Integrin alpha-v beta-8 in complex with the Fab of 130H2
Resolution: 2.88 Å
EM Method: Single-particle
Fitted PDBs: 9ind
Q-score: 0.533
Guo C, Sun H, Du Y, Dai X, Pang Y, Han Z, Xiong X, Li S, Zhang J, Zheng Q, Gui X
J Exp Clin Cancer Res (2025) 44 pp. 1-1 [ DOI: doi:10.1186/s13046-024-03250-1 Pubmed: 39743547 ]
- Integrin alpha-v beta-8 complexed with antibody fab fragment of 130h2 (Complex)
- Integrin beta-8 (39 kDa, Protein from Homo sapiens)
- 130h2-fab (Complex from Mus musculus)
- The light chain of 130h2-fab (11 kDa, Protein from Mus musculus)
- Integrin alpha-v beta-8 (Complex from Homo)
- Integrin alpha-v heavy chain (47 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- The heavy chain of 130h2-fab (13 kDa, Protein from Mus musculus)
Cryo-EM structure of neutralizing antibody 8G3 in complex with BA.1 RBD
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 9js4
Q-score: 0.434
Liao Y, Ma H, Wang Z, Wang S, He Y, Chang Y, Zong H, Tang H, Wang L, Ke Y, Cai H, Li P, Tang J, Chen H, Drelich A, Peng BH, Hsu J, Tat V, Tseng CK, Song J, Yuan Y, Wu M, Liu J, Yue Y, Zhang X, Wang Z, Yang L, Li J, Ni X, Li H, Xiang Y, Bian Y, Zhang B, Yin H, Dimitrov DS, Gilly J, Han L, Jiang H, Xie Y, Zhu J
PNAS (2025) 122 pp. e2406659122-e2406659122 [ DOI: doi:10.1073/pnas.2406659122 Pubmed: 39908098 ]
- Light chain of 8g3 (23 kDa, Protein from Homo sapiens)
- Cryo-em structure of neutralizing antibody 8g3 in complex with ba.1 rbd (Complex from Severe acute respiratory syndrome coronavirus 2)
- Heavy chain of 8g3 (23 kDa, Protein from Homo heidelbergensis)
- Spike glycoprotein (137 kDa, Protein from Severe acute respiratory syndrome coronavirus)
Structure of mouse C5a-human C5aR1-Go complex
Resolution: 3.45 Å
EM Method: Single-particle
Fitted PDBs: 8jzp
Q-score: 0.438
Yadav MK, Yadav R, Maharana J, Sarma P, Banerjee R, Shukla AK, Gati C
To Be Published
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (Complex from Homo sapiens)
- Mouse c5a-human c5ar1-go complex (Complex)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Antibody fragment scfv16 (26 kDa, Protein from Mus musculus)
- C5a anaphylatoxin chemotactic receptor 1 (45 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (38 kDa, Protein from Homo sapiens)
- C5a anaphylatoxin (12 kDa, Protein from Mus musculus)
- Antibody fragment - scfv16 (Complex from Mus musculus)
- Complement c5a (Complex from Mus musculus)
- Guanine nucleotide-binding protein g(o) subunit alpha (27 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(o) subunit alpha (Complex from Homo sapiens)
- C5a anaphylatoxin chemotactic receptor 1 (Complex from Homo sapiens)
Resolution: 2.68 Å
EM Method: Single-particle
Fitted PDBs: 9ekf
Q-score: 0.597
Morano NC, Guo Y, Becker JE, Li Z, Yu J, Ho DD, Shapiro L, Kwong PD
Structure (2025) 33 pp. 228-233.e3 [ Pubmed: 39884273 DOI: doi:10.1016/j.str.2025.01.001 ]
- Fab 65c6 heavy chain (25 kDa, Protein from Homo sapiens)
- Fab 65c6 light chain (23 kDa, Protein from Homo sapiens)
- Hemagglutinin (65 kDa, Protein from Influenza A virus)
- Complex of hemagglutinin from h5n1 ha a/texas/37/2024 with antibody (360 kDa, Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Cryo-EM structure for the GPRC5D complexed with Talquetamab Fab
Jeong J, Park J, Young Mo G, Shin J, Cho Y
J Mol Biol (2024) 436 pp. 168748-168748 [ Pubmed: 39181182 DOI: doi:10.1016/j.jmb.2024.168748 ]
- Antibody (Complex from Mus musculus)
- Gpcr antibody complex (Complex)
- Talquetamab fab (anti-gprc5d) light chain (23 kDa, Protein from Mus musculus)
- G-protein coupled receptor family c group 5 member d (39 kDa, Protein from Homo sapiens)
- Gpcr (Complex from Homo sapiens)
- Cholesterol (386 Da, Ligand)
- Talquetamab fab (anti-gprc5d) heavy chain (25 kDa, Protein from Mus musculus)
State 2 of SARS-CoV-2 XBB Variant Spike protein trimer complexed with antibody PW5-5
Zhao X, Qiu T, Huang X, Mao Q, Wang Y, Qiao R, Li J, Mao T, Wang Y, Cun Y, Wang C, Luo C, Yoon C, Wang X, Li C, Cui Y, Zhao C, Li M, Chen Y, Cai G, Geng W, Hu Z, Cao J, Zhang W, Cao Z, Chu H, Sun L, Wang P
Cell Discov (2024) 10 pp. 14-14 [ Pubmed: 38320990 DOI: doi:10.1038/s41421-024-00648-1 ]
- Pw5-5 light chain (23 kDa, Protein from Homo sapiens)
- Sars spike protein (s) in complex with broadly neutralizing antibody pw5-5 (Complex from Severe acute respiratory syndrome coronavirus 2)
- Pw5-5 heavy chain (49 kDa, Protein from Homo sapiens)
- Spike glycoprotein (143 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
Structure of SARS-CoV Spike protein complexed with antibody PW5-5
Zhao X, Qiu T, Huang X, Mao Q, Wang Y, Qiao R, Li J, Mao T, Wang Y, Cun Y, Wang C, Luo C, Yoon C, Wang X, Li C, Cui Y, Zhao C, Li M, Chen Y, Cai G, Geng W, Hu Z, Cao J, Zhang W, Cao Z, Chu H, Sun L, Wang P
Cell Discov (2024) 10 pp. 14-14 [ Pubmed: 38320990 DOI: doi:10.1038/s41421-024-00648-1 ]
- Spike glycoprotein (131 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Sars spike protein (s) in complex with broadly neutralizing antibody pw5-5 (Complex from Severe acute respiratory syndrome coronavirus 2)
- Pw5-5 heavy chain (49 kDa, Protein from Homo sapiens)
- Pw5-5 light chain (23 kDa, Protein from Homo sapiens)
The local refined map of SARS-CoV-2 XBB Variant Spike protein complexed with antibody PW5-535
Zhao X, Qiu T, Huang X, Mao Q, Wang Y, Qiao R, Li J, Mao T, Wang Y, Cun Y, Wang C, Luo C, Yoon C, Wang X, Li C, Cui Y, Zhao C, Li M, Chen Y, Cai G, Geng W, Hu Z, Cao J, Zhang W, Cao Z, Chu H, Sun L, Wang P
Cell Discov (2024) 10 pp. 14-14 [ Pubmed: 38320990 DOI: doi:10.1038/s41421-024-00648-1 ]
- Spike glycoprotein (143 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Xbb spike protein (s) in complex with broadly neutralizing antibody pw5-5353 (Complex from Homo sapiens)
- Pw5-535 light chain (23 kDa, Protein from Homo sapiens)
- Pw5-535 heavy chain (49 kDa, Protein from Homo sapiens)
Trimer state of SARS-CoV Spike protein complexed with antibody PW5-535
Zhao X, Qiu T, Huang X, Mao Q, Wang Y, Qiao R, Li J, Mao T, Wang Y, Cun Y, Wang C, Luo C, Yoon C, Wang X, Li C, Cui Y, Zhao C, Li M, Chen Y, Cai G, Geng W, Hu Z, Cao J, Zhang W, Cao Z, Chu H, Sun L, Wang P
Cell Discov (2024) 10 pp. 14-14 [ Pubmed: 38320990 DOI: doi:10.1038/s41421-024-00648-1 ]
- Pw5-535 light chain (23 kDa, Protein from Homo sapiens)
- Sars spike protein (s) in complex with broadly neutralizing antibody pw5-535 (Complex from Homo sapiens)
- Pw5-535 heavy chain (49 kDa, Protein from Homo sapiens)
- Spike glycoprotein (131 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
The local refined map of SARS-CoV Spike protein complexed with antibody PW5-5
Zhao X, Qiu T, Huang X, Mao Q, Wang Y, Qiao R, Li J, Mao T, Wang Y, Cun Y, Wang C, Luo C, Yoon C, Wang X, Li C, Cui Y, Zhao C, Li M, Chen Y, Cai G, Geng W, Hu Z, Cao J, Zhang W, Cao Z, Chu H, Sun L, Wang P
Cell Discov (2024) 10 pp. 14-14 [ Pubmed: 38320990 DOI: doi:10.1038/s41421-024-00648-1 ]
- Spike glycoprotein (131 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Sars spike protein (s) in complex with broadly neutralizing antibody pw5-5 (Complex from Severe acute respiratory syndrome coronavirus 2)
- Pw5-5 heavy chain (49 kDa, Protein from Homo sapiens)
- Pw5-5 light chain (23 kDa, Protein from Homo sapiens)