To Be Published
- Triheteromeric nmda receptor glun1-glun2a-glun3a in complex with glycine, glutamate, a glun1-specific fab,and a glun2a-specific fab (Complex from Rattus norvegicus)
- Glun1-specific antibody fragment heavy chain (23 kDa, Protein from Mus musculus)
- Glun1-specific antibody fragment light chain (25 kDa, Protein from Mus musculus)
- Glutamate receptor ionotropic, nmda 2a,enhanced green fluorescent protein (125 kDa, Protein from Muromegalovirus G4)
- Glutamate receptor ionotropic, nmda 3a,enhanced green fluorescent protein (137 kDa, Protein from Muromegalovirus G4)
- Glutamate receptor ionotropic, nmda 1 (95 kDa, Protein from Rattus norvegicus)
- Glun2a-specific antibody fragment light chain (23 kDa, Protein from Mus musculus)
- Glun2a-specific antibody fragment heavy chain (24 kDa, Protein from Mus musculus)
Cryo-EM local refinement of antibody SKV09 in complex with VEEV alphavirus spike glycoprotein
Resolution: 6.0 Å
EM Method: Single-particle
Fitted PDBs: 8deq
Q-score: 0.19
Sutton MS, Pletnev S, Callahan V, Ko S, Tsybovsky Y, Bylund T, Casner RG, Cerutti G, Gardner CL, Guirguis V, Verardi R, Zhang B, Ambrozak D, Beddall M, Lei H, Yang ES, Liu T, Henry AR, Rawi R, Schon A, Schramm CA, Shen CH, Shi W, Stephens T, Yang Y, Florez MB, Ledgerwood JE, Burke CW, Shapiro L, Fox JM, Kwong PD, Roederer M
Cell (2023) 186 pp. 2672-2689.e25 [ Pubmed: 37295404 DOI: doi:10.1016/j.cell.2023.05.019 ]
- Cryo-em local refinement of antibody skv09 in complex with veev alphavirus spike glycoprotein (Complex from Venezuelan equine encephalitis virus)
- Skv09 fab heavy chain (13 kDa, Protein from Macaca)
- Spike glycoprotein e1 (43 kDa, Protein from Venezuelan equine encephalitis virus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Skv09 fab light chain (11 kDa, Protein from Macaca)
Bundibugyo virus GP (mucin deleted) bound to antibody Fab BDBV-329 and EBOV-515
Resolution: 6.6 Å
EM Method: Single-particle
Fitted PDBs: 7kfe
Q-score: 0.171
Murin CD, Gilchuk P, Ilinykh PA, Huang K, Kuzmina N, Shen X, Bruhn JF, Bryan AL, Davidson E, Doranz BJ, Williamson LE, Copps J, Alkutkar T, Flyak AI, Bukreyev A, Crowe Jr JE, Ward AB
Cell Rep (2021) 35 pp. 108984-108984 [ Pubmed: 33852862 DOI: doi:10.1016/j.celrep.2021.108984 ]
- Envelope glycoprotein 2 (19 kDa, Protein from Bundibugyo ebolavirus)
- Antibody bdbv-329 light chain (23 kDa, Protein from Homo sapiens)
- Spike glycoprotein 1 (38 kDa, Protein from Bundibugyo ebolavirus)
- Antibody fab bdbv-329 (Complex from Homo sapiens)
- Antibody bdbv-329 heavy chain (25 kDa, Protein from Homo sapiens)
- Bundibugyo virus gp (mucin deleted) (Complex from Bundibugyo ebolavirus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Bundibugyo virus gp (mucin deleted) bound to antibody fab ebov-329 and ebov-515 (Complex from Bundibugyo ebolavirus)
Interphotoreceptor retinoid-binding protein (IRBP) in complex with a monoclonal antibody (F3F5 mAb5)
Resolution: 7.4 Å
EM Method: Single-particle
Fitted PDBs: 7jti
Q-score: 0.048
Sears AE, Albiez S, Gulati S, Wang B, Kiser P, Kovacik L, Engel A, Stahlberg H, Palczewski K
FASEB J (2020) 34 pp. 13918-13934 [ DOI: doi:10.1096/fj.202000796RR Pubmed: 32860273 ]
- Complex between interphotoreceptor retinoid-binding protein and a monoclonal antibody (193 kDa, Complex)
- Retinol-binding protein 3 (32 kDa, Protein from Bos taurus)
- Retinol-binding protein 3 (33 kDa, Protein from Bos taurus)
- Mab5 fab heavy chain (23 kDa, Protein from Mus musculus)
- Retinol-binding protein 3 (33 kDa, Protein from Bos taurus)
- Monoclonal antibody f3f5 mab5 (Complex from Mus musculus)
- Interphotoreceptor retinoid-binding protein (irbp) (Complex from Bos taurus)
- Mab5 fab light chain (22 kDa, Protein from Mus musculus)
- Retinol-binding protein 3 (32 kDa, Protein from Bos taurus)
Structure of full-length, fully glycosylated, non-modified HIV-1 gp160 bound to PG16 Fab
Resolution: 6.2 Å
EM Method: Single-particle
Fitted PDBs: 6pwu
Q-score: 0.151
Pan J, Peng H, Chen B, Harrison SC
J Mol Biol (2020) 432 pp. 1158-1168 [ DOI: doi:10.1016/j.jmb.2019.11.028 Pubmed: 31931014 ]
- Antibody pg16 fab light chain (26 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Hiv-1 gp160 trimer:pg16 fab complex (530 kDa, Complex)
- Antibody pg16 fab (Complex from Homo sapiens)
- Antibody pg16 fab heavy chain (31 kDa, Protein from Homo sapiens)
- Hiv-1 envelope glycoprotein gp160 (mature) (Complex from Human immunodeficiency virus 1)
- Envelope glycoprotein gp160 (97 kDa, Protein from Human immunodeficiency virus 1)
Fit R10 Fab coordinates into the cryo-EM of EV71 in complex with A9
Resolution: 6.8 Å
EM Method: Single-particle
Fitted PDBs: 5zuf
Q-score: 0.127
Zhu L, Xu K, Wang N, Cao L, Wu J, Gao Q, Fry EE, Stuart DI, Rao Z, Wang J, Wang X
Mbio (2018) 9 [ DOI: doi:10.1128/mBio.01013-18 Pubmed: 29970466 ]
- Capsid protein vp1 (32 kDa, Protein from Enterovirus A71)
- Vp2 (26 kDa, Protein from Enterovirus A71)
- R10 antibody heavy chain (23 kDa, Protein from Mus musculoides)
- A9 neutralizing antibody fab (Complex from Mus musculoides)
- Vp3 (26 kDa, Protein from Enterovirus A71)
- R10 antibody light chain (23 kDa, Protein from Mus musculoides)
- Complex of ev71 and a9 neutralizing antibody fab (Complex)
- Ev71 (Complex from Enterovirus A71)
CryoEM structure of chimeric Eastern Equine Encephalitis Virus with Fab of EEEV-42 antibody
Resolution: 7.7 Å
EM Method: Single-particle
Fitted PDBs: 6mui
Q-score: 0.075
Hasan SS, Sun C, Kim AS, Watanabe Y, Chen CL, Klose T, Buda G, Crispin M, Diamond MS, Klimstra WB, Rossmann MG
Cell Rep (2018) 25 pp. 3136-3147.e5 [ Pubmed: 30540945 DOI: doi:10.1016/j.celrep.2018.11.067 ]
- E2 (53 kDa, Protein from Eastern equine encephalitis virus)
- Eeev-42 fab (Complex from Mus musculus)
- Eeev-42 antibody heavy chain (23 kDa, Protein from Mus musculus)
- Eastern equine encephalitis virus (Virus from Eastern equine encephalitis virus)
- E1 (47 kDa, Protein from Eastern equine encephalitis virus)
- Eeev-42 antibody light chain (23 kDa, Protein from Mus musculus)
- Eastern equine encephalitis virus / eeev-42 fab complex (Complex)
CryoEM structure of chimeric Eastern Equine Encephalitis Virus with Fab of EEEV-3 antibody
Resolution: 7.3 Å
EM Method: Single-particle
Fitted PDBs: 6mw9
Q-score: 0.097
Hasan SS, Sun C, Kim AS, Watanabe Y, Chen CL, Klose T, Buda G, Crispin M, Diamond MS, Klimstra WB, Rossmann MG
Cell Rep (2018) 25 pp. 3136-3147.e5 [ Pubmed: 30540945 DOI: doi:10.1016/j.celrep.2018.11.067 ]
- Eeev-3 antibody light chain (23 kDa, Protein from Mus musculus)
- Eeev-3 antibody heavy chain (23 kDa, Protein from Mus musculus)
- Eastern equine encephalitis virus / eeev-3 fab complex (Complex)
- Eastern equine encephalitis virus (Complex from Eastern equine encephalitis virus)
- E1 (47 kDa, Protein from Eastern equine encephalitis virus)
- Eeev-3 fab (Complex from Mus musculus)
- E2 (47 kDa, Protein from Eastern equine encephalitis virus)
CryoEM structure of chimeric Eastern Equine Encephalitis Virus with Fab of EEEV-5 antibody
Resolution: 7.5 Å
EM Method: Single-particle
Fitted PDBs: 6mwc
Q-score: 0.087
Hasan SS, Sun C, Kim AS, Watanabe Y, Chen CL, Klose T, Buda G, Crispin M, Diamond MS, Klimstra WB, Rossmann MG
Cell Rep (2018) 25 pp. 3136-3147.e5 [ Pubmed: 30540945 DOI: doi:10.1016/j.celrep.2018.11.067 ]
- Eastern equine encephalitis virus / eeev-5 fab complex (Complex)
- Eeev-5 fab (Complex from Mus musculus)
- Eeev-5 antibody heavy chain (23 kDa, Protein from Mus musculus)
- Eastern equine encephalitis virus (Complex from Eastern equine encephalitis virus)
- E1 (47 kDa, Protein from Eastern equine encephalitis virus)
- E2 (47 kDa, Protein from Eastern equine encephalitis virus)
- Eeev-5 antibody light chain (23 kDa, Protein from Mus musculus)
CryoEM structure of Chimeric Eastern Equine Encephalitis Virus with Fab of EEEV-58 Antibody
Resolution: 7.3 Å
EM Method: Single-particle
Fitted PDBs: 6mwv
Q-score: 0.092
Hasan SS, Sun C, Kim AS, Watanabe Y, Chen CL, Klose T, Buda G, Crispin M, Diamond MS, Klimstra WB, Rossmann MG
Cell Rep (2018) 25 pp. 3136-3147.e5 [ Pubmed: 30540945 DOI: doi:10.1016/j.celrep.2018.11.067 ]
- Eeev-58 antibody light chain (23 kDa, Protein from Mus musculus)
- Eeev-58 antibody heavy chain (23 kDa, Protein from Mus musculus)
- E1 (47 kDa, Protein from Eastern equine encephalitis virus)
- Eastern equine encephalitis virus (Complex from Eastern equine encephalitis virus)
- Eastern equine encephalitis virus / eeev-58 fab complex (Complex)
- Eeev-58 fab (Complex from Mus musculus)
- E2 (47 kDa, Protein from Eastern equine encephalitis virus)