E. coli 70S-TEC complex in delivery state
Resolution: 3.17 Å
EM Method: Single-particle
Fitted PDBs: 9gr1
Q-score: 0.421
Webster MW, Chauvier A, Rahil H, Graziadei A, Charles K, Miropolskaya N, Takacs M, Saint-Andre C, Rappsilber J, Walter NG, Weixlbaumer A
Science (2024) 386 pp. eado8476-eado8476 [ Pubmed: 39607923 DOI: doi:10.1126/science.ado8476 ]
- 50s ribosomal protein l35 (7 kDa, Protein from Escherichia coli BL21(DE3))
- Small ribosomal subunit protein us15 (10 kDa, Protein from Escherichia coli BL21(DE3))
- 50s ribosomal protein l30 (6 kDa, Protein from Escherichia coli BL21(DE3))
- Trna(fmet) p-site (24 kDa, RNA from Escherichia coli)
- Small ribosomal subunit protein us3 (26 kDa, Protein from Escherichia coli BL21(DE3))
- 50s ribosomal protein l2 (29 kDa, Protein from Escherichia coli BL21(DE3))
- 50s ribosomal protein l32 (6 kDa, Protein from Escherichia coli BL21(DE3))
- Small ribosomal subunit protein us5 (17 kDa, Protein from Escherichia coli BL21(DE3))
- Small ribosomal subunit protein us2 (26 kDa, Protein from Escherichia coli BL21(DE3))
- Small ribosomal subunit protein us11 (13 kDa, Protein from Escherichia coli BL21(DE3))
- 50s ribosomal protein l25 (10 kDa, Protein from Escherichia coli BL21(DE3))
- Potassium ion (39 Da, Ligand)
- 50s ribosomal protein l21 (11 kDa, Protein from Escherichia coli BL21(DE3))
- 50s ribosomal protein l24 (11 kDa, Protein from Escherichia coli BL21(DE3))
- 70s ribosome (Complex from Escherichia coli BL21(DE3))
- Zinc ion (65 Da, Ligand)
- Mrna in ribosome channel (5 kDa, RNA from synthetic construct)
- 30s ribosomal protein s19 (10 kDa, Protein from Escherichia coli BL21(DE3))
- Small ribosomal subunit protein us8 (14 kDa, Protein from Escherichia coli BL21(DE3))
- Small ribosomal subunit protein bs20 (9 kDa, Protein from Escherichia coli BL21(DE3))
- 50s ribosomal protein l19 (13 kDa, Protein from Escherichia coli BL21(DE3))
- Phenylalanine (165 Da, Ligand)
- Small ribosomal subunit protein us17 (9 kDa, Protein from Escherichia coli BL21(DE3))
- Phe-nh-trna(phe) a-site (24 kDa, RNA from Escherichia coli)
- 50s ribosomal protein l5 (20 kDa, Protein from Escherichia coli BL21(DE3))
- 50s ribosomal protein l27 (9 kDa, Protein from Escherichia coli BL21(DE3))
- 30s ribosomal protein s16 (9 kDa, Protein from Escherichia coli BL21(DE3))
- Small ribosomal subunit protein us14 (11 kDa, Protein from Escherichia coli BL21(DE3))
- 50s ribosomal protein l9 (15 kDa, Protein from Escherichia coli BL21(DE3))
- 50s ribosomal protein l13 (16 kDa, Protein from Escherichia coli BL21(DE3))
- Small ribosomal subunit protein us9 (14 kDa, Protein from Escherichia coli BL21(DE3))
- 16s ribosomal rna (499 kDa, RNA from Escherichia coli BL21(DE3))
- 50s ribosomal protein l4 (22 kDa, Protein from Escherichia coli BL21(DE3))
- 50s ribosomal protein l33 (6 kDa, Protein from Escherichia coli BL21(DE3))
- Small ribosomal subunit protein bs21 (8 kDa, Protein from Escherichia coli BL21(DE3))
- Small ribosomal subunit protein bs6, fully modified isoform (15 kDa, Protein from Escherichia coli BL21(DE3))
- Small ribosomal subunit protein us4 (23 kDa, Protein from Escherichia coli BL21(DE3))
- 50s ribosomal protein l15 (15 kDa, Protein from Escherichia coli BL21(DE3))
- 50s ribosomal protein l20 (13 kDa, Protein from Escherichia coli BL21(DE3))
- 50s ribosomal protein l36 (4 kDa, Protein from Escherichia coli BL21(DE3))
- Large ribosomal subunit protein ul3 (22 kDa, Protein from Escherichia coli BL21(DE3))
- Mrna in sd-asd duplex (3 kDa, RNA from synthetic construct)
- 50s ribosomal protein l34 (5 kDa, Protein from Escherichia coli BL21(DE3))
- Small ribosomal subunit protein us13 (13 kDa, Protein from Escherichia coli BL21(DE3))
- 50s ribosomal protein l6 (18 kDa, Protein from Escherichia coli BL21(DE3))
- 50s ribosomal protein l16 (15 kDa, Protein from Escherichia coli BL21(DE3))
- 50s ribosomal protein l28 (9 kDa, Protein from Escherichia coli BL21(DE3))
- Small ribosomal subunit protein us7 (20 kDa, Protein from Escherichia coli BL21(DE3))
- 50s ribosomal protein l23 (11 kDa, Protein from Escherichia coli BL21(DE3))
- 50s ribosomal protein l29 (7 kDa, Protein from Escherichia coli BL21(DE3))
- 50s ribosomal protein l17 (14 kDa, Protein from Escherichia coli BL21(DE3))
- Small ribosomal subunit protein us12 (13 kDa, Protein from Escherichia coli BL21(DE3))
- Small ribosomal subunit protein us10 (11 kDa, Protein from Escherichia coli BL21(DE3))
- 23s ribosomal rna (948 kDa, RNA from Escherichia coli BL21(DE3))
- 5s ribosomal rna (38 kDa, RNA from Escherichia coli BL21(DE3))
- 50s ribosomal protein l14 (13 kDa, Protein from Escherichia coli BL21(DE3))
- Small ribosomal subunit protein bs18 (9 kDa, Protein from Escherichia coli BL21(DE3))
- Magnesium ion (24 Da, Ligand)
- 50s ribosomal protein l22 (12 kDa, Protein from Escherichia coli BL21(DE3))
- 50s ribosomal protein l18 (12 kDa, Protein from Escherichia coli BL21(DE3))
E167K RF2 on E. coli 70S release complex with UAA
Resolution: 2.77 Å
EM Method: Single-particle
Fitted PDBs: 8qk7
Q-score: 0.568
Pundir S, Larsson DSD, Selmer M, Sanyal S
To Be Published
- Small ribosomal subunit protein us8 (14 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l17 (14 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l19 (13 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l14 (13 kDa, Protein from Escherichia coli)
- Ribosome release complex (2 MDa, Complex from Escherichia coli)
- Potassium ion (39 Da, Ligand)
- 50s ribosomal protein l15 (15 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l23 (11 kDa, Protein from Escherichia coli)
- Large ribosomal subunit protein ul4 (22 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l35 (7 kDa, Protein from Escherichia coli)
- Spermine (202 Da, Ligand)
- Small ribosomal subunit protein us15 (10 kDa, Protein from Escherichia coli)
- 23s rrna (941 kDa, RNA from Escherichia coli)
- Large ribosomal subunit protein ul2 (29 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l33 (6 kDa, Protein from Escherichia coli)
- Large ribosomal subunit protein ul6 (18 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l20 (13 kDa, Protein from Escherichia coli)
- Spermidine (145 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- 50s ribosomal protein l29 (7 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein us9 (14 kDa, Protein from Escherichia coli)
- 16s rrna (499 kDa, RNA from Escherichia coli)
- Small ribosomal subunit protein us5 (17 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l18 (12 kDa, Protein from Escherichia coli)
- Mrna (15 kDa, RNA from Escherichia coli)
- Trna(fmet) (24 kDa, RNA from Escherichia coli)
- Small ribosomal subunit protein us11 (13 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l21 (11 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein bs16 (9 kDa, Protein from Escherichia coli)
- Large ribosomal subunit protein bl9 (15 kDa, Protein from Escherichia coli)
- Large ribosomal subunit protein ul3 (22 kDa, Protein from Escherichia coli)
- Large ribosomal subunit protein ul16 (15 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l36 (4 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l27 (9 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein us19 (10 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein us2 (26 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein bs20 (9 kDa, Protein from Escherichia coli)
- Large ribosomal subunit protein ul13 (16 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l32 (6 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein bs21 (8 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein us10 (11 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein bs6, fully modified isoform (15 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein us4 (23 kDa, Protein from Escherichia coli)
- Large ribosomal subunit protein bl31a (7 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l22 (12 kDa, Protein from Escherichia coli)
- 5s rrna (38 kDa, RNA from Escherichia coli)
- 50s ribosomal protein l24 (11 kDa, Protein from Escherichia coli)
- 1,4-diaminobutane (88 Da, Ligand)
- Small ribosomal subunit protein us13 (13 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l30 (6 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein us17 (9 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein bs18 (9 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l28 (9 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein us3 (26 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l25 (10 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l34 (5 kDa, Protein from Escherichia coli)
- Large ribosomal subunit protein ul5 (20 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein us12 (13 kDa, Protein from Escherichia coli)
- Peptide chain release factor rf2 (41 kDa, Protein from Escherichia coli K-12)
- Magnesium ion (24 Da, Ligand)
- Small ribosomal subunit protein us14 (11 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein us7 (20 kDa, Protein from Escherichia coli)
- Large ribosomal subunit protein ul11 (14 kDa, Protein from Escherichia coli)
Structure of arbekacin bound Escherichia coli 70S ribosome
Majumdar S, Parajuli NP, Ge X, Emmerich A, Sanyal S
To Be Published
- Large ribosomal subunit protein ul15 (15 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein us19 (10 kDa, Protein from Escherichia coli)
- Large ribosomal subunit protein bl28 (9 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein bs18 (9 kDa, Protein from Escherichia coli)
- Large ribosomal subunit protein bl35 (7 kDa, Protein from Escherichia coli)
- Large ribosomal subunit protein ul4 (22 kDa, Protein from Escherichia coli)
- Large ribosomal subunit protein bl25 (10 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein us12 (13 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein us5 (17 kDa, Protein from Escherichia coli)
- Arbekacin (552 Da, Ligand)
- Small ribosomal subunit protein bs20 (9 kDa, Protein from Escherichia coli)
- Large ribosomal subunit protein ul30 (6 kDa, Protein from Escherichia coli)
- Large ribosomal subunit protein bl31a (7 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein us7 (20 kDa, Protein from Escherichia coli)
- Large ribosomal subunit protein bl17 (14 kDa, Protein from Escherichia coli)
- Large ribosomal subunit protein ul14 (13 kDa, Protein from Escherichia coli)
- 16s rrna (499 kDa, RNA from Escherichia coli)
- Small ribosomal subunit protein bs6, fully modified isoform (15 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein us3 (26 kDa, Protein from Escherichia coli)
- 5s rrna (38 kDa, RNA from Escherichia coli)
- Small ribosomal subunit protein us15 (10 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein us14 (11 kDa, Protein from Escherichia coli)
- Large ribosomal subunit protein ul23 (11 kDa, Protein from Escherichia coli)
- Large ribosomal subunit protein ul13 (16 kDa, Protein from Escherichia coli)
- Large ribosomal subunit protein bl32 (6 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein us9 (14 kDa, Protein from Escherichia coli)
- Large ribosomal subunit protein ul5 (20 kDa, Protein from Escherichia coli)
- Large ribosomal subunit protein bl21 (11 kDa, Protein from Escherichia coli)
- Large ribosomal subunit protein bl33 (6 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein us8 (14 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein us17 (9 kDa, Protein from Escherichia coli)
- Large ribosomal subunit protein bl34 (5 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein us11 (13 kDa, Protein from Escherichia coli)
- Large ribosomal subunit protein bl36a (4 kDa, Protein from Escherichia coli)
- Escherichia coli 70s ribosome bound to fret-trna mrna (Complex from Escherichia coli)
- Small ribosomal subunit protein us4 (23 kDa, Protein from Escherichia coli)
- Large ribosomal subunit protein ul29 (7 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein us13 (13 kDa, Protein from Escherichia coli)
- Large ribosomal subunit protein ul6 (18 kDa, Protein from Escherichia coli)
- Large ribosomal subunit protein ul18 (12 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein bs21 (8 kDa, Protein from Escherichia coli)
- Mrna (9 kDa, RNA from Escherichia coli)
- Large ribosomal subunit protein ul2 (29 kDa, Protein from Escherichia coli)
- Large ribosomal subunit protein bl19 (13 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l3 (22 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein bs16 (9 kDa, Protein from Escherichia coli)
- Trna-fmet (24 kDa, RNA from Escherichia coli)
- Small ribosomal subunit protein us2 (26 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l16 (15 kDa, Protein from Escherichia coli)
- Large ribosomal subunit protein ul24 (11 kDa, Protein from Escherichia coli)
- Large ribosomal subunit protein bl27 (9 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein us10 (11 kDa, Protein from Escherichia coli)
- 23s rrna (941 kDa, RNA from Escherichia coli)
- Large ribosomal subunit protein bl20 (13 kDa, Protein from Escherichia coli)
70S Escherichia coli ribosome with Paenilamicin B2 bound with A- and P-site tRNA.
Resolution: 2.2 Å
EM Method: Single-particle
Fitted PDBs: 8r6c
Q-score: 0.668
Koller TO, Berger MJ, Morici M, Paternoga H, Bulatov T, Di Stasi A, Dang T, Mainz A, Raulf K, Crowe-McAuliffe C, Scocchi M, Mardirossian M, Beckert B, Vazquez-Laslop N, Mankin A, Sussmuth RD, Wilson DN
bioRxiv (2024) [ DOI: doi:10.1101/2024.05.21.595107 Pubmed: 38826346 ]
- Small ribosomal subunit protein us9 (14 kDa, Protein from Escherichia coli BW25113)
- Large ribosomal subunit protein ul24 (11 kDa, Protein from Escherichia coli BW25113)
- Small ribosomal subunit protein us3 (26 kDa, Protein from Escherichia coli BW25113)
- Small ribosomal subunit protein us4 (23 kDa, Protein from Escherichia coli BW25113)
- Small ribosomal subunit protein us12 (13 kDa, Protein from Escherichia coli BW25113)
- 30s ribosomal protein s7 (20 kDa, Protein from Escherichia coli BW25113)
- Large ribosomal subunit protein bl31a (7 kDa, Protein from Escherichia coli BW25113)
- Large ribosomal subunit protein ul14 (13 kDa, Protein from Escherichia coli BW25113)
- 30s ribosomal protein s20 (9 kDa, Protein from Escherichia coli BW25113)
- Large ribosomal subunit protein ul4 (22 kDa, Protein from Escherichia coli BW25113)
- Small ribosomal subunit protein bs21 (8 kDa, Protein from Escherichia coli BW25113)
- Large ribosomal subunit protein bl32 (6 kDa, Protein from Escherichia coli BW25113)
- Isoeucine-trna (24 kDa, RNA from Escherichia coli BW25113)
- Large ribosomal subunit protein bl27 (9 kDa, Protein from Escherichia coli BW25113)
- Large ribosomal subunit protein ul22 (12 kDa, Protein from Escherichia coli BW25113)
- Large ribosomal subunit protein bl33 (6 kDa, Protein from Escherichia coli BW25113)
- Potassium ion (39 Da, Ligand)
- Paenilamicin b2 bound to the 70s escherichia coli ribosome (Complex)
- Small ribosomal subunit protein us15 (10 kDa, Protein from Escherichia coli BW25113)
- Large ribosomal subunit protein bl36a (4 kDa, Protein from Escherichia coli BW25113)
- 70s escherichia coli ribosome (Complex from Escherichia coli BW25113)
- Small ribosomal subunit protein us5 (17 kDa, Protein from Escherichia coli BW25113)
- 30s ribosomal protein s16 (9 kDa, Protein from Escherichia coli BW25113)
- Large ribosomal subunit protein bl9 (15 kDa, Protein from Escherichia coli BW25113)
- Large ribosomal subunit protein bl20 (13 kDa, Protein from Escherichia coli BW25113)
- N-formylmethionine trna (24 kDa, RNA from Escherichia coli BW25113)
- 50s ribosomal protein l25 (10 kDa, Protein from Escherichia coli BW25113)
- Water (18 Da, Ligand)
- Leucine-trna (27 kDa, RNA from Escherichia coli BW25113)
- Zinc ion (65 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Large ribosomal subunit protein ul3 (22 kDa, Protein from Escherichia coli BW25113)
- Small ribosomal subunit protein us13 (13 kDa, Protein from Escherichia coli BW25113)
- Large ribosomal subunit protein ul13 (16 kDa, Protein from Escherichia coli BW25113)
- Large ribosomal subunit protein ul30 (6 kDa, Protein from Escherichia coli BW25113)
- 50s ribosomal protein l15 (15 kDa, Protein from Escherichia coli BW25113)
- Mrna (3 kDa, RNA from Escherichia coli BW25113)
- Large ribosomal subunit protein ul16 (15 kDa, Protein from Escherichia coli BW25113)
- Large ribosomal subunit protein ul18 (12 kDa, Protein from Escherichia coli BW25113)
- Paenilamicin b2 (1 kDa, Protein from synthetic construct)
- Small ribosomal subunit protein us11 (13 kDa, Protein from Escherichia coli BW25113)
- 23s ribosomal rna (941 kDa, RNA from Escherichia coli BW25113)
- Large ribosomal subunit protein ul6 (18 kDa, Protein from Escherichia coli BW25113)
- Large ribosomal subunit protein ul5 (20 kDa, Protein from Escherichia coli BW25113)
- Large ribosomal subunit protein bl21 (11 kDa, Protein from Escherichia coli BW25113)
- 16s ribosomal rna (497 kDa, RNA from Escherichia coli BW25113)
- Paenilamicin b2 (Complex from Paenibacillus larvae)
- Small ribosomal subunit protein bs18 (9 kDa, Protein from Escherichia coli BW25113)
- 30s ribosomal protein s6, fully modified isoform (15 kDa, Protein from Escherichia coli BW25113)
- Large ribosomal subunit protein bl35 (7 kDa, Protein from Escherichia coli BW25113)
- 5s ribosomal rna (38 kDa, RNA from Escherichia coli BW25113)
- Large ribosomal subunit protein ul29 (7 kDa, Protein from Escherichia coli BW25113)
- Large ribosomal subunit protein bl19 (13 kDa, Protein from Escherichia coli BW25113)
- Large ribosomal subunit protein bl28 (9 kDa, Protein from Escherichia coli BW25113)
- Large ribosomal subunit protein ul2 (29 kDa, Protein from Escherichia coli BW25113)
- Small ribosomal subunit protein us19 (10 kDa, Protein from Escherichia coli BW25113)
- Large ribosomal subunit protein bl34 (5 kDa, Protein from Escherichia coli BW25113)
- Small ribosomal subunit protein us17 (9 kDa, Protein from Escherichia coli BW25113)
- Small ribosomal subunit protein us8 (14 kDa, Protein from Escherichia coli BW25113)
- Large ribosomal subunit protein ul23 (11 kDa, Protein from Escherichia coli BW25113)
- Large ribosomal subunit protein bl17 (14 kDa, Protein from Escherichia coli BW25113)
- 30s ribosomal protein s2 (26 kDa, Protein from Escherichia coli BW25113)
- Small ribosomal subunit protein us14 (11 kDa, Protein from Escherichia coli BW25113)
- Small ribosomal subunit protein us10 (11 kDa, Protein from Escherichia coli BW25113)
70S Escherichia coli ribosome with Paenilamicin B2 bound with hybrid A/P- and hybrid P/E-tRNA.
Resolution: 2.4 Å
EM Method: Single-particle
Fitted PDBs: 8r8m
Q-score: 0.634
Koller TO, Berger MJ, Morici M, Paternoga H, Bulatov T, Di Stasi A, Dang T, Mainz A, Raulf K, Crowe-McAuliffe C, Scocchi M, Mardirossian M, Beckert B, Vazquez-Laslop N, Mankin A, Sussmuth RD, Wilson DN
bioRxiv (2024) [ Pubmed: 38826346 DOI: doi:10.1101/2024.05.21.595107 ]
- Small ribosomal subunit protein us8 (14 kDa, Protein from Escherichia coli BW25113)
- Paenilamicin b2 (Complex from Paenibacillus larvae)
- Large ribosomal subunit protein bl17 (14 kDa, Protein from Escherichia coli BW25113)
- Small ribosomal subunit protein us14 (11 kDa, Protein from Escherichia coli BW25113)
- Small ribosomal subunit protein bs21 (8 kDa, Protein from Escherichia coli BW25113)
- Small ribosomal subunit protein us4 (23 kDa, Protein from Escherichia coli BW25113)
- Small ribosomal subunit protein us15 (10 kDa, Protein from Escherichia coli BW25113)
- Leucine-trna (27 kDa, RNA from Escherichia coli BW25113)
- 30s ribosomal protein s16 (9 kDa, Protein from Escherichia coli BW25113)
- 70s escherichia coli ribosome (Complex from Escherichia coli BW25113)
- Potassium ion (39 Da, Ligand)
- Large ribosomal subunit protein bl33 (6 kDa, Protein from Escherichia coli BW25113)
- Large ribosomal subunit protein ul23 (11 kDa, Protein from Escherichia coli BW25113)
- Large ribosomal subunit protein bl35 (7 kDa, Protein from Escherichia coli BW25113)
- Water (18 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Small ribosomal subunit protein us5 (17 kDa, Protein from Escherichia coli BW25113)
- Paenilamicin b2 bound to the 70s escherichia coli ribosome (Complex)
- Large ribosomal subunit protein ul5 (20 kDa, Protein from Escherichia coli BW25113)
- Small ribosomal subunit protein us9 (14 kDa, Protein from Escherichia coli BW25113)
- 30s ribosomal protein s20 (9 kDa, Protein from Escherichia coli BW25113)
- 30s ribosomal protein s6, fully modified isoform (15 kDa, Protein from Escherichia coli BW25113)
- Small ribosomal subunit protein us19 (10 kDa, Protein from Escherichia coli BW25113)
- Large ribosomal subunit protein bl20 (13 kDa, Protein from Escherichia coli BW25113)
- Large ribosomal subunit protein ul13 (16 kDa, Protein from Escherichia coli BW25113)
- Small ribosomal subunit protein bs18 (9 kDa, Protein from Escherichia coli BW25113)
- Large ribosomal subunit protein ul2 (29 kDa, Protein from Escherichia coli BW25113)
- Large ribosomal subunit protein bl31a (7 kDa, Protein from Escherichia coli BW25113)
- Small ribosomal subunit protein us10 (11 kDa, Protein from Escherichia coli BW25113)
- Large ribosomal subunit protein ul4 (22 kDa, Protein from Escherichia coli BW25113)
- Large ribosomal subunit protein bl28 (9 kDa, Protein from Escherichia coli BW25113)
- Small ribosomal subunit protein us17 (9 kDa, Protein from Escherichia coli BW25113)
- Large ribosomal subunit protein ul3 (22 kDa, Protein from Escherichia coli BW25113)
- Isoleucine-trna (24 kDa, RNA from Escherichia coli BW25113)
- Large ribosomal subunit protein bl19 (13 kDa, Protein from Escherichia coli BW25113)
- Large ribosomal subunit protein bl9 (15 kDa, Protein from Escherichia coli BW25113)
- 5s ribosomal rna (38 kDa, RNA from Escherichia coli BW25113)
- Mrna (3 kDa, RNA from Escherichia coli BW25113)
- 16s ribosomal rna (497 kDa, RNA from Escherichia coli BW25113)
- Large ribosomal subunit protein ul29 (7 kDa, Protein from Escherichia coli BW25113)
- Large ribosomal subunit protein ul30 (6 kDa, Protein from Escherichia coli BW25113)
- Large ribosomal subunit protein bl32 (6 kDa, Protein from Escherichia coli BW25113)
- Large ribosomal subunit protein ul24 (11 kDa, Protein from Escherichia coli BW25113)
- Paenilamicin b2 (1 kDa, Protein from synthetic construct)
- Large ribosomal subunit protein ul22 (12 kDa, Protein from Escherichia coli BW25113)
- Small ribosomal subunit protein us13 (13 kDa, Protein from Escherichia coli BW25113)
- Small ribosomal subunit protein us11 (13 kDa, Protein from Escherichia coli BW25113)
- Small ribosomal subunit protein us12 (13 kDa, Protein from Escherichia coli BW25113)
- Small ribosomal subunit protein us3 (26 kDa, Protein from Escherichia coli BW25113)
- 30s ribosomal protein s7 (20 kDa, Protein from Escherichia coli BW25113)
- Large ribosomal subunit protein ul6 (18 kDa, Protein from Escherichia coli BW25113)
- 30s ribosomal protein s2 (26 kDa, Protein from Escherichia coli BW25113)
- 50s ribosomal protein l15 (15 kDa, Protein from Escherichia coli BW25113)
- Large ribosomal subunit protein ul18 (12 kDa, Protein from Escherichia coli BW25113)
- Large ribosomal subunit protein bl27 (9 kDa, Protein from Escherichia coli BW25113)
- Large ribosomal subunit protein ul14 (13 kDa, Protein from Escherichia coli BW25113)
- Large ribosomal subunit protein bl34 (5 kDa, Protein from Escherichia coli BW25113)
- Large ribosomal subunit protein bl36a (4 kDa, Protein from Escherichia coli BW25113)
- Large ribosomal subunit protein ul16 (15 kDa, Protein from Escherichia coli BW25113)
- Magnesium ion (24 Da, Ligand)
- Large ribosomal subunit protein bl21 (11 kDa, Protein from Escherichia coli BW25113)
- 50s ribosomal protein l25 (10 kDa, Protein from Escherichia coli BW25113)
- 23s ribosomal rna (941 kDa, RNA from Escherichia coli BW25113)
Cryo-EM structure of the human 55S mitoribosome with Tigecycline
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8k2a
Q-score: 0.545
Li X, Wang M, Denk T, Buschauer R, Li Y, Beckmann R, Cheng J
Nat Commun (2024) 15 pp. 5481-5481 [ Pubmed: 38942792 DOI: doi:10.1038/s41467-024-49797-7 ]
- Small ribosomal subunit protein us14m (15 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ml40 (24 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ul23m (17 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein bl36m (11 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ml43 (23 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ul30m (18 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein bs6m (14 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ml54 (15 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein us17m (14 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein ms27 (47 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ml39 (38 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ml42 (16 kDa, Protein from Homo sapiens)
- 12s rrna (306 kDa, RNA from Homo sapiens)
- Small ribosomal subunit protein us12m (15 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ul29m (29 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein us2m (33 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ml63 (12 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ml62 (23 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein bl33m (7 kDa, Protein from Homo sapiens)
- Tigecycline (587 Da, Ligand)
- Large ribosomal subunit protein ml55 (15 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein ms25 (20 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein bl32m (21 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein bl35m (21 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein bs18m (15 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein ms39 (78 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ml48 (23 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ml37 (48 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein bl27m (16 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ml64 (25 kDa, Protein from Homo sapiens)
- 16s rrna (500 kDa, RNA from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Small ribosomal subunit protein ms23 (21 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ul2m (33 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ml51 (15 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein bl28m (30 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein bs1m (20 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein us5m (48 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l52, mitochondrial (13 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ml44 (37 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein us3m (19 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein bl9m (30 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ul14m (15 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein bl21m (22 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein ms26 (24 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein ms37 (13 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein us11m (20 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein us10m (23 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ml49 (19 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein bs16m (15 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ml53 (12 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein bl20m (17 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein bl17m (20 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ul24m (24 kDa, Protein from Homo sapiens)
- Val trna (22 kDa, RNA from Homo sapiens)
- Small ribosomal subunit protein ms22 (41 kDa, Protein from Homo sapiens)
- Mitochondrial ribosomal protein l18, isoform cra_b (20 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ml46 (31 kDa, Protein from Homo sapiens)
- 55s mitoribosome with tigecycline (Complex from Homo sapiens)
- Small ribosomal subunit protein ms31 (45 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ul10m (29 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Large ribosomal subunit protein ul11m (20 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein ms33 (12 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ml41 (15 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ml38 (44 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ml50 (18 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein ms34 (25 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ul13m (20 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ul3m (38 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein ms38 (22 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein us9m (45 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ml66 (22 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein us7m (28 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein bl19m (33 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein ms35 (36 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ul4m (34 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein us15m (29 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein ms29 (45 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ul16m (28 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l22, mitochondrial (24 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein bl34m (10 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ul15m (33 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein ms40 (29 kDa, Protein from Homo sapiens)
- Guanosine-5'-diphosphate (443 Da, Ligand)
- Large ribosomal subunit protein ml65 (50 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein bs21m (10 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ml45 (35 kDa, Protein from Homo sapiens)
Cryo-EM structure of the human 55S mitoribosome with 5um Tigecycline
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8xt0
Q-score: 0.434
Li X, Wang M, Denk T, Buschauer R, Li Y, Beckmann R, Cheng J
Nat Commun (2024) 15 pp. 5481-5481 [ Pubmed: 38942792 DOI: doi:10.1038/s41467-024-49797-7 ]
- Large ribosomal subunit protein ml65 (50 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ul24m (24 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein ms29 (45 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein bs21m (10 kDa, Protein from Homo sapiens)
- 16s rrna (500 kDa, RNA from Homo sapiens)
- Small ribosomal subunit protein ms37 (13 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ul3m (38 kDa, Protein from Homo sapiens)
- Tigecycline (587 Da, Ligand)
- Large ribosomal subunit protein ml53 (12 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Large ribosomal subunit protein ml62 (23 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein us9m (45 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein bs1m (20 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ul10m (29 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein bs18m (15 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ml42 (16 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein bl17m (20 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein bl34m (10 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein ms35 (36 kDa, Protein from Homo sapiens)
- 12s rrna (306 kDa, RNA from Homo sapiens)
- Small ribosomal subunit protein us7m (28 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein bl20m (17 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein ms38 (22 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein bl19m (33 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ml41 (15 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ml43 (23 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein ms26 (24 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ml37 (48 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ml38 (44 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ml48 (23 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein ms23 (21 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein bl35m (21 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l52, mitochondrial (13 kDa, Protein from Homo sapiens)
- Val trna (22 kDa, RNA from Homo sapiens)
- Large ribosomal subunit protein bl9m (30 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ml64 (25 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein ms31 (45 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ml54 (15 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ml55 (15 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein ms22 (41 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein us11m (20 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ml46 (31 kDa, Protein from Homo sapiens)
- Guanosine-5'-diphosphate (443 Da, Ligand)
- Large ribosomal subunit protein ul23m (17 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein ms40 (29 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ml51 (15 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l22, mitochondrial (24 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ul16m (28 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ml63 (12 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein us2m (33 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ul30m (18 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein ms33 (12 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein us15m (29 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ul14m (15 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein bs16m (15 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ml49 (19 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein bl27m (16 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Small ribosomal subunit protein us3m (19 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ul29m (29 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein us5m (48 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein bl32m (21 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ml66 (22 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein bl36m (11 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ul13m (20 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein ms34 (25 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein us17m (14 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein bl33m (7 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ul2m (33 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein bl28m (30 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein us14m (15 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ml50 (18 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ul15m (33 kDa, Protein from Homo sapiens)
- 55s ribosome with tigecycline (Complex from Homo sapiens)
- Small ribosomal subunit protein ms39 (78 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein bs6m (14 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein us12m (15 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ml40 (24 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ml45 (35 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ul11m (20 kDa, Protein from Homo sapiens)
- Mitochondrial ribosomal protein l18, isoform cra_b (20 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein us10m (23 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ul4m (34 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein bl21m (22 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ml44 (37 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein ms25 (20 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein ms27 (47 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ml39 (38 kDa, Protein from Homo sapiens)
Cryo-EM structure of the human 55S mitoribosome with 10uM Tigecycline
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 8xt2
Q-score: 0.415
Li X, Wang M, Denk T, Buschauer R, Li Y, Beckmann R, Cheng J
Nat Commun (2024) 15 pp. 5481-5481 [ Pubmed: 38942792 DOI: doi:10.1038/s41467-024-49797-7 ]
- Large ribosomal subunit protein ml65 (50 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ul24m (24 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein ms29 (45 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein bs21m (10 kDa, Protein from Homo sapiens)
- 16s rrna (500 kDa, RNA from Homo sapiens)
- Small ribosomal subunit protein ms37 (13 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ul3m (38 kDa, Protein from Homo sapiens)
- Tigecycline (587 Da, Ligand)
- Large ribosomal subunit protein ml53 (12 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Large ribosomal subunit protein ml62 (23 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein us9m (45 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein bs1m (20 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ul10m (29 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein bs18m (15 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ml42 (16 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein bl17m (20 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein bl34m (10 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein ms35 (36 kDa, Protein from Homo sapiens)
- 12s rrna (306 kDa, RNA from Homo sapiens)
- Small ribosomal subunit protein us7m (28 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein bl20m (17 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein ms38 (22 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein bl19m (33 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ml41 (15 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ml43 (23 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein ms26 (24 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ml37 (48 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ml38 (44 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ml48 (23 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein ms23 (21 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein bl35m (21 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l52, mitochondrial (13 kDa, Protein from Homo sapiens)
- Val trna (22 kDa, RNA from Homo sapiens)
- Large ribosomal subunit protein bl9m (30 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ml64 (25 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein ms31 (45 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ml54 (15 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ml55 (15 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein ms22 (41 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein us11m (20 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ml46 (31 kDa, Protein from Homo sapiens)
- Guanosine-5'-diphosphate (443 Da, Ligand)
- Large ribosomal subunit protein ul23m (17 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein ms40 (29 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ml51 (15 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l22, mitochondrial (24 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ul16m (28 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ml63 (12 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein us2m (33 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ul30m (18 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein ms33 (12 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein us15m (29 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ul14m (15 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein bs16m (15 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ml49 (19 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein bl27m (16 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Small ribosomal subunit protein us3m (19 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ul29m (29 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein us5m (48 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein bl32m (21 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ml66 (22 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein bl36m (11 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ul13m (20 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein ms34 (25 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein us17m (14 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein bl33m (7 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ul2m (33 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein bl28m (30 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein us14m (15 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ml50 (18 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ul15m (33 kDa, Protein from Homo sapiens)
- 55s ribosome with tigecycline (Complex from Homo sapiens)
- Small ribosomal subunit protein ms39 (78 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein bs6m (14 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein us12m (15 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ml40 (24 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ml45 (35 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ul11m (20 kDa, Protein from Homo sapiens)
- Mitochondrial ribosomal protein l18, isoform cra_b (20 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein us10m (23 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ul4m (34 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein bl21m (22 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ml44 (37 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein ms25 (20 kDa, Protein from Homo sapiens)
- Small ribosomal subunit protein ms27 (47 kDa, Protein from Homo sapiens)
- Large ribosomal subunit protein ml39 (38 kDa, Protein from Homo sapiens)
70S Escherichia coli ribosome with P-site initiatior tRNA.
Resolution: 2.4 Å
EM Method: Single-particle
Fitted PDBs: 9fbv
Q-score: 0.643
Koller TO, Berger MJ, Morici M, Paternoga H, Bulatov T, Di Stasi A, Dang T, Mainz A, Raulf K, Crowe-McAuliffe C, Scocchi M, Mardirossian M, Beckert B, Vazquez-Laslop N, Mankin A, Sussmuth RD, Wilson DN
bioRxiv (2024) [ Pubmed: 38826346 DOI: doi:10.1101/2024.05.21.595107 ]
- Small ribosomal subunit protein us8 (14 kDa, Protein from Escherichia coli BW25113)
- Large ribosomal subunit protein bl17 (14 kDa, Protein from Escherichia coli BW25113)
- Small ribosomal subunit protein bs21 (8 kDa, Protein from Escherichia coli BW25113)
- Small ribosomal subunit protein us14 (11 kDa, Protein from Escherichia coli BW25113)
- Small ribosomal subunit protein us4 (23 kDa, Protein from Escherichia coli BW25113)
- Small ribosomal subunit protein us15 (10 kDa, Protein from Escherichia coli BW25113)
- Fmet-trna (24 kDa, RNA from Escherichia coli BW25113)
- 30s ribosomal protein s16 (9 kDa, Protein from Escherichia coli BW25113)
- Potassium ion (39 Da, Ligand)
- Large ribosomal subunit protein bl33 (6 kDa, Protein from Escherichia coli BW25113)
- Large ribosomal subunit protein ul23 (11 kDa, Protein from Escherichia coli BW25113)
- Large ribosomal subunit protein bl35 (7 kDa, Protein from Escherichia coli BW25113)
- Water (18 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Small ribosomal subunit protein us5 (17 kDa, Protein from Escherichia coli BW25113)
- Large ribosomal subunit protein ul5 (20 kDa, Protein from Escherichia coli BW25113)
- 30s ribosomal protein s20 (9 kDa, Protein from Escherichia coli BW25113)
- Messenger rna (935 Da, RNA from Escherichia coli BW25113)
- Small ribosomal subunit protein us9 (14 kDa, Protein from Escherichia coli BW25113)
- 30s ribosomal protein s6, fully modified isoform (15 kDa, Protein from Escherichia coli BW25113)
- Small ribosomal subunit protein us19 (10 kDa, Protein from Escherichia coli BW25113)
- Large ribosomal subunit protein bl20 (13 kDa, Protein from Escherichia coli BW25113)
- Large ribosomal subunit protein ul13 (16 kDa, Protein from Escherichia coli BW25113)
- Small ribosomal subunit protein bs18 (9 kDa, Protein from Escherichia coli BW25113)
- Large ribosomal subunit protein ul2 (29 kDa, Protein from Escherichia coli BW25113)
- Escherichia coli 70s initiation complex with p-site initiator trna fmet (Complex from Escherichia coli BW25113)
- Large ribosomal subunit protein bl31a (7 kDa, Protein from Escherichia coli BW25113)
- Small ribosomal subunit protein us10 (11 kDa, Protein from Escherichia coli BW25113)
- Large ribosomal subunit protein ul4 (22 kDa, Protein from Escherichia coli BW25113)
- Large ribosomal subunit protein bl28 (9 kDa, Protein from Escherichia coli BW25113)
- Small ribosomal subunit protein us17 (9 kDa, Protein from Escherichia coli BW25113)
- Large ribosomal subunit protein ul3 (22 kDa, Protein from Escherichia coli BW25113)
- Large ribosomal subunit protein bl19 (13 kDa, Protein from Escherichia coli BW25113)
- Large ribosomal subunit protein bl9 (15 kDa, Protein from Escherichia coli BW25113)
- 5s ribosomal rna (38 kDa, RNA from Escherichia coli BW25113)
- 16s ribosomal rna (497 kDa, RNA from Escherichia coli BW25113)
- Large ribosomal subunit protein ul29 (7 kDa, Protein from Escherichia coli BW25113)
- Large ribosomal subunit protein ul30 (6 kDa, Protein from Escherichia coli BW25113)
- Large ribosomal subunit protein bl32 (6 kDa, Protein from Escherichia coli BW25113)
- Large ribosomal subunit protein ul24 (11 kDa, Protein from Escherichia coli BW25113)
- Large ribosomal subunit protein ul22 (12 kDa, Protein from Escherichia coli BW25113)
- Small ribosomal subunit protein us13 (13 kDa, Protein from Escherichia coli BW25113)
- Small ribosomal subunit protein us11 (13 kDa, Protein from Escherichia coli BW25113)
- Small ribosomal subunit protein us12 (13 kDa, Protein from Escherichia coli BW25113)
- Small ribosomal subunit protein us3 (26 kDa, Protein from Escherichia coli BW25113)
- 30s ribosomal protein s7 (20 kDa, Protein from Escherichia coli BW25113)
- Large ribosomal subunit protein ul6 (18 kDa, Protein from Escherichia coli BW25113)
- 30s ribosomal protein s2 (26 kDa, Protein from Escherichia coli BW25113)
- 50s ribosomal protein l15 (15 kDa, Protein from Escherichia coli BW25113)
- Large ribosomal subunit protein ul18 (12 kDa, Protein from Escherichia coli BW25113)
- Large ribosomal subunit protein bl27 (9 kDa, Protein from Escherichia coli BW25113)
- Large ribosomal subunit protein ul14 (13 kDa, Protein from Escherichia coli BW25113)
- Large ribosomal subunit protein bl34 (5 kDa, Protein from Escherichia coli BW25113)
- Large ribosomal subunit protein bl36a (4 kDa, Protein from Escherichia coli BW25113)
- Large ribosomal subunit protein ul16 (15 kDa, Protein from Escherichia coli BW25113)
- Magnesium ion (24 Da, Ligand)
- Large ribosomal subunit protein bl21 (11 kDa, Protein from Escherichia coli BW25113)
- 50s ribosomal protein l25 (10 kDa, Protein from Escherichia coli BW25113)
- 23s ribosomal rna (941 kDa, RNA from Escherichia coli BW25113)
E167K RF2 on E. coli 70S release complex with UGG (Structure I)
Pundir S, Larsson DSD, Selmer M, Sanyal S
To Be Published
- Small ribosomal subunit protein us8 (14 kDa, Protein from Escherichia coli)
- Magnesium ion (24 Da, Ligand)
- 50s ribosomal protein l17 (14 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l19 (13 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l14 (13 kDa, Protein from Escherichia coli)
- Ribosome release complex (2 MDa, Complex from Escherichia coli)
- 50s ribosomal protein l6 (18 kDa, Protein from Escherichia coli)
- Potassium ion (39 Da, Ligand)
- 50s ribosomal protein l15 (15 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l23 (11 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l35 (7 kDa, Protein from Escherichia coli)
- Spermine (202 Da, Ligand)
- Small ribosomal subunit protein us15 (10 kDa, Protein from Escherichia coli)
- 23s rrna (941 kDa, RNA from Escherichia coli)
- Zinc ion (65 Da, Ligand)
- 50s ribosomal protein l33 (6 kDa, Protein from Escherichia coli)
- Spermidine (145 Da, Ligand)
- 50s ribosomal protein l20 (13 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l3 (22 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l5 (20 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l29 (7 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l11 (14 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l2 (29 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein us9 (14 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l13 (16 kDa, Protein from Escherichia coli)
- 16s rrna (499 kDa, RNA from Escherichia coli)
- 50s ribosomal protein l4 (22 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein us5 (17 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l18 (12 kDa, Protein from Escherichia coli)
- Trna(fmet) (24 kDa, RNA from Escherichia coli)
- Small ribosomal subunit protein us11 (13 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l21 (11 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein bs16 (9 kDa, Protein from Escherichia coli)
- Mrna (15 kDa, RNA from Escherichia coli)
- 30s ribosomal protein s6 (15 kDa, Protein from Escherichia coli)
- Large ribosomal subunit protein ul16 (15 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l36 (4 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l27 (9 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein us19 (10 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein us2 (26 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein bs20 (9 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l32 (6 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein bs21 (8 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein us10 (11 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein us4 (23 kDa, Protein from Escherichia coli)
- Large ribosomal subunit protein bl31a (7 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l22 (12 kDa, Protein from Escherichia coli)
- 5s rrna (38 kDa, RNA from Escherichia coli)
- 50s ribosomal protein l24 (11 kDa, Protein from Escherichia coli)
- 1,4-diaminobutane (88 Da, Ligand)
- Small ribosomal subunit protein us13 (13 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l30 (6 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein us17 (9 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein bs18 (9 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s7 (20 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein us3 (26 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l28 (9 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l25 (10 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l34 (5 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein us12 (13 kDa, Protein from Escherichia coli)
- Peptide chain release factor rf2 (41 kDa, Protein from Escherichia coli K-12)
- 50s ribosomal protein l9 (15 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein us14 (11 kDa, Protein from Escherichia coli)