ZIKV rsNS1 in complex with Fab AA12 and anti-fab nanobody
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8wnp
Q-score: 0.428
Chew BLA, Ngoh AQ, Phoo WW, Weng MJG, Sheng HJ, Chan KWK, Tan EYJ, Gelbart T, Xu C, Tan GS, Vasudevan SG, Luo D
Npj Viruses (2024) 2 pp. 14- [ DOI: doi:10.1038/s44298-024-00024-6 ]
- Non-structural protein 1 (40 kDa, Protein from Zika virus)
- Vh chains (23 kDa, Protein from Homo sapiens)
- Vl chains (23 kDa, Protein from Homo sapiens)
- Anti-fab nanobody (13 kDa, Protein from Lama glama)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Zikv rsns1 in complex with fab aa12 and anti-fab nanobody (Complex from Zika virus)
ZIKV rsNS1 in complex with Fab GB5 and anti-fab nanobody
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 8wnu
Q-score: 0.331
Chew BLA, Ngoh AQ, Phoo WW, Weng MJG, Sheng HJ, Chan KWK, Tan EYJ, Gelbart T, Xu C, Tan GS, Vasudevan SG, Luo D
Npj Viruses (2024) 2 pp. 14- [ DOI: doi:10.1038/s44298-024-00024-6 ]
- Non-structural protein 1 (40 kDa, Protein from Zika virus)
- Vl (23 kDa, Protein from Homo sapiens)
- Zikv rsns1 in complex with fab gb5 and anti-fab nanobody (Complex from Zika virus)
- Vh (23 kDa, Protein from Homo sapiens)
- Anti-fab nanobody (13 kDa, Protein from Lama glama)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
ZIKV rsNS1 in complex with Fab EB9 and anti-fab nanobody
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 8wo4
Q-score: 0.416
Chew BLA, Ngoh AQ, Phoo WW, Weng MJG, Sheng HJ, Chan KWK, Tan EYJ, Gelbart T, Xu C, Tan GS, Vasudevan SG, Luo D
Npj Viruses (2024) 2 pp. 14- [ DOI: doi:10.1038/s44298-024-00024-6 ]
- Zikv rsns1 in complex with fab aa12 and anti-fab nanobody (Complex from Homo sapiens)
- Non-structural protein 1 (41 kDa, Protein from Zika virus)
- Anti-fab nanobody (15 kDa, Protein from Lama glama)
- Vl (23 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Vh (24 kDa, Protein from Homo sapiens)
Resolution: 4.16 Å
EM Method: Single-particle
Fitted PDBs: 9bei
Q-score: 0.276
Goverde CA, Pacesa M, Goldbach N, Dornfeld LJ, Balbi PEM, Georgeon S, Rosset S, Kapoor S, Choudhury J, Dauparas J, Schellhaas C, Kozlov S, Baker D, Ovchinnikov S, Vecchio AJ, Correia BE
Nature (2024) 631 pp. 449-458 [ DOI: doi:10.1038/s41586-024-07601-y Pubmed: 38898281 ]
- Cop-2 fab light chain (23 kDa, Protein from Escherichia coli)
- Claudin-4 (22 kDa, Protein from Homo sapiens)
- Synthetic human claudin-4 complex with clostridium perfringens enterotoxin c-terminal domain, sfab cop-2, and nanobody against cop-2 (103 kDa, Complex from Homo sapiens)
- Cop-2 fab heavy chain (25 kDa, Protein from Escherichia coli)
- Heat-labile enterotoxin b chain (14 kDa, Protein from Clostridium perfringens)
- Anti-fab nanobody (13 kDa, Protein from Escherichia coli)
The BRIL-SLC19A1/Fab/Nb ternary complex
Resolution: 3.57 Å
EM Method: Single-particle
Fitted PDBs: 8hii
Q-score: 0.338
Dang Y, Zhou D, Du X, Zhao H, Lee CH, Yang J, Wang Y, Qin C, Guo Z, Zhang Z
Cell Discov (2022) 8 pp. 141-141 [ Pubmed: 36575193 DOI: doi:10.1038/s41421-022-00508-w ]
- Bril-slc19a1 chimera (75 kDa, Protein from Homo sapiens)
- Anti-fab nanobody (16 kDa, Protein from Lama glama)
- The bril-slc19a1/fab/nb ternary complex (Complex from Homo sapiens)
- Anti-bril fab heavy chain (27 kDa, Protein from Homo sapiens)
- Anti-bril fab light chain (25 kDa, Protein from Homo sapiens)
The 5-MTHF-bound BRIL-SLC19A1/Fab/Nb ternary complex
Resolution: 3.54 Å
EM Method: Single-particle
Fitted PDBs: 8hij
Q-score: 0.296
Dang Y, Zhou D, Du X, Zhao H, Lee CH, Yang J, Wang Y, Qin C, Guo Z, Zhang Z
Cell Discov (2022) 8 pp. 141-141 [ Pubmed: 36575193 DOI: doi:10.1038/s41421-022-00508-w ]
- Bril-slc19a1 chimera (75 kDa, Protein from Homo sapiens)
- Anti-fab nanobody (16 kDa, Protein from Lama glama)
- N-[4-({[(6s)-2-amino-4-hydroxy-5-methyl-5,6,7,8-tetrahydropteridin-6-yl]methyl}amino)benzoyl]-l-glutamic acid (459 Da, Ligand)
- Anti-bril fab light chain (25 kDa, Protein from Homo sapiens)
- Anti-bril fab heavy chain (27 kDa, Protein from Homo sapiens)
- The 5-mthf-bound bril-slc19a1/fab/nb ternary complex (Complex from Homo sapiens)
The TPP-bound BRIL-SLC19A1/Fab/Nb ternary complex
Resolution: 3.72 Å
EM Method: Single-particle
Fitted PDBs: 8hik
Q-score: 0.249
Dang Y, Zhou D, Du X, Zhao H, Lee CH, Yang J, Wang Y, Qin C, Guo Z, Zhang Z
Cell Discov (2022) 8 pp. 141-141 [ Pubmed: 36575193 DOI: doi:10.1038/s41421-022-00508-w ]
- The tpp-bound bril-slc19a1/fab/nb ternary complex (Complex from Homo sapiens)
- Bril-slc19a1 chimera (75 kDa, Protein from Homo sapiens)
- Anti-fab nanobody (16 kDa, Protein from Lama glama)
- Anti-bril fab light chain (25 kDa, Protein from Homo sapiens)
- Anti-bril fab heavy chain (27 kDa, Protein from Homo sapiens)
- Thiamine diphosphate (425 Da, Ligand)
Cryo-EM structure of ACKR3 in complex with CXCL12 and an intracellular Fab
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 7sk5
Q-score: 0.438
Yen YC, Schafer CT, Gustavsson M, Eberle SA, Dominik PK, Deneka D, Zhang P, Schall TJ, Kossiakoff AA, Tesmer JJG, Handel TM
Sci Adv (2022) 8 pp. eabn8063-eabn8063 [ Pubmed: 35857509 DOI: doi:10.1126/sciadv.abn8063 ]
- Atypical chemokine receptor 3 (45 kDa, Protein from Homo sapiens)
- Stromal cell-derived factor 1 (7 kDa, Protein from Homo sapiens)
- Cid24 fab light chain (23 kDa, Protein from Homo sapiens)
- Cid24 fab heavy chain (25 kDa, Protein from Homo sapiens)
- Anti-fab nanobody (13 kDa, Protein from Lama glama)
- Complex structure of ackr3-cxcl12-cid24-nb (Complex)
- Cholesterol (386 Da, Ligand)
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 7sk7
Q-score: 0.514
Yen YC, Schafer CT, Gustavsson M, Eberle SA, Dominik PK, Deneka D, Zhang P, Schall TJ, Kossiakoff AA, Tesmer JJG, Handel TM
Sci Adv (2022) 8 pp. eabn8063-eabn8063 [ Pubmed: 35857509 DOI: doi:10.1126/sciadv.abn8063 ]
- Atypical chemokine receptor 3 (45 kDa, Protein from Homo sapiens)
- Stromal cell-derived factor 1 (7 kDa, Protein from Homo sapiens)
- (1r)-4-[7-(3-carboxypropoxy)-6-methylquinolin-8-yl]-1-{[2-(4-hydroxypiperidin-1-yl)-1,3-thiazol-4-yl]methyl}-1,4-diazepan-1-ium (540 Da, Ligand)
- Cid25 fab heavy chain (25 kDa, Protein from Homo sapiens)
- Complex structure of nb-cid25-ackr3-cxcl12-ccx662 (Complex)
- Cid25 fab light chain (23 kDa, Protein from Homo sapiens)
- Anti-fab nanobody (13 kDa, Protein from Lama glama)
- Cholesterol (386 Da, Ligand)
Structure of human Frizzled5 by fiducial-assisted cryo-EM
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 6ww2
Q-score: 0.42
Tsutsumi N, Mukherjee S, Waghray D, Janda CY, Jude KM, Miao Y, Burg JS, Aduri NG, Kossiakoff AA, Gati C, Garcia KC
eLife (2020) 9 [ Pubmed: 32762848 DOI: doi:10.7554/eLife.58464 ]
- Frizzled-5,soluble cytochrome b562 (74 kDa, Protein from Homo sapiens)
- Anti-fab nanobody (Complex)
- Frizzled-5 (Complex)
- Anti-bril fab (Complex)
- Anti-fab nanobody (13 kDa, Protein from synthetic construct)
- Anti-bril fab heavy chain (24 kDa, Protein from Homo sapiens)
- Anti-bril fab light chain (23 kDa, Protein from Homo sapiens)
- Fzd5-bril/fab/nb complex (100 kDa, Complex from Homo sapiens)