Cryo-EM structure of the human SAGA complex
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 8h7g
Q-score: 0.273
Zhang Y, Yin C, Yin Y, Wei M, Jing W, Peng C, Chen Z, Huang J
Cell Discov (2022) 8 pp. 125-125 [ DOI: doi:10.1038/s41421-022-00489-w Pubmed: 36414614 ]
- Transformation/transcription domain-associated protein (438 kDa, Protein from Homo sapiens)
- Human saga transcriptional coactivator complex (1 MDa, Complex from Homo sapiens)
- Splicing factor 3b subunit 3 (135 kDa, Protein from Homo sapiens)
- Transcription initiation protein spt3 homolog (35 kDa, Protein from Homo sapiens)
- Transcription initiation factor tfiid subunit 9 (29 kDa, Protein from Homo sapiens)
- Transcription factor spt20 homolog (85 kDa, Protein from Homo sapiens)
- Unassigned sequence (1 kDa, Protein from Homo sapiens)
- Transcription initiation factor tfiid subunit 12 (17 kDa, Protein from Homo sapiens)
- Ataxin-7 (95 kDa, Protein from Homo sapiens)
- Staga complex 65 subunit gamma (50 kDa, Protein from Homo sapiens)
- Splicing factor 3b subunit 5 (10 kDa, Protein from Homo sapiens)
- Taf6-like rna polymerase ii p300/cbp-associated factor-associated factor 65 kda subunit 6l (67 kDa, Protein from Homo sapiens)
- Transcriptional adapter 1 (41 kDa, Protein from Homo sapiens)
- Transcription initiation factor tfiid subunit 10 (21 kDa, Protein from Homo sapiens)
- Taf5-like rna polymerase ii p300/cbp-associated factor-associated factor 65 kda subunit 5l (66 kDa, Protein from Homo sapiens)
Cryo-EM structure of the human SAGA coactivator complex (TRRAP, core)
Resolution: 2.93 Å
EM Method: Single-particle
Fitted PDBs: 7ktr
Q-score: 0.513
Herbst DA, Esbin MN, Louder RK, Dugast-Darzacq C, Dailey GM, Fang Q, Darzacq X, Tjian R, Nogales E
Nat Struct Mol Biol (2021) 28 pp. 989-996 [ Pubmed: 34811519 DOI: doi:10.1038/s41594-021-00682-7 ]
- Human saga (Complex from Homo sapiens)
- Human saga (1 MDa, Complex)
- Transcription initiation factor tfiid subunit 10 (21 kDa, Protein from Homo sapiens)
- Transformation/transcription domain-associated protein,transformation/transcription domain-associated protein,transformation/transcription domain-associated protein,transformation/transcription domain-associated protein (353 kDa, Protein from Homo sapiens)
- Inositol hexakisphosphate (660 Da, Ligand)
- Isoform 3 of transcription factor spt20 homolog (88 kDa, Protein from Homo sapiens)
- Transcription initiation factor tfiid subunit 12 (17 kDa, Protein from Homo sapiens)
- Transcription initiation protein spt3 homolog,transcription initiation protein spt3 homolog,transcription initiation protein spt3 homolog (33 kDa, Protein from Homo sapiens)
- Transcriptional adapter 1 (37 kDa, Protein from Homo sapiens)
- Ataxin-7 (95 kDa, Protein from Homo sapiens)
- Staga complex 65 subunit gamma,dhaa,staga complex 65 subunit gamma,staga complex 65 subunit gamma,dhaa,staga complex 65 subunit gamma,staga complex 65 subunit gamma,dhaa (78 kDa, Protein from unclassified Rhodococcus)
- Taf6-like rna polymerase ii p300/cbp-associated factor-associated factor 65 kda subunit 6l (67 kDa, Protein from Homo sapiens)
- Transcription initiation factor tfiid subunit 9b (27 kDa, Protein from Homo sapiens)
- Staga complex 65 subunit gamma (Complex from Homo sapiens)
- Taf5-like rna polymerase ii p300/cbp-associated factor-associated factor 65 kda subunit 5l (66 kDa, Protein from Homo sapiens)
Negative stain EM structure of the human SAGA coactivator complex (TRRAP, core, splicing module)
Resolution: 19.09 Å
EM Method: Single-particle
Fitted PDBs: 7kts
Q-score: 0.048
Herbst DA, Esbin MN, Louder RK, Dugast-Darzacq C, Dailey GM, Fang Q, Darzacq X, Tjian R, Nogales E
Nat Struct Mol Biol (2021) 28 pp. 989-996 [ Pubmed: 34811519 DOI: doi:10.1038/s41594-021-00682-7 ]
- Human saga (Complex from Homo sapiens)
- Human saga (1 MDa, Complex)
- Splicing factor 3b subunit 3 (135 kDa, Protein from Homo sapiens)
- Transcription initiation factor tfiid subunit 10 (21 kDa, Protein from Homo sapiens)
- Taf6-like rna polymerase ii p300/cbp-associated factor-associated factor 65 kda subunit 6l,taf6-like rna polymerase ii p300/cbp-associated factor-associated factor 65 kda subunit 6l,taf6-like rna polymerase ii p300/cbp-associated factor-associated factor 65 kda subunit 6l (62 kDa, Protein from Homo sapiens)
- Isoform 3 of transcription factor spt20 homolog (88 kDa, Protein from Homo sapiens)
- Transcription initiation factor tfiid subunit 12 (17 kDa, Protein from Homo sapiens)
- Transcriptional adapter 1 (37 kDa, Protein from Homo sapiens)
- Ataxin-7 (95 kDa, Protein from Homo sapiens)
- Splicing factor 3b subunit 5 (10 kDa, Protein from Homo sapiens)
- Transcription initiation protein spt3 homolog,transcription initiation protein spt3 homolog,transcription initiation protein spt3 homolog (35 kDa, Protein from Homo sapiens)
- Transformation/transcription domain-associated protein,transformation/transcription domain-associated protein,transformation/transcription domain-associated protein,transformation/transcription domain-associated protein,transformation/transcription domain-associated protein (419 kDa, Protein from Homo sapiens)
- Transcription initiation factor tfiid subunit 9b (27 kDa, Protein from Homo sapiens)
- Staga complex 65 subunit gamma, dhaa,staga complex 65 subunit gamma,staga complex 65 subunit gamma, dhaa,staga complex 65 subunit gamma,staga complex 65 subunit gamma, dhaa (83 kDa, Protein from unclassified Rhodococcus)
- Staga complex 65 subunit gamma (Complex from Homo sapiens)
- Taf5-like rna polymerase ii p300/cbp-associated factor-associated factor 65 kda subunit 5l (66 kDa, Protein from Homo sapiens)