human NaS1 intermediate state 1
Resolution: 3.04 Å
EM Method: Single-particle
Fitted PDBs: 8y5u
Q-score: 0.513
Sci Adv (2024) 10 pp. eado6778- [ DOI: doi:10.1126/sciadv.ado6778 Pubmed: 39576865 ]
- Solute carrier family 13 member 1 (66 kDa, Protein from Homo sapiens)
- Sodium ion (22 Da, Ligand)
- Sulfate ion (96 Da, Ligand)
- Membrane sodium anion transproter 1 (Complex from Homo sapiens)
human NaS1 intermediate state 2
Resolution: 2.73 Å
EM Method: Single-particle
Fitted PDBs: 8y5w
Q-score: 0.579
Chen X, Zhang Y, Yin J, Liu C, Xie M, Wang Y, Chen M, Zhang R, Yuan X, Li D, Chen X, Gao X, Cai G, Zhang S, Zhou B, Yang M
Sci Adv (2024) 10 pp. eado6778-eado6778 [ Pubmed: 39576865 DOI: doi:10.1126/sciadv.ado6778 ]
- Sodium ion (22 Da, Ligand)
- Sulfate ion (96 Da, Ligand)
- Membrane sodium anion transproter 2 (Complex from Homo sapiens)
- Solute carrier family 13 member 1 (66 kDa, Protein from Homo sapiens)
human NaS1 intermediate state 3
Resolution: 3.25 Å
EM Method: Single-particle
Fitted PDBs: 8y5x
Q-score: 0.484
Chen X, Zhang Y, Yin J, Liu C, Xie M, Wang Y, Chen M, Zhang R, Yuan X, Li D, Chen X, Gao X, Cai G, Zhang S, Zhou B, Yang M
Sci Adv (2024) 10 pp. eado6778-eado6778 [ DOI: doi:10.1126/sciadv.ado6778 Pubmed: 39576865 ]
- Membrane sodium anion transproter 3 (Cellular component from Homo sapiens)
- Sodium ion (22 Da, Ligand)
- Sulfate ion (96 Da, Ligand)
- Solute carrier family 13 member 1 (66 kDa, Protein from Homo sapiens)
Chen X, Zhang Y, Yin J, Liu C, Xie M, Wang Y, Chen M, Zhang R, Yuan X, Li D, Chen X, Gao X, Cai G, Zhang S, Zhou B, Yang M
Sci Adv (2024) 10 pp. eado6778-eado6778 [ DOI: doi:10.1126/sciadv.ado6778 Pubmed: 39576865 ]
- Solute carrier family 13 member 1 (66 kDa, Protein from Homo sapiens)
- Sulfate ion (96 Da, Ligand)
- Membrane sodium anion transproter out (Complex from Homo sapiens)
Chen X, Zhang Y, Yin J, Liu C, Xie M, Wang Y, Chen M, Zhang R, Yuan X, Li D, Chen X, Gao X, Cai G, Zhang S, Zhou B, Yang M
Sci Adv (2024) 10 pp. eado6778-eado6778 [ DOI: doi:10.1126/sciadv.ado6778 Pubmed: 39576865 ]
- Sodium ion (22 Da, Ligand)
- Solute carrier family 13 member 1 (66 kDa, Protein from Homo sapiens)
- Sulfate ion (96 Da, Ligand)
- Membrane sodium anion transproter in (Complex from Homo sapiens)
MutSbeta bound to compound CHDI-00898647 in the canonical DNA-mismatch bound form
Resolution: 3.12 Å
EM Method: Single-particle
Fitted PDBs: 8r7v
Q-score: 0.381
To Be Published
- Double stranded dna (Complex from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Dna_61bp_cag2_loop_fwd (20 kDa, DNA from Homo sapiens)
- Sulfate ion (96 Da, Ligand)
- Dna mismatch repair protein msh2 (104 kDa, Protein from Homo sapiens)
- Dna mismatch repair protein msh3 (127 kDa, Protein from Homo sapiens)
- Mutsbeta in complex with the mismatched dna and compound (Complex)
- Dna_61bp_complement_rev (18 kDa, DNA from Homo sapiens)
- Mutsbeta (Complex from Homo sapiens)
- ~{n}-[3-[[2-[[3-fluoranyl-4-(4-methylpiperazin-1-yl)phenyl]amino]-7~{h}-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]phenyl]prop-2-enamide (487 Da, Ligand)
Cryo-EM structure of the HIV-1 JR-FL IDL Env trimer in complex with PGT122 Fab
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 9ber
Q-score: 0.327
Zhang P, Gorman J, Tsybovsky Y, Lu M, Liu Q, Gopan V, Singh M, Lin Y, Miao H, Seo Y, Kwon A, Olia AS, Chuang GY, Geng H, Lai YT, Zhou T, Mascola JR, Mothes W, Kwong PD, Lusso P
Cell Rep (2024) 43 pp. 114518-114518 [ DOI: doi:10.1016/j.celrep.2024.114518 Pubmed: 39028623 ]
- Cryo-em structure of the hiv-1 jr-fl idl env trimer in complex with pgt122 fab (Complex from Human immunodeficiency virus 1)
- Envelope glycoprotein gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- Envelope glycoprotein gp120 (53 kDa, Protein from Human immunodeficiency virus 1)
- Pgt122 heavy chain (14 kDa, Protein from Homo sapiens)
- Pgt122 light chain (11 kDa, Protein from Homo sapiens)
- Sulfate ion (96 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Substrate Binding Plasticity Revealed by Cryo-EM Structures of SLC26A2
Nat Commun (2024) 15 pp. 3616-3616 [ Pubmed: 38684689 DOI: doi:10.1038/s41467-024-48028-3 ]
- Sulfate ion (96 Da, Ligand)
- Sulfate transporter (74 kDa, Protein from Homo sapiens)
- Slc26a2 with sulfate (Complex from Homo sapiens)
NaS1 with sulfate - IN/IN state
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8w6h
Q-score: 0.567
Chi X, Chen Y, Li Y, Dai L, Zhang Y, Shen Y, Chen Y, Shi T, Yang H, Wang Z, Yan R
Sci Adv (2024) 10 pp. eadl3685-eadl3685 [ DOI: doi:10.1126/sciadv.adl3685 Pubmed: 38552027 ]
- Sodium ion (22 Da, Ligand)
- Sulfate ion (96 Da, Ligand)
- Solute carrier family 13 member 1 (67 kDa, Protein from Homo sapiens)
- Dimer of nas1 with sulfate in in/in state (Complex from Homo sapiens)
- Cholesterol (386 Da, Ligand)
NaS1 with sulfate in IN/OUT state
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8w6n
Q-score: 0.536
Chi X, Chen Y, Li Y, Dai L, Zhang Y, Shen Y, Chen Y, Shi T, Yang H, Wang Z, Yan R
Sci Adv (2024) 10 pp. eadl3685-eadl3685 [ DOI: doi:10.1126/sciadv.adl3685 Pubmed: 38552027 ]
- Solute carrier family 13 member 1 (67 kDa, Protein from Homo sapiens)
- Sulfate ion (96 Da, Ligand)
- Sodium ion (22 Da, Ligand)
- Structure of nas1 in complex with sulfate (Complex from Homo sapiens)