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sample_name:"Transcription elongation factor Spt4" AND software_ft:"RELION"
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Structure of complete, activated transcription complex Pol II-DSIF-PAF-SPT6 uncovers allosteric elongation activation by RTF1 (Map 1)

Release date: July 22, 2020
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 6ted
Q-score: 0.338

Vos SM, Farnung L, Linden A, Urlaub H, Cramer P

Nat Struct Mol Biol (2020) 27 pp. 668-677 [ DOI: doi:10.1038/s41594-020-0437-1 Pubmed: 32541898 ]

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RNA polymerase II elongation complex bound with Elf1 and Spt4/5, stalled at SHL(-5) of the nucleosome

Release date: Feb. 20, 2019
Resolution: 7.9 Å
EM Method: Single-particle
Fitted PDBs: 6j4w
Q-score: 0.123

Ehara H, Kujirai T, Fujino Y, Shirouzu M, Kurumizaka H, Sekine SI

Science (2019) 363 pp. 744-747 [ Pubmed: 30733384 DOI: doi:10.1126/science.aav8912 ]

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RNA polymerase II elongation complex bound with Elf1 and Spt4/5, stalled at SHL(-1) of the nucleosome (+1A)

Release date: Feb. 20, 2019
Resolution: 4.3 Å
EM Method: Single-particle
Fitted PDBs: 6j4x
Q-score: 0.233

Ehara H, Kujirai T, Fujino Y, Shirouzu M, Kurumizaka H, Sekine SI

Science (2019) 363 pp. 744-747 [ Pubmed: 30733384 DOI: doi:10.1126/science.aav8912 ]

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RNA polymerase II elongation complex bound with Elf1 and Spt4/5, stalled at SHL(-1) of the nucleosome (+1B)

Release date: Feb. 20, 2019
Resolution: 4.3 Å
EM Method: Single-particle
Fitted PDBs: 6j4y
Q-score: 0.235

Ehara H, Kujirai T, Fujino Y, Shirouzu M, Kurumizaka H, Sekine SI

Science (2019) 363 pp. 744-747 [ Pubmed: 30733384 DOI: doi:10.1126/science.aav8912 ]

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RNA polymerase II elongation complex bound with Spt4/5 and foreign DNA, stalled at SHL(-1) of the nucleosome

Release date: Feb. 20, 2019
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 6j4z
Q-score: 0.244

Ehara H, Kujirai T, Fujino Y, Shirouzu M, Kurumizaka H, Sekine SI

Science (2019) 363 pp. 744-747 [ Pubmed: 30733384 DOI: doi:10.1126/science.aav8912 ]

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RNA polymerase II elongation complex bound with Spt4/5 and foreign DNA, stalled at SHL(-1) of the nucleosome (tilted conformation)

Release date: Feb. 20, 2019
Resolution: 4.7 Å
EM Method: Single-particle
Fitted PDBs: 6j50
Q-score: 0.195

Ehara H, Kujirai T, Fujino Y, Shirouzu M, Kurumizaka H, Sekine SI

Science (2019) 363 pp. 744-747 [ Pubmed: 30733384 DOI: doi:10.1126/science.aav8912 ]

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RNA polymerase II elongation complex bound with Spt4/5 and foreign DNA, stalled at SHL(-1) of the nucleosome, weak Elf1 (+1 position)

Release date: Feb. 20, 2019
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 6j51
Q-score: 0.23

Ehara H, Kujirai T, Fujino Y, Shirouzu M, Kurumizaka H, Sekine SI

Science (2019) 363 pp. 744-747 [ Pubmed: 30733384 DOI: doi:10.1126/science.aav8912 ]

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RNA polymerase II elongation complex bound with Elf1 and Spt4/5, stalled at SHL(-1) of the nucleosome

Release date: Feb. 20, 2019
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 6ir9
Q-score: 0.264

Ehara H, Kujirai T, Fujino Y, Shirouzu M, Kurumizaka H, Sekine SI

Science (2019) 363 pp. 744-747 [ Pubmed: 30733384 DOI: doi:10.1126/science.aav8912 ]

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Structure of paused transcription complex Pol II-DSIF-NELF

Release date: Sept. 5, 2018
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 6gml
Q-score: 0.34

Vos SM, Farnung L, Urlaub H, Cramer P

Nature (2018) 560 pp. 601-606 [ Pubmed: 30135580 DOI: doi:10.1038/s41586-018-0442-2 ]

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Structure of activated transcription complex Pol II-DSIF-PAF-SPT6 (Map A)

Release date: Aug. 22, 2018
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 6gmh

Vos SM, Farnung L, Boehning M, Wigge C, Linden A, Urlaub H, Cramer P

Nature (2018) 560 pp. 607-612 [ DOI: doi:10.1038/s41586-018-0440-4 Pubmed: 30135578 ]

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