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Streptomycin and Hygromycin B bound to the 30S body

Release date: July 26, 2023
Resolution: 2.08 Å
EM Method: Single-particle
Fitted PDBs: 8cai
Q-score: 0.698

Paternoga H, Crowe-McAuliffe C, Bock LV, Koller TO, Morici M, Beckert B, Myasnikov AG, Grubmuller H, Novacek J, Wilson DN

Nat Struct Mol Biol (2023) 30 pp. 1380-1392 [ Pubmed: 37550453 DOI: doi:10.1038/s41594-023-01047-y ]

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Streptomycin bound to the 30S body

Release date: July 26, 2023
Resolution: 1.79 Å
EM Method: Single-particle
Fitted PDBs: 8cgj
Q-score: 0.729

Paternoga H, Crowe-McAuliffe C, Bock LV, Koller TO, Morici M, Beckert B, Myasnikov AG, Grubmuller H, Novacek J, Wilson DN

Nat Struct Mol Biol (2023) 30 pp. 1380-1392 [ Pubmed: 37550453 DOI: doi:10.1038/s41594-023-01047-y ]

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Apramycin bound to the 30S body

Release date: July 26, 2023
Resolution: 2.12 Å
EM Method: Single-particle
Fitted PDBs: 8cgr
Q-score: 0.722

Paternoga H, Crowe-McAuliffe C, Bock LV, Koller TO, Morici M, Beckert B, Myasnikov AG, Grubmuller H, Novacek J, Wilson DN

Nat Struct Mol Biol (2023) 30 pp. 1380-1392 [ Pubmed: 37550453 DOI: doi:10.1038/s41594-023-01047-y ]

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Gentamicin bound to the 30S body

Release date: July 26, 2023
Resolution: 1.89 Å
EM Method: Single-particle
Fitted PDBs: 8cgu
Q-score: 0.76

Paternoga H, Crowe-McAuliffe C, Bock LV, Koller TO, Morici M, Beckert B, Myasnikov AG, Grubmuller H, Novacek J, Wilson DN

Nat Struct Mol Biol (2023) 30 pp. 1380-1392 [ Pubmed: 37550453 DOI: doi:10.1038/s41594-023-01047-y ]

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Kasugamycin bound to the 30S body

Release date: July 19, 2023
Resolution: 2.04 Å
EM Method: Single-particle
Fitted PDBs: 8cep
Q-score: 0.734

Paternoga H, Crowe-McAuliffe C, Bock LV, Koller TO, Morici M, Beckert B, Myasnikov AG, Grubmuller H, Novacek J, Wilson DN

Nat Struct Mol Biol (2023) 30 pp. 1380-1392 [ Pubmed: 37550453 DOI: doi:10.1038/s41594-023-01047-y ]

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Lincomycin and Avilamycin bound to the 50S subunit

Release date: July 19, 2023
Resolution: 1.64 Å
EM Method: Single-particle
Fitted PDBs: 8cgk
Q-score: 0.799

Paternoga H, Crowe-McAuliffe C, Bock LV, Koller TO, Morici M, Beckert B, Myasnikov AG, Grubmuller H, Novacek J, Wilson DN

Nat Struct Mol Biol (2023) 30 pp. 1380-1392 [ Pubmed: 37550453 DOI: doi:10.1038/s41594-023-01047-y ]

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Cryo-EM structure of the E.coli 70S ribosome in complex with the antibiotic Myxovalargin B.

Release date: Jan. 25, 2023
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8b7y
Q-score: 0.556

Koller TO, Scheid U, Kosel T, Herrmann J, Krug D, Boshoff HIM, Beckert B, Evans JC, Schlemmer J, Sloan B, Weiner DM, Via LE, Moosa A, Ioerger TR, Graf M, Zinshteyn B, Abdelshahid M, Nguyen F, Arenz S, Gille F, Siebke M, Seedorf T, Plettenburg O, Green R, Warnke AL, Ullrich J, Warrass R, Barry 3rd CE, Warner DF, Mizrahi V, Kirschning A, Wilson DN, Muller R

J Am Chem Soc (2023) 145 pp. 851-863 [ DOI: doi:10.1021/jacs.2c08816 Pubmed: 36603206 ]

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LsaA, an antibiotic resistance ABCF, in complex with 70S ribosome from Enterococcus faecalis

Release date: May 5, 2021
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 7nhk
Q-score: 0.519

Crowe-McAuliffe C, Murina V, Turnbull KJ, Kasari M, Mohamad M, Polte C, Takada H, Vaitkevicius K, Johansson J, Ignatova Z, Atkinson GC, O'Neill AJ, Hauryliuk V, Wilson DN

Nat Commun (2021) 12 pp. 3577-3577 [ DOI: doi:10.1038/s41467-021-23753-1 Pubmed: 34117249 ]

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VgaA-LC, an antibiotic resistance ABCF, in complex with 70S ribosome from Staphylococcus aureus

Release date: May 5, 2021
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7nhl
Q-score: 0.476

Crowe-McAuliffe C, Murina V, Turnbull KJ, Kasari M, Mohamad M, Polte C, Takada H, Vaitkevicius K, Johansson J, Ignatova Z, Atkinson GC, O'Neill AJ, Hauryliuk V, Wilson DN

Nat Commun (2021) 12 pp. 3577-3577 [ DOI: doi:10.1038/s41467-021-23753-1 Pubmed: 34117249 ]

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70S ribosome from Staphylococcus aureus

Release date: May 5, 2021
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7nhm
Q-score: 0.494

Crowe-McAuliffe C, Murina V, Turnbull KJ, Kasari M, Mohamad M, Polte C, Takada H, Vaitkevicius K, Johansson J, Ignatova Z, Atkinson GC, O'Neill AJ, Hauryliuk V, Wilson DN

Nat Commun (2021) 12 pp. 3577-3577 [ DOI: doi:10.1038/s41467-021-23753-1 Pubmed: 34117249 ]

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