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Cryo-EM structure of the cross-exon pre-B complex

Release date: May 22, 2024
Resolution: 9.6 Å
EM Method: Single-particle
Fitted PDBs: 8qxd
Q-score: 0.096

Zhang Z, Kumar V, Dybkov O, Will CL, Zhong J, Ludwig SEJ, Urlaub H, Kastner B, Stark H, Luhrmann R

Nature (2024) 630 pp. 1012-1019 [ DOI: doi:10.1038/s41586-024-07458-1 Pubmed: 38778104 ]

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Cryo-EM structure of the cross-exon B-like complex

Release date: May 22, 2024
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 8qzs
Q-score: 0.168

Zhang Z, Kumar V, Dybkov O, Will CL, Zhong J, Ludwig SEJ, Urlaub H, Kastner B, Stark H, Luhrmann R

Nature (2024) 630 pp. 1012-1019 [ DOI: doi:10.1038/s41586-024-07458-1 Pubmed: 38778104 ]

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Cryo-EM structure of the cross-exon pre-B+AMPPNP complex

Release date: May 22, 2024
Resolution: 6.1 Å
EM Method: Single-particle
Fitted PDBs: 8r08
Q-score: 0.133

Zhang Z, Kumar V, Dybkov O, Will CL, Zhong J, Ludwig SEJ, Urlaub H, Kastner B, Stark H, Luhrmann R

Nature (2024) 630 pp. 1012-1019 [ DOI: doi:10.1038/s41586-024-07458-1 Pubmed: 38778104 ]

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Cryo-EM structure of the cross-exon pre-B+5'ss+ATPgammaS complex

Release date: May 22, 2024
Resolution: 4.3 Å
EM Method: Single-particle
Fitted PDBs: 8r09
Q-score: 0.161

Zhang Z, Kumar V, Dybkov O, Will CL, Zhong J, Ludwig SEJ, Urlaub H, Kastner B, Stark H, Luhrmann R

Nature (2024) 630 pp. 1012-1019 [ DOI: doi:10.1038/s41586-024-07458-1 Pubmed: 38778104 ]

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Cryo-EM structure of the cross-exon pre-B+5'ss complex

Release date: May 22, 2024
Resolution: 5.8 Å
EM Method: Single-particle
Fitted PDBs: 8r0a
Q-score: 0.102

Zhang Z, Kumar V, Dybkov O, Will CL, Zhong J, Ludwig SEJ, Urlaub H, Kastner B, Stark H, Luhrmann R

Nature (2024) 630 pp. 1012-1019 [ DOI: doi:10.1038/s41586-024-07458-1 Pubmed: 38778104 ]

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Cryo-EM structure of the cross-exon pre-B+ATP complex

Release date: May 22, 2024
Resolution: 4.4 Å
EM Method: Single-particle
Fitted PDBs: 8r0b
Q-score: 0.148

Zhang Z, Kumar V, Dybkov O, Will CL, Zhong J, Ludwig SEJ, Urlaub H, Kastner B, Stark H, Luhrmann R

Nature (2024) 630 pp. 1012-1019 [ DOI: doi:10.1038/s41586-024-07458-1 Pubmed: 38778104 ]

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Cryo-EM structure of the cross-exon pre-B+5'ssLNG+ATPyS complex

Release date: May 22, 2024
Resolution: 6.9 Å
EM Method: Single-particle
Fitted PDBs: 8rm5
Q-score: 0.109

Zhang Z, Kumar V, Dybkov O, Will CL, Zhong J, Ludwig SEJ, Urlaub H, Kastner B, Stark H, Luhrmann R

Nature (2024) 630 pp. 1012-1019 [ DOI: doi:10.1038/s41586-024-07458-1 Pubmed: 38778104 ]

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Cryo-EM structure of a human spliceosomal B complex protomer

Release date: Jan. 24, 2024
Resolution: 5.29 Å
EM Method: Single-particle
Fitted PDBs: 8qo9
Q-score: 0.158

Zhang Z, Kumar V, Dybkov O, Will CL, Urlaub H, Stark H, Luhrmann R

EMBO J (2024) 43 pp. 1065-1088 [ Pubmed: 38383864 DOI: doi:10.1038/s44318-024-00052-1 ]

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Structural organization of a late activated human spliceosome (Baqr, core region)

Release date: May 10, 2023
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7qtt
Q-score: 0.384

Schmitzova J, Cretu C, Dienemann C, Urlaub H, Pena V

Nature (2023) 617 pp. 842-850 [ DOI: doi:10.1038/s41586-023-06049-w Pubmed: 37165190 ]

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Structure of a late-stage activated spliceosome (BAqr) arrested with a dominant-negative Aquarius mutant (state B complex).

Release date: May 10, 2023
Resolution: 5.9 Å
EM Method: Single-particle
Fitted PDBs: 8ch6
Q-score: 0.154

Schmitzova J, Cretu C, Dienemann C, Urlaub H, Pena V

Nature (2023) 617 pp. 842-850 [ DOI: doi:10.1038/s41586-023-06049-w Pubmed: 37165190 ]

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