Resolution: 4.17 Å
EM Method: Single-particle
Fitted PDBs: 8dul
Q-score: 0.241
Sutton MS, Pletnev S, Callahan V, Ko S, Tsybovsky Y, Bylund T, Casner RG, Cerutti G, Gardner CL, Guirguis V, Verardi R, Zhang B, Ambrozak D, Beddall M, Lei H, Yang ES, Liu T, Henry AR, Rawi R, Schon A, Schramm CA, Shen CH, Shi W, Stephens T, Yang Y, Florez MB, Ledgerwood JE, Burke CW, Shapiro L, Fox JM, Kwong PD, Roederer M
Cell (2023) 186 pp. 2672-2689.e25 [ Pubmed: 37295404 DOI: doi:10.1016/j.cell.2023.05.019 ]
- Spike glycoprotein e1 (52 kDa, Protein from Western equine encephalitis virus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Spike glycoprotein e2 (45 kDa, Protein from Western equine encephalitis virus)
- Antibody fab skt05 heavy chain (25 kDa, Protein from Macaca fascicularis)
- Western equine encephalitis virus trimer in complex with antibody fab skt05 (Complex from Western equine encephalitis virus)
- Antibody fab skt05 light chain (23 kDa, Protein from Macaca fascicularis)
Resolution: 4.8 Å
EM Method: Single-particle
Fitted PDBs: 7u0d
Q-score: 0.236
Zhou T, Wang L, Misasi J, Pegu A, Zhang Y, Harris DR, Olia AS, Talana CA, Yang ES, Chen M, Choe M, Shi W, Teng IT, Creanga A, Jenkins C, Leung K, Liu T, Stancofski ED, Stephens T, Zhang B, Tsybovsky Y, Graham BS, Mascola JR, Sullivan NJ, Kwong PD
Science (2022) 376 pp. eabn8897-eabn8897 [ Pubmed: 35324257 DOI: doi:10.1126/science.abn8897 ]
- Heavy chain of sars-cov-2 antibody a19-46.1 (24 kDa, Protein from Homo sapiens)
- Ternary complex of sars-cov-2 omicron rbd in complex with antibodies b1-182.1 and a19-46.1 (Complex from Homo sapiens)
- Heavy chain of sars-cov-2 antibody b1-182.1 (24 kDa, Protein from Homo sapiens)
- Light chain of sars-cov-2 antibody b1-182.1 (23 kDa, Protein from Homo sapiens)
- Light chain of sars-cov-2 antibody a19-46.1 (22 kDa, Protein from Homo sapiens)
- Surface glycoprotein (22 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Cryo-EM structure of HIV-1 Env trimer BG505 SOSIP.664 in complex with CD4bs antibody Ab1573
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 7tfo
Q-score: 0.359
Yang Z, Dam KA, Bridges MD, Hoffmann MAG, DeLaitsch AT, Gristick HB, Escolano A, Gautam R, Martin MA, Nussenzweig MC, Hubbell WL, Bjorkman PJ
Nat Commun (2022) 13 pp. 732-732 [ DOI: doi:10.1038/s41467-022-28424-3 Pubmed: 35136084 ]
- Bg505 sosip.664 in complex with cd4bs antibody ab1573 (Complex from Macaca mulatta)
- Envelope glycoprotein bg505 sosip.664 - gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- Envelope glycoprotein bg505 sosip.664 - gp120 (54 kDa, Protein from Human immunodeficiency virus 1)
- Cd4 binding site antibody ab1573 - fab heavy chain (24 kDa, Protein from Macaca mulatta)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Cd4 binding site antibody ab1573 - fab light chain (23 kDa, Protein from Macaca mulatta)
Cryo-EM structure of CD4bs antibody Ab1303 in complex with HIV-1 Env trimer BG505 SOSIP.664
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 7tfn
Q-score: 0.437
Yang Z, Dam KA, Bridges MD, Hoffmann MAG, DeLaitsch AT, Gristick HB, Escolano A, Gautam R, Martin MA, Nussenzweig MC, Hubbell WL, Bjorkman PJ
Nat Commun (2022) 13 pp. 732-732 [ DOI: doi:10.1038/s41467-022-28424-3 Pubmed: 35136084 ]
- Cd4 binding site antibody fab ab1303 - light chain (23 kDa, Protein from Macaca mulatta)
- Alpha-d-mannopyranose (180 Da, Ligand)
- Envelope glycoprotein bg505 sosip.664 - gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- Envelope glycoprotein bg505 sosip.664 - gp120 (54 kDa, Protein from Human immunodeficiency virus 1)
- Anti-hiv-1 cd4bs antibody fab ab1303 - heavy chain (25 kDa, Protein from Macaca mulatta)
- Cryo-em map of ab1303 in complex with bg505 sosip.664 env trimer (local resolution refined) (Complex from Human immunodeficiency virus 1)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 7li7
Q-score: 0.364
Sci Adv (2021) 7 pp. eabl3857-eabl3857 [ Pubmed: 34851672 DOI: doi:10.1126/sciadv.abl3857 ]
- Pentane (72 Da, Ligand)
- Dodecane (170 Da, Ligand)
- Variable domain of 15b8 antibody fab heavy chain (12 kDa, Protein from Mus musculus)
- Sodium-dependent serotonin transporter (60 kDa, Protein from Homo sapiens)
- Heptane (100 Da, Ligand)
- Variable domain of 15b8 antibody fab light chain (11 kDa, Protein from Mus musculus)
- Cholesterol (386 Da, Ligand)
- Decane (142 Da, Ligand)
- Apo human serotonin transporter in complex with 15b8 fab in nacl (Complex from Homo sapiens)
Structure of human SARS-CoV-2 neutralizing antibody C1C-A3 Fab
Resolution: 4.3 Å
EM Method: Single-particle
Fitted PDBs: 7sn2
Q-score: 0.399
Nabel KG, Clark SA, Shankar S, Pan J, Clark LE, Yang P, Coscia A, McKay LGA, Varnum HH, Brusic V, Tolan NV, Zhou G, Desjardins M, Turbett SE, Kanjilal S, Sherman AC, Dighe A, LaRocque RC, Ryan ET, Tylek C, Cohen-Solal JF, Darcy AT, Tavella D, Clabbers A, Fan Y, Griffiths A, Correia IR, Seagal J, Baden LR, Charles RC, Abraham J
Science (2022) 375 pp. eabl6251-eabl6251 [ DOI: doi:10.1126/science.abl6251 Pubmed: 34855508 ]
- Neutralizing antibody c1c-a3 fab light chain (25 kDa, Protein from Homo sapiens)
- Sars-cov-2_hexapro in complex with neutralizing antibody c1c-a3 fab from human patient (50 kDa, Complex from Severe acute respiratory syndrome coronavirus 2)
- C1c-a3 fab (Complex from Homo sapiens)
- Spike glycoprotein (141 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Neutralizing antibody c1c-a3 fab heavy chain (27 kDa, Protein from Homo sapiens)
- Sars-cov-2 spike protein sars-cov-2 hexapro (Complex from Severe acute respiratory syndrome coronavirus 2)
Cryo-EM structure of Gi-bound metabotropic glutamate receptor mGlu4
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 7e9h
Q-score: 0.303
Lin S, Han S, Cai X, Tan Q, Zhou K, Wang D, Wang X, Du J, Yi C, Chu X, Dai A, Zhou Y, Chen Y, Zhou Y, Liu H, Liu J, Yang D, Wang MW, Zhao Q, Wu B
Nature (2021) 594 pp. 583-588 [ DOI: doi:10.1038/s41586-021-03495-2 Pubmed: 34135510 ]
- Guanine nucleotide-binding protein g(i) subunit alpha-3 (40 kDa, Protein from Homo sapiens)
- Complex of mglu4 homodimer with heterotrimeric gi3 protein in presence of antibody (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Metabotropic glutamate receptor 4 (99 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (38 kDa, Protein from Homo sapiens)
- Phosphoserine (185 Da, Ligand)
- Scfv16 (27 kDa, Protein from Homo sapiens)
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 6vrk
Q-score: 0.336
Coleman JA, Navratna V, Antermite D, Yang D, Bull JA, Gouaux E
eLife (2020) 9 [ Pubmed: 32618269 DOI: doi:10.7554/eLife.56427 ]
- 8b6 antibody (Complex from Mus musculus)
- Serotonin transporter (Complex from Homo sapiens)
- 8b6 antibody, heavy chain (23 kDa, Protein from Mus musculus)
- Serotonin transporter 8b6 fab complex (105 kDa, Complex)
- Br-paroxetine (390 Da, Ligand)
- 8b6 antibody, light chain (23 kDa, Protein from Mus musculus)
- Sodium-dependent serotonin transporter (70 kDa, Protein from Homo sapiens)
- Dodecyl-beta-d-maltoside (510 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 6dzv
Q-score: 0.207
Coleman JA, Yang D, Zhao Z, Wen PC, Yoshioka C, Tajkhorshid E, Gouaux E
Nature (2019) 569 pp. 141-145 [ DOI: doi:10.1038/s41586-019-1135-1 Pubmed: 31019304 ]
- 15b8 antibody heavy chain (12 kDa, Protein from Mus musculus)
- Serotonin transporter (Complex from Homo sapiens)
- 15b8 fab (Complex from Mus musculus)
- Cholesterol hemisuccinate (486 Da, Ligand)
- Sodium-dependent serotonin transporter (60 kDa, Protein from Homo sapiens)
- Ibogaine-bound wild type human serotonin transporter in complex with 15b8 fab (Complex)
- (5beta)-12-methoxyibogamine (310 Da, Ligand)
- 15b8 antibody light chain (11 kDa, Protein from Mus musculus)
Resolution: 4.3 Å
EM Method: Single-particle
Fitted PDBs: 6dzw
Q-score: 0.174
Coleman JA, Yang D, Zhao Z, Wen PC, Yoshioka C, Tajkhorshid E, Gouaux E
Nature (2019) 569 pp. 141-145 [ DOI: doi:10.1038/s41586-019-1135-1 Pubmed: 31019304 ]
- Human serotonin transporter in complex with fab/fv bound to paroxetine (Complex)
- 15b8 antibody heavy chain (12 kDa, Protein from Mus musculus)
- Serotonin transporter (Complex from Homo sapiens)
- 15b8 fab (Complex from Mus musculus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Paroxetine (329 Da, Ligand)
- Sodium-dependent serotonin transporter (60 kDa, Protein from Homo sapiens)
- 8b6 antibody single chain (26 kDa, Protein from Mus musculus)
- 15b8 antibody light chain (11 kDa, Protein from Mus musculus)
- 8b6 scfv (Complex from Mus musculus)