SARS-CoV-2 RNA E-RTC complex with RMP-nsp9 and GMPPNP
Resolution: 2.72 Å
EM Method: Single-particle
Fitted PDBs: 8gwk
Q-score: 0.423
Yan L, Huang Y, Ge J, Liu Z, Lu P, Huang B, Gao S, Wang J, Tan L, Ye S, Yu F, Lan W, Xu S, Zhou F, Shi L, Guddat LW, Gao Y, Rao Z, Lou Z
Cell (2022) 185 pp. 4347-4360.e17 [ DOI: doi:10.1016/j.cell.2022.09.037 Pubmed: 36335936 ]
- Non-structural protein 9 (12 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Zinc ion (65 Da, Ligand)
- Rna-directed rna polymerase (106 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Non-structural protein 7 (9 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- E-rtc_rmp-nsp9_gmppnp (Complex from Severe acute respiratory syndrome coronavirus 2)
- Template (8 kDa, RNA from Severe acute respiratory syndrome coronavirus 2)
- Phosphoaminophosphonic acid-guanylate ester (522 Da, Ligand)
- Non-structural protein 8 (21 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Magnesium ion (24 Da, Ligand)
- [(2~{r},3~{s},4~{r},5~{r})-5-(4-azanylpyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-bis(oxidanyl)oxolan-2-yl]methyl dihydrogen phosphate (371 Da, Ligand)
- Helicase (66 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Water (18 Da, Ligand)
- Primer (8 kDa, RNA from Severe acute respiratory syndrome coronavirus 2)
Mycobacterium smegmatis Sdh1 in complex with UQ1
Resolution: 2.53 Å
EM Method: Single-particle
Fitted PDBs: 7d6v
Q-score: 0.636
Zhou X, Gao Y, Wang W, Yang X, Yang X, Liu F, Tang Y, Lam SM, Shui G, Yu L, Tian C, Guddat LW, Wang Q, Rao Z, Gong H
PNAS (2021) 118 [ Pubmed: 33876763 DOI: doi:10.1073/pnas.2022308118 ]
- Fe3-s4 cluster (295 Da, Ligand)
- Succinate dehydrogenase subunit a (70 kDa, Protein from Mycolicibacterium smegmatis)
- Fumarate reductase iron-sulfur subunit (28 kDa, Protein from Mycolicibacterium smegmatis)
- Ubiquinone-1 (250 Da, Ligand)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Mycobacterium smegmatis sdh1 in complex with uq1 (Complex from Mycolicibacterium smegmatis MC2 51)
- Succinate dehydrogenase (membrane anchor subunit) (32 kDa, Protein from Mycolicibacterium smegmatis)
- (1s)-2-{[(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-1-[(palmitoyloxy)methyl]ethyl stearate (720 Da, Ligand)
- Iron/sulfur cluster (351 Da, Ligand)
- Flavin-adenine dinucleotide (785 Da, Ligand)
Mycobacterium smegmatis Sdh1 complex in the apo form
Resolution: 2.88 Å
EM Method: Single-particle
Fitted PDBs: 7d6x
Q-score: 0.587
Zhou X, Gao Y, Wang W, Yang X, Yang X, Liu F, Tang Y, Lam SM, Shui G, Yu L, Tian C, Guddat LW, Wang Q, Rao Z, Gong H
PNAS (2021) 118 [ Pubmed: 33876763 DOI: doi:10.1073/pnas.2022308118 ]
- Fe3-s4 cluster (295 Da, Ligand)
- Succinate dehydrogenase subunit a (70 kDa, Protein from Mycolicibacterium smegmatis)
- Fumarate reductase iron-sulfur subunit (28 kDa, Protein from Mycolicibacterium smegmatis)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Succinate dehydrogenase (membrane anchor subunit) (32 kDa, Protein from Mycolicibacterium smegmatis)
- Mycobacterium smegmatis sdh1 complex in apo form (Complex from Mycolicibacterium smegmatis MC2 51)
- (1s)-2-{[(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-1-[(palmitoyloxy)methyl]ethyl stearate (720 Da, Ligand)
- Iron/sulfur cluster (351 Da, Ligand)
- Flavin-adenine dinucleotide (785 Da, Ligand)