Rujas E, Kucharska I, Tan YZ, Benlekbir S, Cui H, Zhao T, Wasney GA, Budylowski P, Guvenc F, Newton JC, Sicard T, Semesi A, Muthuraman K, Nouanesengsy A, Aschner CB, Prieto K, Bueler SA, Youssef S, Liao-Chan S, Glanville J, Christie-Holmes N, Mubareka S, Gray-Owen SD, Rubinstein JL, Treanor B, Julien JP
Nat Commun (2021) 12 pp. 3661-3661 [ DOI: doi:10.1038/s41467-021-23825-2 Pubmed: 34135340 ]
- Fab 46 heavy chain (Protein from Homo sapiens)
- Fab 46 light chain (Protein from Homo sapiens)
- Receptor binding domain of sars-cov-2 spike (Protein from Severe acute respiratory syndrome coronavirus 2)
- Fab fragment of neutralizing antibody 46 (Complex from Homo sapiens)
- Sars-cov-2 receptor binding domain (Complex from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2 receptor binding domain in complex with the fab fragment of neutralizing antibody 46 (Complex)
Rujas E, Kucharska I, Tan YZ, Benlekbir S, Cui H, Zhao T, Wasney GA, Budylowski P, Guvenc F, Newton JC, Sicard T, Semesi A, Muthuraman K, Nouanesengsy A, Aschner CB, Prieto K, Bueler SA, Youssef S, Liao-Chan S, Glanville J, Christie-Holmes N, Mubareka S, Gray-Owen SD, Rubinstein JL, Treanor B, Julien JP
Nat Commun (2021) 12 pp. 3661-3661 [ DOI: doi:10.1038/s41467-021-23825-2 Pubmed: 34135340 ]
- Fab 80 light chain (Protein from Homo sapiens)
- Fab fragment of neutralizing antibody 80 (Complex from Homo sapiens)
- Sars-cov-2 spike in complex with the fab fragment of neutralizing antibody 80 (Complex)
- Sars-cov-2 spike (Complex from Severe acute respiratory syndrome coronavirus 2)
- Fab 80 heavy chain (Protein from Homo sapiens)
- Sars-cov-2 spike (Protein from Severe acute respiratory syndrome coronavirus 2)
Rujas E, Kucharska I, Tan YZ, Benlekbir S, Cui H, Zhao T, Wasney GA, Budylowski P, Guvenc F, Newton JC, Sicard T, Semesi A, Muthuraman K, Nouanesengsy A, Aschner CB, Prieto K, Bueler SA, Youssef S, Liao-Chan S, Glanville J, Christie-Holmes N, Mubareka S, Gray-Owen SD, Rubinstein JL, Treanor B, Julien JP
Nat Commun (2021) 12 pp. 3661-3661 [ DOI: doi:10.1038/s41467-021-23825-2 Pubmed: 34135340 ]
- Fab fragment of neutralizing antibody 298 (Complex from Homo sapiens)
- Sars-cov-2 spike in complex with the fab fragment of neutralizing antibody 298 (Complex)
- Fab 298 heavy chain (Protein from Homo sapiens)
- Fab 298 light chain (Protein from Homo sapiens)
- Sars-cov-2 spike (Complex from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2 spike (Protein from Severe acute respiratory syndrome coronavirus 2)
Rujas E, Kucharska I, Tan YZ, Benlekbir S, Cui H, Zhao T, Wasney GA, Budylowski P, Guvenc F, Newton JC, Sicard T, Semesi A, Muthuraman K, Nouanesengsy A, Aschner CB, Prieto K, Bueler SA, Youssef S, Liao-Chan S, Glanville J, Christie-Holmes N, Mubareka S, Gray-Owen SD, Rubinstein JL, Treanor B, Julien JP
Nat Commun (2021) 12 pp. 3661-3661 [ DOI: doi:10.1038/s41467-021-23825-2 Pubmed: 34135340 ]
- Fab 324 light chain (Protein from Homo sapiens)
- Sars-cov-2 spike in complex with the fab fragment of neutralizing antibody 324 (Complex)
- Sars-cov-2 spike (Complex from Severe acute respiratory syndrome coronavirus 2)
- Fab 324 heavy chain (Protein from Homo sapiens)
- Sars-cov-2 spike (Protein from Severe acute respiratory syndrome coronavirus 2)
- Fab fragment of neutralizing antibody 324 (Complex from Homo sapiens)
BG505 SOSIP.664 trimer in complex with broadly neutralizing HIV antibodies 3BNC117 and PGT145
Resolution: 4.3 Å
EM Method: Single-particle
Fitted PDBs: 5v8l
Q-score: 0.346
Lee JH, Andrabi R, Su CY, Yasmeen A, Julien JP, Kong L, Wu NC, McBride R, Sok D, Pauthner M, Cottrell CA, Nieusma T, Blattner C, Paulson JC, Klasse PJ, Wilson IA, Burton DR, Ward AB
Immunity (2017) 46 pp. 690-702 [ DOI: doi:10.1016/j.immuni.2017.03.017 Pubmed: 28423342 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Gp120 (54 kDa, Protein from Human immunodeficiency virus 1)
- Bg505 sosip.664 trimer in complex with pgt145 and 3bnc117 fabs (560 kDa, Complex from Human immunodeficiency virus 1)
- 3bnc117 antibody, light chain (23 kDa, Protein from Homo sapiens)
- Pgt145 antibody, heavy chain (28 kDa, Protein from Homo sapiens)
- Pgt145 antibody, light chain (23 kDa, Protein from Homo sapiens)
- 3bnc117 antibody, heavy chain (24 kDa, Protein from Homo sapiens)
- Gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
BG505 SOSIP.664 trimer in complex with broadly neutralizing HIV antibody 3BNC117
Resolution: 4.4 Å
EM Method: Single-particle
Fitted PDBs: 5v8m
Q-score: 0.347
Lee JH, Andrabi R, Su CY, Yasmeen A, Julien JP, Kong L, Wu NC, McBride R, Sok D, Pauthner M, Cottrell CA, Nieusma T, Blattner C, Paulson JC, Klasse PJ, Wilson IA, Burton DR, Ward AB
Immunity (2017) 46 pp. 690-702 [ DOI: doi:10.1016/j.immuni.2017.03.017 Pubmed: 28423342 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Bg505 sosip.664 soluble env trimer in complex with 3bnc117 fab (510 kDa, Complex from Homo sapiens)
- Antibody 3bnc117, light chain (23 kDa, Protein from Homo sapiens)
- Gp120 (54 kDa, Protein from Human immunodeficiency virus 1)
- Antibody 3bnc117, heavy chain (24 kDa, Protein from Homo sapiens)
- Gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
Negative stain Electron Microscopy of BG505 SOSIP.664 gp140 in complex with PGV04
Sanders RW, Derking R, Cupo A, Julien JP, Yasmeen A, de Val N, Kim HJ, Blattner C, Torrents A, Korzun J, Golabek M, de los Reyes K, Ketas TJ, van Gils MJ, King CR, Wilson IA, Ward AB, Klasse PJ, Moore JP
PLoS Pathog (2013) 9 pp. e1003618-e1003618 [ Pubmed: 24068931 DOI: doi:10.1371/journal.ppat.1003618 ]
Negative stain Electron Microscopy of Bg505 SOSIP.664 in complex with sCD4 and 17b
Sanders RW, Derking R, Cupo A, Julien JP, Yasmeen A, de Val N, Kim HJ, Blattner C, de la Pena AT, Korzun J, Golabek M, de Los Reyes K, Ketas TJ, van Gils MJ, King CR, Wilson IA, Ward AB, Klasse PJ, Moore JP
PLoS Pathog (2013) 9 pp. e1003618-e1003618 [ Pubmed: 24068931 DOI: doi:10.1371/journal.ppat.1003618 ]
- Hiv spike protein 664g construct in complex with scd4 and fab fragment of 17b monoclonal antibody (570 kDa, Sample)
- Scd4 (Protein from Escherichia coli)
- 17b fab (Protein from Cricetulus griseus)
- Hiv spike protein bg505 sosip.664 (360 kDa, Protein from Human immunodeficiency virus)