Saunders KO, Edwards RJ, Tilahun K, Manne K, Lu X, Cain DW, Wiehe K, Williams WB, Mansouri K, Hernandez GE, Sutherland L, Scearce R, Parks R, Barr M, DeMarco T, Eater CM, Eaton A, Morton G, Mildenberg B, Wang Y, Rountree RW, Tomai MA, Fox CB, Moody MA, Alam SM, Santra S, Lewis MG, Denny TN, Shaw GM, Montefiori DC, Acharya P, Haynes BF
Sci Transl Med (2022) 14 pp. eabo5598-eabo5598 [ Pubmed: 36070369 DOI: doi:10.1126/scitranslmed.abo5598 ]
- Hiv env ch505tfchim.6r.sosip.664.v4.1 trimer (Complex from Human immunodeficiency virus 2)
- Dh1024 antibody fab (Complex from Macaca mulatta)
- Dh1024 antibody fab light chain (Protein from Macaca mulatta)
- Complex of hiv env ch505tfchim.6r.sosip.664.v4.1 with dh1024 antibody fab (23 kDa, Complex from Human immunodeficiency virus 2)
- Hiv env ch505tfchim.6r.sosip.664.v4.1 (Protein from Human immunodeficiency virus 2)
- Dh1024 antibody fab light chain (Complex from Macaca mulatta)
- Dh1024 antibody fab heavy chain (Complex from Macaca mulatta)
- Dh1024 antibody fab heavy chain (Protein from Macaca mulatta)
Saunders KO, Edwards RJ, Tilahun K, Manne K, Lu X, Cain DW, Wiehe K, Williams WB, Mansouri K, Hernandez GE, Sutherland L, Scearce R, Parks R, Barr M, DeMarco T, Eater CM, Eaton A, Morton G, Mildenberg B, Wang Y, Rountree RW, Tomai MA, Fox CB, Moody MA, Alam SM, Santra S, Lewis MG, Denny TN, Shaw GM, Montefiori DC, Acharya P, Haynes BF
Sci Transl Med (2022) 14 pp. eabo5598-eabo5598 [ Pubmed: 36070369 DOI: doi:10.1126/scitranslmed.abo5598 ]
- Dh1025.1 antibody fab light chain (Complex from Macaca mulatta)
- Dh1025.1 antibody fab (Complex from Macaca mulatta)
- Dh1025.1 antibody fab heavy chain (Complex from Macaca mulatta)
- Hiv env ch505tfchim.6r.sosip.664.v4.1 trimer (Complex from Human immunodeficiency virus 2)
- Hiv env ch505tfchim.6r.sosip.664.v4.1 (Protein from Human immunodeficiency virus 1)
- Complex of hiv env ch505tfchim.6r.sosip.664.v4.1 with dh1025.1 antibody fab (23 kDa, Complex from Human immunodeficiency virus 2)
- Dh1025.1 antibody fab heavy chain (Protein from Macaca mulatta)
- Dh1025.1 antibody fab light chain (Protein from Macaca mulatta)
Saunders KO, Edwards RJ, Tilahun K, Manne K, Lu X, Cain DW, Wiehe K, Williams WB, Mansouri K, Hernandez GE, Sutherland L, Scearce R, Parks R, Barr M, DeMarco T, Eater CM, Eaton A, Morton G, Mildenberg B, Wang Y, Rountree RW, Tomai MA, Fox CB, Moody MA, Alam SM, Santra S, Lewis MG, Denny TN, Shaw GM, Montefiori DC, Acharya P, Haynes BF
Sci Transl Med (2022) 14 pp. eabo5598-eabo5598 [ Pubmed: 36070369 DOI: doi:10.1126/scitranslmed.abo5598 ]
- Hiv env ch505tfchim.6r.sosip.664.v4.1 trimer (Complex from Human immunodeficiency virus 2)
- Complex of hiv env ch505tfchim.6r.sosip.664.v4.1 with dh1027 antibody fab (23 kDa, Complex from Human immunodeficiency virus 2)
- Hiv env ch505tfchim.6r.sosip.664.v4.1 (Protein from Human immunodeficiency virus 1)
- Dh1027 antibody fab light chain (Complex from Macaca mulatta)
- Dh1027 antibody fab heavy chain (Protein from Macaca mulatta)
- Dh1027 antibody fab heavy chain (Complex from Macaca mulatta)
- Dh1027 antibody fab (Complex from Macaca mulatta)
- Dh1027 antibody fab light chain (Protein from Macaca mulatta)
Saunders KO, Edwards RJ, Tilahun K, Manne K, Lu X, Cain DW, Wiehe K, Williams WB, Mansouri K, Hernandez GE, Sutherland L, Scearce R, Parks R, Barr M, DeMarco T, Eater CM, Eaton A, Morton G, Mildenberg B, Wang Y, Rountree RW, Tomai MA, Fox CB, Moody MA, Alam SM, Santra S, Lewis MG, Denny TN, Shaw GM, Montefiori DC, Acharya P, Haynes BF
Sci Transl Med (2022) 14 pp. eabo5598-eabo5598 [ Pubmed: 36070369 DOI: doi:10.1126/scitranslmed.abo5598 ]
- Dh1028 antibody fab heavy chain (Protein from Macaca mulatta)
- Hiv env ch505tfchim.6r.sosip.664.v4.1 trimer (Complex from Human immunodeficiency virus 2)
- Complex of hiv env ch505tfchim.6r.sosip.664.v4.1 with dh1028 antibody fab (23 kDa, Complex from Human immunodeficiency virus 2)
- Dh1028 antibody fab light chain (Protein from Macaca mulatta)
- Dh1028 antibody fab light chain (Complex from Macaca mulatta)
- Dh1028 antibody fab heavy chain (Complex from Macaca mulatta)
- Hiv env ch505tfchim.6r.sosip.664.v4.1 (Protein from Human immunodeficiency virus 1)
- Dh1028 antibody fab (Complex from Macaca mulatta)
Saunders KO, Edwards RJ, Tilahun K, Manne K, Lu X, Cain DW, Wiehe K, Williams WB, Mansouri K, Hernandez GE, Sutherland L, Scearce R, Parks R, Barr M, DeMarco T, Eater CM, Eaton A, Morton G, Mildenberg B, Wang Y, Rountree RW, Tomai MA, Fox CB, Moody MA, Alam SM, Santra S, Lewis MG, Denny TN, Shaw GM, Montefiori DC, Acharya P, Haynes BF
Sci Transl Med (2022) 14 pp. eabo5598-eabo5598 [ Pubmed: 36070369 DOI: doi:10.1126/scitranslmed.abo5598 ]
- Dh950 antibody fab heavy chain (Complex from Homo sapiens)
- Hiv env ch505tfchim.6r.sosip.664.v4.1 trimer (Complex from Human immunodeficiency virus 2)
- Complex of hiv env ch505tfchim.6r.sosip.664.v4.1 with dh950 antibody fab (23 kDa, Complex from Human immunodeficiency virus 2)
- Dh950 antibody fab heavy chain (Protein from Homo sapiens)
- Dh950 antibody fab (Complex from Homo sapiens)
- Hiv env ch505tfchim.6r.sosip.664.v4.1 (Protein from Human immunodeficiency virus 1)
- Dh950 antibody fab light chain (Complex from Homo sapiens)
- Dh950 antibody fab light chain (Protein from Homo sapiens)
Enterovirus D68 in complex with human monoclonal antibody EV68-159
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 6wds
Q-score: 0.631
Vogt MR, Fu J, Kose N, Williamson LE, Bombardi R, Setliff I, Georgiev IS, Klose T, Rossmann MG, Bochkov YA, Gern JE, Kuhn RJ, Crowe Jr JE
Sci Immunol (2020) 5 [ Pubmed: 32620559 DOI: doi:10.1126/sciimmunol.aba4902 ]
- Viral protein 4 (7 kDa, Protein from Enterovirus D68)
- Viral protein 3 (27 kDa, Protein from Enterovirus D68)
- Viral protein 1 (32 kDa, Protein from Enterovirus D68)
- Viral protein 2 (27 kDa, Protein from Enterovirus D68)
- Ev68-159 heavy chain (13 kDa, Protein from Homo sapiens)
- Enterovirus d68 in complex with human monoclonal antibody ev68-159 (Complex)
- Enterovirus d68 (Virus from Enterovirus D68)
- Human antibody ev68-159 (Complex from Homo sapiens)
- Ev68-159 light chain (11 kDa, Protein from Homo sapiens)
Enterovirus D68 in complex with human monoclonal antibody EV68-228
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 6wdt
Q-score: 0.589
Vogt MR, Fu J, Kose N, Williamson LE, Bombardi R, Setliff I, Georgiev IS, Klose T, Rossmann MG, Bochkov YA, Gern JE, Kuhn RJ, Crowe Jr JE
Sci Immunol (2020) 5 [ Pubmed: 32620559 DOI: doi:10.1126/sciimmunol.aba4902 ]
- Viral protein 4 (7 kDa, Protein from Enterovirus D68)
- Ev68-228 light chain (11 kDa, Protein from Homo sapiens)
- Enterovirus d68 in complex with human monoclonal antibody ev68-228 (Complex)
- Viral protein 3 (27 kDa, Protein from Enterovirus D68)
- Viral protein 1 (32 kDa, Protein from Enterovirus D68)
- Viral protein 2 (27 kDa, Protein from Enterovirus D68)
- Enterovirus d68 (Virus from Enterovirus D68)
- Human monoclonal antibody ev68-228 (Complex from Homo sapiens)
- Ev68-228 heavy chain (14 kDa, Protein from Homo sapiens)
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 6mid
Q-score: 0.451
Long F, Doyle M, Fernandez E, Miller AS, Klose T, Sevvana M, Bryan A, Davidson E, Doranz BJ, Kuhn RJ, Diamond MS, Crowe Jr JE, Rossmann MG
PNAS (2019) 116 pp. 1591-1596 [ DOI: doi:10.1073/pnas.1815432116 Pubmed: 30642974 ]
- Zika virus (isolate zikv/human/french polynesia/10087pf/2013) (Virus from Zika virus (isolate ZIKV/Human/French Polynesia/10087PF/2013))
- Zikv virion in complex with fab fragments of the potently neutralizing human monoclonal antibody zikv-195 (Complex)
- M protein (8 kDa, Protein from Zika virus (isolate ZIKV/Human/French Polynesia/10087PF/2013))
- Monoclonal antibody zikv-195 light chain (11 kDa, Protein from Homo sapiens)
- E protein (54 kDa, Protein from Zika virus (isolate ZIKV/Human/French Polynesia/10087PF/2013))
- Monoclonal antibody zikv-195 (Complex from Homo sapiens)
- Monoclonal antibody zikv-195 heavy chain (14 kDa, Protein from Homo sapiens)
Structure of parvovirus B19 decorated with Fab molecules from a human antibody
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 6nn3
Q-score: 0.521
Rossmann MG, Sun Y, Klose T, Liu Y, Meng G
To Be Published
- Antibody 860-55d light chain (10 kDa, Protein from Homo sapiens)
- Human parvovirus b19 (Virus from Human parvovirus B19)
- Antibody 860-55d fab (Complex from Homo sapiens)
- Antibody 860-55d heavy chain (11 kDa, Protein from Homo sapiens)
- Vp2 (60 kDa, Protein from Human parvovirus B19)
- Complex of b19 vlp with fab molecules of antibody 860-55d (5 MDa, Complex)
Resolution: 2.53 Å
EM Method: Single-particle
Fitted PDBs: 5w3e
Q-score: 0.644
Dong Y, Liu Y, Jiang W, Smith TJ, Xu Z, Rossmann MG
PNAS (2017) 114 pp. 8017-8022 [ Pubmed: 28696310 DOI: doi:10.1073/pnas.1707369114 ]
- C5 antibody variable heavy domain (11 kDa, Protein from Mus musculus)
- Viral protein 3 (26 kDa, Protein from Human rhinovirus 14)
- Viral protein 4 (7 kDa, Protein from Human rhinovirus 14)
- Water (18 Da, Ligand)
- C5 antibody variable light domain (10 kDa, Protein from Mus musculus)
- Human rhinovirus b14 (Virus from Human rhinovirus B14)
- Viral protein 2 (28 kDa, Protein from Human rhinovirus 14)
- Viral protein 1 (32 kDa, Protein from Human rhinovirus 14)