Cryo-EM structure of the human SAGA coactivator complex (TRRAP, core)
Resolution: 2.93 Å
EM Method: Single-particle
Fitted PDBs: 7ktr
Q-score: 0.513
Herbst DA, Esbin MN, Louder RK, Dugast-Darzacq C, Dailey GM, Fang Q, Darzacq X, Tjian R, Nogales E
Nat Struct Mol Biol (2021) 28 pp. 989-996 [ Pubmed: 34811519 DOI: doi:10.1038/s41594-021-00682-7 ]
- Transcription initiation factor tfiid subunit 10 (21 kDa, Protein from Homo sapiens)
- Ataxin-7 (95 kDa, Protein from Homo sapiens)
- Taf5-like rna polymerase ii p300/cbp-associated factor-associated factor 65 kda subunit 5l (66 kDa, Protein from Homo sapiens)
- Isoform 3 of transcription factor spt20 homolog (88 kDa, Protein from Homo sapiens)
- Transcription initiation factor tfiid subunit 9b (27 kDa, Protein from Homo sapiens)
- Transcription initiation protein spt3 homolog,transcription initiation protein spt3 homolog,transcription initiation protein spt3 homolog (33 kDa, Protein from Homo sapiens)
- Transcriptional adapter 1 (37 kDa, Protein from Homo sapiens)
- Transformation/transcription domain-associated protein,transformation/transcription domain-associated protein,transformation/transcription domain-associated protein,transformation/transcription domain-associated protein (353 kDa, Protein from Homo sapiens)
- Inositol hexakisphosphate (660 Da, Ligand)
- Human saga (Complex from Homo sapiens)
- Taf6-like rna polymerase ii p300/cbp-associated factor-associated factor 65 kda subunit 6l (67 kDa, Protein from Homo sapiens)
- Staga complex 65 subunit gamma (Complex from Homo sapiens)
- Human saga (1 MDa, Complex)
- Transcription initiation factor tfiid subunit 12 (17 kDa, Protein from Homo sapiens)
- Staga complex 65 subunit gamma,dhaa,staga complex 65 subunit gamma,staga complex 65 subunit gamma,dhaa,staga complex 65 subunit gamma,staga complex 65 subunit gamma,dhaa (78 kDa, Protein from unclassified Rhodococcus)
Negative stain EM structure of the human SAGA coactivator complex (TRRAP, core, splicing module)
Resolution: 19.09 Å
EM Method: Single-particle
Fitted PDBs: 7kts
Q-score: 0.048
Herbst DA, Esbin MN, Louder RK, Dugast-Darzacq C, Dailey GM, Fang Q, Darzacq X, Tjian R, Nogales E
Nat Struct Mol Biol (2021) 28 pp. 989-996 [ Pubmed: 34811519 DOI: doi:10.1038/s41594-021-00682-7 ]
- Transcription initiation factor tfiid subunit 10 (21 kDa, Protein from Homo sapiens)
- Ataxin-7 (95 kDa, Protein from Homo sapiens)
- Splicing factor 3b subunit 5 (10 kDa, Protein from Homo sapiens)
- Taf5-like rna polymerase ii p300/cbp-associated factor-associated factor 65 kda subunit 5l (66 kDa, Protein from Homo sapiens)
- Isoform 3 of transcription factor spt20 homolog (88 kDa, Protein from Homo sapiens)
- Transcription initiation factor tfiid subunit 9b (27 kDa, Protein from Homo sapiens)
- Transcriptional adapter 1 (37 kDa, Protein from Homo sapiens)
- Transcription initiation protein spt3 homolog,transcription initiation protein spt3 homolog,transcription initiation protein spt3 homolog (35 kDa, Protein from Homo sapiens)
- Human saga (Complex from Homo sapiens)
- Taf6-like rna polymerase ii p300/cbp-associated factor-associated factor 65 kda subunit 6l,taf6-like rna polymerase ii p300/cbp-associated factor-associated factor 65 kda subunit 6l,taf6-like rna polymerase ii p300/cbp-associated factor-associated factor 65 kda subunit 6l (62 kDa, Protein from Homo sapiens)
- Transformation/transcription domain-associated protein,transformation/transcription domain-associated protein,transformation/transcription domain-associated protein,transformation/transcription domain-associated protein,transformation/transcription domain-associated protein (419 kDa, Protein from Homo sapiens)
- Staga complex 65 subunit gamma (Complex from Homo sapiens)
- Human saga (1 MDa, Complex)
- Transcription initiation factor tfiid subunit 12 (17 kDa, Protein from Homo sapiens)
- Staga complex 65 subunit gamma, dhaa,staga complex 65 subunit gamma,staga complex 65 subunit gamma, dhaa,staga complex 65 subunit gamma,staga complex 65 subunit gamma, dhaa (83 kDa, Protein from unclassified Rhodococcus)
- Splicing factor 3b subunit 3 (135 kDa, Protein from Homo sapiens)