Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 8odz
Q-score: 0.329
Bloch Y, Felix J, Merceron R, Provost M, Symakani RA, De Backer R, Lambert E, Mehdipour AR, Savvides SN
Nat Struct Mol Biol (2024) 31 pp. 591-597 [ Pubmed: 38287195 DOI: doi:10.1038/s41594-023-01190-6 ]
- Interleukin-12 receptor subunit beta-2,calmodulin-1 (85 kDa, Protein from Mus musculus)
- Interleukin-12 subunit beta (35 kDa, Protein from Mus musculus)
- Water (18 Da, Ligand)
- Interleukin-12 receptor subunit beta-1,death-associated protein kinase 1 (63 kDa, Protein from Mus musculus)
- Interleukin-12 subunit alpha (25 kDa, Protein from Mus musculus)
- Murine il-12 in complex with mil-12rbeta1-dapk1 and mil-12rbeta2-calmodulin. (216 kDa, Complex from Mus musculus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Resolution: 4.6 Å
EM Method: Single-particle
Fitted PDBs: 8oe0
Q-score: 0.208
Bloch Y, Felix J, Merceron R, Provost M, Symakani RA, De Backer R, Lambert E, Mehdipour AR, Savvides SN
Nat Struct Mol Biol (2024) 31 pp. 591-597 [ Pubmed: 38287195 DOI: doi:10.1038/s41594-023-01190-6 ]
- Interleukin-12 receptor subunit beta-2,calmodulin-1 (85 kDa, Protein from Mus musculus)
- Interleukin-12 subunit beta (35 kDa, Protein from Mus musculus)
- Interleukin-12 receptor subunit beta-1,death-associated protein kinase 1 (63 kDa, Protein from Mus musculus)
- Interleukin-12 subunit alpha (25 kDa, Protein from Mus musculus)
- Murine il-12 in complex with mil-12rbeta1-dapk1 and mil-12rbeta2-calmodulin. (216 kDa, Complex from Mus musculus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Cryo-EM structure of a pre-dimerized human IL-23 complete extracellular signaling complex.
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 8oe4
Q-score: 0.294
Bloch Y, Felix J, Merceron R, Provost M, Symakani RA, De Backer R, Lambert E, Mehdipour AR, Savvides SN
Nat Struct Mol Biol (2024) 31 pp. 591-597 [ Pubmed: 38287195 DOI: doi:10.1038/s41594-023-01190-6 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Interleukin-23 subunit alpha (20 kDa, Protein from Homo sapiens)
- Interleukin-12 subunit beta (34 kDa, Protein from Homo sapiens)
- Interleukin-23 receptor,calmodulin-1 (54 kDa, Protein from Homo sapiens)
- Human il-23 in complex with hil-12rbeta1-dapk1 and hil-23r-calmodulin. (168 kDa, Complex from Mus musculus)
- Interleukin-12 receptor subunit beta-1,death-associated protein kinase 1 (60 kDa, Protein from Homo sapiens)
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 8pb1
Q-score: 0.424
Bloch Y, Felix J, Merceron R, Provost M, Symakani RA, De Backer R, Lambert E, Mehdipour AR, Savvides SN
Nat Struct Mol Biol (2024) 31 pp. 591-597 [ Pubmed: 38287195 DOI: doi:10.1038/s41594-023-01190-6 ]
- Interleukin-12 receptor subunit beta-2,calmodulin-1 (85 kDa, Protein from Mus musculus)
- Interleukin-12 subunit beta (35 kDa, Protein from Mus musculus)
- Water (18 Da, Ligand)
- Interleukin-12 receptor subunit beta-1,death-associated protein kinase 1 (63 kDa, Protein from Mus musculus)
- Interleukin-12 subunit alpha (25 kDa, Protein from Mus musculus)
- Murine il-12 in complex with mil-12rbeta1-dapk1 and mil-12rbeta2-calmodulin. (216 kDa, Complex from Mus musculus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
96nm repeat of human respiratory doublet microtubule and associated axonemal complexes
Walton T, Gui M, Velkova S, Fassad MR, Hirst RA, Haarman E, O'Callaghan C, Bottier M, Burgoyne T, Mitchison HM, Brown A
Nature (2023) 618 pp. 625-633 [ Pubmed: 37258679 DOI: doi:10.1038/s41586-023-06140-2 ]
- Piercer of microtubule wall 1 protein (15 kDa, Protein from human)
- Dynein axonemal heavy chain 10 (529 kDa, Protein from human)
- Rib43a-like with coiled-coils protein 2 (45 kDa, Protein from human)
- Dynein axonemal heavy chain 6 (476 kDa, Protein from human)
- Sperm-associated antigen 8 (51 kDa, Protein from human)
- Leucine-rich repeat-containing protein 34 (51 kDa, Protein from human)
- Tektin-2 (49 kDa, Protein from human)
- Cilia- and flagella-associated protein 61 (141 kDa, Protein from human)
- Protein flattop (19 kDa, Protein from human)
- Ef-hand domain-containing protein 1 (74 kDa, Protein from human)
- Cilia- and flagella-associated protein 144 (16 kDa, Protein from human)
- Radial spoke head protein 3 homolog (63 kDa, Protein from human)
- Piercer of microtubule wall 2 protein (13 kDa, Protein from human)
- Dynein axonemal intermediate chain 3 (103 kDa, Protein from human)
- Dynein axonemal heavy chain 7 (461 kDa, Protein from human)
- Protein fam166c (23 kDa, Protein from human)
- Nucleoside diphosphate kinase homolog 5 (24 kDa, Protein from human)
- Cilia- and flagella-associated protein 73 (35 kDa, Protein from human)
- Dynein axonemal intermediate chain 1 (79 kDa, Protein from human)
- Tubulin beta-4b chain (49 kDa, Protein from human)
- Cilia- and flagella-associated protein 299 (26 kDa, Protein from human)
- Dynein axonemal light chain 1 (21 kDa, Protein from human)
- Cilia- and flagella-associated protein 58 (103 kDa, Protein from human)
- Enkurin (29 kDa, Protein from human)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Cilia- and flagella-associated protein 141 (12 kDa, Protein from human)
- Cilia- and flagella-associated protein 100 (71 kDa, Protein from human)
- Radial spoke head 1 homolog (35 kDa, Protein from human)
- Axonemal complex (Complex from Homo sapiens)
- Cilia- and flagella- associated protein 210 (66 kDa, Protein from human)
- Nucleoside diphosphate kinase 7 (42 kDa, Protein from human)
- Dynein axonemal heavy chain 5 (529 kDa, Protein from human)
- Dynein light chain tctex-type protein 2b (16 kDa, Protein from human)
- Ef-hand domain-containing family member c2 (87 kDa, Protein from human)
- Magnesium ion (24 Da, Ligand)
- Cilia- and flagella-associated protein 52 (68 kDa, Protein from human)
- Centrin-2 (19 kDa, Protein from human)
- Outer dynein arm-docking complex subunit 3 (69 kDa, Protein from human)
- Coiled-coil domain-containing protein 39 (110 kDa, Protein from human)
- Radial spoke head protein 9 homolog (31 kDa, Protein from human)
- Cilia- and flagella-associated protein 95 (26 kDa, Protein from human)
- Cilia- and flagella-associated protein 161 (34 kDa, Protein from human)
- Tubulin alpha-1a chain (50 kDa, Protein from human)
- Cilia- and flagella-associated protein 45 (65 kDa, Protein from human)
- Dnaj homolog subfamily b member 13 (36 kDa, Protein from human)
- Rib43a-like with coiled-coils protein 1 (44 kDa, Protein from human)
- Dynein regulatory complex subunit 7 (103 kDa, Protein from human)
- Cilia- and flagella-associated protein 276 (19 kDa, Protein from human)
- Dynll1 (10 kDa, Protein from human)
- Dynein axonemal intermediate chain 7 (83 kDa, Protein from human)
- Uncharacterized protein cfap90 (17 kDa, Protein from human)
- Sperm acrosome-associated protein 9 (25 kDa, Protein from human)
- Outer dynein arm-docking complex subunit 4 (76 kDa, Protein from human)
- Unknown (6 kDa, Protein from human)
- Zinc finger mynd domain-containing protein 12 (41 kDa, Protein from human)
- Calaxin (24 kDa, Protein from human)
- Parkin coregulated gene protein (29 kDa, Protein from human)
- Cilia- and flagella-associated protein 20 (22 kDa, Protein from human)
- Dynein axonemal heavy chain 2 (508 kDa, Protein from human)
- Cilia- and flagella-associated protein 107 (23 kDa, Protein from human)
- Dynein axonemal heavy chain 1 (488 kDa, Protein from human)
- Dynein regulatory complex protein 9 (52 kDa, Protein from human)
- Cilia- and flagella-associated protein 53 (61 kDa, Protein from human)
- Ef-hand domain-containing family member b (93 kDa, Protein from human)
- Coiled-coil domain-containing protein 96 (62 kDa, Protein from human)
- Axonemal dynein light intermediate polypeptide 1 (29 kDa, Protein from human)
- Calmodulin-1 (16 kDa, Protein from human)
- Ropporin-1-like protein (26 kDa, Protein from human)
- Dynein regulatory complex subunit 2 (57 kDa, Protein from human)
- Dynein light chain tctex-type 1 (12 kDa, Protein from human)
- Dynein regulatory complex protein 11 (95 kDa, Protein from human)
- Cilia- and flagella-associated protein 251 (130 kDa, Protein from human)
- Dynein regulatory complex protein 1 (87 kDa, Protein from human)
- Dpy30 domain-containing protein 2 (20 kDa, Protein from human)
- Dynein axonemal intermediate chain 4 (94 kDa, Protein from human)
- Protein fam166b (30 kDa, Protein from human)
- Dynein light chain roadblock-type 2 (10 kDa, Protein from human)
- Thioredoxin domain-containing protein 6 (36 kDa, Protein from human)
- Dynein axonemal intermediate chain 2 (68 kDa, Protein from human)
- Dynein axonemal heavy chain 9 (512 kDa, Protein from human)
- Uncharacterized protein cfap68 (17 kDa, Protein from human)
- Cilia- and flagella-associated protein 91 (90 kDa, Protein from human)
- Dynein regulatory complex subunit 4 (56 kDa, Protein from human)
- Tetratricopeptide repeat protein 29 (55 kDa, Protein from human)
- Coiled-coil domain-containing protein 40 (130 kDa, Protein from human)
- Cilia- and flagella-associated protein 77 (33 kDa, Protein from human)
- Morn repeat-containing protein 3 (27 kDa, Protein from human)
- Probable inactive peptidyl-prolyl cis-trans isomerase-like 6 (35 kDa, Protein from human)
- Cytochrome b5 domain-containing protein 1 (26 kDa, Protein from human)
- Acta2 (42 kDa, Protein from human)
- Tektin-1 (48 kDa, Protein from human)
- Coiled-coil domain-containing protein 113 (44 kDa, Protein from human)
- Guanosine-5'-diphosphate (443 Da, Ligand)
- Cilia- and flagella-associated protein 43 (192 kDa, Protein from human)
- Outer dynein arm-docking complex subunit 2 (115 kDa, Protein from human)
- Dynein regulatory complex protein 10 (52 kDa, Protein from human)
- Iq and ubiquitin-like domain-containing protein (92 kDa, Protein from human)
- Sperm surface protein sp17 (17 kDa, Protein from human)
- Radial spoke head protein 4 homolog a (80 kDa, Protein from human)
- Dynein axonemal heavy chain 12 (454 kDa, Protein from human)
- Meiosis-specific nuclear structural protein 1 (60 kDa, Protein from human)
- Radial spoke head 14 homolog (38 kDa, Protein from human)
- Dynein regulatory complex subunit 3 (61 kDa, Protein from human)
- Cilia- and flagella-associated protein 44 (214 kDa, Protein from human)
- Dynein regulatory complex subunit 5 (55 kDa, Protein from human)
- Dynein axonemal heavy chain 3 (471 kDa, Protein from human)
- Dynein regulatory complex protein 8 (29 kDa, Protein from human)
- Outer dynein arm-docking complex subunit 1 (75 kDa, Protein from human)
- Dynein light chain roadblock-type 1 (10 kDa, Protein from human)
- Cilia- and flagella-associated protein 57 (145 kDa, Protein from human)
Calmodulin-bound full-length rbTRPV5
Resolution: 4.4 Å
EM Method: Single-particle
Fitted PDBs: 6dmw
Q-score: 0.356
Hughes TET, Pumroy RA, Yazici AT, Kasimova MA, Fluck EC, Huynh KW, Samanta A, Molugu SK, Zhou ZH, Carnevale V, Rohacs T, Moiseenkova-Bell VY
Nat Commun (2018) 9 pp. 4198-4198 [ DOI: doi:10.1038/s41467-018-06753-6 Pubmed: 30305626 ]
- Calmodulin-bound rbtrpv5 tetramer (Complex)
- Calmodulin-1 (16 kDa, Protein from Rattus norvegicus)
- Transient receptor potential cation channel subfamily v member 5 (82 kDa, Protein from Oryctolagus cuniculus)
- Rbtrpv5 tetramer (Complex from Oryctolagus cuniculus)
- Rat calmodulin (Complex from Rattus norvegicus)
- Calcium ion (40 Da, Ligand)