To Be Published
- Triheteromeric nmda receptor glun1-glun2a-glun3a in complex with glycine, glutamate, a glun1-specific fab,and a glun2a-specific fab (Complex from Rattus norvegicus)
- Glun1-specific antibody fragment heavy chain (23 kDa, Protein from Mus musculus)
- Glun1-specific antibody fragment light chain (25 kDa, Protein from Mus musculus)
- Glutamate receptor ionotropic, nmda 2a,enhanced green fluorescent protein (125 kDa, Protein from Muromegalovirus G4)
- Glutamate receptor ionotropic, nmda 3a,enhanced green fluorescent protein (137 kDa, Protein from Muromegalovirus G4)
- Glutamate receptor ionotropic, nmda 1 (95 kDa, Protein from Rattus norvegicus)
- Glun2a-specific antibody fragment light chain (23 kDa, Protein from Mus musculus)
- Glun2a-specific antibody fragment heavy chain (24 kDa, Protein from Mus musculus)
Cryo-EM local refinement of antibody SKV09 in complex with VEEV alphavirus spike glycoprotein
Resolution: 6.0 Å
EM Method: Single-particle
Fitted PDBs: 8deq
Q-score: 0.19
Sutton MS, Pletnev S, Callahan V, Ko S, Tsybovsky Y, Bylund T, Casner RG, Cerutti G, Gardner CL, Guirguis V, Verardi R, Zhang B, Ambrozak D, Beddall M, Lei H, Yang ES, Liu T, Henry AR, Rawi R, Schon A, Schramm CA, Shen CH, Shi W, Stephens T, Yang Y, Florez MB, Ledgerwood JE, Burke CW, Shapiro L, Fox JM, Kwong PD, Roederer M
Cell (2023) 186 pp. 2672-2689.e25 [ Pubmed: 37295404 DOI: doi:10.1016/j.cell.2023.05.019 ]
- Cryo-em local refinement of antibody skv09 in complex with veev alphavirus spike glycoprotein (Complex from Venezuelan equine encephalitis virus)
- Skv09 fab heavy chain (13 kDa, Protein from Macaca)
- Spike glycoprotein e1 (43 kDa, Protein from Venezuelan equine encephalitis virus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Skv09 fab light chain (11 kDa, Protein from Macaca)
Rabies virus glycoprotein trimer
Callaway HM, Zyla D, Larrous F, de Melo GD, Hastie KM, Avalos RD, Agarwal A, Corti D, Bourhy H, Saphire EO
Sci Adv (2022) 8 pp. eabp9151-eabp9151 [ DOI: doi:10.1126/sciadv.abp9151 Pubmed: 35714192 ]
Callaway HM, Zyla D, Larrous F, de Melo GD, Hastie KM, Avalos RD, Agarwal A, Corti D, Bourhy H, Saphire EO
Sci Adv (2022) 8 pp. eabp9151-eabp9151 [ DOI: doi:10.1126/sciadv.abp9151 Pubmed: 35714192 ]
Antibody 10-28 in complex with prefusion SARS-CoV-2 B.1.351 Spike glycoprotein
Liu L, Iketani S, Guo Y, Reddem ER, Casner RG, Nair MS, Yu J, Chan JF, Wang M, Cerutti G, Li Z, Morano NC, Castagna CD, Corredor L, Chu H, Yuan S, Poon VK, Chan CC, Chen Z, Luo Y, Cunningham M, Chavez A, Yin MT, Perlin DS, Tsuji M, Yuen KY, Kwong PD, Sheng Z, Huang Y, Shapiro L, Ho DD
Sci Transl Med (2022) 14 pp. eabn6859-eabn6859 [ DOI: doi:10.1126/scitranslmed.abn6859 Pubmed: 35438546 ]
- Antibody 10-28 light (Protein from Homo sapiens)
- Antibody 10-28 heavy (Protein from Homo sapiens)
- Antibody 10-28 in complex with prefusion sars-cov-2 b.1.351 spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike glycoprotein (Protein from Severe acute respiratory syndrome coronavirus 2)
Antibody 11-11 in complex with prefusion SARS-CoV-2 B.1.351 Spike glycoprotein
Liu L, Iketani S, Guo Y, Reddem ER, Casner RG, Nair MS, Yu J, Chan JF, Wang M, Cerutti G, Li Z, Morano NC, Castagna CD, Corredor L, Chu H, Yuan S, Poon VK, Chan CC, Chen Z, Luo Y, Cunningham M, Chavez A, Yin MT, Perlin DS, Tsuji M, Yuen KY, Kwong PD, Sheng Z, Huang Y, Shapiro L, Ho DD
Sci Transl Med (2022) 14 pp. eabn6859-eabn6859 [ DOI: doi:10.1126/scitranslmed.abn6859 Pubmed: 35438546 ]
- Antibody 11-11 light chain (Protein from Homo sapiens)
- Antibody 11-11 heavy chain (Protein from Homo sapiens)
- Spike glycoprotein (Protein from Severe acute respiratory syndrome coronavirus 2)
- Antibody 11-11 in complex with prefusion sars-cov-2 b.1.351 spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
Full-length human E-cadherin bound to activating Fab 59D2
To Be Published
- Full length e-cadherin with twin-strep tag (80 kDa, Complex from Homo sapiens)
- Complex of human e-cadherin monomer with activating fab 59d2 (130 kDa, Complex)
- Activating antibody fragment 59d2 fab light chain (Protein from Mus musculus)
- Activating antibody fragment 59d2 fab heavy chain (Protein from Mus musculus)
- E-cadherin (cdh1) with c-terminal twin-strep tag (Protein from Homo sapiens)
- Activating antibody fragment 59d2 fab (50 kDa, Complex from Mus musculus)
Bundibugyo virus GP (mucin deleted) bound to antibody Fab BDBV-329 and EBOV-515
Resolution: 6.6 Å
EM Method: Single-particle
Fitted PDBs: 7kfe
Q-score: 0.171
Murin CD, Gilchuk P, Ilinykh PA, Huang K, Kuzmina N, Shen X, Bruhn JF, Bryan AL, Davidson E, Doranz BJ, Williamson LE, Copps J, Alkutkar T, Flyak AI, Bukreyev A, Crowe Jr JE, Ward AB
Cell Rep (2021) 35 pp. 108984-108984 [ Pubmed: 33852862 DOI: doi:10.1016/j.celrep.2021.108984 ]
- Envelope glycoprotein 2 (19 kDa, Protein from Bundibugyo ebolavirus)
- Antibody bdbv-329 light chain (23 kDa, Protein from Homo sapiens)
- Spike glycoprotein 1 (38 kDa, Protein from Bundibugyo ebolavirus)
- Antibody fab bdbv-329 (Complex from Homo sapiens)
- Antibody bdbv-329 heavy chain (25 kDa, Protein from Homo sapiens)
- Bundibugyo virus gp (mucin deleted) (Complex from Bundibugyo ebolavirus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Bundibugyo virus gp (mucin deleted) bound to antibody fab ebov-329 and ebov-515 (Complex from Bundibugyo ebolavirus)
Rujas E, Kucharska I, Tan YZ, Benlekbir S, Cui H, Zhao T, Wasney GA, Budylowski P, Guvenc F, Newton JC, Sicard T, Semesi A, Muthuraman K, Nouanesengsy A, Aschner CB, Prieto K, Bueler SA, Youssef S, Liao-Chan S, Glanville J, Christie-Holmes N, Mubareka S, Gray-Owen SD, Rubinstein JL, Treanor B, Julien JP
Nat Commun (2021) 12 pp. 3661-3661 [ DOI: doi:10.1038/s41467-021-23825-2 Pubmed: 34135340 ]
- Fab 80 light chain (Protein from Homo sapiens)
- Fab fragment of neutralizing antibody 80 (Complex from Homo sapiens)
- Sars-cov-2 spike in complex with the fab fragment of neutralizing antibody 80 (Complex)
- Sars-cov-2 spike (Complex from Severe acute respiratory syndrome coronavirus 2)
- Fab 80 heavy chain (Protein from Homo sapiens)
- Sars-cov-2 spike (Protein from Severe acute respiratory syndrome coronavirus 2)
Rujas E, Kucharska I, Tan YZ, Benlekbir S, Cui H, Zhao T, Wasney GA, Budylowski P, Guvenc F, Newton JC, Sicard T, Semesi A, Muthuraman K, Nouanesengsy A, Aschner CB, Prieto K, Bueler SA, Youssef S, Liao-Chan S, Glanville J, Christie-Holmes N, Mubareka S, Gray-Owen SD, Rubinstein JL, Treanor B, Julien JP
Nat Commun (2021) 12 pp. 3661-3661 [ DOI: doi:10.1038/s41467-021-23825-2 Pubmed: 34135340 ]
- Fab fragment of neutralizing antibody 298 (Complex from Homo sapiens)
- Sars-cov-2 spike in complex with the fab fragment of neutralizing antibody 298 (Complex)
- Fab 298 heavy chain (Protein from Homo sapiens)
- Fab 298 light chain (Protein from Homo sapiens)
- Sars-cov-2 spike (Complex from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2 spike (Protein from Severe acute respiratory syndrome coronavirus 2)