Cryo-EM structure of Medium-wave-sensitive opsin 1
Resolution: 2.48 Å
EM Method: Single-particle
Fitted PDBs: 8y01
Q-score: 0.54
Peng Q, Jiang HH, Cheng XY, Li J, Zhang J
To Be Published
- Retinal (284 Da, Ligand)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- M-opsin-gi (180 MDa, Complex from Homo)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Bos taurus)
- Medium-wave-sensitive opsin 1 (40 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Scfv recombinant human monoclonal antibody (scfv16) (28 kDa, Protein from Homo sapiens)
Resolution: 3.06 Å
EM Method: Single-particle
Fitted PDBs: 8znz
Q-score: 0.547
Xu JG, Chen S, He Y, Zhu X, Wang Y, Ye Z, Zhou JC, Wu X, Zhang L, Ren X, Jia H, Yu H, Wei X, Feng Y, Chen X, Cui X, Pan X, Wang S, Xia S, Shang H, Pu Y, Xu W, Li H, Chen Q, Chen Z, Wang M, Yan X, Shi H, Li M, Xia Y, Bellelli R, Dong S, He J, Huang J, Cai CL, Zhu X, Zhan Y, Wan L
Nat Commun (2024) 15 pp. 10872-10872 [ DOI: doi:10.1038/s41467-024-55207-9 Pubmed: 39738003 ]
- Hb0039 fab heavy chain (13 kDa, Protein from Homo sapiens)
- Hb0038 fab light chain (11 kDa, Protein from Homo sapiens)
- Hb0039 fab light chain (11 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Sodium ion (22 Da, Ligand)
- 5'-nucleotidase (58 kDa, Protein from Homo sapiens)
- Cd73 complexed with hb0017 antibody coaktail (630 kDa, Complex from Homo sapiens)
- Calcium ion (40 Da, Ligand)
- Hb0038 fab heavy chain (13 kDa, Protein from Homo sapiens)
Fibriansah G, Ng TS, Lim XN, Tan AWK, Shi J, Crowe JE, Lok SM
To Be Published
- Human antibody 2d22 fab heavy chain (13 kDa, Protein from Homo sapiens)
- Envelope protein (54 kDa, Protein from dengue virus type 2)
- Dengue serotype 2 strain d2y98p-pp1 n153q mutant (Complex from dengue virus type 2)
- Dengue virus serotype 2 strain y98p-pp1 n153q mutant in complex with human antibody 2d22 fab at 37 deg c (Complex)
- Human antibody 2d22 fab light chain (12 kDa, Protein from Homo sapiens)
- Human antibody 2d22 fab (heavy and light chains) (Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Membrane polyprotein (8 kDa, Protein from dengue virus type 2)
Fibriansah G, Ng TS, Lim XN, Tan AWK, Shi J, Crowe JE, Lok SM
To Be Published
- Human antibody c10 fab (heavy chain) (14 kDa, Protein from Homo sapiens)
- Dengue virus serotype 2 strain y98p-pp1 n153q mutant in complex with human antibody c10 fab at 37 deg c (Complex)
- Envelope protein (54 kDa, Protein from dengue virus type 2)
- Human antibody c10 fab (light chain) (11 kDa, Protein from Homo sapiens)
- Dengue serotype 2 strain d2y98p-pp1 n153q mutant (Complex from dengue virus type 2)
- Membrane protein (8 kDa, Protein from dengue virus type 2)
- Human antibody c10 fab (heavy and light chains) (Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Fibriansah G, Ng TS, Lim XN, Tan AWK, Shi J, Crowe JE, Lok SM
To Be Published
- Dengue serotype 2 strain d2y98p-pp1 (Complex from dengue virus type 2)
- Envelope protein (54 kDa, Protein from dengue virus type 2)
- Dengue virus serotype 2 strain d2y98p-pp1 in complex with human antibody 2d22 fab at 37 deg c (Complex)
- Human antibody 2d22 fab (light chain) (12 kDa, Protein from Homo sapiens)
- Human antibody 2d22 fab (heavy chain) (13 kDa, Protein from Homo sapiens)
- Human antibody 2d22 fab (heavy and light chains) (Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Membrane polyprotein (8 kDa, Protein from dengue virus type 2)
Fibriansah G, Ng TS, Lim XN, Tan AWK, Shi J, Crowe JE, Lok SM
To Be Published
- Dengue virus type 2 (Virus)
- Dengue serotype 2 strain d2y98p-pp1 (Complex from dengue virus type 2)
- Human antibody c10 fab (heavy chain) (14 kDa, Protein from Homo sapiens)
- Envelope protein (54 kDa, Protein from dengue virus type 2)
- Human antibody c10 fab (light chain) (11 kDa, Protein from Homo sapiens)
- Human antibody c10 fab (heavy and light chains) (Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Membrane polyprotein (8 kDa, Protein from dengue virus type 2)
HIV 16055.v8.3 SOSIP Env in Complex with V2 Epitope and Anti-Immune Complex pAbs from Rabbit 2464
Brown S, Antanasijevic A, Sewall LM, Garcia DM, Brouwer PJM, Sanders RW, Ward AB
Sci Immunol (2025) 10 pp. eadp5218-eadp5218 [ Pubmed: 39823319 DOI: doi:10.1126/sciimmunol.adp5218 ]
- Rabbit anti-immune complex antibody - predicted light chain (9 kDa, Protein from Oryctolagus cuniculus)
- Rabbit v2 polyclonal antibody - predicted light chain (9 kDa, Protein from Oryctolagus cuniculus)
- Rabbit v2 polyclonal antibody - predicted heavy chain (10 kDa, Protein from Oryctolagus cuniculus)
- Transmembrane protein gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- Surface protein gp120 (58 kDa, Protein from Human immunodeficiency virus 1)
- Hiv-1 16055 sosip env in complex with rabbit polyclonal antibodies - v2 epitope and anti-immune complex pabs (Complex from Oryctolagus cuniculus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Rabbit anti-immune complex antibody - predicted heavy chain (9 kDa, Protein from Oryctolagus cuniculus)
HIV BG505.v5.2 (N289/N241) SOSIP Env in Complex with gp120-Interface pAb from Rh.33203
Brown S, Antanasijevic A, Sewall LM, Garcia DM, Brouwer PJM, Sanders RW, Ward AB
Sci Immunol (2025) 10 pp. eadp5218-eadp5218 [ Pubmed: 39823319 DOI: doi:10.1126/sciimmunol.adp5218 ]
- Hiv-1 bg505 sosip env in complex with nhp polyclonal antibody - gp120-interface epitope (Complex from Macaca mulatta)
- Gp120-interface polyclonal antibody - predicted light chain (8 kDa, Protein from Macaca mulatta)
- Gp120-interface polyclonal antibody - predicted heavy chain (9 kDa, Protein from Macaca mulatta)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Transmembrane protein gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- Surface protein gp120 (57 kDa, Protein from Human immunodeficiency virus 1)
HIV 16055.v8.3 SOSIP Env in Complex with Base and N625 Epitope pAbs from Rabbit 2463
Brown S, Antanasijevic A, Sewall LM, Garcia DM, Brouwer PJM, Sanders RW, Ward AB
Sci Immunol (2025) 10 pp. eadp5218-eadp5218 [ Pubmed: 39823319 DOI: doi:10.1126/sciimmunol.adp5218 ]
- Rabbit polyclonal antibody n625 epitope - predicted heavy chain (10 kDa, Protein from Oryctolagus cuniculus)
- Alpha-d-mannopyranose (180 Da, Ligand)
- Transmembrane protein gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- Rabbit polyclonal antibody base epitope - predicted light chain (9 kDa, Protein from Oryctolagus cuniculus)
- Surface protein gp120 (58 kDa, Protein from Human immunodeficiency virus 1)
- Rabbit polyclonal antibody base epitope - predicted heavy chain (10 kDa, Protein from Oryctolagus cuniculus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Rabbit polyclonal antibody n625 epitope - predicted light chain (9 kDa, Protein from Oryctolagus cuniculus)
- Hiv 16055 sosip env in complex with base and n625 epitope polyclonal antibodies (Complex from Oryctolagus cuniculus)
HIV 16055.v8.3 SOSIP Env in Complex with Base and N611 Epitope pAbs from Rabbit 2463
Brown S, Antanasijevic A, Sewall LM, Garcia DM, Brouwer PJM, Sanders RW, Ward AB
Sci Immunol (2025) 10 pp. eadp5218-eadp5218 [ Pubmed: 39823319 DOI: doi:10.1126/sciimmunol.adp5218 ]
- Rabbit n611 epitope polyclonal antibody - predicted light chain (8 kDa, Protein from Oryctolagus cuniculus)
- Rabbit n611 epitope polyclonal antibody - predicted heavy chain (9 kDa, Protein from Oryctolagus cuniculus)
- Rabbit base epitope polyclonal antibody - predicted light chain (9 kDa, Protein from Oryctolagus cuniculus)
- Rabbit base epitope polyclonal antibody - predicted heavy chain (10 kDa, Protein from Oryctolagus cuniculus)
- Transmembrane protein gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- Hiv-1 16055 sosip env in complex with rabbit polyclonal antibodies - base and n611 pabs (Complex from Oryctolagus cuniculus)
- Surface protein gp120 (58 kDa, Protein from Human immunodeficiency virus 1)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)