Resolution: 2.49 Å
EM Method: Single-particle
Fitted PDBs: 8wpw
Q-score: 0.542
Su C, He JH, Qi JX, Yang MS, Wang QH, Gao GF
To Be Published
- Cryo-em structure of sars-cov-2 xbb.1.5 receptor-binding domain (rbd) complexed with cb6 mutant,s309, and s304 antibodies (Complex from Homo sapiens)
- Spike protein s1 (25 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- S304 fab light chain (23 kDa, Protein from Homo sapiens)
- Sars-cov-2 xbb.1.5 rbd (Complex)
- S309 fab heavy chain (25 kDa, Protein from Homo sapiens)
- Cb6 fab mutant heavy chain (24 kDa, Protein from Homo sapiens)
- Cb6 fab mutant light chain (23 kDa, Protein from Homo sapiens)
- S304 fab heavy chain (24 kDa, Protein from Homo sapiens)
- S309 fab light chain (23 kDa, Protein from Homo sapiens)
- Fab (Complex from Severe acute respiratory syndrome-related coronavirus)
Resolution: 3.02 Å
EM Method: Single-particle
Fitted PDBs: 8wpy
Q-score: 0.488
Su C, He JH, Qi JX, Yang MS, Wang QH, Gao GF
To Be Published
- Cryo-em structure of sars-cov-2 receptor-binding domain (rbd) complexed with cb6 mutant,s309, and s304 antibodies (Complex from Homo sapiens)
- S304 fab light chain (23 kDa, Protein from Homo sapiens)
- S309 fab heavy chain (25 kDa, Protein from Homo sapiens)
- Cb6 fab mutant heavy chain (24 kDa, Protein from Homo sapiens)
- Cb6 fab mutant light chain (23 kDa, Protein from Homo sapiens)
- Sars-cov-2 rbd (Complex)
- Spike protein s1 (25 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- S304 fab heavy chain (24 kDa, Protein from Homo sapiens)
- S309 fab light chain (23 kDa, Protein from Homo sapiens)
- Fab (Complex from Severe acute respiratory syndrome-related coronavirus)
SARS-CoV-2 Omicron XBB.1.5 RBD complexed with human ACE2 and S304
Resolution: 2.91 Å
EM Method: Single-particle
Fitted PDBs: 8we4
Q-score: 0.462
Li W, Xu Z, Niu T, Xie Y, Zhao Z, Li D, He Q, Sun W, Shi K, Guo W, Chang Z, Liu K, Fan Z, Qi J, Gao GF
EMBO J (2024) 43 pp. 1484-1498 [ DOI: doi:10.1038/s44318-024-00062-z Pubmed: 38467833 ]
- S304 fab light chain (23 kDa, Protein from Homo sapiens)
- Fabs304 (Complex from Homo sapiens)
- S304 fab heavy chain (24 kDa, Protein from Homo sapiens)
- Sars-cov-2 omicron xbb.1.5 rbd complexed with human ace2 and fab s304 (Complex)
- Zinc ion (65 Da, Ligand)
- Ace2 (Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Spike protein s1 (25 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2 omicron xbb.1.5 rbd (Complex from Severe acute respiratory syndrome coronavirus 2)
- Angiotensin-converting enzyme 2 (92 kDa, Protein from Homo sapiens)
The complex structure of Omicron BA.4 RBD with BD604, S309, and S304
Resolution: 2.36 Å
EM Method: Single-particle
Fitted PDBs: 8hws
Q-score: 0.472
He Q, Wu L, Xu Z, Wang X, Xie Y, Chai Y, Zheng A, Zhou J, Qiao S, Huang M, Shang G, Zhao X, Feng Y, Qi J, Gao GF, Wang Q
Cell Rep Med (2023) 4 pp. 100991-100991 [ DOI: doi:10.1016/j.xcrm.2023.100991 Pubmed: 37019110 ]
- Spike protein s2' (22 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- S304 fab light chain (23 kDa, Protein from Homo sapiens)
- S304 fab heavy chain (24 kDa, Protein from Homo sapiens)
- S309 fab heavy chain (25 kDa, Protein from Homo sapiens)
- Omicron ba.4/5 rbd in complex with fabs of bd-604, s304 and s309 (Complex from Homo sapiens)
- Bd-604 fab heavy chain (24 kDa, Protein from Homo sapiens)
- S309 fab light chain (23 kDa, Protein from Homo sapiens)
- Bd-604 fab light chain (23 kDa, Protein from Homo sapiens)
The complex structure of Omicron BA.1 RBD with BD604, S309,and S304
Resolution: 2.74 Å
EM Method: Single-particle
Fitted PDBs: 7x1m
Q-score: 0.552
Huang M, Wu L, Zheng A, Xie Y, He Q, Rong X, Han P, Du P, Han P, Zhang Z, Zhao R, Jia Y, Li L, Bai B, Hu Z, Hu S, Niu S, Hu Y, Liu H, Liu B, Cui K, Li W, Zhao X, Liu K, Qi J, Wang Q, Gao GF
Immunity (2022) 55 pp. 1501-1514.e3 [ DOI: doi:10.1016/j.immuni.2022.06.005 Pubmed: 35777362 ]
- Bd604 fab, s309 fab and s304 fab complex with omicron ba.1 rbd (Complex)
- S309 fab heavy chain (24 kDa, Protein from Homo sapiens)
- S304 fab haavy chain (23 kDa, Protein from Homo sapiens)
- Bd-604 fab light chain (23 kDa, Protein from Homo sapiens)
- Bd604 fab, s309 fab and s304 fab (Complex from Homo sapiens)
- Omicron ba.1 rbd (Complex from Severe acute respiratory syndrome coronavirus 2)
- Bd-604 fab heavy chain (23 kDa, Protein from Homo sapiens)
- S309 fab light chain (23 kDa, Protein from Homo sapiens)
- Spike protein s1 (23 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- S304 fab light chain (23 kDa, Protein from Homo sapiens)
SARS-CoV-2 spike in complex with the S304 neutralizing antibody Fab fragment
Resolution: 4.3 Å
EM Method: Single-particle
Fitted PDBs: 7jw0
Q-score: 0.338
Piccoli L, Park YJ, Tortorici MA, Czudnochowski N, Walls AC, Beltramello M, Silacci-Fregni C, Pinto D, Rosen LE, Bowen JE, Acton OJ, Jaconi S, Guarino B, Minola A, Zatta F, Sprugasci N, Bassi J, Peter A, De Marco A, Nix JC, Mele F, Jovic S, Rodriguez BF, Gupta SV, Jin F, Piumatti G, Lo Presti G, Pellanda AF, Biggiogero M, Tarkowski M, Pizzuto MS, Cameroni E, Havenar-Daughton C, Smithey M, Hong D, Lepori V, Albanese E, Ceschi A, Bernasconi E, Elzi L, Ferrari P, Garzoni C, Riva A, Snell G, Sallusto F, Fink K, Virgin HW, Lanzavecchia A, Corti D, Veesler D
Cell (2020) 183 pp. 1024-1042.e21 [ Pubmed: 32991844 DOI: doi:10.1016/j.cell.2020.09.037 ]
- S304 neutralizing antibody fab fragment (Complex from Homo sapiens)
- Sars-cov-2 spike in complex (Complex from Severe acute respiratory syndrome coronavirus 2)
- S304 fab heavy chain (23 kDa, Protein from Homo sapiens)
- Spike glycoprotein (141 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2 spike in complex with the s304 neutralizing antibody fab fragment (Complex)
- S304 fab light chain (23 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)