Electron Microscopy Data Bank

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Cryo-EM structure of Dengue virus serotype 1 strain WestPac 74 in complex with human antibody 1C19 Fab at 37 deg C (Class 1 particle)

Release date: Feb. 17, 2021
Resolution: 19.0 Å
EM Method: Single-particle
Fitted PDBs: 7dwt
Q-score: 0.022

Fibriansah G, Lim EXY, Marzinek JK, Ng TS, Tan JL, Huber RG, Lim XN, Chew VSY, Kostyuchenko VA, Shi J, Anand GS, Bond PJ, Crowe Jr JE, Lok SM

PLoS Pathog (2021) 17 pp. e1009331-e1009331 [ Pubmed: 33621239 DOI: doi:10.1371/journal.ppat.1009331 ]

Sample:

Anti-dengue virus human monoclonal antibody 1c19 fab light chain (11 kDa, Protein from Homo sapiens)
Antibody 1c19 fab (Complex)
Dengue virus serotype 1 strain westpac 74 in complex with human antibody 1c19 fab (Complex from Dengue virus 1)
Anti-dengue virus human monoclonal antibody 1c19 fab heavy chain (13 kDa, Protein from Homo sapiens)
Dengue virus 1 (Complex from Homo sapiens)
Envelope protein (53 kDa, Protein from Dengue virus 1)

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EMD-30884

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Cryo-EM structure of Dengue virus serotype 1 strain WestPac 74 in complex with human antibody 1C19 Fab at 37 deg C (Class 2 particle)

Release date: Feb. 17, 2021
Resolution: 19.0 Å
EM Method: Single-particle
Fitted PDBs: 7dwu
Q-score: 0.021

Fibriansah G, Lim EXY, Marzinek JK, Ng TS, Tan JL, Huber RG, Lim XN, Chew VSY, Kostyuchenko VA, Shi J, Anand GS, Bond PJ, Crowe Jr JE, Lok SM

PLoS Pathog (2021) 17 pp. e1009331-e1009331 [ Pubmed: 33621239 DOI: doi:10.1371/journal.ppat.1009331 ]

Sample:

Anti-dengue virus human monoclonal antibody 1c19 fab light chain (11 kDa, Protein from Homo sapiens)
Antibody 1c19 fab (Complex)
Dengue virus 1 (Complex from Dengue virus 1)
Anti-dengue virus human monoclonal antibody 1c19 fab heavy chain (13 kDa, Protein from Homo sapiens)
Dengue virus 1 (Complex from Homo sapiens)
Envelope protein (53 kDa, Protein from Dengue virus 1)

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EMD-30885

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Cryo-EM map of Dengue virus serotype 2 strain PVP94/07 in complex with human antibody 1C19 Fab at 37 deg C

Release date: Feb. 17, 2021
Resolution: 23.0 Å
EM Method: Single-particle

Fibriansah G, Lim EXY, Marzinek JK, Ng TS, Tan JL, Huber RG, Lim XN, Chew VSY, Kostyuchenko VA, Shi J, Anand GS, Bond PJ, Crowe Jr JE, Lok SM

PLoS Pathog (2021) 17 pp. e1009331-e1009331 [ Pubmed: 33621239 DOI: doi:10.1371/journal.ppat.1009331 ]

Sample:

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EMD-30886

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Cryo-EM map of Dengue virus serotype 2 strain PVP94/07 in complex with human antibody 1C19 Fab at 40 deg C

Release date: Feb. 17, 2021
Resolution: 23.0 Å
EM Method: Single-particle

Fibriansah G, Lim EXY, Marzinek JK, Ng TS, Tan JL, Huber RG, Lim XN, Chew VSY, Kostyuchenko VA, Shi J, Anand GS, Bond PJ, Crowe Jr JE, Lok SM

PLoS Pathog (2021) 17 pp. e1009331-e1009331 [ Pubmed: 33621239 DOI: doi:10.1371/journal.ppat.1009331 ]

Sample:

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EMD-2967

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Cryo-EM structure of Dengue virus serotype 2 in complex with antigen-binding fragments of human antibody 2D22

Release date: July 15, 2015
Resolution: 6.5 Å
EM Method: Single-particle
Fitted PDBs: 4uif
Q-score: 0.188

Fibriansah G, Ibarra KD, Ng TS, Smith SA, Tan JL, Lim XN, Ooi JSG, Kostyuchenko VA, Wang J, de Silva AM, Harris E, Crowe JE, Lok SM

Science (2015) 349 pp. 88-91 [ Pubmed: 26138979 DOI: doi:10.1126/science.aaa8651 ]

Sample:

EMD-2968

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Cryo-EM structure of Dengue virus serotype 2 strain New Guinea-C complexed with human antibody 2D22 Fab at 37 degree C. The Fab molecules were added to the virus before 37 degree C incubation.

Release date: July 15, 2015
Resolution: 20.0 Å
EM Method: Single-particle
Fitted PDBs: 4uih
Q-score: 0.016

Fibriansah G, Ibarra KD, Ng TS, Smith SA, Tan JL, Lim XN, Ooi JSG, Kostyuchenko VA, Wang J, de Silva AM, Harris E, Crowe JE, Lok SM

Science (2015) 349 pp. 88-91 [ Pubmed: 26138979 DOI: doi:10.1126/science.aaa8651 ]

Sample:

EMD-2969

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Cryo-EM structure of Dengue virus serotype 2 strain New Guinea-C complexed with human antibody 2D22 Fab at 37 degree C. The Fab molecules were added to virus that was pre-incubated at 37 degree C.

Release date: July 15, 2015
Resolution: 21.0 Å
EM Method: Single-particle

Fibriansah G, Ibarra KD, Ng TS, Smith SA, Tan JL, Lim XN, Ooi JSG, Kostyuchenko VA, Wang J, de Silva AM, Harris E, Crowe JE, Lok SM

Science (2015) 349 pp. 88-91 [ Pubmed: 26138979 DOI: doi:10.1126/science.aaa8651 ]

Sample:

EMD-2996

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Cryo-EM structure of Dengue virus serotype 2 strain PVP94/07 complexed with human antibody 2D22 Fab at 37 degrees C

Release date: July 15, 2015
Resolution: 6.9 Å
EM Method: Single-particle
Fitted PDBs: 5a1z
Q-score: 0.21

Fibriansah G, Ibarra KD, Ng TS, Smith SA, Tan JL, Lim XN, Ooi JSG, Kostyuchenko VA, Wang J, de Silva AM, Harris E, Crowe JE, Lok SM

Science (2015) 349 pp. 88-91 [ Pubmed: 26138979 DOI: doi:10.1126/science.aaa8651 ]

Sample:

EMD-2997

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Cryo-EM structure of Dengue virus serotype 2 strain New Guinea-C complexed with human antibody 2D22 Fab at 4 degrees C

Release date: July 15, 2015
Resolution: 13.0 Å
EM Method: Single-particle

Fibriansah G, Ibarra KD, Ng TS, Smith SA, Tan JL, Lim XN, Ooi JSG, Kostyuchenko VA, Wang J, de Silva AM, Harris E, Crowe JE, Lok SM

Science (2015) 349 pp. 88-91 [ Pubmed: 26138979 DOI: doi:10.1126/science.aaa8651 ]

Sample:

EMD-2998

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Cryo-EM structure of the unexpanded particles of Dengue virus serotype 2 strain New Guinea-C in complex with human antibody 2D22 Fab at 37 degrees C. The Fab molecules were added to the virus that had been pre-incubated at 37 degrees C.

Release date: July 15, 2015
Resolution: 11.0 Å
EM Method: Single-particle

Fibriansah G, Ibarra KD, Ng TS, Smith SA, Tan JL, Lim XN, Ooi JSG, Kostyuchenko VA, Wang J, de Silva AM, Harris E, Crowe JE, Lok SM

Science (2015) 349 pp. 88-91 [ Pubmed: 26138979 DOI: doi:10.1126/science.aaa8651 ]

Sample:

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