To Be Published
- Triheteromeric nmda receptor glun1-glun2a-glun3a in complex with glycine, glutamate, a glun1-specific fab,and a glun2a-specific fab (Complex from Rattus norvegicus)
- Glun1-specific antibody fragment heavy chain (23 kDa, Protein from Mus musculus)
- Glun1-specific antibody fragment light chain (25 kDa, Protein from Mus musculus)
- Glutamate receptor ionotropic, nmda 2a,enhanced green fluorescent protein (125 kDa, Protein from Muromegalovirus G4)
- Glutamate receptor ionotropic, nmda 3a,enhanced green fluorescent protein (137 kDa, Protein from Muromegalovirus G4)
- Glutamate receptor ionotropic, nmda 1 (95 kDa, Protein from Rattus norvegicus)
- Glun2a-specific antibody fragment light chain (23 kDa, Protein from Mus musculus)
- Glun2a-specific antibody fragment heavy chain (24 kDa, Protein from Mus musculus)
Saunders KO, Counts J, Thakur B, Stalls V, Edwards R, Manne K, Lu X, Mansouri K, Chen Y, Parks R, Barr M, Sutherland L, Bal J, Havill N, Chen H, Machiele E, Jamieson N, Hora B, Kopp M, Janowska K, Anasti K, Jiang C, Van Itallie E, Venkatayogi S, Eaton A, Henderson R, Barbosa C, Alam SM, Santra S, Weissman D, Moody MA, Cain DW, Tam YK, Lewis M, Williams WB, Wiehe K, Montefiori DC, Acharya P, Haynes BF
Cell (2024) 187 pp. 79-94.e24 [ DOI: doi:10.1016/j.cell.2023.12.002 Pubmed: 38181743 ]
Cryo-EM structure of Antibody SKW11 in complex with Western Equine Encephalitis Virus-Like Particle
Sutton MS, Pletnev S, Callahan V, Ko S, Tsybovsky Y, Bylund T, Casner RG, Cerutti G, Gardner CL, Guirguis V, Verardi R, Zhang B, Ambrozak D, Beddall M, Lei H, Yang ES, Liu T, Henry AR, Rawi R, Schon A, Schramm CA, Shen CH, Shi W, Stephens T, Yang Y, Florez MB, Ledgerwood JE, Burke CW, Shapiro L, Fox JM, Kwong PD, Roederer M
Cell (2023) 186 pp. 2672-2689.e25 [ Pubmed: 37295404 DOI: doi:10.1016/j.cell.2023.05.019 ]
Cryo-EM I1 reconstruction of antibody SKV09 in complex with VEEV alphavirus VLP
Sutton MS, Pletnev S, Callahan V, Ko S, Tsybovsky Y, Bylund T, Casner RG, Cerutti G, Gardner CL, Guirguis V, Verardi R, Zhang B, Ambrozak D, Beddall M, Lei H, Yang ES, Liu T, Henry AR, Rawi R, Schon A, Schramm CA, Shen CH, Shi W, Stephens T, Yang Y, Florez MB, Ledgerwood JE, Burke CW, Shapiro L, Fox JM, Kwong PD, Roederer M
Cell (2023) 186 pp. 2672-2689.e25 [ Pubmed: 37295404 DOI: doi:10.1016/j.cell.2023.05.019 ]
To Be Published
- Vaccine elicited antibody dh1285 fab bound to ch505tfchim.6r.sosip.664.v4.1 trimer, 3-fab-bound configuration (353 kDa, Cellular component from Homo sapiens)
- Dh1285 fab light chain (Macromolecule from Macaca mulatta)
- Dh1285 fab heavy chain (Macromolecule from Macaca mulatta)
- Ch505tfchim.6r.sosip.664.v4.1 env trimer (Macromolecule from Human immunodeficiency virus 1)
Cryo-EM local refinement of antibody SKV09 in complex with VEEV alphavirus spike glycoprotein
Resolution: 6.0 Å
EM Method: Single-particle
Fitted PDBs: 8deq
Q-score: 0.19
Sutton MS, Pletnev S, Callahan V, Ko S, Tsybovsky Y, Bylund T, Casner RG, Cerutti G, Gardner CL, Guirguis V, Verardi R, Zhang B, Ambrozak D, Beddall M, Lei H, Yang ES, Liu T, Henry AR, Rawi R, Schon A, Schramm CA, Shen CH, Shi W, Stephens T, Yang Y, Florez MB, Ledgerwood JE, Burke CW, Shapiro L, Fox JM, Kwong PD, Roederer M
Cell (2023) 186 pp. 2672-2689.e25 [ Pubmed: 37295404 DOI: doi:10.1016/j.cell.2023.05.019 ]
- Cryo-em local refinement of antibody skv09 in complex with veev alphavirus spike glycoprotein (Complex from Venezuelan equine encephalitis virus)
- Skv09 fab heavy chain (13 kDa, Protein from Macaca)
- Spike glycoprotein e1 (43 kDa, Protein from Venezuelan equine encephalitis virus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Skv09 fab light chain (11 kDa, Protein from Macaca)
Cryo-EM structure of EBV glycoprotein complex gHgL-gp42 bound by a neutralizing antibody 6H2
Rabies virus glycoprotein trimer
Callaway HM, Zyla D, Larrous F, de Melo GD, Hastie KM, Avalos RD, Agarwal A, Corti D, Bourhy H, Saphire EO
Sci Adv (2022) 8 pp. eabp9151-eabp9151 [ DOI: doi:10.1126/sciadv.abp9151 Pubmed: 35714192 ]
Callaway HM, Zyla D, Larrous F, de Melo GD, Hastie KM, Avalos RD, Agarwal A, Corti D, Bourhy H, Saphire EO
Sci Adv (2022) 8 pp. eabp9151-eabp9151 [ DOI: doi:10.1126/sciadv.abp9151 Pubmed: 35714192 ]