Type I-FHNH Cascade-dsDNA intermediate complex
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8ydb
Q-score: 0.443
Zhang C, Chen F, Wang F, Xu H, Xue J, Li Z
Mol Cell (2024) 84 pp. 3141- [ Pubmed: 39047725 DOI: doi:10.1016/j.molcel.2024.06.033 ]
- Cas8f fusion with hnh (39 kDa, Protein from Selenomonas sp.)
- Type i-fhnh cascade-dsdna intermediate complex (Complex from Selenomonas sp.)
- Cas5f (28 kDa, Protein from Selenomonas sp.)
- Nts (3 kDa, Macromolecule from Selenomonas sp.)
- Cas6f (20 kDa, Protein from Selenomonas sp.)
- Ts (10 kDa, Macromolecule from Selenomonas sp.)
- Cas7f (38 kDa, Protein from Selenomonas sp.)
- 60-nt crrna (19 kDa, RNA from Selenomonas sp.)
Type I-FHNH Cascade-dsDNA R-loop complex
Resolution: 3.44 Å
EM Method: Single-particle
Fitted PDBs: 8yeo
Q-score: 0.432
Zhang C, Chen F, Wang F, Xu H, Xue J, Li Z
Mol Cell (2024) 84 pp. 3141- [ Pubmed: 39047725 DOI: doi:10.1016/j.molcel.2024.06.033 ]
- Cas8f fusion with hnh (39 kDa, Protein from Selenomonas sp.)
- Cas5f (28 kDa, Protein from Selenomonas sp.)
- Nts (3 kDa, Macromolecule from Selenomonas sp.)
- Cas6f (20 kDa, Protein from Selenomonas sp.)
- Type i-fhnh cascade-dsdna r-loop complex (Complex from Selenomonas sp.)
- Cas7f (38 kDa, Protein from Selenomonas sp.)
- 60-nt crrna (19 kDa, RNA from Selenomonas sp.)
- Ts (15 kDa, Macromolecule from Selenomonas sp.)
Structure of CbCas9 bound to 20-nucleotide complementary DNA substrate
Resolution: 2.46 Å
EM Method: Single-particle
Fitted PDBs: 8iyq
Q-score: 0.513
Zhang S, Sun A, Qian JM, Lin S, Xing W, Yang Y, Zhu HZ, Zhou XY, Guo YS, Liu Y, Meng Y, Jin SL, Song W, Li CP, Li Z, Jin S, Wang JH, Dong MQ, Gao C, Chen C, Bai Y, Liu JG
Nature (2024) 630 pp. 484-492 [ DOI: doi:10.1038/s41586-024-07486-x Pubmed: 38811729 ]
- Sgrna (40 kDa, RNA from Chryseobacterium)
- Structure of cbcas9 bound to 20-nucleotide complementary dna substrate (228 kDa, Complex from Chryseobacterium)
- Ts (8 kDa, DNA from Chryseobacterium)
- Deadcbcas9 (170 kDa, Protein from Chryseobacterium)
- Nts (8 kDa, DNA from Chryseobacterium)
Structure of CbCas9 bound to 6-nucleotide complementary DNA substrate
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 8wmh
Q-score: 0.279
Zhang S, Sun A, Qian JM, Lin S, Xing W, Yang Y, Zhu HZ, Zhou XY, Guo YS, Liu Y, Meng Y, Jin SL, Song W, Li CP, Li Z, Jin S, Wang JH, Dong MQ, Gao C, Chen C, Bai Y, Liu JG
Nature (2024) 630 pp. 484-492 [ DOI: doi:10.1038/s41586-024-07486-x Pubmed: 38811729 ]
- Ts (8 kDa, DNA from Chryseobacterium)
- Sgrna (40 kDa, RNA from Chryseobacterium)
- Deadcbcas9 (170 kDa, Protein from Chryseobacterium)
- Structure of cbcas9 bound to 6-nucleotide complementary dna substrate (228 kDa, Complex from Chryseobacterium)
- Nts (8 kDa, DNA from Chryseobacterium)
Structure of CbCas9-PcrIIC1 complex bound to 28-bp DNA substrate (20-nt complementary)
Resolution: 2.98 Å
EM Method: Single-particle
Fitted PDBs: 8wmm
Q-score: 0.342
Zhang S, Sun A, Qian JM, Lin S, Xing W, Yang Y, Zhu HZ, Zhou XY, Guo YS, Liu Y, Meng Y, Jin SL, Song W, Li CP, Li Z, Jin S, Wang JH, Dong MQ, Gao C, Chen C, Bai Y, Liu JG
Nature (2024) 630 pp. 484-492 [ DOI: doi:10.1038/s41586-024-07486-x Pubmed: 38811729 ]
- Pcriic1 (15 kDa, Protein from Chryseobacterium)
- Sgrna (40 kDa, RNA from Chryseobacterium)
- Ts (8 kDa, DNA from Chryseobacterium)
- Structure of cbcas9-pcriic1 complex bound to 28-bp dna substrate (20-nt complementary) (469 kDa, Complex from Chryseobacterium)
- Deadcbcas9 (170 kDa, Protein from Chryseobacterium)
- Nts (8 kDa, DNA from Chryseobacterium)
- Magnesium ion (24 Da, Ligand)
CryoEM structure of isNS1 in complex with Fab56.2 and HDL
Chew BLA, Ngoh ANQ, Phoo WW, Chan KWK, Ser Z, Tulsian NK, Lim SS, Weng MJG, Watanabe S, Choy MM, Low J, Ooi EE, Ruedl C, Sobota RM, Vasudevan SG, Luo D
eLife (2024) 12 [ DOI: doi:10.7554/eLife.90762 Pubmed: 38787378 ]
- Ternary complex of fab56.2 with dengue virus nonstructural protein 1 and high density lipoprotein (Complex)
- Fab 56.2 heavy chain (Macromolecule from Mus musculus)
- Core protein (Macromolecule from Dengue virus type 2)
- Isns1ts (Complex from Dengue virus type 2)
- Monoclonal antibody fragment 56.2 (Complex from Mus musculus)
- Fab 56.2 light chain (Macromolecule from Mus musculus)
CryoEM structure of isNS1 in complex with Fab56.2
Chew BLA, Ngoh ANQ, Phoo WW, Chan KWK, Ser Z, Tulsian NK, Lim SS, Weng MJG, Watanabe S, Choy MM, Low J, Ooi EE, Ruedl C, Sobota RM, Vasudevan SG, Luo D
eLife (2024) 12 [ DOI: doi:10.7554/eLife.90762 Pubmed: 38787378 ]
- Ternary complex of fab56.2 with dengue virus nonstructural protein 1 and high density lipoprotein (Complex)
- Fab56.2 heavy chain (Macromolecule from Mus musculus)
- Fab56.2 (Complex from Mus musculus)
- Fab56.2 light chain (Macromolecule from Mus musculus)
- Core protein (Macromolecule from dengue virus type 2)
- Isns1ts (Complex from Dengue virus type 2)
CryoEM structure of type IV-A Csf-crRNAsp14-dsDNA ternary complex
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 7xfz
Q-score: 0.547
Cui N, Zhang JT, Liu Y, Liu Y, Liu XY, Wang C, Huang H, Jia N
Mol Cell (2023) 83 pp. 2493-2508.e5 [ DOI: doi:10.1016/j.molcel.2023.05.036 Pubmed: 37343553 ]
- Crrna (13 kDa, RNA from Pseudomonas aeruginosa)
- Zinc ion (65 Da, Ligand)
- Nts (6 kDa, DNA from Pseudomonas aeruginosa)
- Type iv-a csf (Complex from Pseudomonas aeruginosa)
- Csf3 (24 kDa, Protein from Pseudomonas aeruginosa)
- Crrna (Complex)
- Dsdna (Complex)
- Csf2 (37 kDa, Protein from Pseudomonas aeruginosa)
- Csf5 (29 kDa, Protein from Pseudomonas aeruginosa)
- Csf1 (28 kDa, Protein from Pseudomonas aeruginosa)
- Ts (11 kDa, DNA from Pseudomonas aeruginosa)
- Type iv-a csf-crrnasp14-dsdna ternary complex (Complex from Pseudomonas aeruginosa)
CryoEM structure of type IV-A Csf-crRNA-dsDNA ternary complex
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 7xg0
Q-score: 0.512
Cui N, Zhang JT, Liu Y, Liu Y, Liu XY, Wang C, Huang H, Jia N
Mol Cell (2023) 83 pp. 2493-2508.e5 [ DOI: doi:10.1016/j.molcel.2023.05.036 Pubmed: 37343553 ]
- Zinc ion (65 Da, Ligand)
- Type iv-a csf (Complex from Pseudomonas aeruginosa)
- Csf3 (24 kDa, Protein from Pseudomonas aeruginosa)
- Crrna (Complex)
- Dsdna (Complex)
- Csf2 (37 kDa, Protein from Pseudomonas aeruginosa)
- Csf5 (29 kDa, Protein from Pseudomonas aeruginosa)
- Nts (16 kDa, DNA from Pseudomonas aeruginosa)
- Type iv-a csf-crrna-dsdna ternary complex (Complex from Pseudomonas aeruginosa)
- Ts (16 kDa, DNA from Pseudomonas aeruginosa)
- Crrna (19 kDa, RNA from Pseudomonas aeruginosa)
- Csf1 (28 kDa, Protein from Pseudomonas aeruginosa)
CryoEM structure of type IV-A NTS-nicked dsDNA bound Csf-crRNA ternary complex
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 7xg2
Q-score: 0.453
Cui N, Zhang JT, Liu Y, Liu Y, Liu XY, Wang C, Huang H, Jia N
Mol Cell (2023) 83 pp. 2493-2508.e5 [ DOI: doi:10.1016/j.molcel.2023.05.036 Pubmed: 37343553 ]
- Zinc ion (65 Da, Ligand)
- Csf3 (24 kDa, Protein from Pseudomonas aeruginosa)
- Crrna (Complex)
- Dsdna (Complex)
- Csf2 (37 kDa, Protein from Pseudomonas aeruginosa)
- Csf5 (29 kDa, Protein from Pseudomonas aeruginosa)
- Csf (Complex from Pseudomonas aeruginosa)
- Ts (16 kDa, DNA from Pseudomonas aeruginosa)
- Type iv-a nts-nicked dsdna bound csf-crrna ternary complex (Complex from Pseudomonas aeruginosa)
- Crrna (19 kDa, RNA from Pseudomonas aeruginosa)
- Csf1 (28 kDa, Protein from Pseudomonas aeruginosa)
- Nts (13 kDa, DNA from Pseudomonas aeruginosa)