CryoEM structure of ZIKV rsNS1
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8wn8
Q-score: 0.33
Chew BLA, Ngoh AQ, Phoo WW, Weng MJG, Sheng HJ, Chan KWK, Tan EYJ, Gelbart T, Xu C, Tan GS, Vasudevan SG, Luo D
Npj Viruses (2024) 2 pp. 14- [ DOI: doi:10.1038/s44298-024-00024-6 ]
- Non-structural protein 1 (41 kDa, Protein from Zika virus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Zika virus (Virus from Zika virus)
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8cxg
Q-score: 0.485
Liu W, Zhang XK, Gong DY, Dai XH, Sharma A, Zhang TH, Rey F, Zhou ZH
To Be Published
- C8 scfv heavy chain (13 kDa, Protein from Homo sapiens)
- Zika virus (Virus from Zika virus)
- C8 scfv light chain (12 kDa, Protein from Homo sapiens)
- Ankyrin repeat family a protein 2,envelope e protein (69 kDa, Protein from Zika virus)
- Membrane m protein (379 kDa, Protein from Zika virus)
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8cxh
Q-score: 0.535
Liu W, Zhang XK, Gong DY, Dai XH, Sharma A, Zhang TH, Rey F, Zhou ZH
To Be Published
- C10 light chain (11 kDa, Protein from Homo sapiens)
- C10 heavy chain (14 kDa, Protein from Homo sapiens)
- Zika virus (Virus from Zika virus)
- Ankyrin repeat family a protein 2,envelope e protein (69 kDa, Protein from Zika virus)
- Membrane m protein (379 kDa, Protein from Zika virus)
Resolution: 5.9 Å
EM Method: Single-particle
Fitted PDBs: 7yar
Q-score: 0.134
Adams C, Carbaugh DL, Shu B, Ng TS, Castillo IN, Bhowmik R, Segovia-Chumbez B, Puhl AC, Graham S, Diehl SA, Lazear HM, Lok SM, de Silva AM, Premkumar L
PLoS Pathog (2023) 19 pp. e1010814-e1010814 [ DOI: doi:10.1371/journal.ppat.1010814 Pubmed: 36626401 ]
- E protein (54 kDa, Protein from Zika virus ZIKV/H. sapiens/FrenchPolynesia/10087PF/2013)
- Zika virus zikv/h. (Complex from Homo sapiens)
- Heavy chain, light chain (Complex)
- Zika virus zikv/h. sapiens/frenchpolynesia/10087pf/2013 (Complex from Zika virus ZIKV/H. sapiens/FrenchPolynesia/10087PF/2013)
- Heavy chain (24 kDa, Protein from Homo sapiens)
- Light chain (22 kDa, Protein from Homo sapiens)
- M protein (8 kDa, Protein from Zika virus ZIKV/H. sapiens/FrenchPolynesia/10087PF/2013)
Zika Virus particle bound with IgM antibody DH1017 Fab fragment
Resolution: 5.26 Å
EM Method: Single-particle
Fitted PDBs: 7t17
Q-score: 0.264
Singh T, Hwang KK, Miller AS, Jones RL, Lopez CA, Dulson SJ, Giuberti C, Gladden MA, Miller I, Webster HS, Eudailey JA, Luo K, Von Holle T, Edwards RJ, Valencia S, Burgomaster KE, Zhang S, Mangold JF, Tu JJ, Dennis M, Alam SM, Premkumar L, Dietze R, Pierson TC, Ooi EE, Lazear HM, Kuhn RJ, Permar SR, Bonsignori M
Cell (2022) 185 pp. 4826-4840.e17 [ DOI: doi:10.1016/j.cell.2022.10.023 Pubmed: 36402135 ]
- Core protein (42 kDa, Protein from Zika virus)
- Zika virus (Virus from Zika virus)
- Dh1017.igm fabc constant domain (10 kDa, Protein from Homo sapiens)
- Dh1017.igm igl (11 kDa, Protein from Homo sapiens)
- Dh1017.igm igh (13 kDa, Protein from Homo sapiens)
- Dh1017.igm lambdac constant domain (11 kDa, Protein from Homo sapiens)
Cryo-EM structure of zika virus complexed with Fab SIgN-3C at pH 6.5
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 7bu8
Q-score: 0.397
Zhang S, Loy T, Ng TS, Lim XN, Chew SV, Tan TY, Xu M, Kostyuchenko VA, Tukijan F, Shi J, Fink K, Lok SM
Cell Rep (2020) 31 pp. 107584-107584 [ DOI: doi:10.1016/j.celrep.2020.107584 Pubmed: 32348755 ]
- Genome polyprotein (54 kDa, Protein from Zika virus ZIKV/H. sapiens/FrenchPolynesia/10087PF/2013)
- Sign-3c fab (Complex)
- Sign-3c fab heavy chain (14 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Zika virus (Complex from Homo sapiens)
- Sign-3c fab light chain (11 kDa, Protein from Homo sapiens)
- Zika virus m protein (8 kDa, Protein from Zika virus ZIKV/H. sapiens/FrenchPolynesia/10087PF/2013)
- Complex of zika virus with sign-3c fab (Complex from Zika virus ZIKV/H. sapiens/FrenchPolynesia/10087PF/2013)
Cryo-EM structure of zika virus complexed with Fab SIgN-3C at pH 8.0
Resolution: 4.8 Å
EM Method: Single-particle
Fitted PDBs: 7bua
Q-score: 0.249
Zhang S, Loy T, Ng TS, Lim XN, Chew SV, Tan TY, Xu M, Kostyuchenko VA, Tukijan F, Shi J, Fink K, Lok SM
Cell Rep (2020) 31 pp. 107584-107584 [ DOI: doi:10.1016/j.celrep.2020.107584 Pubmed: 32348755 ]
- Genome polyprotein (54 kDa, Protein from Zika virus ZIKV/H. sapiens/FrenchPolynesia/10087PF/2013)
- Sign-3c fab (Complex)
- Sign-3c fab heavy chain (14 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Zika virus (Complex from Homo sapiens)
- Sign-3c fab light chain (11 kDa, Protein from Homo sapiens)
- Zika virus m protein (8 kDa, Protein from Zika virus ZIKV/H. sapiens/FrenchPolynesia/10087PF/2013)
- Complex of zika virus with sign-3c fab (Complex from Zika virus ZIKV/H. sapiens/FrenchPolynesia/10087PF/2013)
Cryo-EM structure of immature Zika virus in complex with human antibody DV62.5 Fab
Resolution: 8.0 Å
EM Method: Single-particle
Fitted PDBs: 6lnt
Q-score: 0.127
Tan TY, Fibriansah G, Kostyuchenko VA, Ng TS, Lim XX, Zhang S, Lim XN, Wang J, Shi J, Morais MC, Corti D, Lok SM
Nat Commun (2020) 11 pp. 895-895 [ DOI: doi:10.1038/s41467-020-14647-9 Pubmed: 32060358 ]
- Capsid protein (12 kDa, Protein from Zika virus (isolate ZIKV/Human/French Polynesia/10087PF/2013))
- Pre-membrane protein (18 kDa, Protein from Zika virus (isolate ZIKV/Human/French Polynesia/10087PF/2013))
- Fab dv62.5 light-chain variable region (11 kDa, Protein from Homo sapiens)
- Anti-prm antibody dv62.5 (Complex from Homo sapiens)
- Envelope protein (54 kDa, Protein from Zika virus (isolate ZIKV/Human/French Polynesia/10087PF/2013))
- Zika virus (Complex from Zika virus ZIKV/H. sapiens/FrenchPolynesia/10087PF/2013)
- Zika virus zikv/h. sapiens/frenchpolynesia/10087pf/2013 (Virus)
- Fab dv62.5 heavy-chain variable region (13 kDa, Protein from Homo sapiens)
Cryo-EM structure of immature Zika virus
Resolution: 9.0 Å
EM Method: Single-particle
Fitted PDBs: 6lnu
Q-score: 0.133
Tan TY, Fibriansah G, Kostyuchenko VA, Ng TS, Lim XX, Zhang S, Lim XN, Wang J, Shi J, Morais MC, Corti D, Lok SM
Nat Commun (2020) 11 pp. 895-895 [ DOI: doi:10.1038/s41467-020-14647-9 Pubmed: 32060358 ]
- Genome polyprotein (54 kDa, Protein from Zika virus (isolate ZIKV/Human/French Polynesia/10087PF/2013))
- Zika virus zikv/h. sapiens/frenchpolynesia/10087pf/2013 (Virus from Zika virus ZIKV/H. sapiens/FrenchPolynesia/10087PF/2013)
- Genome polyprotein (18 kDa, Protein from Zika virus (isolate ZIKV/Human/French Polynesia/10087PF/2013))
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 6mid
Q-score: 0.451
Long F, Doyle M, Fernandez E, Miller AS, Klose T, Sevvana M, Bryan A, Davidson E, Doranz BJ, Kuhn RJ, Diamond MS, Crowe Jr JE, Rossmann MG
PNAS (2019) 116 pp. 1591-1596 [ Pubmed: 30642974 DOI: doi:10.1073/pnas.1815432116 ]
- E protein (54 kDa, Protein from Zika virus (isolate ZIKV/Human/French Polynesia/10087PF/2013))
- Monoclonal antibody zikv-195 heavy chain (14 kDa, Protein from Homo sapiens)
- Zikv virion in complex with fab fragments of the potently neutralizing human monoclonal antibody zikv-195 (Complex)
- Monoclonal antibody zikv-195 light chain (11 kDa, Protein from Homo sapiens)
- Monoclonal antibody zikv-195 (Complex from Homo sapiens)
- M protein (8 kDa, Protein from Zika virus (isolate ZIKV/Human/French Polynesia/10087PF/2013))
- Zika virus (isolate zikv/human/french polynesia/10087pf/2013) (Virus from Zika virus (isolate ZIKV/Human/French Polynesia/10087PF/2013))