ZIKV rsNS1 in complex with Fab AA12 and anti-fab nanobody
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8wnp
Q-score: 0.428
Chew BLA, Ngoh AQ, Phoo WW, Weng MJG, Sheng HJ, Chan KWK, Tan EYJ, Gelbart T, Xu C, Tan GS, Vasudevan SG, Luo D
Npj Viruses (2024) 2 pp. 14- [ DOI: doi:10.1038/s44298-024-00024-6 ]
- Non-structural protein 1 (40 kDa, Protein from Zika virus)
- Vh chains (23 kDa, Protein from Homo sapiens)
- Vl chains (23 kDa, Protein from Homo sapiens)
- Anti-fab nanobody (13 kDa, Protein from Lama glama)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Zikv rsns1 in complex with fab aa12 and anti-fab nanobody (Complex from Zika virus)
ZIKV rsNS1 in complex with Fab GB5 and anti-fab nanobody
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 8wnu
Q-score: 0.331
Chew BLA, Ngoh AQ, Phoo WW, Weng MJG, Sheng HJ, Chan KWK, Tan EYJ, Gelbart T, Xu C, Tan GS, Vasudevan SG, Luo D
Npj Viruses (2024) 2 pp. 14- [ DOI: doi:10.1038/s44298-024-00024-6 ]
- Non-structural protein 1 (40 kDa, Protein from Zika virus)
- Vl (23 kDa, Protein from Homo sapiens)
- Zikv rsns1 in complex with fab gb5 and anti-fab nanobody (Complex from Zika virus)
- Vh (23 kDa, Protein from Homo sapiens)
- Anti-fab nanobody (13 kDa, Protein from Lama glama)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
ZIKV rsNS1 in complex with Fab EB9 and anti-fab nanobody
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 8wo4
Q-score: 0.416
Chew BLA, Ngoh AQ, Phoo WW, Weng MJG, Sheng HJ, Chan KWK, Tan EYJ, Gelbart T, Xu C, Tan GS, Vasudevan SG, Luo D
Npj Viruses (2024) 2 pp. 14- [ DOI: doi:10.1038/s44298-024-00024-6 ]
- Zikv rsns1 in complex with fab aa12 and anti-fab nanobody (Complex from Homo sapiens)
- Non-structural protein 1 (41 kDa, Protein from Zika virus)
- Anti-fab nanobody (15 kDa, Protein from Lama glama)
- Vl (23 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Vh (24 kDa, Protein from Homo sapiens)
The 5-MTHF-bound BRIL-SLC19A1/Fab/Nb ternary complex
Resolution: 3.54 Å
EM Method: Single-particle
Fitted PDBs: 8hij
Q-score: 0.296
Dang Y, Zhou D, Du X, Zhao H, Lee CH, Yang J, Wang Y, Qin C, Guo Z, Zhang Z
Cell Discov (2022) 8 pp. 141-141 [ Pubmed: 36575193 DOI: doi:10.1038/s41421-022-00508-w ]
- Bril-slc19a1 chimera (75 kDa, Protein from Homo sapiens)
- Anti-fab nanobody (16 kDa, Protein from Lama glama)
- N-[4-({[(6s)-2-amino-4-hydroxy-5-methyl-5,6,7,8-tetrahydropteridin-6-yl]methyl}amino)benzoyl]-l-glutamic acid (459 Da, Ligand)
- Anti-bril fab light chain (25 kDa, Protein from Homo sapiens)
- Anti-bril fab heavy chain (27 kDa, Protein from Homo sapiens)
- The 5-mthf-bound bril-slc19a1/fab/nb ternary complex (Complex from Homo sapiens)
The TPP-bound BRIL-SLC19A1/Fab/Nb ternary complex
Resolution: 3.72 Å
EM Method: Single-particle
Fitted PDBs: 8hik
Q-score: 0.249
Dang Y, Zhou D, Du X, Zhao H, Lee CH, Yang J, Wang Y, Qin C, Guo Z, Zhang Z
Cell Discov (2022) 8 pp. 141-141 [ Pubmed: 36575193 DOI: doi:10.1038/s41421-022-00508-w ]
- The tpp-bound bril-slc19a1/fab/nb ternary complex (Complex from Homo sapiens)
- Bril-slc19a1 chimera (75 kDa, Protein from Homo sapiens)
- Anti-fab nanobody (16 kDa, Protein from Lama glama)
- Anti-bril fab light chain (25 kDa, Protein from Homo sapiens)
- Anti-bril fab heavy chain (27 kDa, Protein from Homo sapiens)
- Thiamine diphosphate (425 Da, Ligand)
Cryo-EM structure of ACKR3 in complex with CXCL12 and an intracellular Fab
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 7sk5
Q-score: 0.438
Yen YC, Schafer CT, Gustavsson M, Eberle SA, Dominik PK, Deneka D, Zhang P, Schall TJ, Kossiakoff AA, Tesmer JJG, Handel TM
Sci Adv (2022) 8 pp. eabn8063-eabn8063 [ Pubmed: 35857509 DOI: doi:10.1126/sciadv.abn8063 ]
- Atypical chemokine receptor 3 (45 kDa, Protein from Homo sapiens)
- Stromal cell-derived factor 1 (7 kDa, Protein from Homo sapiens)
- Cid24 fab light chain (23 kDa, Protein from Homo sapiens)
- Cid24 fab heavy chain (25 kDa, Protein from Homo sapiens)
- Anti-fab nanobody (13 kDa, Protein from Lama glama)
- Complex structure of ackr3-cxcl12-cid24-nb (Complex)
- Cholesterol (386 Da, Ligand)
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 7sk7
Q-score: 0.514
Yen YC, Schafer CT, Gustavsson M, Eberle SA, Dominik PK, Deneka D, Zhang P, Schall TJ, Kossiakoff AA, Tesmer JJG, Handel TM
Sci Adv (2022) 8 pp. eabn8063-eabn8063 [ Pubmed: 35857509 DOI: doi:10.1126/sciadv.abn8063 ]
- Atypical chemokine receptor 3 (45 kDa, Protein from Homo sapiens)
- Stromal cell-derived factor 1 (7 kDa, Protein from Homo sapiens)
- (1r)-4-[7-(3-carboxypropoxy)-6-methylquinolin-8-yl]-1-{[2-(4-hydroxypiperidin-1-yl)-1,3-thiazol-4-yl]methyl}-1,4-diazepan-1-ium (540 Da, Ligand)
- Cid25 fab heavy chain (25 kDa, Protein from Homo sapiens)
- Complex structure of nb-cid25-ackr3-cxcl12-ccx662 (Complex)
- Cid25 fab light chain (23 kDa, Protein from Homo sapiens)
- Anti-fab nanobody (13 kDa, Protein from Lama glama)
- Cholesterol (386 Da, Ligand)
SARS-CoV-2 Omicron Variant S Trimer complexed with two JMB2002 Fab
Resolution: 2.69 Å
EM Method: Single-particle
Fitted PDBs: 7wpe
Q-score: 0.338
Yin W, Xu Y, Xu P, Cao X, Wu C, Gu C, He X, Wang X, Huang S, Yuan Q, Wu K, Hu W, Huang Z, Liu J, Wang Z, Jia F, Xia K, Liu P, Wang X, Song B, Zheng J, Jiang H, Cheng X, Jiang Y, Deng SJ, Xu HE
Science (2022) 375 pp. 1048-1053 [ Pubmed: 35133176 DOI: doi:10.1126/science.abn8863 ]
- Spike glycoprotein (133 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Anti-fab nanobody (Complex)
- Sars-cov-2 omicron variant s (Complex from Mus musculus)
- Jmb2002 fab heavy chain (25 kDa, Protein from Mus musculus)
- Jmb2002 fab (Complex from Lama glama)
- Sars-cov-2 omicron variant s trimer complexed with jmb2002 fab (Complex from Severe acute respiratory syndrome coronavirus)
- Anti-fab nanobody (14 kDa, Protein from Lama glama)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Jmb2002 fab light chian (23 kDa, Protein from Mus musculus)
SARS-CoV-2 Omicron Variant S Trimer complexed with one JMB2002 Fab
Resolution: 3.18 Å
EM Method: Single-particle
Fitted PDBs: 7wpd
Q-score: 0.265
Yin W, Xu Y, Xu P, Cao X, Wu C, Gu C, He X, Wang X, Huang S, Yuan Q, Wu K, Hu W, Huang Z, Liu J, Wang Z, Jia F, Xia K, Liu P, Wang X, Song B, Zheng J, Jiang H, Cheng X, Jiang Y, Deng SJ, Xu HE
Science (2022) 375 pp. 1048-1053 [ Pubmed: 35133176 DOI: doi:10.1126/science.abn8863 ]
- Anti fab nanobody (Complex)
- Spike glycoprotein (133 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Jmb2002 fab heavy chain (25 kDa, Protein from Mus musculus)
- Sars-cov-2 omicron variant s trimer complexed with jmb2002 fab (Complex from Severe acute respiratory syndrome coronavirus 2)
- Jmb2002 fab (Complex from Lama glama)
- Sars-cov-2 omicron variant s trimer (Complex from Mus musculus)
- Anti-fab nanobody (14 kDa, Protein from Lama glama)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Jmb2002 fab light chian (23 kDa, Protein from Mus musculus)
SARS-CoV-2 Omicron Variant S Trimer complexed with three JMB2002 Fab
Resolution: 2.92 Å
EM Method: Single-particle
Fitted PDBs: 7wpf
Q-score: 0.226
Yin W, Xu Y, Xu P, Cao X, Wu C, Gu C, He X, Wang X, Huang S, Yuan Q, Wu K, Hu W, Huang Z, Liu J, Wang Z, Jia F, Xia K, Liu P, Wang X, Song B, Zheng J, Jiang H, Cheng X, Jiang Y, Deng SJ, Xu HE
Science (2022) 375 pp. 1048-1053 [ Pubmed: 35133176 DOI: doi:10.1126/science.abn8863 ]
- Anti fab nanobody (Complex)
- Spike glycoprotein (133 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2 omicron variant s (Complex from Mus musculus)
- Jmb2002 fab heavy chain (25 kDa, Protein from Mus musculus)
- Sars-cov-2 omicron variant s trimer complexed with jmb2002 fab (Complex from Severe acute respiratory syndrome coronavirus 2)
- Jmb2002 fab (Complex from Lama glama)
- Jmb2002 fab light chain (23 kDa, Protein from Mus musculus)
- Anti-fab nanobody (14 kDa, Protein from Lama glama)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)