Glutamate dehydrogenase in complex with GTP
Resolution: 3.47 Å
EM Method: Single-particle
Fitted PDBs: 3jd0
Q-score: 0.421
Borgnia MJ, Banerjee S, Merk A, Matthies D, Bartesaghi A, Rao P, Pierson J, Earl LA, Falconieri V, Subramaniam S, Milne JL
Mol Pharmacol (2016) 89 pp. 645-651 [ DOI: doi:10.1124/mol.116.103382 Pubmed: 27036132 ]
- [[(2r,3s,4r,5r)-5-(2-amino-6-oxo-3h-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate (1 kDa, Ligand from unidentified)
- L-glutamate:nad(p)+ oxidoreductase (deaminating) (56 kDa, Protein from Bos taurus)
- Binary complex of bovine glutamate dehydrogenase with gtp (339 kDa, Sample)
Glutamate dehydrogenase in complex with NADH and GTP, open conformation
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 3jd3
Q-score: 0.441
Borgnia MJ, Banerjee S, Merk A, Matthies D, Bartesaghi A, Rao P, Pierson J, Earl LA, Falconieri V, Subramaniam S, Milne JL
Mol Pharmacol (2016) 89 pp. 645-651 [ DOI: doi:10.1124/mol.116.103382 Pubmed: 27036132 ]
- [[(2r,3s,4r,5r)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2r,3s,4r,5r)-5-(3-carbamoyl-4h-pyridin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl hydrogen phosphate (1 kDa, Ligand from unidentified)
- Ternary complex of bovine glutamate dehydrogenase with gtp and nadh (347 kDa, Sample)
- [[(2r,3s,4r,5r)-5-(2-amino-6-oxo-3h-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate (1 kDa, Ligand from unidentified)
- L-glutamate:nad(p)+ oxidoreductase (deaminating) (56 kDa, Protein from Bos taurus)
Glutamate dehydrogenase in complex with NADH and GTP, closed conformation
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 3jd4
Q-score: 0.489
Borgnia MJ, Banerjee S, Merk A, Matthies D, Bartesaghi A, Rao P, Pierson J, Earl LA, Falconieri V, Subramaniam S, Milne JL
Mol Pharmacol (2016) 89 pp. 645-651 [ Pubmed: 27036132 DOI: doi:10.1124/mol.116.103382 ]
- L-glutamate:nad(p)+ oxidoreductase (deaminating) (56 kDa, Protein from Bos taurus)
- Ternary complex of bovine glutamate dehydrogenase with gtp and nadh (347 kDa, Sample)
- [[(2r,3s,4r,5r)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2r,3s,4r,5r)-5-(3-carbamoyl-4h-pyridin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl hydrogen phosphate (1 kDa, Ligand from unidentified)
- [[(2r,3s,4r,5r)-5-(2-amino-6-oxo-3h-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate (1 kDa, Ligand from unidentified)
Glutamate dehydrogenase in complex with NADH, closed conformation
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 3jd1
Q-score: 0.44
Borgnia MJ, Banerjee S, Merk A, Matthies D, Bartesaghi A, Rao P, Pierson J, Earl LA, Falconieri V, Subramaniam S, Milne JL
Mol Pharmacol (2016) 89 pp. 645-651 [ DOI: doi:10.1124/mol.116.103382 Pubmed: 27036132 ]
- [[(2r,3s,4r,5r)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2r,3s,4r,5r)-5-(3-carbamoyl-4h-pyridin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl hydrogen phosphate (1 kDa, Ligand from unidentified)
- Binary complex of bovine glutamate dehydrogenase with nadh (344 kDa, Sample)
- L-glutamate:nad(p)+ oxidoreductase (deaminating) (56 kDa, Protein from Bos taurus)
Glutamate dehydrogenase in complex with NADH, open conformation
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 3jd2
Q-score: 0.501
Borgnia MJ, Banerjee S, Merk A, Matthies D, Bartesaghi A, Rao P, Pierson J, Earl LA, Falconieri V, Subramaniam S, Milne JL
Mol Pharmacol (2016) 89 pp. 645-651 [ DOI: doi:10.1124/mol.116.103382 Pubmed: 27036132 ]
- [[(2r,3s,4r,5r)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2r,3s,4r,5r)-5-(3-carbamoyl-4h-pyridin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl hydrogen phosphate (1 kDa, Ligand from unidentified)
- Binary complex of bovine glutamate dehydrogenase with nadh (344 kDa, Sample)
- L-glutamate:nad(p)+ oxidoreductase (deaminating) (56 kDa, Protein from Bos taurus)
Density map of GluK2 desensitized state in complex with 2S,4R-4-methylglutamate
Resolution: 7.6 Å
EM Method: Single-particle
Fitted PDBs: 4uqq
Q-score: 0.132
Meyerson JR, Kumar J, Chittori S, Rao P, Pierson J, Bartesaghi A, Mayer ML, Subramaniam S
Nature (2014) 514 pp. 328-334 [ Pubmed: 25119039 DOI: doi:10.1038/NATURE13603 ]
- Gluk2 (400 kDa, Protein from Rattus norvegicus)
- 2s,4r-4-methylglutamate (Ligand from synthetic construct)
- Gluak2 with 2s,4r-4-methylglutamate (400 kDa, Sample)