Structure of Fanconi anaemia core complex (consensus map)
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 6sri
Q-score: 0.112
Shakeel S, Rajendra E, Alcon P, O'Reilly F, Chorev DS, Maslen S, Degliesposti G, Russo CJ, He S, Hill CH, Skehel JM, Scheres SHW, Patel KJ, Rappsilber J, Robinson CV, Passmore LA
Nature (2019) 575 pp. 234-237 [ DOI: doi:10.1038/s41586-019-1703-4 Pubmed: 31666700 ]
- Unassigned secondary structure elements (central region, proposed fancb-faap100) (1 kDa, Protein from Gallus gallus)
- Unassigned secondary structure elements (base region, proposed fancc-fanc-e-fancf) (1 kDa, Protein from Gallus gallus)
- Unassigned secondary structure elements (proposed faap100) (3 kDa, Protein from Gallus gallus)
- Fanconi anaemia protein fancl (42 kDa, Protein from Gallus gallus)
- Unassigned secondary structure elements (proposed fancb) (10 kDa, Protein from Gallus gallus)
- Unassigned secondary structure elements (central region, proposed fancb-faap100) (2 kDa, Protein from Gallus gallus)
- Unassigned secondary structure elements (central region, proposed fancb-faap100) (783 Da, Protein from Gallus gallus)
- Unassigned secondary structure elements (proposed faap100) (23 kDa, Protein from Gallus gallus)
- Unassigned secondary structure elements (central region, proposed fancb-faap100) (3 kDa, Protein from Gallus gallus)
- Base region, proposed fancf (17 kDa, Protein from Gallus gallus)
- Unassigned secondary structure elements (proposed fancb) (23 kDa, Protein from Gallus gallus)
- Unassigned secondary structure elements (base region, proposed fancc-fanc-e-fancf) (6 kDa, Protein from Gallus gallus)
- Unassigned secondary structure elements (top region, proposed fancg) (24 kDa, Protein from Gallus gallus)
- Unassigned secondary structure elements (central region, proposed fancb-faap100) (1 kDa, Protein from Gallus gallus)
- Unassigned secondary structure elements (central region, proposed fancb-faap100) (1 kDa, Protein from Gallus gallus)
- Unassigned secondary structure elements (base region, proposed fancc-fanc-e-fancf) (1 kDa, Protein from Gallus gallus)
- Unassigned secondary structure elements (base region, proposed fancc-fanc-e-fancf) (5 kDa, Protein from Gallus gallus)
- Unassigned secondary structure elements (central region, proposed fancb-faap100: chain f,f; base region, proposed fancc-fanc-e-fancf: chain z) (1 kDa, Protein from Gallus gallus)
- Unassigned secondary structure elements (central region, proposed fancb-faap100) (1 kDa, Protein from Gallus gallus)
- Fanconi anaemia core complex (860 kDa, Complex from Gallus gallus)
- Unassigned secondary structure elements (base region, proposed fancc-fanc-e-fancf) (2 kDa, Protein from Gallus gallus)
- Unassigned secondary structure elements (central region, proposed fancb-faap100) (2 kDa, Protein from Gallus gallus)
- Unassigned secondary structure elements (base region, proposed fancc-fanc-e-fancf) (7 kDa, Protein from Gallus gallus)
- Unassigned secondary structure elements (central region, proposed fancb-faap100: chain a,a; base region, proposed fancc-fanc-e-fancf: chain 3) (6 kDa, Protein from Gallus gallus)
- Unassigned secondary structure elements (central region, proposed fancb-faap100) (2 kDa, Protein from Gallus gallus)
- Unassigned secondary structure elements (base region, proposed fancc-fanc-e-fancf) (9 kDa, Protein from Gallus gallus)
- Unassigned secondary structure elements (top region, proposed fancg) (12 kDa, Protein from Gallus gallus)
- Unassigned secondary structure elements (base region, proposed fancc-fanc-e-fancf) (19 kDa, Protein from Gallus gallus)
Structure of the Fanconi Anaemia core complex (focussed map for top region)
Shakeel S, Rajendra E, Alcon P, O'Reilly F, Chorev DS, Maslen S, Degliesposti G, Russo CJ, He S, Hill CH, Skehel JM, Scheres SHW, Patel KJ, Rappsilber J, Robinson CV, Passmore LA
Nature (2019) 575 pp. 234-237 [ DOI: doi:10.1038/s41586-019-1703-4 Pubmed: 31666700 ]
- Fanconi anaemia core complex (860 kDa, Complex from Gallus gallus)
Structure of the Fanconi Anaemia core complex (focussed map for middle region)
Shakeel S, Rajendra E, Alcon P, O'Reilly F, Chorev DS, Maslen S, Degliesposti G, Russo CJ, He S, Hill CH, Skehel JM, Scheres SHW, Patel KJ, Rappsilber J, Robinson CV, Passmore LA
Nature (2019) 575 pp. 234-237 [ DOI: doi:10.1038/s41586-019-1703-4 Pubmed: 31666700 ]
- Fanconi anaemia core complex (860 kDa, Complex from Gallus gallus)
Structure of the Fanconi Anaemia core complex (focussed map for base region)
Shakeel S, Rajendra E, Alcon P, O'Reilly F, Chorev DS, Maslen S, Degliesposti G, Russo CJ, He S, Hill CH, Skehel JM, Scheres SHW, Patel KJ, Rappsilber J, Robinson CV, Passmore LA
Nature (2019) 575 pp. 234-237 [ DOI: doi:10.1038/s41586-019-1703-4 Pubmed: 31666700 ]
- Fanconi anaemia core complex (860 kDa, Complex from Gallus gallus)
Structure of the Fanconi anaemia core subcomplex
Resolution: 4.6 Å
EM Method: Single-particle
Fitted PDBs: 6srs
Q-score: 0.135
Shakeel S, Rajendra E, Alcon P, O'Reilly F, Chorev DS, Maslen S, Degliesposti G, Russo CJ, He S, Hill CH, Skehel JM, Scheres SHW, Patel KJ, Rappsilber J, Robinson CV, Passmore LA
Nature (2019) 575 pp. 234-237 [ DOI: doi:10.1038/s41586-019-1703-4 Pubmed: 31666700 ]
- Unassigned secondary structure elements (central region, proposed fancb-faap100) (1 kDa, Protein from Gallus gallus)
- Unassigned secondary structure elements (proposed faap100) (3 kDa, Protein from Gallus gallus)
- Unassigned secondary structure elements (proposed fancb) (10 kDa, Protein from Gallus gallus)
- Unassigned secondary structure elements (central region, proposed fancb-faap100) (2 kDa, Protein from Gallus gallus)
- Unassigned secondary structure elements (central region, proposed fancb-faap100) (783 Da, Protein from Gallus gallus)
- Unassigned secondary structure elements (proposed faap100) (23 kDa, Protein from Gallus gallus)
- Unassigned secondary structure elements (central region, proposed fancb-faap100) (3 kDa, Protein from Gallus gallus)
- Unassigned secondary structure elements (proposed fancb) (23 kDa, Protein from Gallus gallus)
- Unassigned secondary structure elements (central region, proposed fancb-faap100) (1 kDa, Protein from Gallus gallus)
- Unassigned secondary structure elements (central region, proposed fancb-faap100) (1 kDa, Protein from Gallus gallus)
- Unassigned secondary structure elements (proposed fancg) (12 kDa, Protein from Gallus gallus)
- Unassigned secondary structure elements (central region, proposed fancb-faap100) (1 kDa, Protein from Gallus gallus)
- Fanconi anaemia protein fancl (10 kDa, Protein from Gallus gallus)
- Fanconi anaemia core subcomplex (860 kDa, Complex from Gallus gallus)
- Unassigned secondary structure elements (central region, proposed fancb-faap100) (2 kDa, Protein from Gallus gallus)
- Unassigned secondary structure elements (central region, proposed fancb-faap100) (1 kDa, Protein from Gallus gallus)
- Unassigned secondary structure elements (central region, proposed fancb-faap100) (2 kDa, Protein from Gallus gallus)
- Unassigned secondary structure elements (central region, proposed fancb-faap100) (6 kDa, Protein from Gallus gallus)
- Unassigned secondary structure elements (proposed fancg) (24 kDa, Protein from Gallus gallus)
Structure of the ESX-3 core complex
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 6sgw
Q-score: 0.427
Famelis N, Rivera-Calzada A, Degliesposti G, Wingender M, Mietrach N, Skehel JM, Fernandez-Leiro R, Bottcher B, Schlosser A, Llorca O, Geibel S
Nature (2019) 576 pp. 321-325 [ DOI: doi:10.1038/s41586-019-1633-1 Pubmed: 31597161 ]
- Esx-3 secretion system protein ecce3 (30 kDa, Protein from Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155))
- Esx-3 secretion system atpase eccb3 (9 kDa, Protein from Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155))
- Esx-3 secretion system protein eccd3 (47 kDa, Protein from Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155))
- Esx-3 secretion system protein eccc3 (44 kDa, Protein from Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155))
- Esx-3 core complex (650 kDa, Complex from Mycolicibacterium smegmatis MC2 155)
Structure of protomer 1 of the ESX-3 core complex
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 6sgx
Q-score: 0.478
Famelis N, Rivera-Calzada A, Degliesposti G, Wingender M, Mietrach N, Skehel JM, Fernandez-Leiro R, Bottcher B, Schlosser A, Llorca O, Geibel S
Nature (2019) 576 pp. 321-325 [ DOI: doi:10.1038/s41586-019-1633-1 Pubmed: 31597161 ]
- Esx-3 secretion system protein ecce3 (30 kDa, Protein from Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155))
- Esx-3 secretion system protein eccd3 (47 kDa, Protein from Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155))
- Protomer1 of the esx-3 core complex (650 kDa, Complex from Mycolicibacterium smegmatis MC2 155)
- Esx-3 secretion system protein eccc3 (44 kDa, Protein from Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155))
- Esx-3 secretion system eccb3 (8 kDa, Protein from Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155))
ESX-3 core complex centred at the cytoplasmic region, conformation 1.
Famelis N, Rivera-Calzada A, Degliesposti G, Wingender M, Mietrach N, Skehel JM, Fernandez-Leiro R, Bottcher B, Schlosser A, Llorca O, Geibel S
Nature (2019) 576 pp. 321-325 [ DOI: doi:10.1038/s41586-019-1633-1 Pubmed: 31597161 ]
- Ecce3 (Protein from Mycolicibacterium smegmatis MC2 155)
- Esx-3 core complex, conformation 1 (650 kDa, Complex from Mycolicibacterium smegmatis MC2 155)
- Eccc3 (Protein from Mycolicibacterium smegmatis MC2 155)
- Eccd3 (Protein from Mycolicibacterium smegmatis MC2 155)
- Eccb3 (Protein from Mycolicibacterium smegmatis MC2 155)
ESX-3 core complex centred at the cytoplasmic region, conformation 2.
Famelis N, Rivera-Calzada A, Degliesposti G, Wingender M, Mietrach N, Skehel JM, Fernandez-Leiro R, Bottcher B, Schlosser A, Llorca O, Geibel S
Nature (2019) 576 pp. 321-325 [ DOI: doi:10.1038/s41586-019-1633-1 Pubmed: 31597161 ]
- Esx-3 core complex, conformation 2 (650 kDa, Complex from Mycolicibacterium smegmatis MC2 155)
- Ecce3 (Protein from Mycolicibacterium smegmatis MC2 155)
- Eccc3 (Protein from Mycolicibacterium smegmatis MC2 155)
- Eccd3 (Protein from Mycolicibacterium smegmatis MC2 155)
- Eccb3 (Protein from Mycolicibacterium smegmatis MC2 155)
Structure of protomer 2 of the ESX-3 core complex
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 6sgz
Q-score: 0.42
Famelis N, Rivera-Calzada A, Degliesposti G, Wingender M, Mietrach N, Skehel JM, Fernandez-Leiro R, Bottcher B, Schlosser A, Llorca O, Geibel S
Nature (2019) 576 pp. 321-325 [ DOI: doi:10.1038/s41586-019-1633-1 Pubmed: 31597161 ]
- Esx-3 secretion system protein eccd3 (Complex from Mycolicibacterium smegmatis MC2 155)
- Esx-3 secretion system protein eccc3 (Complex from Mycolicibacterium smegmatis MC2 155)
- Esx-3 secretion system atpase eccb3 (6 kDa, Protein from Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155))
- Esx-3 secretion system protein ecce3 (30 kDa, Protein from Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155))
- Esx-3 secretion system protein eccb3 (Complex from Mycolicibacterium smegmatis MC2 155)
- Protomer2 of the esx-3 core complex (650 kDa, Complex)
- Esx-3 secretion system protein eccd3 (47 kDa, Protein from Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155))
- Esx-3 secretion system protein eccc3 (38 kDa, Protein from Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155))