CryoEM structure of non-structural protein 1 tetramer from ZIKA virus
CryoEM structure of ZIKV rsNS1
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8wn8
Q-score: 0.33
Chew BLA, Ngoh AQ, Phoo WW, Weng MJG, Sheng HJ, Chan KWK, Tan EYJ, Gelbart T, Xu C, Tan GS, Vasudevan SG, Luo D
Npj Viruses (2024) 2 pp. 14- [ DOI: doi:10.1038/s44298-024-00024-6 ]
- Non-structural protein 1 (41 kDa, Protein from Zika virus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Zika virus (Virus from Zika virus)
Tetrahymena Ribozyme scaffolded Zika Virus xrRNA
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8tjq
Q-score: 0.395
Nucleic Acids Res (2023) 51 pp. e100-e100 [ Pubmed: 37791881 DOI: doi:10.1093/nar/gkad784 ]
- Rna (440-mer) (142 kDa, RNA from Zika virus)
- Tetrahymena ribozyme scaffolded zika virus xrrna (Complex from Tetrahymena)
- Magnesium ion (24 Da, Ligand)
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8cxg
Q-score: 0.485
Liu W, Zhang XK, Gong DY, Dai XH, Sharma A, Zhang TH, Rey F, Zhou ZH
To Be Published
- C8 scfv heavy chain (13 kDa, Protein from Homo sapiens)
- Zika virus (Virus from Zika virus)
- C8 scfv light chain (12 kDa, Protein from Homo sapiens)
- Ankyrin repeat family a protein 2,envelope e protein (69 kDa, Protein from Zika virus)
- Membrane m protein (379 kDa, Protein from Zika virus)
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8cxh
Q-score: 0.535
Liu W, Zhang XK, Gong DY, Dai XH, Sharma A, Zhang TH, Rey F, Zhou ZH
To Be Published
- C10 light chain (11 kDa, Protein from Homo sapiens)
- C10 heavy chain (14 kDa, Protein from Homo sapiens)
- Zika virus (Virus from Zika virus)
- Ankyrin repeat family a protein 2,envelope e protein (69 kDa, Protein from Zika virus)
- Membrane m protein (379 kDa, Protein from Zika virus)
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8cxi
Q-score: 0.464
Liu W, Zhang XK, Gong DY, Dai XH, Sharma A, Zhang TH, Rey F, Zhou ZH
To Be Published
- Zika virus (Virus from Zika virus)
- A11 light chain (11 kDa, Protein from Homo sapiens)
- A11 heavy chain (14 kDa, Protein from Homo sapiens)
- Ankyrin repeat family a protein 2,envelope e protein (69 kDa, Protein from Zika virus)
- Membrane m protein (379 kDa, Protein from Zika virus)
Resolution: 5.9 Å
EM Method: Single-particle
Fitted PDBs: 7yar
Q-score: 0.134
Adams C, Carbaugh DL, Shu B, Ng TS, Castillo IN, Bhowmik R, Segovia-Chumbez B, Puhl AC, Graham S, Diehl SA, Lazear HM, Lok SM, de Silva AM, Premkumar L
PLoS Pathog (2023) 19 pp. e1010814-e1010814 [ DOI: doi:10.1371/journal.ppat.1010814 Pubmed: 36626401 ]
- E protein (54 kDa, Protein from Zika virus ZIKV/H. sapiens/FrenchPolynesia/10087PF/2013)
- Zika virus zikv/h. (Complex from Homo sapiens)
- Heavy chain, light chain (Complex)
- Zika virus zikv/h. sapiens/frenchpolynesia/10087pf/2013 (Complex from Zika virus ZIKV/H. sapiens/FrenchPolynesia/10087PF/2013)
- Heavy chain (24 kDa, Protein from Homo sapiens)
- Light chain (22 kDa, Protein from Homo sapiens)
- M protein (8 kDa, Protein from Zika virus ZIKV/H. sapiens/FrenchPolynesia/10087PF/2013)
Zika Virus particle bound with IgM antibody DH1017 Fab fragment
Resolution: 5.26 Å
EM Method: Single-particle
Fitted PDBs: 7t17
Q-score: 0.264
Singh T, Hwang KK, Miller AS, Jones RL, Lopez CA, Dulson SJ, Giuberti C, Gladden MA, Miller I, Webster HS, Eudailey JA, Luo K, Von Holle T, Edwards RJ, Valencia S, Burgomaster KE, Zhang S, Mangold JF, Tu JJ, Dennis M, Alam SM, Premkumar L, Dietze R, Pierson TC, Ooi EE, Lazear HM, Kuhn RJ, Permar SR, Bonsignori M
Cell (2022) 185 pp. 4826-4840.e17 [ DOI: doi:10.1016/j.cell.2022.10.023 Pubmed: 36402135 ]
- Core protein (42 kDa, Protein from Zika virus)
- Zika virus (Virus from Zika virus)
- Dh1017.igm fabc constant domain (10 kDa, Protein from Homo sapiens)
- Dh1017.igm igl (11 kDa, Protein from Homo sapiens)
- Dh1017.igm igh (13 kDa, Protein from Homo sapiens)
- Dh1017.igm lambdac constant domain (11 kDa, Protein from Homo sapiens)
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 7kcr
Q-score: 0.436
Sevvana M, Rogers TF, Miller AS, Long F, Klose T, Beutler N, Lai YC, Parren M, Walker LM, Buda G, Burton DR, Rossmann MG, Kuhn RJ
Viruses (2020) 12 [ Pubmed: 33255202 DOI: doi:10.3390/v12121346 ]
- Zika virus zikv/h. sapiens/frenchpolynesia/10087pf/2013 (Virus from Zika virus ZIKV/H. sapiens/FrenchPolynesia/10087PF/2013)
- Zika virus in complex with monoclonal antibody adi30056 (15 MDa, Complex)
- Adi30056 fab light chain variable region (11 kDa, Protein from Homo sapiens)
- Adi30056 fab heavy chain variable region (13 kDa, Protein from Homo sapiens)
- Envelope protein e (54 kDa, Protein from Zika virus ZIKV/H. sapiens/FrenchPolynesia/10087PF/2013)
- Membrane protein m (8 kDa, Protein from Zika virus ZIKV/H. sapiens/FrenchPolynesia/10087PF/2013)
- Monoclonal antibody adi30056 (Complex from Homo sapiens)