Klebl DP, McMillan SN, Risi C, Forgacs E, Virok B, Atherton JL, Stofella M, Winkelmann DA, Sobott F, Galkin VE, Knight PJ, Muench SP, Scarff CA, White HD
To Be Published
CryoEM structure of the primed actomyosin-5a complex
Resolution: 4.4 Å
EM Method: Single-particle
Fitted PDBs: 8r9v
Q-score: 0.148
Klebl DP, McMillan SN, Risi C, Forgacs E, Virok B, Atherton JL, Stofella M, Winkelmann DA, Sobott F, Galkin VE, Knight PJ, Muench SP, Scarff CA, White HD
To Be Published
- Primed actomyosin-5a complex (Complex from Mus musculus)
- Magnesium ion (24 Da, Ligand)
- Unconventional myosin-5a (Complex from Mus musculus)
- F-actin (Complex from Oryctolagus cuniculus)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Unconventional myosin-va (92 kDa, Protein from Mus musculus)
- Actin, alpha skeletal muscle (41 kDa, Protein from Oryctolagus cuniculus)
- Phosphate ion (94 Da, Ligand)
CryoEM structure of the post-powerstroke actomyosin-5a complex
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 8rbf
Q-score: 0.216
Klebl DP, McMillan SN, Risi C, Forgacs E, Virok B, Atherton JL, Stofella M, Winkelmann DA, Sobott F, Galkin VE, Knight PJ, Muench SP, Scarff CA, White HD
To Be Published
- Post-powerstroke actomyosin-5a complex (Complex from Mus musculus)
- Unconventional myosin-5a (Complex from Oryctolagus cuniculus)
- Magnesium ion (24 Da, Ligand)
- Unconventional myosin-va (87 kDa, Protein from Mus musculus)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Actin, alpha skeletal muscle (41 kDa, Protein from Oryctolagus cuniculus)
- F-actin (Complex)
CryoEM structure of primed myosin-5a (ADP-Pi state)
Resolution: 4.9 Å
EM Method: Single-particle
Fitted PDBs: 8rbg
Q-score: 0.208
Klebl DP, McMillan SN, Risi C, Forgacs E, Virok B, Atherton JL, Stofella M, Winkelmann DA, Sobott F, Galkin VE, Knight PJ, Muench SP, Scarff CA, White HD
To Be Published
- Magnesium ion (24 Da, Ligand)
- Unconventional myosin-5a (Complex from Mus musculus)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Unconventional myosin-va (92 kDa, Protein from Mus musculus)
- Phosphate ion (94 Da, Ligand)
Cryo-EM structure of actomyosin-5a-S1 with the full-length lever (nucleotide free, class A)
Gravett MSC, Klebl DP, Harlen OG, Read DJ, Muench SP, Harris SA, Peckham M
Structure (2024) 32 pp. 2316-2324.e6 [ DOI: doi:10.1016/j.str.2024.09.025 Pubmed: 39454567 ]
- Actin, alpha skeletal muscle (Complex from Oryctolagus cuniculus)
- Calmodulin-1 (Complex from Mus musculus)
- Myosin-5a bound to f-actin (20 kDa, Complex)
- Unconventional myosin-va bound to calmodulin-1 (Complex from Mus musculus)
Cryo-EM structure of actomyosin-5a-S1 with the full-length lever (nucleotide free, class B)
Gravett MSC, Klebl DP, Harlen OG, Read DJ, Muench SP, Harris SA, Peckham M
Structure (2024) 32 pp. 2316-2324.e6 [ DOI: doi:10.1016/j.str.2024.09.025 Pubmed: 39454567 ]
Cryo-EM structure of actomyosin-5a-S1 with the full-length lever (nucleotide free, class C)
Gravett MSC, Klebl DP, Harlen OG, Read DJ, Muench SP, Harris SA, Peckham M
Structure (2024) 32 pp. 2316-2324.e6 [ DOI: doi:10.1016/j.str.2024.09.025 Pubmed: 39454567 ]
- Unconventional myosin-va bound to calmodulin-1 (Complex from Mus musculus)
- Calmodulin-1 (Complex from Mus musculus)
- Actin, alpha skeletal muscle (Complex from Oryctolagus cuniculus)
- Myosin-5a bound to f-actin (20 kDa, Complex)
Cryo-EM structure of actomyosin-5a-S1 with the full-length lever (nucleotide free, class D)
Resolution: 7.5 Å
EM Method: Single-particle
Fitted PDBs: 8of8
Q-score: 0.112
Gravett MSC, Klebl DP, Harlen OG, Read DJ, Harris SA, Muench SP, Peckham M
To Be Published
- Myosin-5a bound to f-actin (20 kDa, Complex)
- Unconventional myosin-va with calmodulin-1 bound (Complex from Mus musculus)
- Calmodulin-1 (Complex from Mus musculus)
- Calmodulin-1 (16 kDa, Protein from Mus musculus)
- Actin, alpha skeletal muscle (41 kDa, Protein from Oryctolagus cuniculus)
- Unconventional myosin-va (106 kDa, Protein from Mus musculus)
- Actin, alpha skeletal muscle (Complex from Oryctolagus cuniculus)
Cryo-EM structure of actomyosin-5a-S1 with the full-length lever (nucleotide free, class E)
Gravett MSC, Klebl DP, Harlen OG, Read DJ, Muench SP, Harris SA, Peckham M
Structure (2024) 32 pp. 2316-2324.e6 [ DOI: doi:10.1016/j.str.2024.09.025 Pubmed: 39454567 ]
Cryo-EM structure of actomyosin-5a-S1 with the full-length lever (nucleotide free, class G)
Gravett MSC, Klebl DP, Harlen OG, Read DJ, Muench SP, Harris SA, Peckham M
Structure (2024) 32 pp. 2316-2324.e6 [ DOI: doi:10.1016/j.str.2024.09.025 Pubmed: 39454567 ]