Cryo-EM structure of simian rotavirus SA11 VP4 in complex with nAb 7H13
Resolution: 3.47 Å
EM Method: Single-particle
Fitted PDBs: 8ygs
Q-score: 0.444
Huang Y, Song F, Zeng Y, Sun H, Sheng R, Wang X, Liu L, Luo G, Jiang Y, Chen Y, Zhang M, Zhang S, Gu Y, Yu H, Li S, Li T, Zheng Q, Ge S, Zhang J, Xia N
Nat Commun (2025) 16 pp. 838-838 [ Pubmed: 39833145 DOI: doi:10.1038/s41467-025-56114-3 ]
- Rotavirus vp4 (Complex from Rotavirus A)
- Immune complex of rotavirus with 7h13 (Complex from Rotavirus A)
- Fab 7h13 (Complex from Mus musculus)
- Antibody 7h13 heavy chain (12 kDa, Protein from Mus musculus)
- Outer capsid protein vp4 (64 kDa, Protein from Rotavirus A)
- Antibody 7h13 light chain (11 kDa, Protein from Mus musculus)
- Outer capsid protein vp4 (64 kDa, Protein from Rotavirus A)
Cryo-EM structure of simian rotavirus SA11 VP4 in complex with nAb 7H13-I54G mutant (left side)
Resolution: 3.01 Å
EM Method: Single-particle
Fitted PDBs: 8ygt
Q-score: 0.559
Huang Y, Song F, Zeng Y, Sun H, Sheng R, Wang X, Liu L, Luo G, Jiang Y, Chen Y, Zhang M, Zhang S, Gu Y, Yu H, Li S, Li T, Zheng Q, Ge S, Zhang J, Xia N
Nat Commun (2025) 16 pp. 838-838 [ Pubmed: 39833145 DOI: doi:10.1038/s41467-025-56114-3 ]
- Rotavirus vp4 (Complex from Rotavirus A)
- Immune complex of rotavirus with 7h13 (Complex from Rotavirus A)
- Fab 7h13 (Complex from Mus musculus)
- Antibody 7h13-i54g mutant heavy chain (12 kDa, Protein from Mus musculus)
- Antibody 7h13-i54g mutant light chain (11 kDa, Protein from Mus musculus)
- Outer capsid protein vp4 (64 kDa, Protein from Rotavirus A)
Cryo-EM structure of simian rotavirus SA11 VP4 in complex with nAb 7H13-I54G mutant (right side)
Resolution: 3.13 Å
EM Method: Single-particle
Fitted PDBs: 8ygu
Q-score: 0.526
Huang Y, Song F, Zeng Y, Sun H, Sheng R, Wang X, Liu L, Luo G, Jiang Y, Chen Y, Zhang M, Zhang S, Gu Y, Yu H, Li S, Li T, Zheng Q, Ge S, Zhang J, Xia N
Nat Commun (2025) 16 pp. 838-838 [ Pubmed: 39833145 DOI: doi:10.1038/s41467-025-56114-3 ]
- Rotavirus vp4 (Complex from Rotavirus A)
- Outer capsid protein vp4 (87 kDa, Protein from Rotavirus A)
- Immune complex of rotavirus with 7h13-i54g mutant (Complex from Rotavirus A)
- Fab 7h13 (Complex from Rotavirus A)
- Outer capsid protein vp4 (64 kDa, Protein from Rotavirus A)
- Antibody 7h13-i54g mutant light chain (11 kDa, Protein from Mus musculus)
- Antibody 7h13-i54g mutant heavy chain (12 kDa, Protein from Mus musculus)
cryo-EM structure of SARS-CoV-2 spike protein in complex with double nAbs 8H12 and VacW-209
Sun H, Deng T, Zhang Y, Lin Y, Jiang Y, Jiang Y, Huang Y, Song S, Cui L, Li T, Xiong H, Lan M, Liu L, Li Y, Fang Q, Yu K, Jiang W, Zhou L, Que Y, Zhang T, Yuan Q, Cheng T, Zhang Z, Yu H, Zhang J, Luo W, Li S, Zheng Q, Gu Y, Xia N
Protein Cell (2024) 15 pp. 121-134 [ Pubmed: 37470320 DOI: doi:10.1093/procel/pwad040 ]
SARS-CoV-2 S ectodomain trimer in complex with neutralizing antibody 10-5B
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 7xd2
Q-score: 0.367
Liu Y, Wang Z, Zhuang X, Zhang S, Chen Z, Zou Y, Sheng J, Li T, Tai W, Yu J, Wang Y, Zhang Z, Chen Y, Tong L, Yu X, Wu L, Chen D, Zhang R, Jin N, Shen W, Zhao J, Tian M, Wang X, Cheng G
Nat Commun (2023) 14 pp. 2179-2179 [ Pubmed: 37069158 DOI: doi:10.1038/s41467-023-37926-7 ]
- Spike+antibody (Complex from Severe acute respiratory syndrome coronavirus 2)
- L chian of antibody 10-5b (11 kDa, Protein from Homo sapiens)
- Spike glycoprotein (143 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- H chain of antibody 10-5b (12 kDa, Protein from Homo sapiens)
SARS-CoV-2 BA.4 variants S ectodomain trimer in complex with neutralizing antibody 10-5B and 6-2C
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8h07
Q-score: 0.298
Liu Y, Wang Z, Zhuang X, Zhang S, Chen Z, Zou Y, Sheng J, Li T, Tai W, Yu J, Wang Y, Zhang Z, Chen Y, Tong L, Yu X, Wu L, Chen D, Zhang R, Jin N, Shen W, Zhao J, Tian M, Wang X, Cheng G
Nat Commun (2023) 14 pp. 2179-2179 [ Pubmed: 37069158 DOI: doi:10.1038/s41467-023-37926-7 ]
- Sars-cov-2 ba.4 variants spike (Complex)
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 10-5b h chain (12 kDa, Protein from Homo sapiens)
- 10-5b l chain (11 kDa, Protein from Homo sapiens)
- 6-2c h chain (13 kDa, Protein from Homo sapiens)
- 6-2c l chain (11 kDa, Protein from Homo sapiens)
- Antibody (Cellular component from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Sars-cov-2 ba.4 variants spike (Cellular component from Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2 BA.1 variants S ectodomain trimer in complex with neutralizing antibody 10-5B and 6-2C
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8h08
Q-score: 0.3
Liu Y, Wang Z, Zhuang X, Zhang S, Chen Z, Zou Y, Sheng J, Li T, Tai W, Yu J, Wang Y, Zhang Z, Chen Y, Tong L, Yu X, Wu L, Chen D, Zhang R, Jin N, Shen W, Zhao J, Tian M, Wang X, Cheng G
Nat Commun (2023) 14 pp. 2179-2179 [ Pubmed: 37069158 DOI: doi:10.1038/s41467-023-37926-7 ]
- Sars-cov-2 ba.1 variants spike (Complex)
- Sars-cov-2 ba.1 variants spike (Cellular component from Severe acute respiratory syndrome coronavirus 2)
- 10-5b h chain (12 kDa, Protein from Homo sapiens)
- 10-5b l chain (11 kDa, Protein from Homo sapiens)
- 6-2c h chain (13 kDa, Protein from Homo sapiens)
- 6-2c l chain (11 kDa, Protein from Homo sapiens)
- Antibody (Cellular component from Homo sapiens)
- Spike glycoprotein (144 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
SARS-CoV-2 Spike trimer in complex with RmAb 9H1 Fab in the class 1 conformation
Resolution: 3.53 Å
EM Method: Single-particle
Fitted PDBs: 8heb
Q-score: 0.379
Chu X, Ding X, Yang Y, Lu Y, Li T, Gao Y, Zheng L, Xiao H, Yang T, Cheng H, Huang H, Liu Y, Lou Y, Wu C, Chen Y, Yang H, Ji X, Guo H
Biochem Biophys Res Commun (2023) 660 pp. 43-49 [ DOI: doi:10.1016/j.bbrc.2023.04.002 Pubmed: 37062240 ]
- Rabbit antibody 9h1 light chain (11 kDa, Protein from Oryctolagus cuniculus)
- Spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Rabbit antibody 9h1 heavy chain (12 kDa, Protein from Oryctolagus cuniculus)
- Sars-cov-2 wt spike glycoprotein complex with rmab 9h1 fabs (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike glycoprotein (133 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 9h1 fab (Complex)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
SARS-CoV-2 Spike trimer in complex with RmAb 9H1 Fab in the class 2 conformation
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 8hec
Q-score: 0.358
Chu X, Ding X, Yang Y, Lu Y, Li T, Gao Y, Zheng L, Xiao H, Yang T, Cheng H, Huang H, Liu Y, Lou Y, Wu C, Chen Y, Yang H, Ji X, Guo H
Biochem Biophys Res Commun (2023) 660 pp. 43-49 [ DOI: doi:10.1016/j.bbrc.2023.04.002 Pubmed: 37062240 ]
- Rabbit antibody 9h1 light chain (11 kDa, Protein from Oryctolagus cuniculus)
- Spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Rabbit antibody 9h1 heavy chain (12 kDa, Protein from Oryctolagus cuniculus)
- Sars-cov-2 wt spike glycoprotein complex with rmab 9h1 fabs (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike glycoprotein (133 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 9h1 fab (Complex)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Local refinement of the SARS-CoV-2 Spike trimer in complex with RmAb 9H1 Fab
Resolution: 3.59 Å
EM Method: Single-particle
Fitted PDBs: 8hed
Q-score: 0.469
Chu X, Ding X, Yang Y, Lu Y, Li T, Gao Y, Zheng L, Xiao H, Yang T, Cheng H, Huang H, Liu Y, Lou Y, Wu C, Chen Y, Yang H, Ji X, Guo H
Biochem Biophys Res Commun (2023) 660 pp. 43-49 [ DOI: doi:10.1016/j.bbrc.2023.04.002 Pubmed: 37062240 ]
- Spike protein s1 (22 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Rabbit antibody 9h1 light chain (11 kDa, Protein from Oryctolagus cuniculus)
- Sars-cov-2 wt spike glycoprotein rbd complex with 9h1 fabs (Complex from Severe acute respiratory syndrome coronavirus 2)
- Rabbit antibody 9h1 heavy chain (12 kDa, Protein from Oryctolagus cuniculus)
- Sars-cov-2 spike glycoprotein rbd (Complex from Oryctolagus cuniculus)
- 9h1 fab (Complex)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)