apo SERT reconstituted in lipid nanodisc in KCl
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7li6
Q-score: 0.436
Sci Adv (2021) 7 pp. eabl3857-eabl3857 [ Pubmed: 34851672 DOI: doi:10.1126/sciadv.abl3857 ]
- Hexadecane (226 Da, Ligand)
- Sodium-dependent serotonin transporter (60 kDa, Protein from Homo sapiens)
- Pentane (72 Da, Ligand)
- Dodecane (170 Da, Ligand)
- Variable domain of 15b8 antibody fab heavy chain (12 kDa, Protein from Mus musculus)
- Heptane (100 Da, Ligand)
- Chloride ion (35 Da, Ligand)
- Variable domain of 15b8 antibody fab light chain (11 kDa, Protein from Mus musculus)
- Decane (142 Da, Ligand)
- Apo state of human serotonin transporter in complex with 15b8 fab in kcl (Complex from Homo sapiens)
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 7li7
Q-score: 0.364
Sci Adv (2021) 7 pp. eabl3857-eabl3857 [ Pubmed: 34851672 DOI: doi:10.1126/sciadv.abl3857 ]
- Pentane (72 Da, Ligand)
- Dodecane (170 Da, Ligand)
- Variable domain of 15b8 antibody fab heavy chain (12 kDa, Protein from Mus musculus)
- Sodium-dependent serotonin transporter (60 kDa, Protein from Homo sapiens)
- Heptane (100 Da, Ligand)
- Variable domain of 15b8 antibody fab light chain (11 kDa, Protein from Mus musculus)
- Cholesterol (386 Da, Ligand)
- Decane (142 Da, Ligand)
- Apo human serotonin transporter in complex with 15b8 fab in nacl (Complex from Homo sapiens)
5-HT bound serotonin transporter reconstituted in lipid nanodisc in KCl
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 7li9
Q-score: 0.38
Sci Adv (2021) 7 pp. eabl3857-eabl3857 [ Pubmed: 34851672 DOI: doi:10.1126/sciadv.abl3857 ]
- Sodium-dependent serotonin transporter (60 kDa, Protein from Homo sapiens)
- Serotonin (176 Da, Ligand)
- Pentane (72 Da, Ligand)
- Dodecane (170 Da, Ligand)
- Variable domain of 15b8 antibody fab heavy chain (12 kDa, Protein from Mus musculus)
- Heptane (100 Da, Ligand)
- Chloride ion (35 Da, Ligand)
- Variable domain of 15b8 antibody fab light chain (11 kDa, Protein from Mus musculus)
- Decane (142 Da, Ligand)
- Human serotonin transporter in complex with 15b8 fab in kcl in presence of serotonin (Complex from Homo sapiens)
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 7lia
Q-score: 0.498
Sci Adv (2021) 7 pp. eabl3857-eabl3857 [ Pubmed: 34851672 DOI: doi:10.1126/sciadv.abl3857 ]
- Sodium-dependent serotonin transporter (60 kDa, Protein from Homo sapiens)
- Serotonin (176 Da, Ligand)
- Pentane (72 Da, Ligand)
- Human serotonin transporter in complex with 15b8 fab in presence of serotonin in nacl (Complex from Homo sapiens)
- Variable domain of 15b8 antibody fab heavy chain (12 kDa, Protein from Mus musculus)
- Heptane (100 Da, Ligand)
- Chloride ion (35 Da, Ligand)
- Variable domain of 15b8 antibody fab light chain (11 kDa, Protein from Mus musculus)
- Sodium ion (22 Da, Ligand)
- Decane (142 Da, Ligand)
- Cholesterol (386 Da, Ligand)
Structure of human 1G05 Fab in complex with influenza virus neuraminidase from B/Phuket/3073/2013
Resolution: 2.5 Å
EM Method: Single-particle
Fitted PDBs: 6v4n
Q-score: 0.594
Madsen A, Dai YN, McMahon M, Schmitz AJ, Turner JS, Tan J, Lei T, Alsoussi WB, Strohmeier S, Amor M, Mohammed BM, Mudd PA, Simon V, Cox RJ, Fremont DH, Krammer F, Ellebedy AH
Immunity (2020) 53 pp. 852- [ Pubmed: 32976769 DOI: doi:10.1016/j.immuni.2020.08.015 ]
- Water (18 Da, Ligand)
- Influenza virus neuraminidase (Complex from Influenza B virus)
- Structure of human 1g05 fab in complex with influenza virus neuraminidase from b/phuket/3073/2013 (400 kDa, Complex)
- Antibody fab light chain (23 kDa, Protein from Homo sapiens)
- Beta-d-mannopyranose (180 Da, Ligand)
- Neuraminidase (50 kDa, Protein from Influenza B virus)
- Calcium ion (40 Da, Ligand)
- Antibody fab heavy chain (26 kDa, Protein from Homo sapiens)
- Human antibody (Complex from Homo sapiens)
Structure of human 2E01 Fab in complex with influenza virus neuraminidase from B/Phuket/3073/2013
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 6v4o
Q-score: 0.525
Madsen A, Dai YN, McMahon M, Schmitz AJ, Turner JS, Tan J, Lei T, Alsoussi WB, Strohmeier S, Amor M, Mohammed BM, Mudd PA, Simon V, Cox RJ, Fremont DH, Krammer F, Ellebedy AH
Immunity (2020) 53 pp. 852- [ Pubmed: 32976769 DOI: doi:10.1016/j.immuni.2020.08.015 ]
- Antibody fab light chain (23 kDa, Protein from Homo sapiens)
- Influenza virus neuraminidase (Complex from Influenza B virus)
- Structure of human 2e01 fab in complex with influenza virus neuraminidase from b/phuket/3073/2013 (400 kDa, Complex)
- Beta-d-mannopyranose (180 Da, Ligand)
- Neuraminidase (50 kDa, Protein from Influenza B virus)
- Antibody fab heavy chain (26 kDa, Protein from Homo sapiens)
- Calcium ion (40 Da, Ligand)
- Human antibody (Complex from Homo sapiens)