Structure of the Fanconi Anaemia core complex (focussed map for top region)
Shakeel S, Rajendra E, Alcon P, O'Reilly F, Chorev DS, Maslen S, Degliesposti G, Russo CJ, He S, Hill CH, Skehel JM, Scheres SHW, Patel KJ, Rappsilber J, Robinson CV, Passmore LA
Nature (2019) 575 pp. 234-237 [ DOI: doi:10.1038/s41586-019-1703-4 Pubmed: 31666700 ]
- Fanconi anaemia core complex (860 kDa, Complex from Gallus gallus)
Structure of the Fanconi Anaemia core complex (focussed map for middle region)
Shakeel S, Rajendra E, Alcon P, O'Reilly F, Chorev DS, Maslen S, Degliesposti G, Russo CJ, He S, Hill CH, Skehel JM, Scheres SHW, Patel KJ, Rappsilber J, Robinson CV, Passmore LA
Nature (2019) 575 pp. 234-237 [ DOI: doi:10.1038/s41586-019-1703-4 Pubmed: 31666700 ]
- Fanconi anaemia core complex (860 kDa, Complex from Gallus gallus)
Structure of the Fanconi Anaemia core complex (focussed map for base region)
Shakeel S, Rajendra E, Alcon P, O'Reilly F, Chorev DS, Maslen S, Degliesposti G, Russo CJ, He S, Hill CH, Skehel JM, Scheres SHW, Patel KJ, Rappsilber J, Robinson CV, Passmore LA
Nature (2019) 575 pp. 234-237 [ DOI: doi:10.1038/s41586-019-1703-4 Pubmed: 31666700 ]
- Fanconi anaemia core complex (860 kDa, Complex from Gallus gallus)
ESX-3 core complex centred at the cytoplasmic region, conformation 1.
Famelis N, Rivera-Calzada A, Degliesposti G, Wingender M, Mietrach N, Skehel JM, Fernandez-Leiro R, Bottcher B, Schlosser A, Llorca O, Geibel S
Nature (2019) 576 pp. 321-325 [ DOI: doi:10.1038/s41586-019-1633-1 Pubmed: 31597161 ]
- Ecce3 (Protein from Mycolicibacterium smegmatis MC2 155)
- Esx-3 core complex, conformation 1 (650 kDa, Complex from Mycolicibacterium smegmatis MC2 155)
- Eccc3 (Protein from Mycolicibacterium smegmatis MC2 155)
- Eccd3 (Protein from Mycolicibacterium smegmatis MC2 155)
- Eccb3 (Protein from Mycolicibacterium smegmatis MC2 155)
ESX-3 core complex centred at the cytoplasmic region, conformation 2.
Famelis N, Rivera-Calzada A, Degliesposti G, Wingender M, Mietrach N, Skehel JM, Fernandez-Leiro R, Bottcher B, Schlosser A, Llorca O, Geibel S
Nature (2019) 576 pp. 321-325 [ DOI: doi:10.1038/s41586-019-1633-1 Pubmed: 31597161 ]
- Esx-3 core complex, conformation 2 (650 kDa, Complex from Mycolicibacterium smegmatis MC2 155)
- Ecce3 (Protein from Mycolicibacterium smegmatis MC2 155)
- Eccc3 (Protein from Mycolicibacterium smegmatis MC2 155)
- Eccd3 (Protein from Mycolicibacterium smegmatis MC2 155)
- Eccb3 (Protein from Mycolicibacterium smegmatis MC2 155)
Ovine respiratory supercomplex I+III2 open class 2
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 6qc2
Q-score: 0.36
Letts JA, Fiedorczuk K, Degliesposti G, Skehel M, Sazanov LA
Mol Cell (2019) 75 pp. 1131-1146.e6 [ Pubmed: 31492636 DOI: doi:10.1016/j.molcel.2019.07.022 ]
- Uqcrb (13 kDa, Protein from Ovis aries)
- Nadh:ubiquinone oxidoreductase subunit b2 (8 kDa, Protein from Sheep)
- Ndufs7 (20 kDa, Protein from Ovis aries)
- Nadh:ubiquinone oxidoreductase subunit b4 (14 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit b7 (14 kDa, Protein from Sheep)
- Ubiquinol-cytochrome c reductase complex iii subunit vii (9 kDa, Protein from Sheep)
- Flavin mononucleotide (456 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from Sheep)
- Ndufa13 (16 kDa, Protein from Ovis aries)
- Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from Sheep)
- Ndufs2 (49 kDa, Protein from Ovis aries)
- Ndufs8 (20 kDa, Protein from Ovis aries)
- Nadh:ubiquinone oxidoreductase subunit b9 (21 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit s4 (15 kDa, Protein from Sheep)
- Ndufa7 (12 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit a9 (38 kDa, Protein from Sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from Sheep)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 1 (35 kDa, Protein from Sheep)
- Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from Sheep)
- Ndufb6 (15 kDa, Protein from Sheep)
- Ndufc1 (5 kDa, Protein from Ovis aries)
- Ndufb1 (6 kDa, Protein from Sheep)
- Ndufa5 (13 kDa, Protein from Sheep)
- Ndufs6 (10 kDa, Protein from Ovis aries)
- Nadh:ubiquinone oxidoreductase subunit b3 (11 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase core subunit s3 (26 kDa, Protein from Sheep)
- Ndufv3 (8 kDa, Protein from Ovis aries)
- Nadh-ubiquinone oxidoreductase chain 4 (52 kDa, Protein from Sheep)
- Ndufa1 (8 kDa, Protein from Ovis aries)
- 1,2-diacyl-sn-glycero-3-phosphoethanolamine (748 Da, Ligand)
- Iron/sulfur cluster (351 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 6 (19 kDa, Protein from Sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (10 kDa, Protein from Sheep)
- Acyl carrier protein (10 kDa, Protein from Sheep)
- Uqcrfs1n (6 kDa, Protein from Ovis aries)
- Nadh-ubiquinone oxidoreductase chain 3 (13 kDa, Protein from Sheep)
- Ndufb11 (14 kDa, Protein from Sheep)
- Ndufa11 (14 kDa, Protein from Sheep)
- Ndufv2 (23 kDa, Protein from Sheep)
- Ubiquinol-cytochrome c reductase core protein 2 (46 kDa, Protein from Sheep)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Cardiolipin (1 kDa, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (18 kDa, Protein from Sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (20 kDa, Protein from Sheep)
- Heme c (618 Da, Ligand)
- Protoporphyrin ix containing fe (616 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Nadh:ubiquinone oxidoreductase subunit a6 (14 kDa, Protein from Sheep)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (48 kDa, Protein from Sheep)
- Ovine mitochondrial respiratory supercomplex i+iii2 (1 MDa, Complex from Ovis aries)
- Ubiquinol-cytochrome c reductase, complex iii subunit x (7 kDa, Protein from Sheep)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (36 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit a3 (9 kDa, Protein from Sheep)
- Uqcrc1 (49 kDa, Protein from Ovis aries)
- Cytochrome b (42 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit b5 (16 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase core subunit s1 (77 kDa, Protein from Sheep)
- Ndufb10 (20 kDa, Protein from Ovis aries)
- Nadh-ubiquinone oxidoreductase chain 2 (39 kDa, Protein from Sheep)
- Uqcrqh (9 kDa, Protein from Ovis aries)
- Cytochrome b-c1 complex subunit rieske, mitochondrial (21 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit s5 (12 kDa, Protein from Sheep)
- S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
- Cytochrome c1 (27 kDa, Protein from Sheep)