Cryo-EM structure of immature Zika virus in complex with human antibody DV62.5 Fab
Resolution: 8.0 Å
EM Method: Single-particle
Fitted PDBs: 6lnt
Q-score: 0.127
Tan TY, Fibriansah G, Kostyuchenko VA, Ng TS, Lim XX, Zhang S, Lim XN, Wang J, Shi J, Morais MC, Corti D, Lok SM
Nat Commun (2020) 11 pp. 895-895 [ DOI: doi:10.1038/s41467-020-14647-9 Pubmed: 32060358 ]
- Capsid protein (12 kDa, Protein from Zika virus (isolate ZIKV/Human/French Polynesia/10087PF/2013))
- Pre-membrane protein (18 kDa, Protein from Zika virus (isolate ZIKV/Human/French Polynesia/10087PF/2013))
- Fab dv62.5 light-chain variable region (11 kDa, Protein from Homo sapiens)
- Anti-prm antibody dv62.5 (Complex from Homo sapiens)
- Envelope protein (54 kDa, Protein from Zika virus (isolate ZIKV/Human/French Polynesia/10087PF/2013))
- Zika virus (Complex from Zika virus ZIKV/H. sapiens/FrenchPolynesia/10087PF/2013)
- Zika virus zikv/h. sapiens/frenchpolynesia/10087pf/2013 (Virus)
- Fab dv62.5 heavy-chain variable region (13 kDa, Protein from Homo sapiens)
Cryo-EM structure of immature Zika virus
Resolution: 9.0 Å
EM Method: Single-particle
Fitted PDBs: 6lnu
Q-score: 0.133
Tan TY, Fibriansah G, Kostyuchenko VA, Ng TS, Lim XX, Zhang S, Lim XN, Wang J, Shi J, Morais MC, Corti D, Lok SM
Nat Commun (2020) 11 pp. 895-895 [ DOI: doi:10.1038/s41467-020-14647-9 Pubmed: 32060358 ]
- Genome polyprotein (54 kDa, Protein from Zika virus (isolate ZIKV/Human/French Polynesia/10087PF/2013))
- Zika virus zikv/h. sapiens/frenchpolynesia/10087pf/2013 (Virus from Zika virus ZIKV/H. sapiens/FrenchPolynesia/10087PF/2013)
- Genome polyprotein (18 kDa, Protein from Zika virus (isolate ZIKV/Human/French Polynesia/10087PF/2013))
Sub-tomogram averaging of immature Zika virus in complex with Fab DV62.5
Tan TY, Fibriansah G, Kostyuchenko VA, Ng TS, Lim XX, Zhang S, Lim XN, Wang J, Shi J, Morais MC, Corti D, Lok SM
Nat Commun (2020) 11 pp. 895-895 [ DOI: doi:10.1038/s41467-020-14647-9 Pubmed: 32060358 ]
Cryo-EM structure of zika virus complexed with Fab of ZKA190 at pH 8.0 and 37 celsius degree
Resolution: 22.0 Å
EM Method: Single-particle
Fitted PDBs: 5y0a
Q-score: 0.044
Wang J, Bardelli M, Espinosa DA, Pedotti M, Ng TS, Bianchi S, Simonelli L, Lim EXY, Foglierini M, Zatta F, Jaconi S, Beltramello M, Cameroni E, Fibriansah G, Shi J, Barca T, Pagani I, Rubio A, Broccoli V, Vicenzi E, Graham V, Pullan S, Dowall S, Hewson R, Jurt S, Zerbe O, Stettler K, Lanzavecchia A, Sallusto F, Cavalli A, Harris E, Lok SM, Varani L, Corti D
Cell (2017) 171 pp. 229-241.e15 [ Pubmed: 28938115 DOI: doi:10.1016/j.cell.2017.09.002 ]
- Variable region of fab zka190 light chain (11 kDa, Protein from Homo sapiens)
- Zika virus (Complex)
- Zika virus complexed with fab of a human monoclonal antibody named zka190 (Complex from Zika virus)
- Protein e (44 kDa, Protein from Zika virus (strain Mr 766))
- Fab zka190 (Complex)
- Variable region of fab zka190 heavy chain (14 kDa, Protein from Homo sapiens)
Wang J, Bardelli M, Espinosa DA, Pedotti M, Ng TS, Bianchi S, Simonelli L, Lim EXY, Foglierini M, Zatta F, Jaconi S, Beltramello M, Cameroni E, Fibriansah G, Shi J, Barca T, Pagani I, Rubio A, Broccoli V, Vicenzi E, Graham V, Pullan S, Dowall S, Hewson R, Jurt S, Zerbe O, Stettler K, Lanzavecchia A, Sallusto F, Cavalli A, Harris E, Lok SM, Varani L, Corti D
Cell (2017) 171 pp. 229-241.e15 [ Pubmed: 28938115 DOI: doi:10.1016/j.cell.2017.09.002 ]
Cryo-EM structure of thermally stable Zika virus strain H/PF/2013
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 5iz7
Q-score: 0.387
Kostyuchenko VA, Lim EX, Zhang S, Fibriansah G, Ng TS, Ooi JS, Shi J, Lok SM
Nature (2016) 533 pp. 425-428 [ DOI: doi:10.1038/nature17994 Pubmed: 27093288 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Structural protein m (8 kDa, Protein from Zika virus)
- Structural protein e (54 kDa, Protein from Zika virus)
- Zika virus (10 MDa, Virus from Zika virus)