Structure of CXCR3 in the apo-state (Full map)
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 8xxz
Q-score: 0.464
Sano FK, Saha S, Sharma S, Ganguly M, Shihoya W, Nureki O, Shukla AK, Banerjee R
To Be Published
- Antibody fragment scfv16 (26 kDa, Protein from Mus musculus)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (38 kDa, Protein from Homo sapiens)
- Apo-cxcr3-go complex (Complex from Homo sapiens)
- C-x-c chemokine receptor type 3 (46 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(o) subunit alpha (27 kDa, Protein from Homo sapiens)
Structure of CXCR3 in complex with VUF10661 and Go (Full map)
Resolution: 3.03 Å
EM Method: Single-particle
Fitted PDBs: 8xyk
Q-score: 0.509
Sano FK, Saha S, Sharma S, Ganguly M, Shihoya W, Nureki O, Shukla AK, Banerjee R
To Be Published
- Antibody fragment scfv16 (26 kDa, Protein from Mus musculus)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- (3~{s})-~{n}-[(2~{s})-6-azanyl-1-(2,2-diphenylethylamino)-1-oxidanylidene-hexan-2-yl]-2-(4-oxidanylidene-4-phenyl-butanoyl)-3,4-dihydro-1~{h}-isoquinoline-3-carboxamide (644 Da, Ligand)
- Cxcr3 in complex with vuf10661 and go (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (38 kDa, Protein from Homo sapiens)
- C-x-c chemokine receptor type 3 (46 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(o) subunit alpha (27 kDa, Protein from Homo sapiens)
Structure of CXCR3 in complex with VUF11418 and Go (Full map)
Resolution: 3.07 Å
EM Method: Single-particle
Fitted PDBs: 8y0n
Q-score: 0.491
Sano FK, Saha S, Sharma S, Ganguly M, Shihoya W, Nureki O, Shukla AK, Banerjee R
To Be Published
- [(1~{r},5~{s})-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]methyl-[[4-(2-iodanylphenyl)phenyl]methyl]-dimethyl-azanium (472 Da, Ligand)
- Antibody fragment scfv16 (26 kDa, Protein from Mus musculus)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Cxcr3 in complex with vuf11418 and go (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (38 kDa, Protein from Homo sapiens)
- C-x-c chemokine receptor type 3 (46 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(o) subunit alpha (27 kDa, Protein from Homo sapiens)
HPV18 L1 pentamer in complex with Fab F5-203
Resolution: 2.93 Å
EM Method: Single-particle
Fitted PDBs: 8yei
Q-score: -0.02
To Be Published
- Major capsid protein l1 (50 kDa, Protein from human papillomavirus 18)
- Hpv18 l1 pentamer in complex with fab f5-203 (Complex)
- Heavy chain of antibody f5-203 (13 kDa, Protein from Homo sapiens)
- Light chain of antibody f5-203 (11 kDa, Protein from Homo sapiens)
- Hpv18 l1 pentamer (Complex from human papillomavirus 18)
- Fab f5-203 (Complex from Homo sapiens)
Cryo-EM structure of Medium-wave-sensitive opsin 1
Resolution: 2.48 Å
EM Method: Single-particle
Fitted PDBs: 8y01
Q-score: 0.54
Peng Q, Jiang HH, Cheng XY, Li J, Zhang J
To Be Published
- Retinal (284 Da, Ligand)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- M-opsin-gi (180 MDa, Complex from Homo)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Bos taurus)
- Medium-wave-sensitive opsin 1 (40 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Scfv recombinant human monoclonal antibody (scfv16) (28 kDa, Protein from Homo sapiens)
Cryo-EM structure of simian rotavirus SA11 VP4 in complex with nAb 7H13
Resolution: 3.47 Å
EM Method: Single-particle
Fitted PDBs: 8ygs
Q-score: 0.444
Huang Y, Song F, Zeng Y, Sun H, Sheng R, Wang X, Liu L, Luo G, Jiang Y, Chen Y, Zhang M, Zhang S, Gu Y, Yu H, Li S, Li T, Zheng Q, Ge S, Zhang J, Xia N
Nat Commun (2025) 16 pp. 838-838 [ Pubmed: 39833145 DOI: doi:10.1038/s41467-025-56114-3 ]
- Rotavirus vp4 (Complex from Rotavirus A)
- Immune complex of rotavirus with 7h13 (Complex from Rotavirus A)
- Fab 7h13 (Complex from Mus musculus)
- Antibody 7h13 heavy chain (12 kDa, Protein from Mus musculus)
- Outer capsid protein vp4 (64 kDa, Protein from Rotavirus A)
- Antibody 7h13 light chain (11 kDa, Protein from Mus musculus)
- Outer capsid protein vp4 (64 kDa, Protein from Rotavirus A)
Cryo-EM structure of simian rotavirus SA11 VP4 in complex with nAb 7H13-I54G mutant (left side)
Resolution: 3.01 Å
EM Method: Single-particle
Fitted PDBs: 8ygt
Q-score: 0.559
Huang Y, Song F, Zeng Y, Sun H, Sheng R, Wang X, Liu L, Luo G, Jiang Y, Chen Y, Zhang M, Zhang S, Gu Y, Yu H, Li S, Li T, Zheng Q, Ge S, Zhang J, Xia N
Nat Commun (2025) 16 pp. 838-838 [ Pubmed: 39833145 DOI: doi:10.1038/s41467-025-56114-3 ]
- Rotavirus vp4 (Complex from Rotavirus A)
- Immune complex of rotavirus with 7h13 (Complex from Rotavirus A)
- Fab 7h13 (Complex from Mus musculus)
- Antibody 7h13-i54g mutant heavy chain (12 kDa, Protein from Mus musculus)
- Antibody 7h13-i54g mutant light chain (11 kDa, Protein from Mus musculus)
- Outer capsid protein vp4 (64 kDa, Protein from Rotavirus A)
Cryo-EM structure of simian rotavirus SA11 VP4 in complex with nAb 7H13-I54G mutant (right side)
Resolution: 3.13 Å
EM Method: Single-particle
Fitted PDBs: 8ygu
Q-score: 0.526
Huang Y, Song F, Zeng Y, Sun H, Sheng R, Wang X, Liu L, Luo G, Jiang Y, Chen Y, Zhang M, Zhang S, Gu Y, Yu H, Li S, Li T, Zheng Q, Ge S, Zhang J, Xia N
Nat Commun (2025) 16 pp. 838-838 [ Pubmed: 39833145 DOI: doi:10.1038/s41467-025-56114-3 ]
- Rotavirus vp4 (Complex from Rotavirus A)
- Outer capsid protein vp4 (87 kDa, Protein from Rotavirus A)
- Immune complex of rotavirus with 7h13-i54g mutant (Complex from Rotavirus A)
- Fab 7h13 (Complex from Rotavirus A)
- Outer capsid protein vp4 (64 kDa, Protein from Rotavirus A)
- Antibody 7h13-i54g mutant light chain (11 kDa, Protein from Mus musculus)
- Antibody 7h13-i54g mutant heavy chain (12 kDa, Protein from Mus musculus)
Structure of XBB.1.16 S trimer with 2 down-RBDs complex with antibody CYFN1006-1.
Resolution: 2.84 Å
EM Method: Single-particle
Fitted PDBs: 8z6s
Q-score: 0.379
To Be Published
- Structure of xbb.1.16 s trimer with 2 down-rbds complex with antibody cyfn1006-1. (Complex from Severe acute respiratory syndrome coronavirus 2)
- Cyfn1006-1 heavy chain (49 kDa, Protein from Homo sapiens)
- Cyfn1006-1 light chain (22 kDa, Protein from Homo sapiens)
- Spike glycoprotein,fibritin,expression tag (143 kDa, Protein from synthetic construct)
Structure of EG.5.1 S trimer with 3 down-RBDs complex with antibody CYFN1006-2.
Resolution: 3.04 Å
EM Method: Single-particle
Fitted PDBs: 8z6w
Q-score: 0.351
To Be Published
- Spike glycoprotein,fibritin,expression tag (143 kDa, Protein from synthetic construct)
- Cyfn1006-2 heavy chain (23 kDa, Protein from Homo sapiens)
- Cyfn1006-2 light chain (22 kDa, Protein from Homo sapiens)
- Structure of eg.5.1 s trimer with 3 down-rbds complex with antibody cyfn1006-2. (Complex from Severe acute respiratory syndrome coronavirus 2)