80s ribosome with a/p/e-site trna and mrna (Complex from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s15a (14 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s17 (16 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s9 (22 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s6 (28 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l10 (24 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein l3 (47 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l23 (14 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein sa (27 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s33 (9 kDa, Protein from Leishmania major strain Friedlin)
- Sr1_chain_3 (69 kDa, RNA from Leishmania major strain Friedlin)
Release date: May 15, 2024
Resolution: 2.97 Å
EM Method: Single-particle
Fitted PDBs: 8rxx
Q-score: 0.601
Resolution: 2.97 Å
EM Method: Single-particle
Fitted PDBs: 8rxx
Q-score: 0.601
Rajan KS, Aryal S, Hiregange DG, Bashan A, Madmoni H, Olami M, Doniger T, Cohen-Chalamish S, Pescher P, Taoka M, Nobe Y, Fedorenko A, Bose T, Zimermann E, Prina E, Aharon-Hefetz N, Pilpel Y, Isobe T, Unger R, Spath GF, Yonath A, Michaeli S
Cell Rep (2024) 43 pp. 114203-114203 [ Pubmed: 38722744 DOI: doi:10.1016/j.celrep.2024.114203 ]
Sample:
- 60s ribosomal protein l37a (10 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s5 (21 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s19-like protein (18 kDa, Protein from Leishmania major strain Friedlin)
- E-site_trna_chain_s4 (24 kDa, RNA from Leishmania major strain Friedlin)
- Putative rna binding protein (25 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l28 (16 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s4 (30 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s15 (17 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s21 (17 kDa, Protein from Leishmania major strain Friedlin)
- Potassium ion (39 Da, Ligand)
- Putative 40s ribosomal protein s16 (16 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l27 (15 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l36 (11 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l30 (11 kDa, Protein from Leishmania major strain Friedlin)
- Water (18 Da, Ligand)
- Putative 60s ribosomal protein l35 (15 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l39 (6 kDa, Protein from Leishmania major strain Friedlin)
- Ssu_rrna_chain_s1 (710 kDa, RNA from Leishmania major strain Friedlin)
- 60s ribosomal protein l32 (15 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l23a (16 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s18 (17 kDa, Protein from Leishmania major strain Friedlin)
- Sr2_chain_4 (59 kDa, RNA from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein l14 (19 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein l35a (16 kDa, Protein from Leishmania major strain Friedlin)
- Zinc ion (65 Da, Ligand)
- Putative 60s ribosomal protein l27a/l29 (16 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein l24 (14 kDa, Protein from Leishmania major strain Friedlin)
- A-site_trna_chain_s2 (24 kDa, RNA from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l34 (19 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s14 (15 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l18 (22 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s26 (12 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l7 (28 kDa, Protein from Leishmania major strain Friedlin)
- P-site_trna_chain_s3 (24 kDa, RNA from Leishmania major strain Friedlin)
- Ribosomal protein s17 family protein (20 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l29 (8 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l26 (16 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l19 (28 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l9 (21 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l21 (18 kDa, Protein from Leishmania major strain Friedlin)
- Lsua_rrna_chain_1 (577 kDa, RNA from Leishmania major strain Friedlin)
- 40s ribosomal protein s30 (7 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l5 (34 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l44 (12 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s23 (15 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l2 (28 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l13 (24 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s3 (24 kDa, Protein from Leishmania major strain Friedlin)
- Lsub_rrna_chain_2 (492 kDa, RNA from Leishmania major strain Friedlin)
- 40s ribosomal protein s24 (15 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s12 (15 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein s29 (6 kDa, Protein from Leishmania major strain Friedlin)
- Mrna_chain_s5 (4 kDa, RNA from Leishmania major strain Friedlin)
- Guanine nucleotide-binding protein subunit beta-like protein (34 kDa, Protein from Leishmania major strain Friedlin)
- 5s_rrna_chain_8 (39 kDa, RNA from Leishmania major strain Friedlin)
- 60s ribosomal protein l11 (21 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s2 (28 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l17 (19 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l41 (4 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l22 (15 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s10 (18 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l6 (21 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein s20 (13 kDa, Protein from Leishmania major strain Friedlin)
- Ubiquitin-60s ribosomal protein l40 (14 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s25 (13 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s8 (24 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s7 (23 kDa, Protein from Leishmania major strain Friedlin)
- Magnesium ion (24 Da, Ligand)
- 60s ribosomal protein l18a (20 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein l1a (41 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s13 (17 kDa, Protein from Leishmania major strain Friedlin)
- Ribosomal protein l15 (24 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s3a (30 kDa, Protein from Leishmania major strain Friedlin)
- Sodium ion (22 Da, Ligand)
- Ubiquitin-60s ribosomal protein l40 (17 kDa, Protein from Leishmania major strain Friedlin)
- 80s ribosome with a/p/e-site trna and mrna (Complex from Leishmania major strain Friedlin)
- 60s ribosomal protein l7a (29 kDa, Protein from Leishmania major strain Friedlin)
- Sr6_chain_6 (23 kDa, RNA from Leishmania major strain Friedlin)
- 5.8s_rrna_chain_7 (54 kDa, RNA from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s27-1 (9 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l13a (25 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein l38 (9 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal subunit protein l31 (21 kDa, Protein from Leishmania major strain Friedlin)
- Ribosomal protein l37 (9 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s15a (14 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s17 (16 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s9 (22 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s6 (28 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l10 (24 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein l3 (47 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l23 (14 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein sa (27 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s33 (9 kDa, Protein from Leishmania major strain Friedlin)
- Sr1_chain_3 (69 kDa, RNA from Leishmania major strain Friedlin)
- Sr4_chain_5 (43 kDa, RNA from Leishmania major strain Friedlin)
CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME : PARENTAL STRAIN
Release date: May 8, 2024
Resolution: 2.4 Å
EM Method: Single-particle
Fitted PDBs: 8ovj
Q-score: 0.63
Resolution: 2.4 Å
EM Method: Single-particle
Fitted PDBs: 8ovj
Q-score: 0.63
Rajan KS, Aryal S, Hiregange DG, Bashan A, Madmoni H, Olami M, Doniger T, Cohen-Chalamish S, Pescher P, Taoka M, Nobe Y, Fedorenko A, Bose T, Zimermann E, Prina E, Aharon-Hefetz N, Pilpel Y, Isobe T, Unger R, Spath GF, Yonath A, Michaeli S
Cell Rep (2024) 43 pp. 114203-114203 [ Pubmed: 38722744 DOI: doi:10.1016/j.celrep.2024.114203 ]
Sample:
- 40s ribosomal protein s5 (21 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l37a (10 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s19-like protein (18 kDa, Protein from Leishmania major strain Friedlin)
- Putative rna binding protein (25 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s4 (30 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l28 (16 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s15 (17 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s21 (17 kDa, Protein from Leishmania major strain Friedlin)
- Potassium ion (39 Da, Ligand)
- Putative 40s ribosomal protein s16 (16 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l27 (15 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l36 (11 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l30 (11 kDa, Protein from Leishmania major strain Friedlin)
- Water (18 Da, Ligand)
- Putative 60s ribosomal protein l35 (15 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l39 (6 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l32 (15 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l23a (16 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s18 (17 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein l14 (19 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein l35a (16 kDa, Protein from Leishmania major strain Friedlin)
- Zinc ion (65 Da, Ligand)
- Putative 60s ribosomal protein l27a/l29 (16 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein l24 (14 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l34 (19 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s14 (15 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s26 (12 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l18 (22 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l7 (28 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l29 (8 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l26 (16 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l19 (28 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l9 (21 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l21 (18 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s30 (7 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l5 (34 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l44 (12 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s23 (15 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l2 (28 kDa, Protein from Leishmania major strain Friedlin)
- Sr2_chain_4 (59 kDa, RNA from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l13 (24 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s3 (24 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s24 (15 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s11 (20 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s12 (15 kDa, Protein from Leishmania major strain Friedlin)
- Lsub_rrna_chain_2 (492 kDa, RNA from Leishmania major strain Friedlin)
- Lsua_rrna_chain_1 (577 kDa, RNA from Leishmania major strain Friedlin)
- Guanine nucleotide-binding protein subunit beta-like protein (34 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein s29 (6 kDa, Protein from Leishmania major strain Friedlin)
- 5s_rrna_chain_8 (39 kDa, RNA from Leishmania major strain Friedlin)
- 60s ribosomal protein l11 (21 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s2 (28 kDa, Protein from Leishmania major strain Friedlin)
- E-site_trna_chain_s4 (6 kDa, RNA from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l17 (19 kDa, Protein from Leishmania major strain Friedlin)
- 60s ribosomal protein l41 (4 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l22 (15 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s10 (18 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l6 (21 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein s20 (13 kDa, Protein from Leishmania major strain Friedlin)
- Ubiquitin-60s ribosomal protein l40 (14 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s25 (13 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s8 (24 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s7 (23 kDa, Protein from Leishmania major strain Friedlin)
- Magnesium ion (24 Da, Ligand)
- 60s ribosomal protein l18a (20 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein l1a (41 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s13 (17 kDa, Protein from Leishmania major strain Friedlin)
- Ribosomal protein l15 (24 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s3a (30 kDa, Protein from Leishmania major strain Friedlin)
- Sodium ion (22 Da, Ligand)
- Ssu_rrna_chain_s1 (710 kDa, RNA from Leishmania major strain Friedlin)
- 60s ribosomal protein l7a (29 kDa, Protein from Leishmania major strain Friedlin)
- Sr6_chain_6 (23 kDa, RNA from Leishmania major strain Friedlin)
- 5.8s_rrna_chain_7 (54 kDa, RNA from Leishmania major strain Friedlin)
- 80s ribosome from leishmania major (Complex from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s27-1 (9 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l13a (25 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein l38 (9 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal subunit protein l31 (21 kDa, Protein from Leishmania major strain Friedlin)
- Ribosomal protein l37 (9 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s15a (14 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s17 (16 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s9 (22 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein s6 (28 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l10 (24 kDa, Protein from Leishmania major strain Friedlin)
- Putative ribosomal protein l3 (47 kDa, Protein from Leishmania major strain Friedlin)
- Putative 60s ribosomal protein l23 (14 kDa, Protein from Leishmania major strain Friedlin)
- 40s ribosomal protein sa (27 kDa, Protein from Leishmania major strain Friedlin)
- Putative 40s ribosomal protein s33 (9 kDa, Protein from Leishmania major strain Friedlin)
- Sr1_chain_3 (69 kDa, RNA from Leishmania major strain Friedlin)
- Sr4_chain_5 (43 kDa, RNA from Leishmania major strain Friedlin)
UFL1 E3 ligase bound 60S ribosome
Release date: Feb. 21, 2024
Resolution: 2.2 Å
EM Method: Single-particle
Fitted PDBs: 8qfd
Q-score: 0.684
Resolution: 2.2 Å
EM Method: Single-particle
Fitted PDBs: 8qfd
Q-score: 0.684
Makhlouf L, Peter JJ, Magnussen HM, Thakur R, Millrine D, Minshull TC, Harrison G, Varghese J, Lamoliatte F, Foglizzo M, Macartney T, Calabrese AN, Zeqiraj E, Kulathu Y
Nature (2024) 627 pp. 437-444 [ DOI: doi:10.1038/s41586-024-07093-w Pubmed: 38383789 ]
Sample:
- 60s ribosomal protein l21 (18 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l29 (17 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l3 (46 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l35 (14 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l35a (12 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l23 (14 kDa, Protein from Homo sapiens)
- 5s rrna (38 kDa, RNA from Homo sapiens)
- 60s ribosomal protein l28 (15 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l39 (6 kDa, Protein from Homo sapiens)
- 28s rrna (1 MDa, RNA from Homo sapiens)
- 60s ribosomal protein l38 (8 kDa, Protein from Homo sapiens)
- Ufm1 ribosome e3 ligase complex (Complex from Homo sapiens)
- 60s ribosomal protein l9 (21 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l36 (12 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l17 (21 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l8 (28 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l24 (17 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l15 (24 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l23a (17 kDa, Protein from Homo sapiens)
- Water (18 Da, Ligand)
- 60s ribosomal protein l36a (12 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ul30 (29 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l19 (23 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l5 (34 kDa, Protein from Homo sapiens)
- 60s ribosome bound by the ufm1 ribosome e3 ligase complex. (Complex from Homo sapiens)
- 60s ribosomal protein l10 (24 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l27a (16 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l30 (12 kDa, Protein from Homo sapiens)
- Ribosomal protein l37 (11 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- 60s ribosomal protein l27 (15 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l13a (23 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l11 (20 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l6 (32 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l34 (13 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l14 (23 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l4 (47 kDa, Protein from Homo sapiens)
- E3 ufm1-protein ligase 1 (91 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l31 (14 kDa, Protein from Homo sapiens)
- 5.8s rrna (50 kDa, RNA from Homo sapiens)
- 60s ribosomal protein l7a (30 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l22 (14 kDa, Protein from Homo sapiens)
- Ubiquitin-60s ribosomal protein l40 (14 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- 60s ribosomal protein l13 (24 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l18 (21 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l18a (20 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l26 (17 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l32 (15 kDa, Protein from Homo sapiens)
- 60s ribosomal protein l37a (10 kDa, Protein from Homo sapiens)