Resolution: 5.9 Å
EM Method: Single-particle
Fitted PDBs: 7yar
Q-score: 0.134
Adams C, Carbaugh DL, Shu B, Ng TS, Castillo IN, Bhowmik R, Segovia-Chumbez B, Puhl AC, Graham S, Diehl SA, Lazear HM, Lok SM, de Silva AM, Premkumar L
PLoS Pathog (2023) 19 pp. e1010814-e1010814 [ DOI: doi:10.1371/journal.ppat.1010814 Pubmed: 36626401 ]
- E protein (54 kDa, Protein from Zika virus ZIKV/H. sapiens/FrenchPolynesia/10087PF/2013)
- Zika virus zikv/h. (Complex from Homo sapiens)
- Heavy chain, light chain (Complex)
- Zika virus zikv/h. sapiens/frenchpolynesia/10087pf/2013 (Complex from Zika virus ZIKV/H. sapiens/FrenchPolynesia/10087PF/2013)
- Heavy chain (24 kDa, Protein from Homo sapiens)
- Light chain (22 kDa, Protein from Homo sapiens)
- M protein (8 kDa, Protein from Zika virus ZIKV/H. sapiens/FrenchPolynesia/10087PF/2013)
Helical reconstruction of Zika virus complexed with Fab C10
Resolution: 9.4 Å
EM Method: Helical reconstruction
Fitted PDBs: 7c2t
Q-score: 0.093
Morrone SR, Chew VSY, Lim XN, Ng TS, Kostyuchenko VA, Zhang S, Wirawan M, Chew PL, Lee J, Tan JL, Wang J, Tan TY, Shi J, Screaton G, Morais MC, Lok SM
Nat Commun (2020) 11 pp. 3112-3112 [ Pubmed: 32561757 DOI: doi:10.1038/s41467-020-16925-y ]
- Envelope protein (54 kDa, Protein from Zika virus)
- C10 fab (Complex from Homo sapiens)
- Zika virus h/pf/2013 strain (Complex from Zika virus)
- Heavy chain from fab c10 (14 kDa, Protein from Homo sapiens)
- Light chain from fab c10 (11 kDa, Protein from Homo sapiens)
- M protein (8 kDa, Protein from Zika virus)
- Helical reconstruction of zika virus complexed with fab c10 (Complex)
Cryo-EM structure of zika virus complexed with Fab SIgN-3C at pH 6.5
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 7bu8
Q-score: 0.397
Zhang S, Loy T, Ng TS, Lim XN, Chew SV, Tan TY, Xu M, Kostyuchenko VA, Tukijan F, Shi J, Fink K, Lok SM
Cell Rep (2020) 31 pp. 107584-107584 [ DOI: doi:10.1016/j.celrep.2020.107584 Pubmed: 32348755 ]
- Genome polyprotein (54 kDa, Protein from Zika virus ZIKV/H. sapiens/FrenchPolynesia/10087PF/2013)
- Sign-3c fab (Complex)
- Sign-3c fab heavy chain (14 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Zika virus (Complex from Homo sapiens)
- Sign-3c fab light chain (11 kDa, Protein from Homo sapiens)
- Zika virus m protein (8 kDa, Protein from Zika virus ZIKV/H. sapiens/FrenchPolynesia/10087PF/2013)
- Complex of zika virus with sign-3c fab (Complex from Zika virus ZIKV/H. sapiens/FrenchPolynesia/10087PF/2013)
Cryo-EM structure of zika virus complexed with Fab SIgN-3C at pH 8.0
Resolution: 4.8 Å
EM Method: Single-particle
Fitted PDBs: 7bua
Q-score: 0.249
Zhang S, Loy T, Ng TS, Lim XN, Chew SV, Tan TY, Xu M, Kostyuchenko VA, Tukijan F, Shi J, Fink K, Lok SM
Cell Rep (2020) 31 pp. 107584-107584 [ DOI: doi:10.1016/j.celrep.2020.107584 Pubmed: 32348755 ]
- Genome polyprotein (54 kDa, Protein from Zika virus ZIKV/H. sapiens/FrenchPolynesia/10087PF/2013)
- Sign-3c fab (Complex)
- Sign-3c fab heavy chain (14 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Zika virus (Complex from Homo sapiens)
- Sign-3c fab light chain (11 kDa, Protein from Homo sapiens)
- Zika virus m protein (8 kDa, Protein from Zika virus ZIKV/H. sapiens/FrenchPolynesia/10087PF/2013)
- Complex of zika virus with sign-3c fab (Complex from Zika virus ZIKV/H. sapiens/FrenchPolynesia/10087PF/2013)
Cryo-EM structure of immature Zika virus in complex with human antibody DV62.5 Fab
Resolution: 8.0 Å
EM Method: Single-particle
Fitted PDBs: 6lnt
Q-score: 0.127
Tan TY, Fibriansah G, Kostyuchenko VA, Ng TS, Lim XX, Zhang S, Lim XN, Wang J, Shi J, Morais MC, Corti D, Lok SM
Nat Commun (2020) 11 pp. 895-895 [ DOI: doi:10.1038/s41467-020-14647-9 Pubmed: 32060358 ]
- Capsid protein (12 kDa, Protein from Zika virus (isolate ZIKV/Human/French Polynesia/10087PF/2013))
- Pre-membrane protein (18 kDa, Protein from Zika virus (isolate ZIKV/Human/French Polynesia/10087PF/2013))
- Fab dv62.5 light-chain variable region (11 kDa, Protein from Homo sapiens)
- Anti-prm antibody dv62.5 (Complex from Homo sapiens)
- Envelope protein (54 kDa, Protein from Zika virus (isolate ZIKV/Human/French Polynesia/10087PF/2013))
- Zika virus (Complex from Zika virus ZIKV/H. sapiens/FrenchPolynesia/10087PF/2013)
- Zika virus zikv/h. sapiens/frenchpolynesia/10087pf/2013 (Virus)
- Fab dv62.5 heavy-chain variable region (13 kDa, Protein from Homo sapiens)
Cryo-EM structure of immature Zika virus
Resolution: 9.0 Å
EM Method: Single-particle
Fitted PDBs: 6lnu
Q-score: 0.133
Tan TY, Fibriansah G, Kostyuchenko VA, Ng TS, Lim XX, Zhang S, Lim XN, Wang J, Shi J, Morais MC, Corti D, Lok SM
Nat Commun (2020) 11 pp. 895-895 [ DOI: doi:10.1038/s41467-020-14647-9 Pubmed: 32060358 ]
- Genome polyprotein (54 kDa, Protein from Zika virus (isolate ZIKV/Human/French Polynesia/10087PF/2013))
- Zika virus zikv/h. sapiens/frenchpolynesia/10087pf/2013 (Virus from Zika virus ZIKV/H. sapiens/FrenchPolynesia/10087PF/2013)
- Genome polyprotein (18 kDa, Protein from Zika virus (isolate ZIKV/Human/French Polynesia/10087PF/2013))
Cryo-EM structure of zika virus complexed with Fab of ZKA190 at pH 8.0 and 37 celsius degree
Resolution: 22.0 Å
EM Method: Single-particle
Fitted PDBs: 5y0a
Q-score: 0.044
Wang J, Bardelli M, Espinosa DA, Pedotti M, Ng TS, Bianchi S, Simonelli L, Lim EXY, Foglierini M, Zatta F, Jaconi S, Beltramello M, Cameroni E, Fibriansah G, Shi J, Barca T, Pagani I, Rubio A, Broccoli V, Vicenzi E, Graham V, Pullan S, Dowall S, Hewson R, Jurt S, Zerbe O, Stettler K, Lanzavecchia A, Sallusto F, Cavalli A, Harris E, Lok SM, Varani L, Corti D
Cell (2017) 171 pp. 229-241.e15 [ Pubmed: 28938115 DOI: doi:10.1016/j.cell.2017.09.002 ]
- Variable region of fab zka190 light chain (11 kDa, Protein from Homo sapiens)
- Zika virus (Complex)
- Zika virus complexed with fab of a human monoclonal antibody named zka190 (Complex from Zika virus)
- Protein e (44 kDa, Protein from Zika virus (strain Mr 766))
- Fab zka190 (Complex)
- Variable region of fab zka190 heavy chain (14 kDa, Protein from Homo sapiens)
Cryo-EM structure of zika virus complexed with Fab C10 at pH 6.5
Resolution: 4.4 Å
EM Method: Single-particle
Fitted PDBs: 5h30
Q-score: 0.284
Zhang S, Kostyuchenko VA, Ng T-S, Lim X-N, Ooi JSG, Lambert S, Tan TY, Widman DG, Shi J, Baric RS, Lok S-M
Nat Commun (2016) 7 pp. 13679-13679 [ DOI: doi:10.1038/ncomms13679 Pubmed: 27882950 ]
- Zika virus complexed with c10 fab at ph 6.5 (Complex)
- Zika virus (Complex from Zika virus)
- Fab c10 (Complex)
- Igg c10 light chain (11 kDa, Protein from Homo sapiens)
- Structural protein e (54 kDa, Protein from Zika virus)
- Igg c10 heavy chain (14 kDa, Protein from Homo sapiens)
- Strutural protein m (8 kDa, Protein from Zika virus)
Cryo-EM structure of zika virus complexed with Fab C10 at pH 5.0
Resolution: 12.0 Å
EM Method: Single-particle
Fitted PDBs: 5h32
Q-score: 0.073
Zhang S, Kostyuchenko VA, Ng T-S, Lim X-N, Ooi JSG, Lambert S, Tan TY, Widman DG, Shi J, Baric RS, Lok S-M
Nat Commun (2016) 7 pp. 13679-13679 [ DOI: doi:10.1038/ncomms13679 Pubmed: 27882950 ]
- Fab c10 (Complex)
- Structural protein e (44 kDa, Protein from Zika virus)
- Zika virus (Complex from Zika virus)
- C10 igg light chain variable region (11 kDa, Protein from Homo sapiens)
- C10 igg heavy chain variable region (14 kDa, Protein from Homo sapiens)
- Zika virus complexed with fab c10 at ph 5.0 (Complex)
Cryo-EM structure of zika virus complexed with Fab C10 at pH 8.0
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 5h37
Q-score: 0.39
Zhang S, Kostyuchenko VA, Ng T-S, Lim X-N, Ooi JSG, Lambert S, Tan TY, Widman DG, Shi J, Baric RS, Lok S-M
Nat Commun (2016) 7 pp. 13679-13679 [ DOI: doi:10.1038/ncomms13679 Pubmed: 27882950 ]
- Zika virus complexed with c10 fab at ph 8.0 (Complex)
- Structural protein e (54 kDa, Protein from Zika virus)
- Zika virus (Complex from Zika virus)
- C10 igg light chain variable region (11 kDa, Protein from Homo sapiens)
- C10 igg heavy chain variable region (14 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- C10 fab (Complex)
- Strutural protein m (8 kDa, Protein from Zika virus)