CryoEM structure of human full-length alpha1beta3gamma2L GABA(A)R in complex with GABA and puerarin
Resolution: 2.4 Å
EM Method: Single-particle
Fitted PDBs: 9eqg
Q-score: 0.627
Lyu Q, Xue W, Liu R, Ma Q, Kasaragod VB, Sun S, Li Q, Chen Y, Yuan M, Yang Y, Zhang B, Nie A, Jia S, Shen C, Gao P, Rong W, Yu C, Bi Y, Zhang C, Nan F, Ning G, Rao Z, Yang X, Wang J, Wang W
Nature (2024) 634 pp. 936-943 [ Pubmed: 39261733 DOI: doi:10.1038/s41586-024-07929-5 ]
- Gamma-aminobutyric acid receptor subunit beta-3 (54 kDa, Protein from Homo sapiens)
- Hexane (86 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- 1,2-dilauroyl-sn-glycero-3-phosphate (535 Da, Ligand)
- Water (18 Da, Ligand)
- Palmitic acid (256 Da, Ligand)
- Gamma-amino-butanoic acid (103 Da, Ligand)
- Gamma-aminobutyric acid receptor subunit gamma-2 (56 kDa, Protein from Homo sapiens)
- [(2r)-1-octadecanoyloxy-3-[oxidanyl-[(1r,2r,3s,4r,5r,6s)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phospho ryl]oxy-propan-2-yl] (8z)-icosa-5,8,11,14-tetraenoate (1 kDa, Ligand)
- Hexadecane (226 Da, Ligand)
- Decane (142 Da, Ligand)
- (1r)-2-{[(s)-{[(2s)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9z)-octadec-9-enoate (749 Da, Ligand)
- Puerarin (416 Da, Ligand)
- Cryoem structure of human full-length alpha1beta3gamma2l gaba(a)r in complex with gaba and puerarin (250 kDa, Complex from Homo sapiens)
- Chloride ion (35 Da, Ligand)
- Gamma-aminobutyric acid receptor subunit alpha-1 (52 kDa, Protein from Homo sapiens)
Cryo-EM structure of human ABCC4
Resolution: 2.84 Å
EM Method: Single-particle
Fitted PDBs: 8xok
Q-score: 0.438
Zhu Y, Xing X, Wang F, Chen L, Zhong C, Lu X, Yu Z, Yang Y, Yao Y, Song Q, Han S, Liu Z, Zhang P
FEBS Lett (2024) 598 pp. 1967-1980 [ Pubmed: 38886124 DOI: doi:10.1002/1873-3468.14955 ]
- Apo human abcc4 (149 kDa, Cellular component from Homo sapiens)
- Atp-binding cassette sub-family c member 4 (149 kDa, Protein from Homo sapiens)
- Palmitic acid (256 Da, Ligand)
- 2-[2-[(1~{s},2~{s},4~{s},5'~{r},6~{r},7~{s},8~{r},9~{s},12~{s},13~{r},16~{s})-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-18-ene-6,2'-oxane]-16-yl]oxyethyl]propane-1,3-diol (516 Da, Ligand)
Bry-LHCII homotrimer of Bryopsis corticulans
Resolution: 2.55 Å
EM Method: Single-particle
Fitted PDBs: 8hlv
Q-score: 0.608
Li Z, Zhou C, Zhao S, Zhang J, Liu X, Sang M, Qin X, Yang Y, Han G, Kuang T, Shen JR, Wang W
Structure (2023) 31 pp. 1247- [ DOI: doi:10.1016/j.str.2023.08.001 Pubmed: 37633266 ]
- Siphonein (781 Da, Ligand)
- (1r,3r)-6-{(3e,5e,7e,9e,11e,13e,15e,17e)-18-[(1s,4r,6r)-4-hydroxy-2,2,6-trimethyl-7-oxabicyclo[4.1.0]hept-1-yl]-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaenylidene}-1,5,5-trimethylcyclohexane-1,3-diol (600 Da, Ligand)
- Siphonaxanthin (600 Da, Ligand)
- Chlorophyll b (907 Da, Ligand)
- Bryopsis corticulans chlorophyll a/b-type light-harvesting complex ii homotrimer (Complex from Bryopsis corticulans)
- 1,2-dipalmitoyl-phosphatidyl-glycerole (722 Da, Ligand)
- Chlorophyll a (893 Da, Ligand)
- Siphonaxanthin chlorophyll a/b binding light-harvesting complex ii, bry-lhcb1 (26 kDa, Protein from Bryopsis corticulans)
Bry-LHCII heterotrimer of Bryopsis corticulans
Resolution: 2.74 Å
EM Method: Single-particle
Fitted PDBs: 8hpd
Q-score: 0.571
Li Z, Zhou C, Zhao S, Zhang J, Liu X, Sang M, Qin X, Yang Y, Han G, Kuang T, Shen JR, Wang W
Structure (2023) 31 pp. 1247-1258.e3 [ DOI: doi:10.1016/j.str.2023.08.001 Pubmed: 37633266 ]
- Siphonaxanthin chlorophyll a/b binding light-harvesting complex ii, bry-lhcb2 (27 kDa, Protein from Bryopsis corticulans)
- Siphonein (781 Da, Ligand)
- (1r,3r)-6-{(3e,5e,7e,9e,11e,13e,15e,17e)-18-[(1s,4r,6r)-4-hydroxy-2,2,6-trimethyl-7-oxabicyclo[4.1.0]hept-1-yl]-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaenylidene}-1,5,5-trimethylcyclohexane-1,3-diol (600 Da, Ligand)
- Siphonaxanthin (600 Da, Ligand)
- Siphonaxanthin chlorophyll a/b binding light-harvesting complex ii, bry-lhcb1 (26 kDa, Protein from Bryopsis corticulans)
- Chlorophyll b (907 Da, Ligand)
- 1,2-dipalmitoyl-phosphatidyl-glycerole (722 Da, Ligand)
- Chlorophyll a (893 Da, Ligand)
- Siphonaxanthin chlorophyll a/b binding light-harvesting complex ii, bry-lhcb3 (27 kDa, Protein from Bryopsis corticulans)
- Bryopsis corticulans chlorophyll a/b-type light-harvesting complex ii heterotrimer (Complex from Bryopsis corticulans)
structure of a membrane-integrated glycosyltransferase with inhibitor
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 7xs6
Q-score: 0.572
Wu Y, Zhang M, Yang Y, Ding X, Yang P, Huang K, Hu X, Zhang M, Liu X, Yu H
Cell Discov (2022) 8 pp. 129-129 [ DOI: doi:10.1038/s41421-022-00495-y Pubmed: 36473834 ]
- Tetradecane (198 Da, Ligand)
- Membrane-integrated glycosyltransferase (Complex from Saccharomyces cerevisiae)
- Chitin synthase 1 (130 kDa, Protein from Saccharomyces cerevisiae)
- (2s)-{[(2s,3s,4s)-2-amino-4-hydroxy-4-(5-hydroxypyridin-2-yl)-3-methylbutanoyl]amino}[(2r,3s,4r,5r)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2h)-yl)-3,4-dihydroxyoxolan-2-yl]acetic acid (non-preferred name) (495 Da, Ligand)
- Heptane (100 Da, Ligand)
- (19r,22s)-25-amino-22-hydroxy-22-oxido-16-oxo-17,21,23-trioxa-22lambda~5~-phosphapentacosan-19-yl (9z)-hexadec-9-enoate (689 Da, Ligand)
- Dodecane (170 Da, Ligand)