Resolution: 2.08 Å
EM Method: Single-particle
Fitted PDBs: 7zyl
Q-score: 0.675
SsoMCM hexamer bound to Mg/ADP-BeFx and 12-mer oligo-dT. Class 1
Resolution: 2.62 Å
EM Method: Single-particle
Fitted PDBs: 8eaf
Q-score: 0.497
Meagher M, Myasnikov A, Enemark EJ
Int J Mol Sci (2022) 23 [ Pubmed: 36499022 DOI: doi:10.3390/ijms232314678 ]
- [[[(2r,3s,4r,5r)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-tris(fluoranyl)beryllium (492 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Ssomcm hexamer bound to mg/adp-befx and 12-mer oligo-dt. class 1. (Complex from Saccharolobus solfataricus P2)
- 12-mer oligo dt (3 kDa, DNA from synthetic construct)
- Minichromosome maintenance protein mcm (68 kDa, Protein from Saccharolobus solfataricus P2)
- Magnesium ion (24 Da, Ligand)
- Water (18 Da, Ligand)
SsoMCM hexamer bound to Mg/ADP-BeFx and 12-mer oligo-dT. Class 2
Resolution: 3.01 Å
EM Method: Single-particle
Fitted PDBs: 8eag
Q-score: 0.432
Meagher M, Myasnikov A, Enemark EJ
Int J Mol Sci (2022) 23 [ Pubmed: 36499022 DOI: doi:10.3390/ijms232314678 ]
- [[[(2r,3s,4r,5r)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-tris(fluoranyl)beryllium (492 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- 12-mer oligo-dt (3 kDa, DNA from synthetic construct)
- Minichromosome maintenance protein mcm (68 kDa, Protein from Saccharolobus solfataricus P2)
- Magnesium ion (24 Da, Ligand)
- Ssomcm hexamer bound to mg/adp-befx and 12-mer oligo-dt. class 2. (Complex from Saccharolobus solfataricus P2)
- Water (18 Da, Ligand)
SsoMCM hexamer bound to Mg/ADP-BeFx and 16-mer oligo-dT. Class 1
Resolution: 2.48 Å
EM Method: Single-particle
Fitted PDBs: 8eah
Q-score: 0.509
Meagher M, Myasnikov A, Enemark EJ
Int J Mol Sci (2022) 23 [ Pubmed: 36499022 DOI: doi:10.3390/ijms232314678 ]
- [[[(2r,3s,4r,5r)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-tris(fluoranyl)beryllium (492 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- 16-mer oligo-dt (4 kDa, DNA from synthetic construct)
- Minichromosome maintenance protein mcm (68 kDa, Protein from Saccharolobus solfataricus P2)
- Magnesium ion (24 Da, Ligand)
- Water (18 Da, Ligand)
- Ssomcm hexamer bound to mg/adp-befx and 16-mer oligo-dt class 1 (Complex from Saccharolobus solfataricus P2)
SsoMCM hexamer bound to Mg/ADP-BeFx and 16-mer oligo-dT. Class 2
Resolution: 2.76 Å
EM Method: Single-particle
Fitted PDBs: 8eai
Q-score: 0.465
Meagher M, Myasnikov A, Enemark EJ
Int J Mol Sci (2022) 23 [ Pubmed: 36499022 DOI: doi:10.3390/ijms232314678 ]
- [[[(2r,3s,4r,5r)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-tris(fluoranyl)beryllium (492 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Mcm hexamer bound to mg/adp-befx and 16-mer oligo-dt. class 2 (Complex from Saccharolobus solfataricus P2)
- 16-mer oligo-dt (4 kDa, DNA from synthetic construct)
- Minichromosome maintenance protein mcm (68 kDa, Protein from Saccharolobus solfataricus P2)
- Magnesium ion (24 Da, Ligand)
- Water (18 Da, Ligand)
SsoMCM hexamer bound to Mg/ADP-BeFx and 46-mer DNA strand. Class 1
Resolution: 2.45 Å
EM Method: Single-particle
Fitted PDBs: 8eaj
Q-score: 0.505
Meagher M, Myasnikov A, Enemark EJ
Int J Mol Sci (2022) 23 [ Pubmed: 36499022 DOI: doi:10.3390/ijms232314678 ]
- [[[(2r,3s,4r,5r)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-tris(fluoranyl)beryllium (492 Da, Ligand)
- 46-mer dna strand (13 kDa, DNA from synthetic construct)
- Zinc ion (65 Da, Ligand)
- Ssomcm hexamer bound to mg/adp-befx and 46-mer dna strand. class 1. (Complex from Saccharolobus solfataricus P2)
- Minichromosome maintenance protein mcm (68 kDa, Protein from Saccharolobus solfataricus P2)
- Magnesium ion (24 Da, Ligand)
- Water (18 Da, Ligand)
SsoMCM hexamer bound to Mg/ADP-BeFx and 46-mer DNA strand. Class 2
Resolution: 2.67 Å
EM Method: Single-particle
Fitted PDBs: 8eak
Q-score: 0.48
Meagher M, Myasnikov A, Enemark EJ
Int J Mol Sci (2022) 23 [ Pubmed: 36499022 DOI: doi:10.3390/ijms232314678 ]
- [[[(2r,3s,4r,5r)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-tris(fluoranyl)beryllium (492 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- 46-mer dna (13 kDa, DNA from synthetic construct)
- Ssomcm hexamer bound to mg/adp-befx and 46-mer dna strand class 2 (Complex from Saccharolobus solfataricus P2)
- Minichromosome maintenance protein mcm (68 kDa, Protein from Saccharolobus solfataricus P2)
- Magnesium ion (24 Da, Ligand)
- Water (18 Da, Ligand)
Resolution: 2.34 Å
EM Method: Single-particle
Fitted PDBs: 8eal
Q-score: 0.518
Meagher M, Myasnikov A, Enemark EJ
Int J Mol Sci (2022) 23 [ Pubmed: 36499022 DOI: doi:10.3390/ijms232314678 ]
- Dna (3 kDa, DNA from synthetic construct)
- [[[(2r,3s,4r,5r)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-tris(fluoranyl)beryllium (492 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Ssomcm hexamer bound to mg/adp-befx and dna. class 2. merged particles from datasets with 3 different dna entities. (Complex from Saccharolobus solfataricus P2)
- Minichromosome maintenance protein mcm (68 kDa, Protein from Saccharolobus solfataricus P2)
- Magnesium ion (24 Da, Ligand)
- Water (18 Da, Ligand)
Resolution: 2.59 Å
EM Method: Single-particle
Fitted PDBs: 8eam
Q-score: 0.485
Meagher M, Myasnikov A, Enemark EJ
Int J Mol Sci (2022) 23 [ Pubmed: 36499022 DOI: doi:10.3390/ijms232314678 ]
- Dna (3 kDa, DNA from synthetic construct)
- [[[(2r,3s,4r,5r)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-tris(fluoranyl)beryllium (492 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Ssomcm hexamer bound to mg/adp-befx and dna. class 2. merged particles from datasets with 3 different dna entities. (Complex from Saccharolobus solfataricus P2)
- Minichromosome maintenance protein mcm (68 kDa, Protein from Saccharolobus solfataricus P2)
- Magnesium ion (24 Da, Ligand)
- Water (18 Da, Ligand)