Zika Virus particle bound with IgM antibody DH1017 Fab fragment
Resolution: 5.26 Å
EM Method: Single-particle
Fitted PDBs: 7t17
Q-score: 0.264
Singh T, Hwang KK, Miller AS, Jones RL, Lopez CA, Dulson SJ, Giuberti C, Gladden MA, Miller I, Webster HS, Eudailey JA, Luo K, Von Holle T, Edwards RJ, Valencia S, Burgomaster KE, Zhang S, Mangold JF, Tu JJ, Dennis M, Alam SM, Premkumar L, Dietze R, Pierson TC, Ooi EE, Lazear HM, Kuhn RJ, Permar SR, Bonsignori M
Cell (2022) 185 pp. 4826-4840.e17 [ DOI: doi:10.1016/j.cell.2022.10.023 Pubmed: 36402135 ]
- Core protein (42 kDa, Protein from Zika virus)
- Zika virus (Virus from Zika virus)
- Dh1017.igm fabc constant domain (10 kDa, Protein from Homo sapiens)
- Dh1017.igm igl (11 kDa, Protein from Homo sapiens)
- Dh1017.igm igh (13 kDa, Protein from Homo sapiens)
- Dh1017.igm lambdac constant domain (11 kDa, Protein from Homo sapiens)
Helical reconstruction of Zika virus complexed with Fab C10
Resolution: 9.4 Å
EM Method: Helical reconstruction
Fitted PDBs: 7c2t
Q-score: 0.093
Morrone SR, Chew VSY, Lim XN, Ng TS, Kostyuchenko VA, Zhang S, Wirawan M, Chew PL, Lee J, Tan JL, Wang J, Tan TY, Shi J, Screaton G, Morais MC, Lok SM
Nat Commun (2020) 11 pp. 3112-3112 [ Pubmed: 32561757 DOI: doi:10.1038/s41467-020-16925-y ]
- Envelope protein (54 kDa, Protein from Zika virus)
- C10 fab (Complex from Homo sapiens)
- Zika virus h/pf/2013 strain (Complex from Zika virus)
- Heavy chain from fab c10 (14 kDa, Protein from Homo sapiens)
- Light chain from fab c10 (11 kDa, Protein from Homo sapiens)
- M protein (8 kDa, Protein from Zika virus)
- Helical reconstruction of zika virus complexed with fab c10 (Complex)
Cryo-EM structure of zika virus complexed with Fab SIgN-3C at pH 6.5
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 7bu8
Q-score: 0.397
Zhang S, Loy T, Ng TS, Lim XN, Chew SV, Tan TY, Xu M, Kostyuchenko VA, Tukijan F, Shi J, Fink K, Lok SM
Cell Rep (2020) 31 pp. 107584-107584 [ DOI: doi:10.1016/j.celrep.2020.107584 Pubmed: 32348755 ]
- Genome polyprotein (54 kDa, Protein from Zika virus ZIKV/H. sapiens/FrenchPolynesia/10087PF/2013)
- Sign-3c fab (Complex)
- Sign-3c fab heavy chain (14 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Zika virus (Complex from Homo sapiens)
- Sign-3c fab light chain (11 kDa, Protein from Homo sapiens)
- Zika virus m protein (8 kDa, Protein from Zika virus ZIKV/H. sapiens/FrenchPolynesia/10087PF/2013)
- Complex of zika virus with sign-3c fab (Complex from Zika virus ZIKV/H. sapiens/FrenchPolynesia/10087PF/2013)
Cryo-EM structure of zika virus complexed with Fab SIgN-3C at pH 8.0
Resolution: 4.8 Å
EM Method: Single-particle
Fitted PDBs: 7bua
Q-score: 0.249
Zhang S, Loy T, Ng TS, Lim XN, Chew SV, Tan TY, Xu M, Kostyuchenko VA, Tukijan F, Shi J, Fink K, Lok SM
Cell Rep (2020) 31 pp. 107584-107584 [ DOI: doi:10.1016/j.celrep.2020.107584 Pubmed: 32348755 ]
- Genome polyprotein (54 kDa, Protein from Zika virus ZIKV/H. sapiens/FrenchPolynesia/10087PF/2013)
- Sign-3c fab (Complex)
- Sign-3c fab heavy chain (14 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Zika virus (Complex from Homo sapiens)
- Sign-3c fab light chain (11 kDa, Protein from Homo sapiens)
- Zika virus m protein (8 kDa, Protein from Zika virus ZIKV/H. sapiens/FrenchPolynesia/10087PF/2013)
- Complex of zika virus with sign-3c fab (Complex from Zika virus ZIKV/H. sapiens/FrenchPolynesia/10087PF/2013)
Cryo-EM structure of immature Zika virus in complex with human antibody DV62.5 Fab
Resolution: 8.0 Å
EM Method: Single-particle
Fitted PDBs: 6lnt
Q-score: 0.127
Tan TY, Fibriansah G, Kostyuchenko VA, Ng TS, Lim XX, Zhang S, Lim XN, Wang J, Shi J, Morais MC, Corti D, Lok SM
Nat Commun (2020) 11 pp. 895-895 [ DOI: doi:10.1038/s41467-020-14647-9 Pubmed: 32060358 ]
- Capsid protein (12 kDa, Protein from Zika virus (isolate ZIKV/Human/French Polynesia/10087PF/2013))
- Pre-membrane protein (18 kDa, Protein from Zika virus (isolate ZIKV/Human/French Polynesia/10087PF/2013))
- Fab dv62.5 light-chain variable region (11 kDa, Protein from Homo sapiens)
- Anti-prm antibody dv62.5 (Complex from Homo sapiens)
- Envelope protein (54 kDa, Protein from Zika virus (isolate ZIKV/Human/French Polynesia/10087PF/2013))
- Zika virus (Complex from Zika virus ZIKV/H. sapiens/FrenchPolynesia/10087PF/2013)
- Zika virus zikv/h. sapiens/frenchpolynesia/10087pf/2013 (Virus)
- Fab dv62.5 heavy-chain variable region (13 kDa, Protein from Homo sapiens)
Cryo-EM structure of immature Zika virus
Resolution: 9.0 Å
EM Method: Single-particle
Fitted PDBs: 6lnu
Q-score: 0.133
Tan TY, Fibriansah G, Kostyuchenko VA, Ng TS, Lim XX, Zhang S, Lim XN, Wang J, Shi J, Morais MC, Corti D, Lok SM
Nat Commun (2020) 11 pp. 895-895 [ DOI: doi:10.1038/s41467-020-14647-9 Pubmed: 32060358 ]
- Genome polyprotein (54 kDa, Protein from Zika virus (isolate ZIKV/Human/French Polynesia/10087PF/2013))
- Zika virus zikv/h. sapiens/frenchpolynesia/10087pf/2013 (Virus from Zika virus ZIKV/H. sapiens/FrenchPolynesia/10087PF/2013)
- Genome polyprotein (18 kDa, Protein from Zika virus (isolate ZIKV/Human/French Polynesia/10087PF/2013))
Cryo-EM structure of zika virus complexed with Fab C10 at pH 6.5
Resolution: 4.4 Å
EM Method: Single-particle
Fitted PDBs: 5h30
Q-score: 0.284
Zhang S, Kostyuchenko VA, Ng T-S, Lim X-N, Ooi JSG, Lambert S, Tan TY, Widman DG, Shi J, Baric RS, Lok S-M
Nat Commun (2016) 7 pp. 13679-13679 [ DOI: doi:10.1038/ncomms13679 Pubmed: 27882950 ]
- Zika virus complexed with c10 fab at ph 6.5 (Complex)
- Zika virus (Complex from Zika virus)
- Fab c10 (Complex)
- Igg c10 light chain (11 kDa, Protein from Homo sapiens)
- Structural protein e (54 kDa, Protein from Zika virus)
- Igg c10 heavy chain (14 kDa, Protein from Homo sapiens)
- Strutural protein m (8 kDa, Protein from Zika virus)
Cryo-EM structure of zika virus complexed with Fab C10 at pH 5.0
Resolution: 12.0 Å
EM Method: Single-particle
Fitted PDBs: 5h32
Q-score: 0.073
Zhang S, Kostyuchenko VA, Ng T-S, Lim X-N, Ooi JSG, Lambert S, Tan TY, Widman DG, Shi J, Baric RS, Lok S-M
Nat Commun (2016) 7 pp. 13679-13679 [ DOI: doi:10.1038/ncomms13679 Pubmed: 27882950 ]
- Fab c10 (Complex)
- Structural protein e (44 kDa, Protein from Zika virus)
- Zika virus (Complex from Zika virus)
- C10 igg light chain variable region (11 kDa, Protein from Homo sapiens)
- C10 igg heavy chain variable region (14 kDa, Protein from Homo sapiens)
- Zika virus complexed with fab c10 at ph 5.0 (Complex)
Cryo-EM structure of zika virus complexed with Fab C10 at pH 8.0
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 5h37
Q-score: 0.39
Zhang S, Kostyuchenko VA, Ng T-S, Lim X-N, Ooi JSG, Lambert S, Tan TY, Widman DG, Shi J, Baric RS, Lok S-M
Nat Commun (2016) 7 pp. 13679-13679 [ DOI: doi:10.1038/ncomms13679 Pubmed: 27882950 ]
- Zika virus complexed with c10 fab at ph 8.0 (Complex)
- Structural protein e (54 kDa, Protein from Zika virus)
- Zika virus (Complex from Zika virus)
- C10 igg light chain variable region (11 kDa, Protein from Homo sapiens)
- C10 igg heavy chain variable region (14 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- C10 fab (Complex)
- Strutural protein m (8 kDa, Protein from Zika virus)
Cryo-EM structure of thermally stable Zika virus strain H/PF/2013
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 5iz7
Q-score: 0.387
Kostyuchenko VA, Lim EX, Zhang S, Fibriansah G, Ng TS, Ooi JS, Shi J, Lok SM
Nature (2016) 533 pp. 425-428 [ DOI: doi:10.1038/nature17994 Pubmed: 27093288 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Structural protein m (8 kDa, Protein from Zika virus)
- Structural protein e (54 kDa, Protein from Zika virus)
- Zika virus (10 MDa, Virus from Zika virus)