Human L-type voltage-gated calcium channel Cav1.2 at 2.9 Angstrom resolution
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8we6
Q-score: 0.491
Gao S, Yao X, Chen J, Huang G, Fan X, Xue L, Li Z, Wu T, Zheng Y, Huang J, Jin X, Wang Y, Wang Z, Yu Y, Liu L, Pan X, Song C, Yan N
Cell (2023) 186 pp. 5363-5374.e16 [ DOI: doi:10.1016/j.cell.2023.10.007 Pubmed: 37972591 ]
- [(2r)-1-octadecanoyloxy-3-[oxidanyl-[(1r,2r,3s,4r,5r,6s)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phospho ryl]oxy-propan-2-yl] (8z)-icosa-5,8,11,14-tetraenoate (1 kDa, Ligand)
- Cav1.2 (Complex from Homo sapiens)
- Voltage-dependent l-type calcium channel subunit beta-3 (54 kDa, Protein from Homo sapiens)
- Voltage-dependent calcium channel subunit alpha-2/delta-1 (124 kDa, Protein from Homo sapiens)
- Calcium ion (40 Da, Ligand)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Cholesterol (386 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Voltage-dependent l-type calcium channel subunit alpha-1c (246 kDa, Protein from Homo sapiens)
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8we8
Q-score: 0.475
Gao S, Yao X, Chen J, Huang G, Fan X, Xue L, Li Z, Wu T, Zheng Y, Huang J, Jin X, Wang Y, Wang Z, Yu Y, Liu L, Pan X, Song C, Yan N
Cell (2023) 186 pp. 5363-5374.e16 [ DOI: doi:10.1016/j.cell.2023.10.007 Pubmed: 37972591 ]
- [(2r)-1-octadecanoyloxy-3-[oxidanyl-[(1r,2r,3s,4r,5r,6s)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phospho ryl]oxy-propan-2-yl] (8z)-icosa-5,8,11,14-tetraenoate (1 kDa, Ligand)
- Cav1.2 (Complex from Homo sapiens)
- Voltage-dependent l-type calcium channel subunit beta-3 (54 kDa, Protein from Homo sapiens)
- Voltage-dependent calcium channel subunit alpha-2/delta-1 (124 kDa, Protein from Homo sapiens)
- Calcium ion (40 Da, Ligand)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Amlodipine (408 Da, Ligand)
- Cholesterol (386 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Calciseptin (7 kDa, Protein from Dendroaspis polylepis polylepis)
- Voltage-dependent l-type calcium channel subunit alpha-1c (246 kDa, Protein from Homo sapiens)
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8we9
Q-score: 0.47
Gao S, Yao X, Chen J, Huang G, Fan X, Xue L, Li Z, Wu T, Zheng Y, Huang J, Jin X, Wang Y, Wang Z, Yu Y, Liu L, Pan X, Song C, Yan N
Cell (2023) 186 pp. 5363-5374.e16 [ DOI: doi:10.1016/j.cell.2023.10.007 Pubmed: 37972591 ]
- [(2r)-1-octadecanoyloxy-3-[oxidanyl-[(1r,2r,3s,4r,5r,6s)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phospho ryl]oxy-propan-2-yl] (8z)-icosa-5,8,11,14-tetraenoate (1 kDa, Ligand)
- Cav1.2 (Complex from Homo sapiens)
- Voltage-dependent l-type calcium channel subunit beta-3 (54 kDa, Protein from Homo sapiens)
- Voltage-dependent calcium channel subunit alpha-2/delta-1 (124 kDa, Protein from Homo sapiens)
- Calcium ion (40 Da, Ligand)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Cholesterol (386 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Voltage-dependent l-type calcium channel subunit alpha-1c (246 kDa, Protein from Homo sapiens)
Resolution: 2.87 Å
EM Method: Single-particle
Fitted PDBs: 8htu
Q-score: 0.55
Nat Plants (2023) 9 pp. 1347-1358 [ Pubmed: 37474782 DOI: doi:10.1038/s41477-023-01463-4 ]
- Chlorophyll a-b binding protein, chloroplastic (34 kDa, Protein from Physcomitrium patens)
- Photosystem i reaction center subunit ix (4 kDa, Protein from Physcomitrium patens)
- Photosystem i iron-sulfur center (8 kDa, Protein from Physcomitrium patens)
- Dodecyl-beta-d-maltoside (510 Da, Ligand)
- Chlorophyll a-b binding protein, chloroplastic (25 kDa, Protein from Physcomitrium patens)
- 1,2-distearoyl-monogalactosyl-diglyceride (787 Da, Ligand)
- Psi subunit v (23 kDa, Protein from Physcomitrium patens)
- Photosystem i reaction center subunit v, chloroplastic (16 kDa, Protein from Physcomitrium patens)
- Photosystem i reaction center subunit iii (26 kDa, Protein from Physcomitrium patens)
- Photosystem i subunit o (15 kDa, Protein from Physcomitrium patens)
- Photosystem i reaction center subunit viii (4 kDa, Protein from Physcomitrium patens)
- Photosystem i reaction center subunit vi, chloroplastic (14 kDa, Protein from Physcomitrium patens)
- (3r,3'r,6s)-4,5-didehydro-5,6-dihydro-beta,beta-carotene-3,3'-diol (568 Da, Ligand)
- Photosystem i from physcomitrium patens (Complex from Physcomitrium patens)
- Chlorophyll b (907 Da, Ligand)
- Water (18 Da, Ligand)
- Chlorophyll a-b binding protein, chloroplastic (28 kDa, Protein from Physcomitrium patens)
- Chlorophyll a-b binding protein, chloroplastic (33 kDa, Protein from Physcomitrium patens)
- (3s,5r,6s,3's,5'r,6's)-5,6,5',6'-diepoxy-5,6,5',6'- tetrahydro-beta,beta-carotene-3,3'-diol (600 Da, Ligand)
- Photosystem i p700 chlorophyll a apoprotein a1 (83 kDa, Protein from Physcomitrium patens)
- Chlorophyll a (893 Da, Ligand)
- Photosystem i reaction center subunit ii, chloroplastic (22 kDa, Protein from Physcomitrium patens)
- Photosystem i p700 chlorophyll a apoprotein a2 (82 kDa, Protein from Physcomitrium patens)
- Iron/sulfur cluster (351 Da, Ligand)
- Chlorophyll a-b binding protein, chloroplastic (28 kDa, Protein from Physcomitrium patens)
- Digalactosyl diacyl glycerol (dgdg) (949 Da, Ligand)
- Photosystem i reaction center subunit xii (3 kDa, Protein from Physcomitrium patens)
- Photosystem i reaction center subunit iv, chloroplastic (13 kDa, Protein from Physcomitrium patens)
- Phylloquinone (450 Da, Ligand)
- Photosystem i subunit x (13 kDa, Protein from Physcomitrium patens)
- Beta-carotene (536 Da, Ligand)
- (1r,3r)-6-{(3e,5e,7e,9e,11e,13e,15e,17e)-18-[(1s,4r,6r)-4-hydroxy-2,2,6-trimethyl-7-oxabicyclo[4.1.0]hept-1-yl]-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaenylidene}-1,5,5-trimethylcyclohexane-1,3-diol (600 Da, Ligand)
- 1,2-dipalmitoyl-phosphatidyl-glycerole (722 Da, Ligand)
- Chlorophyll a-b binding protein, chloroplastic (29 kDa, Protein from Physcomitrium patens)
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 8e57
Q-score: 0.534
Yao X, Gao S, Wang J, Li Z, Huang J, Wang Y, Wang Z, Chen J, Fan X, Wang W, Jin X, Pan X, Yu Y, Lagrutta A, Yan N
Cell (2022) 185 pp. 4801-4810.e13 [ Pubmed: 36417914 DOI: doi:10.1016/j.cell.2022.10.024 ]
- Voltage-dependent calcium channel subunit alpha-2/delta-1 (125 kDa, Protein from Oryctolagus cuniculus)
- Calcium ion (40 Da, Ligand)
- Voltage-dependent l-type calcium channel subunit alpha-1s (212 kDa, Protein from Oryctolagus cuniculus)
- (2-butyl-1-benzofuran-3-yl){4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl}methanone (645 Da, Ligand)
- Propan-2-yl (2s)-2-{[(s)-{[(2r,3s,4r,5r)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2h)-yl)-4-ethynyl-3-hydroxy-4-methyloxolan-2-yl]methoxy}(phenoxy)phosphoryl]amino}propanoate (non-preferred name) (535 Da, Ligand)
- Cav1.1 (Complex from Oryctolagus cuniculus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Voltage-dependent calcium channel gamma-1 subunit (25 kDa, Protein from Oryctolagus cuniculus)
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8e58
Q-score: 0.533
Yao X, Gao S, Wang J, Li Z, Huang J, Wang Y, Wang Z, Chen J, Fan X, Wang W, Jin X, Pan X, Yu Y, Lagrutta A, Yan N
Cell (2022) 185 pp. 4801-4810.e13 [ Pubmed: 36417914 DOI: doi:10.1016/j.cell.2022.10.024 ]
- Voltage-dependent calcium channel subunit alpha-2/delta-1 (125 kDa, Protein from Oryctolagus cuniculus)
- Calcium ion (40 Da, Ligand)
- Voltage-dependent l-type calcium channel subunit alpha-1s (212 kDa, Protein from Oryctolagus cuniculus)
- (2-butyl-1-benzofuran-3-yl){4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl}methanone (645 Da, Ligand)
- Propan-2-yl (2s)-2-{[(s)-{[(2r,3s,4r,5r)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2h)-yl)-4-ethynyl-3-hydroxy-4-methyloxolan-2-yl]methoxy}(phenoxy)phosphoryl]amino}propanoate (non-preferred name) (535 Da, Ligand)
- Cav1.1 (Complex from Oryctolagus cuniculus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Voltage-dependent calcium channel gamma-1 subunit (25 kDa, Protein from Oryctolagus cuniculus)
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 7w9p
Q-score: 0.456
Huang G, Liu D, Wang W, Wu Q, Chen J, Pan X, Shen H, Yan N
Cell Rep (2022) 39 pp. 110735-110735 [ Pubmed: 35476982 DOI: doi:10.1016/j.celrep.2022.110735 ]
- Sodium channel subunit beta-1 (24 kDa, Protein from Homo sapiens)
- [(3as,4r,10as)-2,6-diamino-10,10-dihydroxy-3a,4,9,10-tetrahydro-3h,8h-pyrrolo[1,2-c]purin-4-yl]methyl carbamate (299 Da, Ligand)
- Cholesterol hemisuccinate (486 Da, Ligand)
- (2s,3r,4e)-2-(acetylamino)-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate (421 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- O-[(r)-{[(2r)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-l-serine (792 Da, Ligand)
- Sodium channel subunit beta-2 (24 kDa, Protein from Homo sapiens)
- Sodium channel protein type 9 subunit alpha (231 kDa, Protein from Homo sapiens)
- Human voltage-gated sodium channel nav1.7 in complex with auxiliary beta subunits (279 MDa, Complex from Homo sapiens)
- 1-o-octadecyl-sn-glycero-3-phosphocholine (510 Da, Ligand)
- 1,2-dioleoyl-sn-glycero-3-phosphocholine (787 Da, Ligand)
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 7w9t
Q-score: 0.431
Huang G, Liu D, Wang W, Wu Q, Chen J, Pan X, Shen H, Yan N
Cell Rep (2022) 39 pp. 110735-110735 [ Pubmed: 35476982 DOI: doi:10.1016/j.celrep.2022.110735 ]
- 1,2-dioleoyl-sn-glycero-3-phosphocholine (787 Da, Ligand)
- Sodium channel protein type 9 subunit alpha (231 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Sodium channel subunit beta-2 (24 kDa, Protein from Homo sapiens)
- Human nav1.7 in complex with beta1, beta2 and huwentoxin (Complex from Homo sapiens)
- O-[(r)-{[(2r)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-l-serine (792 Da, Ligand)
- 1-o-octadecyl-sn-glycero-3-phosphocholine (510 Da, Ligand)
- [(3as,4r,10as)-2,6-diamino-10,10-dihydroxy-3a,4,9,10-tetrahydro-3h,8h-pyrrolo[1,2-c]purin-4-yl]methyl carbamate (299 Da, Ligand)
- (3beta,14beta,17beta,25r)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en (544 Da, Ligand)
- Cholesterol hemisuccinate (486 Da, Ligand)
- Sodium channel subunit beta-1 (24 kDa, Protein from Homo sapiens)
Left PSI in the cyclic electron transport supercomplex NDH-PSI from Arabidopsis
Resolution: 3.25 Å
EM Method: Single-particle
Fitted PDBs: 7wfd
Q-score: 0.526
Su X, Cao D, Pan X, Shi L, Liu Z, Dall'Osto L, Bassi R, Zhang X, Li M
Mol Plant (2022) 15 pp. 454-467 [ DOI: doi:10.1016/j.molp.2022.01.020 Pubmed: 35123031 ]
- Photosystem i reaction center subunit xi, chloroplastic (23 kDa, Protein from Arabidopsis thaliana)
- Photosystem i reaction center subunit iv a, chloroplastic (14 kDa, Protein from Arabidopsis thaliana)
- Photosystem i p700 chlorophyll a apoprotein a2 (82 kDa, Protein from Arabidopsis thaliana)
- Photosystem i chlorophyll a/b-binding protein 3-1, chloroplastic (29 kDa, Protein from Arabidopsis thaliana)
- 1,2-distearoyl-monogalactosyl-diglyceride (787 Da, Ligand)
- Photosystem i reaction center subunit viii (4 kDa, Protein from Arabidopsis thaliana)
- Photosystem i reaction center subunit ii-2, chloroplastic (22 kDa, Protein from Arabidopsis thaliana)
- Photosystem i reaction center subunit psak, chloroplastic (13 kDa, Protein from Arabidopsis thaliana)
- Cylic electron transfer supercomplex from arabidopsis (Complex from Arabidopsis thaliana)
- Photosystem i chlorophyll a/b-binding protein 6, chloroplastic (29 kDa, Protein from Arabidopsis thaliana)
- (3r,3'r,6s)-4,5-didehydro-5,6-dihydro-beta,beta-carotene-3,3'-diol (568 Da, Ligand)
- Photosystem i reaction center subunit v, chloroplastic (17 kDa, Protein from Arabidopsis thaliana)
- Photosystem i reaction center subunit ix (5 kDa, Protein from Arabidopsis thaliana)
- Chlorophyll b (907 Da, Ligand)
- (3s,5r,6s,3's,5'r,6's)-5,6,5',6'-diepoxy-5,6,5',6'- tetrahydro-beta,beta-carotene-3,3'-diol (600 Da, Ligand)
- Photosystem i p700 chlorophyll a apoprotein a1 (83 kDa, Protein from Arabidopsis thaliana)
- Chlorophyll a-b binding protein 4, chloroplastic (27 kDa, Protein from Arabidopsis thaliana)
- Chlorophyll a (893 Da, Ligand)
- Dodecyl-alpha-d-maltoside (510 Da, Ligand)
- Iron/sulfur cluster (351 Da, Ligand)
- Digalactosyl diacyl glycerol (dgdg) (949 Da, Ligand)
- Chlorophyll a-b binding protein 6, chloroplastic (26 kDa, Protein from Arabidopsis thaliana)
- Phylloquinone (450 Da, Ligand)
- Beta-carotene (536 Da, Ligand)
- 1,2-dipalmitoyl-phosphatidyl-glycerole (722 Da, Ligand)
- Photosystem i iron-sulfur center (9 kDa, Protein from Arabidopsis thaliana)
- Photosystem i reaction center subunit vi-2, chloroplastic (15 kDa, Protein from Arabidopsis thaliana)
- Photosystem i reaction center subunit iii, chloroplastic (24 kDa, Protein from Arabidopsis thaliana)
Right PSI in the cyclic electron transfer supercomplex NDH-PSI from Arabidopsis
Resolution: 3.25 Å
EM Method: Single-particle
Fitted PDBs: 7wfe
Q-score: 0.508
Su X, Cao D, Pan X, Shi L, Liu Z, Dall'Osto L, Bassi R, Zhang X, Li M
Mol Plant (2022) 15 pp. 454-467 [ DOI: doi:10.1016/j.molp.2022.01.020 Pubmed: 35123031 ]
- Photosystem i reaction center subunit xi, chloroplastic (23 kDa, Protein from Arabidopsis thaliana)
- Photosystem i reaction center subunit iv a, chloroplastic (14 kDa, Protein from Arabidopsis thaliana)
- Photosystem i p700 chlorophyll a apoprotein a2 (82 kDa, Protein from Arabidopsis thaliana)
- 1,2-di-o-acyl-3-o-[6-deoxy-6-sulfo-alpha-d-glucopyranosyl]-sn-glycerol (795 Da, Ligand)
- Photosystem i chlorophyll a/b-binding protein 3-1, chloroplastic (29 kDa, Protein from Arabidopsis thaliana)
- 1,2-distearoyl-monogalactosyl-diglyceride (787 Da, Ligand)
- Photosystem i reaction center subunit viii (4 kDa, Protein from Arabidopsis thaliana)
- Photosystem i chlorophyll a/b-binding protein 2, chloroplastic (27 kDa, Protein from Arabidopsis thaliana)
- Photosystem i reaction center subunit ii-2, chloroplastic (22 kDa, Protein from Arabidopsis thaliana)
- Photosystem i reaction center subunit psak, chloroplastic (13 kDa, Protein from Arabidopsis thaliana)
- (3r,3'r,6s)-4,5-didehydro-5,6-dihydro-beta,beta-carotene-3,3'-diol (568 Da, Ligand)
- Photosystem i reaction center subunit v, chloroplastic (17 kDa, Protein from Arabidopsis thaliana)
- Photosystem i chlorophyll a/b-binding protein 5, chloroplastic (27 kDa, Protein from Arabidopsis thaliana)
- Photosystem i reaction center subunit ix (5 kDa, Protein from Arabidopsis thaliana)
- Chlorophyll b (907 Da, Ligand)
- (3s,5r,6s,3's,5'r,6's)-5,6,5',6'-diepoxy-5,6,5',6'- tetrahydro-beta,beta-carotene-3,3'-diol (600 Da, Ligand)
- Photosystem i p700 chlorophyll a apoprotein a1 (83 kDa, Protein from Arabidopsis thaliana)
- Chlorophyll a (893 Da, Ligand)
- Dodecyl-alpha-d-maltoside (510 Da, Ligand)
- Psi complex in the ndh-psi supercomplex of arabidopsis (Complex from Arabidopsis thaliana)
- Iron/sulfur cluster (351 Da, Ligand)
- Digalactosyl diacyl glycerol (dgdg) (949 Da, Ligand)
- Chlorophyll a-b binding protein 6, chloroplastic (26 kDa, Protein from Arabidopsis thaliana)
- Phylloquinone (450 Da, Ligand)
- Beta-carotene (536 Da, Ligand)
- 1,2-dipalmitoyl-phosphatidyl-glycerole (722 Da, Ligand)
- Photosystem i iron-sulfur center (9 kDa, Protein from Arabidopsis thaliana)
- Photosystem i reaction center subunit vi-2, chloroplastic (15 kDa, Protein from Arabidopsis thaliana)
- Photosystem i reaction center subunit iii, chloroplastic (24 kDa, Protein from Arabidopsis thaliana)