Cryo-EM structure of immature Zika virus in complex with human antibody DV62.5 Fab
Resolution: 8.0 Å
EM Method: Single-particle
Fitted PDBs: 6lnt
Q-score: 0.127
Tan TY, Fibriansah G, Kostyuchenko VA, Ng TS, Lim XX, Zhang S, Lim XN, Wang J, Shi J, Morais MC, Corti D, Lok SM
Nat Commun (2020) 11 pp. 895-895 [ DOI: doi:10.1038/s41467-020-14647-9 Pubmed: 32060358 ]
- Capsid protein (12 kDa, Protein from Zika virus (isolate ZIKV/Human/French Polynesia/10087PF/2013))
- Pre-membrane protein (18 kDa, Protein from Zika virus (isolate ZIKV/Human/French Polynesia/10087PF/2013))
- Fab dv62.5 light-chain variable region (11 kDa, Protein from Homo sapiens)
- Anti-prm antibody dv62.5 (Complex from Homo sapiens)
- Envelope protein (54 kDa, Protein from Zika virus (isolate ZIKV/Human/French Polynesia/10087PF/2013))
- Zika virus (Complex from Zika virus ZIKV/H. sapiens/FrenchPolynesia/10087PF/2013)
- Zika virus zikv/h. sapiens/frenchpolynesia/10087pf/2013 (Virus)
- Fab dv62.5 heavy-chain variable region (13 kDa, Protein from Homo sapiens)
Cryo-EM structure of immature Zika virus
Resolution: 9.0 Å
EM Method: Single-particle
Fitted PDBs: 6lnu
Q-score: 0.133
Tan TY, Fibriansah G, Kostyuchenko VA, Ng TS, Lim XX, Zhang S, Lim XN, Wang J, Shi J, Morais MC, Corti D, Lok SM
Nat Commun (2020) 11 pp. 895-895 [ DOI: doi:10.1038/s41467-020-14647-9 Pubmed: 32060358 ]
- Genome polyprotein (54 kDa, Protein from Zika virus (isolate ZIKV/Human/French Polynesia/10087PF/2013))
- Zika virus zikv/h. sapiens/frenchpolynesia/10087pf/2013 (Virus from Zika virus ZIKV/H. sapiens/FrenchPolynesia/10087PF/2013)
- Genome polyprotein (18 kDa, Protein from Zika virus (isolate ZIKV/Human/French Polynesia/10087PF/2013))
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 6mid
Q-score: 0.451
Long F, Doyle M, Fernandez E, Miller AS, Klose T, Sevvana M, Bryan A, Davidson E, Doranz BJ, Kuhn RJ, Diamond MS, Crowe Jr JE, Rossmann MG
PNAS (2019) 116 pp. 1591-1596 [ Pubmed: 30642974 DOI: doi:10.1073/pnas.1815432116 ]
- E protein (54 kDa, Protein from Zika virus (isolate ZIKV/Human/French Polynesia/10087PF/2013))
- Monoclonal antibody zikv-195 heavy chain (14 kDa, Protein from Homo sapiens)
- Zikv virion in complex with fab fragments of the potently neutralizing human monoclonal antibody zikv-195 (Complex)
- Monoclonal antibody zikv-195 light chain (11 kDa, Protein from Homo sapiens)
- Monoclonal antibody zikv-195 (Complex from Homo sapiens)
- M protein (8 kDa, Protein from Zika virus (isolate ZIKV/Human/French Polynesia/10087PF/2013))
- Zika virus (isolate zikv/human/french polynesia/10087pf/2013) (Virus from Zika virus (isolate ZIKV/Human/French Polynesia/10087PF/2013))
Structure of Zika virus at a resolution of 3.1 Angstrom
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 6co8
Q-score: 0.507
Sevvana M, Long F, Miller AS, Klose T, Buda G, Sun L, Kuhn RJ, Rossmann MG
Structure (2018) 26 pp. 1169- [ DOI: doi:10.1016/j.str.2018.05.006 Pubmed: 29958768 ]
- Zika virus zikv/h. sapiens/frenchpolynesia/10087pf/2013 (Virus from Zika virus ZIKV/H. sapiens/FrenchPolynesia/10087PF/2013)
- M protein (8 kDa, Protein from Zika virus ZIKV/H. sapiens/FrenchPolynesia/10087PF/2013)
- E protein (54 kDa, Protein from Zika virus ZIKV/H. sapiens/FrenchPolynesia/10087PF/2013)
Cryo-EM structure of zika virus complexed with Fab of ZKA190 at pH 8.0 and 37 celsius degree
Resolution: 22.0 Å
EM Method: Single-particle
Fitted PDBs: 5y0a
Q-score: 0.044
Wang J, Bardelli M, Espinosa DA, Pedotti M, Ng TS, Bianchi S, Simonelli L, Lim EXY, Foglierini M, Zatta F, Jaconi S, Beltramello M, Cameroni E, Fibriansah G, Shi J, Barca T, Pagani I, Rubio A, Broccoli V, Vicenzi E, Graham V, Pullan S, Dowall S, Hewson R, Jurt S, Zerbe O, Stettler K, Lanzavecchia A, Sallusto F, Cavalli A, Harris E, Lok SM, Varani L, Corti D
Cell (2017) 171 pp. 229-241.e15 [ Pubmed: 28938115 DOI: doi:10.1016/j.cell.2017.09.002 ]
- Variable region of fab zka190 light chain (11 kDa, Protein from Homo sapiens)
- Zika virus (Complex)
- Zika virus complexed with fab of a human monoclonal antibody named zka190 (Complex from Zika virus)
- Protein e (44 kDa, Protein from Zika virus (strain Mr 766))
- Fab zka190 (Complex)
- Variable region of fab zka190 heavy chain (14 kDa, Protein from Homo sapiens)
A Human Antibody Against Zika Virus Crosslinks the E Protein to Prevent Infection
Resolution: 6.2 Å
EM Method: Single-particle
Fitted PDBs: 5uhy
Q-score: 0.148
Hasan SS, Miller A, Sapparapu G, Fernandez E, Klose T, Long F, Fokine A, Porta JC, Jiang W, Diamond MS, Crowe JE, Kuhn RJ, Rossmann MG
Nat Commun (2017) 8 pp. 14722-14722 [ DOI: doi:10.1038/ncomms14722 Pubmed: 28300075 ]
- Zv67 fab chain 1 (23 kDa, Protein from Homo sapiens)
- Zika virus with zikv117 fab (Complex from Zika virus)
- Envelope protein (43 kDa, Protein from Zika virus)
- Zv67 fab chain 2 (23 kDa, Protein from Homo sapiens)
Cryo-EM Structure of Immature Zika Virus
Resolution: 9.1 Å
EM Method: Single-particle
Fitted PDBs: 5u4w
Q-score: 0.079
Prasad VM, Miller AS, Klose T, Sirohi D, Buda G, Jiang W, Kuhn RJ, Rossmann MG
Nat Struct Mol Biol (2017) 24 pp. 184-186 [ DOI: doi:10.1038/nsmb.3352 Pubmed: 28067914 ]
- E protein (44 kDa, Protein from Zika virus)
- M protein (5 kDa, Protein from Zika virus)
- Transmembrane domains (Complex from Zika virus)
- Zika virus (Virus from Zika virus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Pr domain (9 kDa, Protein from Zika virus)
- Protein e (6 kDa, Protein from Zika virus)
- Beta-d-mannopyranose (180 Da, Ligand)
Zika virus complexed with a neutralizing antibody Z23-Fab
Resolution: 9.4 Å
EM Method: Single-particle
Fitted PDBs: 5gzr
Q-score: 0.102
Wang Q, Yang H, Liu X, Dai L, Ma T, Qi J, Wong G, Peng R, Liu S, Li J, Li S, Song J, Liu J, He J, Yuan H, Xiong Y, Liao Y, Li J, Yang J, Tong Z, Griffin BD, Bi Y, Liang M, Xu X, Qin C, Cheng G, Zhang X, Wang P, Qiu X, Kobinger G, Shi Y, Yan J, Gao GF
Sci Transl Med (2016) 8 pp. 369ra179-369ra179 [ Pubmed: 27974667 DOI: doi:10.1126/scitranslmed.aai8336 ]
- Zika virus (Complex from Zika virus)
- Z23 fab heavy chain (23 kDa, Protein from Homo sapiens)
- Structural protein e (54 kDa, Protein from Zika virus)
- Neutralizing antibody z23 fab (Complex)
- Z23 fab light chain (23 kDa, Protein from Homo sapiens)
- Strutural protein m (8 kDa, Protein from Zika virus)
- Zika virus in complex with a neutralizing antibody z23 fab (Complex)