DH270.6 Fab bound to the HIV-1 CH848 DE3 SOSIP
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 8vgv
Q-score: 0.453
Henderson R, Anasti K, Manne K, Stalls V, Saunders C, Bililign Y, Williams A, Bubphamala P, Montani M, Kachhap S, Li J, Jaing C, Newman A, Cain DW, Lu X, Venkatayogi S, Berry M, Wagh K, Korber B, Saunders KO, Tian M, Alt F, Wiehe K, Acharya P, Alam SM, Haynes BF
Nat Commun (2024) 15 pp. 9503-9503 [ Pubmed: 39489734 DOI: doi:10.1038/s41467-024-53120-9 ]
- Ch848 de3 sosip gp120 (51 kDa, Protein from Human immunodeficiency virus 1)
- Ch848 de3 sosip gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- Dh270.6 antibody fab light chain (11 kDa, Protein from Homo sapiens)
- Antibody fab bound hiv-1 ectodomain (Complex from Human immunodeficiency virus 1)
- Dh270.6 antibody fab heavy chain (14 kDa, Protein from Homo sapiens)
SARS-CoV-2 spike glycoprotein in complex with the ICO-hu23 neutralizing antibody Fab fragment
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 8elj
Q-score: 0.343
Hermet P, Delache B, Herate C, Wolf E, Kivi G, Juronen E, Mumm K, Zusinaite E, Kainov D, Sankovski E, Virumae K, Planken A, Merits A, Besaw JE, Yee AW, Morizumi T, Kim K, Kuo A, Berriche A, Dereuddre-Bosquet N, Sconosciuti Q, Naninck T, Relouzat F, Cavarelli M, Ustav M, Wilson D, Ernst OP, Mannik A, LeGrand R, Ustav Jr M
PLoS Pathog (2023) 19 pp. e1011532-e1011532 [ DOI: doi:10.1371/journal.ppat.1011532 Pubmed: 37531329 ]
- Sars-cov-2 spike glycoprotein (Cellular component from Severe acute respiratory syndrome coronavirus 2)
- Ico-hu23 antibody fab light chain (22 kDa, Protein from Homo sapiens)
- Ico-hu23 antibody fab heavy chain (25 kDa, Protein from Homo sapiens)
- Ico-hu23 antibody fab fragment (Cellular component from Homo sapiens)
- Sars-cov-2 spike glycoprotein in complex with the ico-hu23 antibody fab fragment (Complex)
- Spike glycoprotein (139 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Luo S, Zhang J, Kreutzberger AJB, Eaton A, Edwards RJ, Jing C, Dai HQ, Sempowski GD, Cronin K, Parks R, Ye AY, Mansouri K, Barr M, Pishesha N, Williams AC, Vieira Francisco L, Saminathan A, Peng H, Batra H, Bellusci L, Khurana S, Alam SM, Montefiori DC, Saunders KO, Tian M, Ploegh H, Kirchhausen T, Chen B, Haynes BF, Alt FW
Sci Immunol (2022) 7 pp. eadd5446-eadd5446 [ DOI: doi:10.1126/sciimmunol.add5446 Pubmed: 35951767 ]
- Sp1-77 antibody fab light chain, sp1-77 antibody fab heavy chain (Complex from Mus musculus)
- Sars-cov2 2p spike (Protein from Severe acute respiratory syndrome coronavirus)
- Sars-cov2 2p spike (Complex from Severe acute respiratory syndrome coronavirus)
- Complex of sars-cov2 2p spike with sp1-77 antibody fab (48 kDa, Complex)
- Sp1-77 antibody fab light chain (Protein from Mus musculus)
- Sp1-77 antibody fab heavy chain (Protein from Mus musculus)
Luo S, Zhang J, Kreutzberger AJB, Eaton A, Edwards RJ, Jing C, Dai HQ, Sempowski GD, Cronin K, Parks R, Ye AY, Mansouri K, Barr M, Pishesha N, Williams AC, Vieira Francisco L, Saminathan A, Peng H, Batra H, Bellusci L, Khurana S, Alam SM, Montefiori DC, Saunders KO, Tian M, Ploegh H, Kirchhausen T, Chen B, Haynes BF, Alt FW
Sci Immunol (2022) 7 pp. eadd5446-eadd5446 [ DOI: doi:10.1126/sciimmunol.add5446 Pubmed: 35951767 ]
- Vhh7-7-53 antibody light chain (Protein from Mus musculus)
- Vhh7-7-53 antibody fab light chain, vhh7-7-53 antibody fab heavy chain (Complex from Mus musculus)
- Sars-cov2 2p spike (Protein from Severe acute respiratory syndrome coronavirus)
- Sars-cov2 2p spike (Complex from Severe acute respiratory syndrome coronavirus)
- Complex of sars-cov2 2p spike with vhh7-7-53 antibody fab (48 kDa, Complex)
- Vhh7-7-53 antibody heavy chain (Protein from Mus musculus)
Luo S, Zhang J, Kreutzberger AJB, Eaton A, Edwards RJ, Jing C, Dai HQ, Sempowski GD, Cronin K, Parks R, Ye AY, Mansouri K, Barr M, Pishesha N, Williams AC, Vieira Francisco L, Saminathan A, Peng H, Batra H, Bellusci L, Khurana S, Alam SM, Montefiori DC, Saunders KO, Tian M, Ploegh H, Kirchhausen T, Chen B, Haynes BF, Alt FW
Sci Immunol (2022) 7 pp. eadd5446-eadd5446 [ DOI: doi:10.1126/sciimmunol.add5446 Pubmed: 35951767 ]
- Sars-cov2 2p spike (Protein from Severe acute respiratory syndrome coronavirus)
- Vhh7-5-82 antibody fab light chain, vhh7-5-82 antibody fab heavy chain (Complex from Mus musculus)
- Sars-cov2 2p spike (Complex from Severe acute respiratory syndrome coronavirus)
- Complex of sars-cov2 2p spike with vhh7-5-82 antibody fab (48 kDa, Complex)
- Vhh7-5-82 antibody fab heavy chain (Protein from Mus musculus)
- Vhh7-5-82 antibody fab light chain (Protein from Mus musculus)
apo SERT reconstituted in lipid nanodisc in KCl
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7li6
Q-score: 0.436
Sci Adv (2021) 7 pp. eabl3857-eabl3857 [ Pubmed: 34851672 DOI: doi:10.1126/sciadv.abl3857 ]
- Hexadecane (226 Da, Ligand)
- Sodium-dependent serotonin transporter (60 kDa, Protein from Homo sapiens)
- Pentane (72 Da, Ligand)
- Dodecane (170 Da, Ligand)
- Variable domain of 15b8 antibody fab heavy chain (12 kDa, Protein from Mus musculus)
- Heptane (100 Da, Ligand)
- Chloride ion (35 Da, Ligand)
- Variable domain of 15b8 antibody fab light chain (11 kDa, Protein from Mus musculus)
- Decane (142 Da, Ligand)
- Apo state of human serotonin transporter in complex with 15b8 fab in kcl (Complex from Homo sapiens)
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 7li7
Q-score: 0.364
Sci Adv (2021) 7 pp. eabl3857-eabl3857 [ Pubmed: 34851672 DOI: doi:10.1126/sciadv.abl3857 ]
- Pentane (72 Da, Ligand)
- Dodecane (170 Da, Ligand)
- Variable domain of 15b8 antibody fab heavy chain (12 kDa, Protein from Mus musculus)
- Sodium-dependent serotonin transporter (60 kDa, Protein from Homo sapiens)
- Heptane (100 Da, Ligand)
- Variable domain of 15b8 antibody fab light chain (11 kDa, Protein from Mus musculus)
- Cholesterol (386 Da, Ligand)
- Decane (142 Da, Ligand)
- Apo human serotonin transporter in complex with 15b8 fab in nacl (Complex from Homo sapiens)
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 7li8
Q-score: 0.376
Sci Adv (2021) 7 pp. eabl3857-eabl3857 [ Pubmed: 34851672 DOI: doi:10.1126/sciadv.abl3857 ]
- Hexadecane (226 Da, Ligand)
- Sodium-dependent serotonin transporter (60 kDa, Protein from Homo sapiens)
- Pentane (72 Da, Ligand)
- Dodecane (170 Da, Ligand)
- Variable domain of 15b8 antibody fab heavy chain (12 kDa, Protein from Mus musculus)
- Heptane (100 Da, Ligand)
- Variable domain of 15b8 antibody fab light chain (11 kDa, Protein from Mus musculus)
- Decane (142 Da, Ligand)
- Apo human serotonin transporter in complex with 15b8 fab in nacl (Complex from Homo sapiens)
5-HT bound serotonin transporter reconstituted in lipid nanodisc in KCl
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 7li9
Q-score: 0.38
Sci Adv (2021) 7 pp. eabl3857-eabl3857 [ Pubmed: 34851672 DOI: doi:10.1126/sciadv.abl3857 ]
- Sodium-dependent serotonin transporter (60 kDa, Protein from Homo sapiens)
- Serotonin (176 Da, Ligand)
- Pentane (72 Da, Ligand)
- Dodecane (170 Da, Ligand)
- Variable domain of 15b8 antibody fab heavy chain (12 kDa, Protein from Mus musculus)
- Heptane (100 Da, Ligand)
- Chloride ion (35 Da, Ligand)
- Variable domain of 15b8 antibody fab light chain (11 kDa, Protein from Mus musculus)
- Decane (142 Da, Ligand)
- Human serotonin transporter in complex with 15b8 fab in kcl in presence of serotonin (Complex from Homo sapiens)
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 7lia
Q-score: 0.498
Sci Adv (2021) 7 pp. eabl3857-eabl3857 [ Pubmed: 34851672 DOI: doi:10.1126/sciadv.abl3857 ]
- Sodium-dependent serotonin transporter (60 kDa, Protein from Homo sapiens)
- Serotonin (176 Da, Ligand)
- Pentane (72 Da, Ligand)
- Human serotonin transporter in complex with 15b8 fab in presence of serotonin in nacl (Complex from Homo sapiens)
- Variable domain of 15b8 antibody fab heavy chain (12 kDa, Protein from Mus musculus)
- Heptane (100 Da, Ligand)
- Chloride ion (35 Da, Ligand)
- Variable domain of 15b8 antibody fab light chain (11 kDa, Protein from Mus musculus)
- Sodium ion (22 Da, Ligand)
- Decane (142 Da, Ligand)
- Cholesterol (386 Da, Ligand)