Cryo-EM structure of inactive FZD1
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8j9o
Q-score: 0.347
Zhang Z, Lin X, Wei L, Wu Y, Xu L, Wu L, Wei X, Zhao S, Zhu X, Xu F
Cell Discov (2024) 10 pp. 3-3 [ Pubmed: 38182578 DOI: doi:10.1038/s41421-023-00627-y ]
- Frizzled-1 with icl3-bril complex with anti-bril fab (Complex from Homo sapiens)
- Frizzled-1,soluble cytochrome b562 (75 kDa, Protein from Homo sapiens)
- Anti-bril fab light chain (24 kDa, Protein from Mus)
- Anti-bril fab heavy chain (28 kDa, Protein from Mus)
- Anti-fab nanobody (13 kDa, Protein from Vicugna pacos)
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8jh7
Q-score: 0.354
Zhang Z, Lin X, Wei L, Wu Y, Xu L, Wu L, Wei X, Zhao S, Zhu X, Xu F
Cell Discov (2024) 10 pp. 3-3 [ Pubmed: 38182578 DOI: doi:10.1038/s41421-023-00627-y ]
- Anti-bril fab light chain (23 kDa, Protein from Homo sapiens)
- Complex of human fzd6 in inactivate state with accessory proteins. (Complex from Homo sapiens)
- Frizzled-6,soluble cytochrome b562 (73 kDa, Protein from Homo sapiens)
- Anti-fab nanobody (14 kDa, Protein from synthetic construct)
- Anti-bril fab heavy chain (25 kDa, Protein from Homo sapiens)
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 8jhc
Q-score: 0.387
Zhang Z, Lin X, Wei L, Wu Y, Xu L, Wu L, Wei X, Zhao S, Zhu X, Xu F
Cell Discov (2024) 10 pp. 3-3 [ Pubmed: 38182578 DOI: doi:10.1038/s41421-023-00627-y ]
- Complex of fzd3 with anti-bril fab and anti-fab nanobody (Complex from Homo sapiens)
- Anti-fab nanobody (14 kDa, Protein from synthetic construct)
- Anti-bril fab light chain (23 kDa, Protein from Homo sapiens)
- Frizzled-3,soluble cytochrome b562 (74 kDa, Protein from Homo sapiens)
- Anti-bril fab heavy chain (25 kDa, Protein from Homo sapiens)
Resolution: 2.98 Å
EM Method: Single-particle
Fitted PDBs: 7yud
Q-score: 0.53
Duan Y, Leong NCP, Zhao J, Zhang Y, Nguyen DT, Ha HTT, Wang N, Xia R, Xu Z, Ma Z, Qian Y, Yin H, Zhu X, Zhang A, Guo C, Xia Y, Nguyen LN, He Y
Cell Res (2024) 34 pp. 177-180 [ Pubmed: 38123825 DOI: doi:10.1038/s41422-023-00913-0 ]
- (2~{s})-2-azanyl-4-(4-octylphenyl)-2-[[oxidanyl-bis(oxidanylidene)-$l^{6}-phosphanyl]oxymethyl]butan-1-ol (387 Da, Ligand)
- Anti-fab nanobody (13 kDa, Protein from Lama glama)
- Sphingosine-1-phosphate transporter spns2 (58 kDa, Protein from Homo sapiens)
- Nbfab-h-chain (26 kDa, Protein from synthetic construct)
- Spns2 nanobody complex (Complex from Lama glama)
- Tc-nb8 (14 kDa, Protein from Lama glama)
- Nbfab l-chain (23 kDa, Protein from synthetic construct)
Resolution: 3.29 Å
EM Method: Single-particle
Fitted PDBs: 7yuf
Q-score: 0.458
Duan Y, Leong NCP, Zhao J, Zhang Y, Nguyen DT, Ha HTT, Wang N, Xia R, Xu Z, Ma Z, Qian Y, Yin H, Zhu X, Zhang A, Guo C, Xia Y, Nguyen LN, He Y
Cell Res (2024) 34 pp. 177-180 [ Pubmed: 38123825 DOI: doi:10.1038/s41422-023-00913-0 ]
- Antifab nanobody (13 kDa, Protein from Lama glama)
- Sphingosine-1-phosphate transporter spns2 (58 kDa, Protein from Homo sapiens)
- Nbfab h-chain (26 kDa, Protein from synthetic construct)
- Spns2 nanobody complex (Complex from Lama glama)
- Tc-nb8 (14 kDa, Protein from Lama glama)
- Nbfab l-chain (23 kDa, Protein from synthetic construct)