Cryo-EM structure of Myosin VI in the autoinhibited state (without SAH-extension density)
Resolution: 3.54 Å
EM Method: Single-particle
Fitted PDBs: 8w41
Q-score: 0.34
Niu F, Li L, Wang L, Xiao J, Xu S, Liu Y, Lin L, Yu C, Wei Z
Nat Commun (2024) 15 pp. 1187-1187 [ DOI: doi:10.1038/s41467-024-45424-7 Pubmed: 38331992 ]
- Complex of myosin vi and calmodulin (Complex)
- Unconventional myosin-vi (148 kDa, Protein from Homo sapiens)
- Phosphate ion (94 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Calmodulin-1 (16 kDa, Protein from Mus musculus)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Myosin vi (Complex from Homo sapiens)
- Calmodulin (Complex from Mus musculus)
- Calcium ion (40 Da, Ligand)
Cryo-EM structure of full-length Myosin Va in the autoinhibited state
Resolution: 4.78 Å
EM Method: Single-particle
Fitted PDBs: 7yv9
Q-score: 0.189
Niu F, Liu Y, Sun K, Xu S, Dong J, Yu C, Yan K, Wei Z
Sci Adv (2022) 8 pp. eadd4187-eadd4187 [ DOI: doi:10.1126/sciadv.add4187 Pubmed: 36490350 ]
- Unconventional myosin-va (212 kDa, Protein from Mus musculus)
- Myosin va and calmodulin complex (630 kDa, Complex from Mus musculus)
- Calmodulin-1 (16 kDa, Protein from Mus musculus)
Structure of RyR2 (F/apoCaM dataset)
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 6ji8
Q-score: 0.384
Gong D, Chi X, Wei J, Zhou G, Huang G, Zhang L, Wang R, Lei J, Chen SRW, Yan N
Nature (2019) 572 pp. 347-351 [ Pubmed: 31278385 DOI: doi:10.1038/s41586-019-1377-y ]
- Peptidyl-prolyl cis-trans isomerase fkbp1b (11 kDa, Protein from Homo sapiens)
- Ryr2 (564 kDa, Protein from Sus scrofa)
- Zinc ion (65 Da, Ligand)
- Ryr2 in complex with fkbp12.6 and apo-calmodulin (Complex from Sus scrofa)
- Calmodulin-1 (16 kDa, Protein from Homo sapiens)
Structure of RyR2 (F/A/C/L-Ca2+/apo-CaM-M dataset)
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 6jii
Q-score: 0.319
Gong D, Chi X, Wei J, Zhou G, Huang G, Zhang L, Wang R, Lei J, Chen SRW, Yan N
Nature (2019) 572 pp. 347-351 [ Pubmed: 31278385 DOI: doi:10.1038/s41586-019-1377-y ]
- Peptidyl-prolyl cis-trans isomerase fkbp1b (11 kDa, Protein from Homo sapiens)
- Calmodulin-1 (16 kDa, Protein from Homo sapiens)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Ryr2 (564 kDa, Protein from Sus scrofa)
- Zinc ion (65 Da, Ligand)
- Caffeine (194 Da, Ligand)
- Calcium ion (40 Da, Ligand)
- Ryr2 in complex with fkbp12.6 and apo-calmodulin-mimicking mutant (Complex from Sus scrofa)
Structure of RyR2 (F/A/C/L-Ca2+/Ca2+CaM dataset)
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 6jiu
Q-score: 0.303
Gong D, Chi X, Wei J, Zhou G, Huang G, Zhang L, Wang R, Lei J, Chen SRW, Yan N
Nature (2019) 572 pp. 347-351 [ Pubmed: 31278385 DOI: doi:10.1038/s41586-019-1377-y ]
- Peptidyl-prolyl cis-trans isomerase fkbp1b (11 kDa, Protein from Homo sapiens)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Ryr2 (564 kDa, Protein from Sus scrofa)
- Zinc ion (65 Da, Ligand)
- Ryr2 in complex with fkbp12.6 and ca2+-loaded calmodulin at low ca2+ concentrations (Complex from Sus scrofa)
- Caffeine (194 Da, Ligand)
- Calcium ion (40 Da, Ligand)
- Calmodulin-1 (16 kDa, Protein from Homo sapiens)
Structure of RyR2 (F/A/C/H-Ca2+/Ca2+CaM dataset)
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 6jiy
Q-score: 0.375
Gong D, Chi X, Wei J, Zhou G, Huang G, Zhang L, Wang R, Lei J, Chen SRW, Yan N
Nature (2019) 572 pp. 347-351 [ Pubmed: 31278385 DOI: doi:10.1038/s41586-019-1377-y ]
- Peptidyl-prolyl cis-trans isomerase fkbp1b (11 kDa, Protein from Homo sapiens)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Ryr2 (564 kDa, Protein from Sus scrofa)
- Zinc ion (65 Da, Ligand)
- Caffeine (194 Da, Ligand)
- Calcium ion (40 Da, Ligand)
- Ryr2 in complex with fkbp12.6 and ca2+-loaded calmodulin at high ca2+ concentrations (Complex from Sus scrofa)
- Calmodulin-1 (16 kDa, Protein from Homo sapiens)
Structure of RyR2 (*F/A/C/L-Ca2+/Ca2+-CaM dataset)
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 6jrs
Q-score: 0.421
Gong D, Chi X, Wei J, Zhou G, Huang G, Zhang L, Wang R, Lei J, Chen SRW, Yan N
Nature (2019) 572 pp. 347-351 [ Pubmed: 31278385 DOI: doi:10.1038/s41586-019-1377-y ]
- Peptidyl-prolyl cis-trans isomerase fkbp1b (11 kDa, Protein from Homo sapiens)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Ryr2 (564 kDa, Protein from Sus scrofa)
- Zinc ion (65 Da, Ligand)
- Caffeine (194 Da, Ligand)
- Ryr2 in complex with fkbp12.6 and calmodulin (Complex from Sus scrofa)
- Calcium ion (40 Da, Ligand)
- Calmodulin-1 (16 kDa, Protein from Homo sapiens)
Structure of RyR2 (P/L-Ca2+/Ca2+-CaM dataset)
Resolution: 4.4 Å
EM Method: Single-particle
Fitted PDBs: 6jv2
Q-score: 0.267
Gong D, Chi X, Wei J, Zhou G, Huang G, Zhang L, Wang R, Lei J, Chen SRW, Yan N
Nature (2019) 572 pp. 347-351 [ Pubmed: 31278385 DOI: doi:10.1038/s41586-019-1377-y ]
- Ryr2 in complex with calmodulin (Complex from Sus scrofa)
- Ryr2 (564 kDa, Protein from Sus scrofa)
- Zinc ion (65 Da, Ligand)
- Calcium ion (40 Da, Ligand)
- Calmodulin-1 (16 kDa, Protein from Homo sapiens)