Saunders KO, Edwards RJ, Tilahun K, Manne K, Lu X, Cain DW, Wiehe K, Williams WB, Mansouri K, Hernandez GE, Sutherland L, Scearce R, Parks R, Barr M, DeMarco T, Eater CM, Eaton A, Morton G, Mildenberg B, Wang Y, Rountree RW, Tomai MA, Fox CB, Moody MA, Alam SM, Santra S, Lewis MG, Denny TN, Shaw GM, Montefiori DC, Acharya P, Haynes BF
Sci Transl Med (2022) 14 pp. eabo5598-eabo5598 [ Pubmed: 36070369 DOI: doi:10.1126/scitranslmed.abo5598 ]
- Dh1025.1 antibody fab light chain (Complex from Macaca mulatta)
- Dh1025.1 antibody fab (Complex from Macaca mulatta)
- Dh1025.1 antibody fab heavy chain (Complex from Macaca mulatta)
- Hiv env ch505tfchim.6r.sosip.664.v4.1 trimer (Complex from Human immunodeficiency virus 2)
- Hiv env ch505tfchim.6r.sosip.664.v4.1 (Protein from Human immunodeficiency virus 1)
- Complex of hiv env ch505tfchim.6r.sosip.664.v4.1 with dh1025.1 antibody fab (23 kDa, Complex from Human immunodeficiency virus 2)
- Dh1025.1 antibody fab heavy chain (Protein from Macaca mulatta)
- Dh1025.1 antibody fab light chain (Protein from Macaca mulatta)
Cryo-EM structure of immature Zika virus in complex with human antibody DV62.5 Fab
Resolution: 8.0 Å
EM Method: Single-particle
Fitted PDBs: 6lnt
Q-score: 0.127
Tan TY, Fibriansah G, Kostyuchenko VA, Ng TS, Lim XX, Zhang S, Lim XN, Wang J, Shi J, Morais MC, Corti D, Lok SM
Nat Commun (2020) 11 pp. 895-895 [ DOI: doi:10.1038/s41467-020-14647-9 Pubmed: 32060358 ]
- Zika virus zikv/h. sapiens/frenchpolynesia/10087pf/2013 (Virus)
- Zika virus (Complex from Zika virus ZIKV/H. sapiens/FrenchPolynesia/10087PF/2013)
- Fab dv62.5 heavy-chain variable region (13 kDa, Protein from Homo sapiens)
- Envelope protein (54 kDa, Protein from Zika virus (isolate ZIKV/Human/French Polynesia/10087PF/2013))
- Fab dv62.5 light-chain variable region (11 kDa, Protein from Homo sapiens)
- Pre-membrane protein (18 kDa, Protein from Zika virus (isolate ZIKV/Human/French Polynesia/10087PF/2013))
- Anti-prm antibody dv62.5 (Complex from Homo sapiens)
- Capsid protein (12 kDa, Protein from Zika virus (isolate ZIKV/Human/French Polynesia/10087PF/2013))
Cryo-EM structure of HPV6 PsV in complex with the Fab fragment of antibody 17D5
Xu K, Acharya P, Kong R, Cheng C, Chuang GY, Liu K, Louder MK, O'Dell S, Rawi R, Sastry M, Shen CH, Zhang B, Zhou T, Asokan M, Bailer RT, Chambers M, Chen X, Choi CW, Dandey VP, Doria-Rose NA, Druz A, Eng ET, Farney SK, Foulds KE, Geng H, Georgiev IS, Gorman J, Hill KR, Jafari AJ, Kwon YD, Lai YT, Lemmin T, McKee K, Ohr TY, Ou L, Peng D, Rowshan AP, Sheng Z, Todd JP, Tsybovsky Y, Viox EG, Wang Y, Wei H, Yang Y, Zhou AF, Chen R, Yang L, Scorpio DG, McDermott AB, Shapiro L, Carragher B, Potter CS, Mascola JR, Kwong PD
Nat Med (2018) 24 pp. 857-867 [ Pubmed: 29867235 DOI: doi:10.1038/s41591-018-0042-6 ]
- Bg505 ds-sosip (Protein from Human immunodeficiency virus 1)
- Hiv-1 env trimer in complex with antibody (Complex from Human immunodeficiency virus 1)
- Vfp1.01 light chain (Protein from Homo sapiens)
- Hiv-1 env trimer (Complex from Human immunodeficiency virus 1)
- Vfp1.01 heavy chain (Protein from Homo sapiens)
MERS S ectodomain trimer in complex with Fab of neutralizing antibody G4
Pallesen J, Wang N, Corbett KS, Wrapp D, Kirchdoerfer RN, Turner HL, Cottrell CA, Becker MM, Wang L, Shi W, Kong WP, Andres EL, Kettenbach AN, Denison MR, Chappell JD, Graham BS, Ward AB, McLellan JS
PNAS (2017) 114 pp. E7348-E7357 [ DOI: doi:10.1073/pnas.1707304114 Pubmed: 28807998 ]
Zika virus complexed with a neutralizing antibody Z23-Fab
Resolution: 9.4 Å
EM Method: Single-particle
Fitted PDBs: 5gzr
Q-score: 0.102
Wang Q, Yang H, Liu X, Dai L, Ma T, Qi J, Wong G, Peng R, Liu S, Li J, Li S, Song J, Liu J, He J, Yuan H, Xiong Y, Liao Y, Li J, Yang J, Tong Z, Griffin BD, Bi Y, Liang M, Xu X, Qin C, Cheng G, Zhang X, Wang P, Qiu X, Kobinger G, Shi Y, Yan J, Gao GF
Sci Transl Med (2016) 8 pp. 369ra179-369ra179 [ DOI: doi:10.1126/scitranslmed.aai8336 Pubmed: 27974667 ]
- Structural protein e (54 kDa, Protein from Zika virus)
- Zika virus (Complex from Zika virus)
- Z23 fab light chain (23 kDa, Protein from Homo sapiens)
- Z23 fab heavy chain (23 kDa, Protein from Homo sapiens)
- Strutural protein m (8 kDa, Protein from Zika virus)
- Neutralizing antibody z23 fab (Complex)
- Zika virus in complex with a neutralizing antibody z23 fab (Complex)
Fibriansah G, Ibarra KD, Ng TS, Smith SA, Tan JL, Lim XN, Ooi JSG, Kostyuchenko VA, Wang J, de Silva AM, Harris E, Crowe JE, Lok SM
Science (2015) 349 pp. 88-91 [ Pubmed: 26138979 DOI: doi:10.1126/science.aaa8651 ]
Dengue virus serotype 2 with Fab fragments of human antibody B7
Dejnirattisai W, Wongwiwat W, Supasa S, Zhang X, Dai X, Rouvinski A, Rouvinsky A, Jumnainsong A, Edwards C, Quyen NT, Duangchinda T, Grimes JM, Tsai WY, Lai CY, Wang WK, Malasit P, Farrar J, Simmons CP, Zhou ZH, Rey FA, Mongkolsapaya J, Screaton GR
Nat Immunol (2015) 16 pp. 170-177 [ Pubmed: 25501631 DOI: doi:10.1038/ni.3058 ]