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EMBL

was set up in 1974 as Europe’s flagship laboratory for the life sciences – an intergovernmental organisation with more than 80 independent research groups covering the spectrum of molecular biology:

Research:

perform basic research in molecular biology

Services:

offer vital services to scientists in the member states

Training

scientists, students and visitors at all levels

Transfer

and development of technology

Develop

new instruments and methods

Integrating

life science research in Europe

More about EMBL

Six sites

represent EMBL in Europe.

Barcelona

Tissue biology and disease modelling

Grenoble

Structural biology

Hamburg

Structural biology

Heidelberg

Main laboratory

Hinxton

EMBL-EBI: European Bioinformatics Institute

Rome

Epigenetics and neurobiology

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sample_name:"TRiC/CCT" AND xref_links:"chebi" AND author_name:"S"

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EMD-35122

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Human TRiC-PhLP2A complex in the closed state

Release date: Jan. 31, 2024
Resolution: 3.24 Å
EM Method: Single-particle
Fitted PDBs: 8i1u
Q-score: 0.506

Park J, Kim H, Gestaut D, Lim S, Opoku-Nsiah KA, Leitner A, Frydman J, Roh SH

Nat Commun (2024) 15 pp. 1007-1007 [ Pubmed: 38307855 DOI: doi:10.1038/s41467-024-45242-x ]

Sample:

Magnesium ion (24 Da, Ligand)
T-complex protein 1 subunit beta (57 kDa, Protein from Homo sapiens)
T-complex protein 1 subunit eta (59 kDa, Protein from Homo sapiens)
Adenosine-5'-diphosphate (427 Da, Ligand)
Phosducin-like protein 3 (27 kDa, Protein from Homo sapiens)
T-complex protein 1 subunit gamma (60 kDa, Protein from Homo sapiens)
T-complex protein 1 subunit epsilon (59 kDa, Protein from Homo sapiens)
T-complex protein 1 subunit alpha (60 kDa, Protein from Homo sapiens)
Aluminum fluoride (83 Da, Ligand)
T-complex protein 1 subunit theta (59 kDa, Protein from Homo sapiens)
Human tric/cct complex (Complex from Homo sapiens)
Complex of tric/cct-phlp2a treated with atp-alfx (1 MDa, Complex from Homo sapiens)
T-complex protein 1 subunit delta (57 kDa, Protein from Homo sapiens)
T-complex protein 1 subunit zeta (58 kDa, Protein from Homo sapiens)
Phlp2a (pdcl3) (Complex)

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EMD-35199

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The focused refinement of CCT3-PhLP2A from TRiC-PhLP2A complex in the open state

Release date: Jan. 31, 2024
Resolution: 3.82 Å
EM Method: Single-particle
Fitted PDBs: 8i6j
Q-score: 0.404

Park J, Kim H, Gestaut D, Lim S, Opoku-Nsiah KA, Leitner A, Frydman J, Roh SH

Nat Commun (2024) 15 pp. 1007-1007 [ Pubmed: 38307855 DOI: doi:10.1038/s41467-024-45242-x ]

Sample:

Tric/cct (Complex)
Adenosine-5'-diphosphate (427 Da, Ligand)
Phlp2a (pdcl3) (Complex from Homo sapiens)
Phosducin-like protein 3 (27 kDa, Protein from Homo sapiens)
T-complex protein 1 subunit gamma (60 kDa, Protein from Homo sapiens)
Complex of tric/cct and phlp2a (1 MDa, Complex from Homo sapiens)

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EMD-35284

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Human TRiC-PhLP2A complex in the open state

Release date: Jan. 17, 2024
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8i9u
Q-score: 0.286

Park J, Kim H, Gestaut D, Lim S, Opoku-Nsiah KA, Leitner A, Frydman J, Roh SH

Nat Commun (2024) 15 pp. 1007-1007 [ Pubmed: 38307855 DOI: doi:10.1038/s41467-024-45242-x ]

Sample:

T-complex protein 1 subunit beta (57 kDa, Protein from Homo sapiens)
T-complex protein 1 subunit eta (59 kDa, Protein from Homo sapiens)
Phlp2a (pdcl3) in human tric/cct complex (Complex from Homo sapiens)
Adenosine-5'-diphosphate (427 Da, Ligand)
Phosducin-like protein 3 (27 kDa, Protein from Homo sapiens)
T-complex protein 1 subunit gamma (60 kDa, Protein from Homo sapiens)
T-complex protein 1 subunit epsilon (59 kDa, Protein from Homo sapiens)
T-complex protein 1 subunit alpha (60 kDa, Protein from Homo sapiens)
T-complex protein 1 subunit theta (59 kDa, Protein from Homo sapiens)
Human tric/cct complex (Complex from Homo sapiens)
T-complex protein 1 subunit delta (57 kDa, Protein from Homo sapiens)
T-complex protein 1 subunit zeta (58 kDa, Protein from Homo sapiens)
Complex of human tric/cct and phlp2a (1 MDa, Complex)

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EMD-23526

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Human TRiC/CCT complex with reovirus outer capsid protein sigma-3

Release date: March 3, 2021
Resolution: 6.2 Å
EM Method: Single-particle
Fitted PDBs: 7lup
Q-score: 0.217

Knowlton JJ, Gestaut D, Ma B, Taylor G, Seven AB, Leitner A, Wilson GJ, Shanker S, Yates NA, Prasad BVV, Aebersold R, Chiu W, Frydman J, Dermody TS

PNAS (2021) 118 [ DOI: doi:10.1073/pnas.2018127118 Pubmed: 33836586 ]

Sample:

Water (18 Da, Ligand)
T-complex protein 1 subunit beta (57 kDa, Protein from Homo sapiens)
T-complex protein 1 subunit eta (59 kDa, Protein from Homo sapiens)
Human tric/cct complex with reovirus outer capsid protein sigma-3 (41 MDa, Complex)
T-complex protein 1 subunit gamma (60 kDa, Protein from Homo sapiens)
T-complex protein 1 subunit epsilon (59 kDa, Protein from Homo sapiens)
T-complex protein 1 subunit alpha (60 kDa, Protein from Homo sapiens)
Zinc ion (65 Da, Ligand)
T-complex protein 1 subunit theta (59 kDa, Protein from Homo sapiens)
Reovirus outer capsid protein sigma-3 (Complex from Mammalian orthoreovirus 3 Dearing)
Human tric/cct complex (Complex from Homo sapiens)
Outer capsid protein sigma-3 (41 kDa, Protein from Reovirus type 3 (strain Dearing))
T-complex protein 1 subunit delta (57 kDa, Protein from Homo sapiens)
T-complex protein 1 subunit zeta (58 kDa, Protein from Homo sapiens)

[Show more]

Sort by: Download

Showing 1 - 4 of 4. Page 1 of 1

Display: Statistics

Download

Select database:

EMDB [4]

Format:

Select the script type:

Shell (Unix-based) Batch (Windows-based)

Preview first 10

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