Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 7kcr
Q-score: 0.436
Sevvana M, Rogers TF, Miller AS, Long F, Klose T, Beutler N, Lai YC, Parren M, Walker LM, Buda G, Burton DR, Rossmann MG, Kuhn RJ
Viruses (2020) 12 [ Pubmed: 33255202 DOI: doi:10.3390/v12121346 ]
- Adi30056 fab heavy chain variable region (13 kDa, Protein from Homo sapiens)
- Envelope protein e (54 kDa, Protein from Zika virus ZIKV/H. sapiens/FrenchPolynesia/10087PF/2013)
- Zika virus zikv/h. sapiens/frenchpolynesia/10087pf/2013 (Virus from Zika virus ZIKV/H. sapiens/FrenchPolynesia/10087PF/2013)
- Monoclonal antibody adi30056 (Complex from Homo sapiens)
- Zika virus in complex with monoclonal antibody adi30056 (15 MDa, Complex)
- Adi30056 fab light chain variable region (11 kDa, Protein from Homo sapiens)
- Membrane protein m (8 kDa, Protein from Zika virus ZIKV/H. sapiens/FrenchPolynesia/10087PF/2013)
Enterovirus D68 in complex with human monoclonal antibody EV68-159
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 6wds
Q-score: 0.631
Vogt MR, Fu J, Kose N, Williamson LE, Bombardi R, Setliff I, Georgiev IS, Klose T, Rossmann MG, Bochkov YA, Gern JE, Kuhn RJ, Crowe Jr JE
Sci Immunol (2020) 5 [ Pubmed: 32620559 DOI: doi:10.1126/sciimmunol.aba4902 ]
- Viral protein 4 (7 kDa, Protein from Enterovirus D68)
- Viral protein 3 (27 kDa, Protein from Enterovirus D68)
- Viral protein 1 (32 kDa, Protein from Enterovirus D68)
- Viral protein 2 (27 kDa, Protein from Enterovirus D68)
- Ev68-159 heavy chain (13 kDa, Protein from Homo sapiens)
- Enterovirus d68 in complex with human monoclonal antibody ev68-159 (Complex)
- Enterovirus d68 (Virus from Enterovirus D68)
- Human antibody ev68-159 (Complex from Homo sapiens)
- Ev68-159 light chain (11 kDa, Protein from Homo sapiens)
Enterovirus D68 in complex with human monoclonal antibody EV68-228
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 6wdt
Q-score: 0.589
Vogt MR, Fu J, Kose N, Williamson LE, Bombardi R, Setliff I, Georgiev IS, Klose T, Rossmann MG, Bochkov YA, Gern JE, Kuhn RJ, Crowe Jr JE
Sci Immunol (2020) 5 [ Pubmed: 32620559 DOI: doi:10.1126/sciimmunol.aba4902 ]
- Viral protein 4 (7 kDa, Protein from Enterovirus D68)
- Ev68-228 light chain (11 kDa, Protein from Homo sapiens)
- Enterovirus d68 in complex with human monoclonal antibody ev68-228 (Complex)
- Viral protein 3 (27 kDa, Protein from Enterovirus D68)
- Viral protein 1 (32 kDa, Protein from Enterovirus D68)
- Viral protein 2 (27 kDa, Protein from Enterovirus D68)
- Enterovirus d68 (Virus from Enterovirus D68)
- Human monoclonal antibody ev68-228 (Complex from Homo sapiens)
- Ev68-228 heavy chain (14 kDa, Protein from Homo sapiens)
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 6mid
Q-score: 0.451
Long F, Doyle M, Fernandez E, Miller AS, Klose T, Sevvana M, Bryan A, Davidson E, Doranz BJ, Kuhn RJ, Diamond MS, Crowe Jr JE, Rossmann MG
PNAS (2019) 116 pp. 1591-1596 [ DOI: doi:10.1073/pnas.1815432116 Pubmed: 30642974 ]
- Zika virus (isolate zikv/human/french polynesia/10087pf/2013) (Virus from Zika virus (isolate ZIKV/Human/French Polynesia/10087PF/2013))
- Zikv virion in complex with fab fragments of the potently neutralizing human monoclonal antibody zikv-195 (Complex)
- M protein (8 kDa, Protein from Zika virus (isolate ZIKV/Human/French Polynesia/10087PF/2013))
- Monoclonal antibody zikv-195 light chain (11 kDa, Protein from Homo sapiens)
- E protein (54 kDa, Protein from Zika virus (isolate ZIKV/Human/French Polynesia/10087PF/2013))
- Monoclonal antibody zikv-195 (Complex from Homo sapiens)
- Monoclonal antibody zikv-195 heavy chain (14 kDa, Protein from Homo sapiens)
CryoEM structure of chimeric Eastern Equine Encephalitis Virus with Fab of EEEV-42 antibody
Resolution: 7.7 Å
EM Method: Single-particle
Fitted PDBs: 6mui
Q-score: 0.075
Hasan SS, Sun C, Kim AS, Watanabe Y, Chen CL, Klose T, Buda G, Crispin M, Diamond MS, Klimstra WB, Rossmann MG
Cell Rep (2018) 25 pp. 3136-3147.e5 [ Pubmed: 30540945 DOI: doi:10.1016/j.celrep.2018.11.067 ]
- E2 (53 kDa, Protein from Eastern equine encephalitis virus)
- Eeev-42 fab (Complex from Mus musculus)
- Eeev-42 antibody heavy chain (23 kDa, Protein from Mus musculus)
- Eastern equine encephalitis virus (Virus from Eastern equine encephalitis virus)
- E1 (47 kDa, Protein from Eastern equine encephalitis virus)
- Eeev-42 antibody light chain (23 kDa, Protein from Mus musculus)
- Eastern equine encephalitis virus / eeev-42 fab complex (Complex)
CryoEM structure of chimeric Eastern Equine Encephalitis Virus with Fab of EEEV-3 antibody
Resolution: 7.3 Å
EM Method: Single-particle
Fitted PDBs: 6mw9
Q-score: 0.097
Hasan SS, Sun C, Kim AS, Watanabe Y, Chen CL, Klose T, Buda G, Crispin M, Diamond MS, Klimstra WB, Rossmann MG
Cell Rep (2018) 25 pp. 3136-3147.e5 [ Pubmed: 30540945 DOI: doi:10.1016/j.celrep.2018.11.067 ]
- Eeev-3 antibody light chain (23 kDa, Protein from Mus musculus)
- Eeev-3 antibody heavy chain (23 kDa, Protein from Mus musculus)
- Eastern equine encephalitis virus / eeev-3 fab complex (Complex)
- Eastern equine encephalitis virus (Complex from Eastern equine encephalitis virus)
- E1 (47 kDa, Protein from Eastern equine encephalitis virus)
- Eeev-3 fab (Complex from Mus musculus)
- E2 (47 kDa, Protein from Eastern equine encephalitis virus)
CryoEM structure of chimeric Eastern Equine Encephalitis Virus with Fab of EEEV-5 antibody
Resolution: 7.5 Å
EM Method: Single-particle
Fitted PDBs: 6mwc
Q-score: 0.087
Hasan SS, Sun C, Kim AS, Watanabe Y, Chen CL, Klose T, Buda G, Crispin M, Diamond MS, Klimstra WB, Rossmann MG
Cell Rep (2018) 25 pp. 3136-3147.e5 [ Pubmed: 30540945 DOI: doi:10.1016/j.celrep.2018.11.067 ]
- Eastern equine encephalitis virus / eeev-5 fab complex (Complex)
- Eeev-5 fab (Complex from Mus musculus)
- Eeev-5 antibody heavy chain (23 kDa, Protein from Mus musculus)
- Eastern equine encephalitis virus (Complex from Eastern equine encephalitis virus)
- E1 (47 kDa, Protein from Eastern equine encephalitis virus)
- E2 (47 kDa, Protein from Eastern equine encephalitis virus)
- Eeev-5 antibody light chain (23 kDa, Protein from Mus musculus)
CryoEM structure of Chimeric Eastern Equine Encephalitis Virus with Fab of EEEV-58 Antibody
Resolution: 7.3 Å
EM Method: Single-particle
Fitted PDBs: 6mwv
Q-score: 0.092
Hasan SS, Sun C, Kim AS, Watanabe Y, Chen CL, Klose T, Buda G, Crispin M, Diamond MS, Klimstra WB, Rossmann MG
Cell Rep (2018) 25 pp. 3136-3147.e5 [ Pubmed: 30540945 DOI: doi:10.1016/j.celrep.2018.11.067 ]
- Eeev-58 antibody light chain (23 kDa, Protein from Mus musculus)
- Eeev-58 antibody heavy chain (23 kDa, Protein from Mus musculus)
- E1 (47 kDa, Protein from Eastern equine encephalitis virus)
- Eastern equine encephalitis virus (Complex from Eastern equine encephalitis virus)
- Eastern equine encephalitis virus / eeev-58 fab complex (Complex)
- Eeev-58 fab (Complex from Mus musculus)
- E2 (47 kDa, Protein from Eastern equine encephalitis virus)
CryoEM structure of Chimeric Eastern Equine Encephalitis Virus with Fab of EEEV-69 Antibody
Resolution: 8.2 Å
EM Method: Single-particle
Fitted PDBs: 6mwx
Q-score: 0.084
Hasan SS, Sun C, Kim AS, Watanabe Y, Chen CL, Klose T, Buda G, Crispin M, Diamond MS, Klimstra WB, Rossmann MG
Cell Rep (2018) 25 pp. 3136-3147.e5 [ Pubmed: 30540945 DOI: doi:10.1016/j.celrep.2018.11.067 ]
- Eeev-69 fab (Complex from Mus musculus)
- E1 (47 kDa, Protein from Eastern equine encephalitis virus)
- Eastern equine encephalitis virus (Complex from Eastern equine encephalitis virus)
- Eeev-69 antibody light chain (23 kDa, Protein from Mus musculus)
- Eastern equine encephalitis virus / eeev-69 fab complex (Complex)
- E2 (47 kDa, Protein from Eastern equine encephalitis virus)
- Eeev-69 antibody heavy chain (23 kDa, Protein from Mus musculus)
Structure of parvovirus B19 decorated with Fab molecules from a human antibody
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 6nn3
Q-score: 0.521
Rossmann MG, Sun Y, Klose T, Liu Y, Meng G
To Be Published
- Antibody 860-55d light chain (10 kDa, Protein from Homo sapiens)
- Human parvovirus b19 (Virus from Human parvovirus B19)
- Antibody 860-55d fab (Complex from Homo sapiens)
- Antibody 860-55d heavy chain (11 kDa, Protein from Homo sapiens)
- Vp2 (60 kDa, Protein from Human parvovirus B19)
- Complex of b19 vlp with fab molecules of antibody 860-55d (5 MDa, Complex)