Uncrosslinked VRK1-nucleosome complex
Budziszewski GR, Zhao Y, Spangler CJ, Kedziora KM, Williams MR, Azzam DN, Skrajna A, Koyama Y, Cesmat AP, Simmons HC, Arteaga EC, Strauss JD, Kireev D, McGinty RK
Nucleic Acids Res (2022) 50 pp. 4355-4371 [ Pubmed: 35390161 DOI: doi:10.1093/nar/gkac198 ]
- Histone h3.2 (Protein from Homo sapiens)
- Structure of vrk1 c-terminal tail bound to nucleosome core particle (Complex)
- Widom 601 dna (185-mer) (DNA from synthetic construct)
- Vaccinia-related kinase 1 (Protein from Homo sapiens)
- Histone h3.2, histone h4, histone h2a type 1, histone h2b type 1-c/e/f/g/i, serine/threonine-protein kinase vrk1 (Complex from Homo sapiens)
- Histone h2a (Protein from Homo sapiens)
- Histone h4 (Protein from Homo sapiens)
- Dna (Complex from synthetic construct)
- Histone h2b (Protein from Homo sapiens)
Hepatitis B core protein with low secretion phenotype (P5T) and bound GSLLGRMKGA
Makbul C, Khayenko V, Maric HM, Bottcher B
Microorganisms (2021) 9 [ DOI: doi:10.3390/microorganisms9050956 Pubmed: 33946808 ]
- Peptide gsllgrmkga (Protein from synthetic construct)
- Hepatitis b core protein (Protein from Hepatitis B virus)
- Hepatitis b virus (4 MDa, Virus from Hepatitis B virus)
Hepatitis B core protein capsid, mutant F97L with bound MHRSLLGRMKGA
Makbul C, Khayenko V, Maric HM, Bottcher B
Microorganisms (2021) 9 [ DOI: doi:10.3390/microorganisms9050956 Pubmed: 33946808 ]
- Peptide mhrsllgrmkga (Protein from synthetic construct)
- Hepatitis b core protein (Protein from Hepatitis B virus)
- Hepatitis b virus (4 MDa, Virus from Hepatitis B virus)
Hepatitis B core Protein, F97L - premature secretion mutant with bound GSLLGRMKGA
Makbul C, Khayenko V, Maric HM, Bottcher B
Microorganisms (2021) 9 [ DOI: doi:10.3390/microorganisms9050956 Pubmed: 33946808 ]
- Peptide gsllgrmkga (Protein from synthetic construct)
- Hepatitis b core protein (Protein from Hepatitis B virus)
- Hepatitis b virus (4 MDa, Virus from Hepatitis B virus)
Complex I during turnover, open3
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 6zkf
Q-score: 0.564
Science (2020) 370 [ Pubmed: 32972993 DOI: doi:10.1126/science.abc4209 ]
- Flavin mononucleotide (456 Da, Ligand)
- Potassium ion (39 Da, Ligand)
- Nadh:ubiquinone oxidoreductase subunit b4 (15 kDa, Protein from Sheep)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from Sheep)
- Mitochondrial complex i, mnll subunit (7 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit a3 (9 kDa, Protein from Sheep)
- Nadh-ubiquinone oxidoreductase chain 1 (35 kDa, Protein from Sheep)
- Nadh-ubiquinone oxidoreductase chain 4 (52 kDa, Protein from Sheep)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (50 kDa, Protein from Sheep)
- Iron/sulfur cluster (351 Da, Ligand)
- 1,2-diacyl-sn-glycero-3-phosphoethanolamine (748 Da, Ligand)
- Mitochondrial complex i, kfyi subunit (8 kDa, Protein from Sheep)
- Nadh-ubiquinone oxidoreductase chain 6 (19 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit b9 (21 kDa, Protein from Sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (11 kDa, Protein from Sheep)
- Mitochondrial complex i, 49 kda subunit (52 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase core subunit s3 (30 kDa, Protein from Sheep)
- Mitochondrial complex i, pdsw subunit (20 kDa, Protein from Sheep)
- Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from Sheep)
- Mitochondrial complex i, b14.7 subunit (14 kDa, Protein from Sheep)
- Mitochondrial complex i, psst subunit (24 kDa, Protein from Sheep)
- Mitochondrial complex i, mwfe subunit (8 kDa, Protein from Sheep)
- Nadh-ubiquinone oxidoreductase chain 3 (13 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase core subunit s1 (79 kDa, Protein from Sheep)
- Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from Sheep)
- Mitochondrial complex i, tyky subunit (24 kDa, Protein from Sheep)
- Adenosine monophosphate (347 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (20 kDa, Protein from Sheep)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Cardiolipin (1 kDa, Ligand)
- Nadh:ubiquinone oxidoreductase subunit b7 (16 kDa, Protein from Sheep)
- Mitochondrial complex i, b13 subunit (13 kDa, Protein from Sheep)
- Zinc ion (65 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (40 kDa, Protein from Sheep)
- Mitochondrial complex i, b17 subunit (15 kDa, Protein from Sheep)
- Complex i during turnover, open3 (1 MDa, Complex from Ovis aries)
- Acyl carrier protein (17 kDa, Protein from Sheep)
- Mitochondrial complex i, 13 kda subunit (13 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit b3 (11 kDa, Protein from Sheep)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (21 kDa, Protein from Sheep)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Mitochondrial complex i, b14.5a subunit (12 kDa, Protein from Sheep)
- Mitochondrial complex i, 10 kda subunit (11 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit a9 (43 kDa, Protein from Sheep)
- Myristic acid (228 Da, Ligand)
- 2-decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione (322 Da, Ligand)
- 1,4-dihydronicotinamide adenine dinucleotide (665 Da, Ligand)
- Mitochondrial complex i, 24 kda subunit (27 kDa, Protein from Sheep)
- Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from Sheep)
- Mitochondrial complex i, b16.6 subunit (16 kDa, Protein from Sheep)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (19 kDa, Protein from Sheep)
- Nadh-ubiquinone oxidoreductase chain 2 (39 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit s5 (12 kDa, Protein from Sheep)
- Mitochondrial complex i, esss subunit (17 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit a6 (16 kDa, Protein from Sheep)
- S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
- Nadh:ubiquinone oxidoreductase subunit b2 (12 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit b5 (21 kDa, Protein from Sheep)
Peripheral domain of open complex I during turnover
Resolution: 2.3 Å
EM Method: Single-particle
Fitted PDBs: 6zk9
Q-score: 0.66
Science (2020) 370 [ Pubmed: 32972993 DOI: doi:10.1126/science.abc4209 ]
- Flavin mononucleotide (456 Da, Ligand)
- Potassium ion (39 Da, Ligand)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from Sheep)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (50 kDa, Protein from Sheep)
- Iron/sulfur cluster (351 Da, Ligand)
- 1,2-diacyl-sn-glycero-3-phosphoethanolamine (748 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (11 kDa, Protein from Sheep)
- Mitochondrial complex i, 49 kda subunit (52 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase core subunit s3 (30 kDa, Protein from Sheep)
- Mitochondrial complex i, psst subunit (24 kDa, Protein from Sheep)
- Peripheral domain of open complex i during turnover (1 MDa, Complex from Ovis aries)
- Nadh:ubiquinone oxidoreductase core subunit s1 (79 kDa, Protein from Sheep)
- Mitochondrial complex i, tyky subunit (24 kDa, Protein from Sheep)
- Cardiolipin (1 kDa, Ligand)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Mitochondrial complex i, b13 subunit (13 kDa, Protein from Sheep)
- Zinc ion (65 Da, Ligand)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Mitochondrial complex i, 13 kda subunit (13 kDa, Protein from Sheep)
- Acyl carrier protein (17 kDa, Protein from Sheep)
- Mitochondrial complex i, b14.5a subunit (12 kDa, Protein from Sheep)
- Mitochondrial complex i, 10 kda subunit (11 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit a9 (43 kDa, Protein from Sheep)
- 1,4-dihydronicotinamide adenine dinucleotide (665 Da, Ligand)
- Mitochondrial complex i, 24 kda subunit (27 kDa, Protein from Sheep)
- Water (18 Da, Ligand)
- Mitochondrial complex i, b16.6 subunit (16 kDa, Protein from Sheep)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (19 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit a6 (16 kDa, Protein from Sheep)
- S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
Complex I during turnover, closed
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 6zkc
Q-score: 0.523
Science (2020) 370 [ Pubmed: 32972993 DOI: doi:10.1126/science.abc4209 ]
- Flavin mononucleotide (456 Da, Ligand)
- Potassium ion (39 Da, Ligand)
- Nadh:ubiquinone oxidoreductase subunit b4 (15 kDa, Protein from Sheep)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from Sheep)
- Mitochondrial complex i, mnll subunit (7 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit a3 (9 kDa, Protein from Sheep)
- Nadh-ubiquinone oxidoreductase chain 1 (35 kDa, Protein from Sheep)
- Nadh-ubiquinone oxidoreductase chain 4 (52 kDa, Protein from Sheep)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (50 kDa, Protein from Sheep)
- Iron/sulfur cluster (351 Da, Ligand)
- 1,2-diacyl-sn-glycero-3-phosphoethanolamine (748 Da, Ligand)
- Mitochondrial complex i, kfyi subunit (8 kDa, Protein from Sheep)
- Nadh-ubiquinone oxidoreductase chain 6 (19 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit b9 (21 kDa, Protein from Sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (11 kDa, Protein from Sheep)
- Mitochondrial complex i, 49 kda subunit (52 kDa, Protein from Sheep)
- Complex i during turnover, closed (1 MDa, Complex from Ovis aries)
- Nadh:ubiquinone oxidoreductase core subunit s3 (30 kDa, Protein from Sheep)
- Mitochondrial complex i, pdsw subunit (20 kDa, Protein from Sheep)
- Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from Sheep)
- Mitochondrial complex i, b14.7 subunit (14 kDa, Protein from Sheep)
- Mitochondrial complex i, psst subunit (24 kDa, Protein from Sheep)
- Mitochondrial complex i, mwfe subunit (8 kDa, Protein from Sheep)
- Nadh-ubiquinone oxidoreductase chain 3 (13 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase core subunit s1 (79 kDa, Protein from Sheep)
- Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from Sheep)
- Mitochondrial complex i, tyky subunit (24 kDa, Protein from Sheep)
- Adenosine monophosphate (347 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (20 kDa, Protein from Sheep)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Cardiolipin (1 kDa, Ligand)
- Nadh:ubiquinone oxidoreductase subunit b7 (16 kDa, Protein from Sheep)
- Mitochondrial complex i, b13 subunit (13 kDa, Protein from Sheep)
- Zinc ion (65 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (40 kDa, Protein from Sheep)
- Mitochondrial complex i, b17 subunit (15 kDa, Protein from Sheep)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Acyl carrier protein (17 kDa, Protein from Sheep)
- Mitochondrial complex i, 13 kda subunit (13 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit b3 (11 kDa, Protein from Sheep)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (21 kDa, Protein from Sheep)
- Mitochondrial complex i, b14.5a subunit (12 kDa, Protein from Sheep)
- Mitochondrial complex i, 10 kda subunit (11 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit a9 (43 kDa, Protein from Sheep)
- Myristic acid (228 Da, Ligand)
- 2-decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione (322 Da, Ligand)
- 1,4-dihydronicotinamide adenine dinucleotide (665 Da, Ligand)
- Mitochondrial complex i, 24 kda subunit (27 kDa, Protein from Sheep)
- Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from Sheep)
- Mitochondrial complex i, b16.6 subunit (16 kDa, Protein from Sheep)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (19 kDa, Protein from Sheep)
- Nadh-ubiquinone oxidoreductase chain 2 (39 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit s5 (12 kDa, Protein from Sheep)
- Mitochondrial complex i, esss subunit (17 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit a6 (16 kDa, Protein from Sheep)
- S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
- Nadh:ubiquinone oxidoreductase subunit b2 (12 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit b5 (21 kDa, Protein from Sheep)
Complex I during turnover, open1
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 6zkd
Q-score: 0.579
Science (2020) 370 [ Pubmed: 32972993 DOI: doi:10.1126/science.abc4209 ]
- Flavin mononucleotide (456 Da, Ligand)
- Potassium ion (39 Da, Ligand)
- Nadh:ubiquinone oxidoreductase subunit b4 (15 kDa, Protein from Sheep)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from Sheep)
- Mitochondrial complex i, mnll subunit (7 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit a3 (9 kDa, Protein from Sheep)
- Nadh-ubiquinone oxidoreductase chain 1 (35 kDa, Protein from Sheep)
- Nadh-ubiquinone oxidoreductase chain 4 (52 kDa, Protein from Sheep)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (50 kDa, Protein from Sheep)
- Iron/sulfur cluster (351 Da, Ligand)
- 1,2-diacyl-sn-glycero-3-phosphoethanolamine (748 Da, Ligand)
- Mitochondrial complex i, kfyi subunit (8 kDa, Protein from Sheep)
- Nadh-ubiquinone oxidoreductase chain 6 (19 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit b9 (21 kDa, Protein from Sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (11 kDa, Protein from Sheep)
- Mitochondrial complex i, 49 kda subunit (52 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase core subunit s3 (30 kDa, Protein from Sheep)
- Mitochondrial complex i, pdsw subunit (20 kDa, Protein from Sheep)
- Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from Sheep)
- Mitochondrial complex i, b14.7 subunit (14 kDa, Protein from Sheep)
- Complex i during turnover, open1 (1 MDa, Complex from Ovis aries)
- Mitochondrial complex i, psst subunit (24 kDa, Protein from Sheep)
- Mitochondrial complex i, mwfe subunit (8 kDa, Protein from Sheep)
- Nadh-ubiquinone oxidoreductase chain 3 (13 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase core subunit s1 (79 kDa, Protein from Sheep)
- Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from Sheep)
- Mitochondrial complex i, tyky subunit (24 kDa, Protein from Sheep)
- Adenosine monophosphate (347 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (20 kDa, Protein from Sheep)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Cardiolipin (1 kDa, Ligand)
- Nadh:ubiquinone oxidoreductase subunit b7 (16 kDa, Protein from Sheep)
- Mitochondrial complex i, b13 subunit (13 kDa, Protein from Sheep)
- Zinc ion (65 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (40 kDa, Protein from Sheep)
- Mitochondrial complex i, b17 subunit (15 kDa, Protein from Sheep)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Acyl carrier protein (17 kDa, Protein from Sheep)
- Mitochondrial complex i, 13 kda subunit (13 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit b3 (11 kDa, Protein from Sheep)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (21 kDa, Protein from Sheep)
- Mitochondrial complex i, b14.5a subunit (12 kDa, Protein from Sheep)
- Mitochondrial complex i, 10 kda subunit (11 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit a9 (43 kDa, Protein from Sheep)
- Myristic acid (228 Da, Ligand)
- 2-decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione (322 Da, Ligand)
- 1,4-dihydronicotinamide adenine dinucleotide (665 Da, Ligand)
- Mitochondrial complex i, 24 kda subunit (27 kDa, Protein from Sheep)
- Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from Sheep)
- Mitochondrial complex i, b16.6 subunit (16 kDa, Protein from Sheep)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (19 kDa, Protein from Sheep)
- Nadh-ubiquinone oxidoreductase chain 2 (39 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit s5 (12 kDa, Protein from Sheep)
- Mitochondrial complex i, esss subunit (17 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit a6 (16 kDa, Protein from Sheep)
- S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
- Nadh:ubiquinone oxidoreductase subunit b2 (12 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit b5 (21 kDa, Protein from Sheep)
Complex I during turnover, open2
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 6zke
Q-score: 0.598
Science (2020) 370 [ Pubmed: 32972993 DOI: doi:10.1126/science.abc4209 ]
- Flavin mononucleotide (456 Da, Ligand)
- Potassium ion (39 Da, Ligand)
- Nadh:ubiquinone oxidoreductase subunit b4 (15 kDa, Protein from Sheep)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from Sheep)
- Mitochondrial complex i, mnll subunit (7 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit a3 (9 kDa, Protein from Sheep)
- Nadh-ubiquinone oxidoreductase chain 1 (35 kDa, Protein from Sheep)
- Nadh-ubiquinone oxidoreductase chain 4 (52 kDa, Protein from Sheep)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (50 kDa, Protein from Sheep)
- Iron/sulfur cluster (351 Da, Ligand)
- 1,2-diacyl-sn-glycero-3-phosphoethanolamine (748 Da, Ligand)
- Mitochondrial complex i, kfyi subunit (8 kDa, Protein from Sheep)
- Nadh-ubiquinone oxidoreductase chain 6 (19 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit b9 (21 kDa, Protein from Sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (11 kDa, Protein from Sheep)
- Mitochondrial complex i, 49 kda subunit (52 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase core subunit s3 (30 kDa, Protein from Sheep)
- Mitochondrial complex i, pdsw subunit (20 kDa, Protein from Sheep)
- Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from Sheep)
- Mitochondrial complex i, b14.7 subunit (14 kDa, Protein from Sheep)
- Mitochondrial complex i, psst subunit (24 kDa, Protein from Sheep)
- Mitochondrial complex i, mwfe subunit (8 kDa, Protein from Sheep)
- Nadh-ubiquinone oxidoreductase chain 3 (13 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase core subunit s1 (79 kDa, Protein from Sheep)
- Complex i during turnover, open2 (1 MDa, Complex from Ovis aries)
- Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from Sheep)
- Mitochondrial complex i, tyky subunit (24 kDa, Protein from Sheep)
- Adenosine monophosphate (347 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (20 kDa, Protein from Sheep)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Cardiolipin (1 kDa, Ligand)
- Nadh:ubiquinone oxidoreductase subunit b7 (16 kDa, Protein from Sheep)
- Mitochondrial complex i, b13 subunit (13 kDa, Protein from Sheep)
- Zinc ion (65 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (40 kDa, Protein from Sheep)
- Mitochondrial complex i, b17 subunit (15 kDa, Protein from Sheep)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Acyl carrier protein (17 kDa, Protein from Sheep)
- Mitochondrial complex i, 13 kda subunit (13 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit b3 (11 kDa, Protein from Sheep)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (21 kDa, Protein from Sheep)
- Mitochondrial complex i, b14.5a subunit (12 kDa, Protein from Sheep)
- Mitochondrial complex i, 10 kda subunit (11 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit a9 (43 kDa, Protein from Sheep)
- Myristic acid (228 Da, Ligand)
- 2-decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione (322 Da, Ligand)
- 1,4-dihydronicotinamide adenine dinucleotide (665 Da, Ligand)
- Mitochondrial complex i, 24 kda subunit (27 kDa, Protein from Sheep)
- Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from Sheep)
- Mitochondrial complex i, b16.6 subunit (16 kDa, Protein from Sheep)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (19 kDa, Protein from Sheep)
- Nadh-ubiquinone oxidoreductase chain 2 (39 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit s5 (12 kDa, Protein from Sheep)
- Mitochondrial complex i, esss subunit (17 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit a6 (16 kDa, Protein from Sheep)
- S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
- Nadh:ubiquinone oxidoreductase subunit b2 (12 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit b5 (21 kDa, Protein from Sheep)
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 6zkg
Q-score: 0.48
Science (2020) 370 [ Pubmed: 32972993 DOI: doi:10.1126/science.abc4209 ]
- Flavin mononucleotide (456 Da, Ligand)
- Potassium ion (39 Da, Ligand)
- Nadh:ubiquinone oxidoreductase subunit b4 (15 kDa, Protein from Sheep)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from Sheep)
- Mitochondrial complex i, mnll subunit (7 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit a3 (9 kDa, Protein from Sheep)
- Nadh-ubiquinone oxidoreductase chain 1 (35 kDa, Protein from Sheep)
- Nadh-ubiquinone oxidoreductase chain 4 (52 kDa, Protein from Sheep)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (50 kDa, Protein from Sheep)
- Iron/sulfur cluster (351 Da, Ligand)
- 1,2-diacyl-sn-glycero-3-phosphoethanolamine (748 Da, Ligand)
- Complex i with nadh, closed (1 MDa, Complex from Ovis aries)
- Mitochondrial complex i, kfyi subunit (8 kDa, Protein from Sheep)
- Nadh-ubiquinone oxidoreductase chain 6 (19 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit b9 (21 kDa, Protein from Sheep)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (11 kDa, Protein from Sheep)
- Mitochondrial complex i, 49 kda subunit (52 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase core subunit s3 (30 kDa, Protein from Sheep)
- Mitochondrial complex i, pdsw subunit (20 kDa, Protein from Sheep)
- Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from Sheep)
- Mitochondrial complex i, b14.7 subunit (14 kDa, Protein from Sheep)
- Mitochondrial complex i, psst subunit (24 kDa, Protein from Sheep)
- Mitochondrial complex i, mwfe subunit (8 kDa, Protein from Sheep)
- Nadh-ubiquinone oxidoreductase chain 3 (13 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase core subunit s1 (79 kDa, Protein from Sheep)
- Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from Sheep)
- Mitochondrial complex i, tyky subunit (24 kDa, Protein from Sheep)
- Adenosine monophosphate (347 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (20 kDa, Protein from Sheep)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Cardiolipin (1 kDa, Ligand)
- Nadh:ubiquinone oxidoreductase subunit b7 (16 kDa, Protein from Sheep)
- Mitochondrial complex i, b13 subunit (13 kDa, Protein from Sheep)
- Zinc ion (65 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (40 kDa, Protein from Sheep)
- Mitochondrial complex i, b17 subunit (15 kDa, Protein from Sheep)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Acyl carrier protein (17 kDa, Protein from Sheep)
- Mitochondrial complex i, 13 kda subunit (13 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit b3 (11 kDa, Protein from Sheep)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (21 kDa, Protein from Sheep)
- Mitochondrial complex i, b14.5a subunit (12 kDa, Protein from Sheep)
- Mitochondrial complex i, 10 kda subunit (11 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit a9 (43 kDa, Protein from Sheep)
- Myristic acid (228 Da, Ligand)
- 1,4-dihydronicotinamide adenine dinucleotide (665 Da, Ligand)
- Mitochondrial complex i, 24 kda subunit (27 kDa, Protein from Sheep)
- Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from Sheep)
- Mitochondrial complex i, b16.6 subunit (16 kDa, Protein from Sheep)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (19 kDa, Protein from Sheep)
- Nadh-ubiquinone oxidoreductase chain 2 (39 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit s5 (12 kDa, Protein from Sheep)
- Mitochondrial complex i, esss subunit (17 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit a6 (16 kDa, Protein from Sheep)
- S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
- Nadh:ubiquinone oxidoreductase subunit b2 (12 kDa, Protein from Sheep)
- Nadh:ubiquinone oxidoreductase subunit b5 (21 kDa, Protein from Sheep)