HIV-1 BG505 Env SOSIP in complex with bovine Fab Bess4 and non-human primate Fab RM20A3
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 8tq1
Q-score: 0.512
Altman PX, Ozorowski G, Stanfield RL, Haakenson J, Appel M, Parren M, Lee WH, Sang H, Woehl J, Saye-Francisco K, Sewall LM, Joyce C, Song G, Porter K, Landais E, Andrabi R, Wilson IA, Ward AB, Mwangi W, Smider VV, Burton DR, Sok D
PLoS Pathog (2024) 20 pp. e1012042-e1012042 [ DOI: doi:10.1371/journal.ppat.1012042 Pubmed: 39250525 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Nhp rm20a3 fab heavy chain (13 kDa, Protein from Macaca mulatta)
- Bovine bess4 fab heavy chain (17 kDa, Protein from Bos taurus)
- Transmembrane protein gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- Hiv-1 envelope glycoprotein bg505 sosip.664 gp120 (57 kDa, Protein from Human immunodeficiency virus 1)
- Nhp rm20a3 fab light chain (13 kDa, Protein from Macaca mulatta)
- Hiv-1 bg505 sosip env in complex with bovine bess4 fab and nhp rm20a3 fab (Complex from Human immunodeficiency virus 1)
Cryo-EM structure of llama J3 VHH antibody in complex with HIV-1 Env BG505 DS-SOSIP.664
Resolution: 3.61 Å
EM Method: Single-particle
Fitted PDBs: 7lpn
Q-score: 0.465
Zhou T, Chen L, Gorman J, Wang S, Kwon YD, Lin BC, Louder MK, Rawi R, Stancofski ED, Yang Y, Zhang B, Quigley AF, McCoy LE, Rutten L, Verrips T, Weiss RA, Doria-Rose NA, Shapiro L, Kwong PD
Structure (2022) 30 pp. 862-875.e4 [ Pubmed: 35413243 DOI: doi:10.1016/j.str.2022.03.012 ]
- Hiv-1 env with llama j3 vhh (Complex from Human immunodeficiency virus 1)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- J3 vhh (14 kDa, Protein from Lama glama)
- Hiv-1 envelope glycoprotein bg505 sosip.664 gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- Envelope glycoprotein gp160 (53 kDa, Protein from Human immunodeficiency virus 1)
Cryo-EM structure of M4008_N1 Fab in complex with BG505 DS-SOSIP.664 Env trimer
Resolution: 3.24 Å
EM Method: Single-particle
Fitted PDBs: 7rai
Q-score: 0.529
Chan KW, Luo CC, Lu H, Wu X, Kong XP
Nat Commun (2021) 12 pp. 6464-6464 [ Pubmed: 34753944 DOI: doi:10.1038/s41467-021-26846-z ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- M4008_n1 fab heavy chain (28 kDa, Protein from Homo sapiens)
- Hiv-1 envelope glycoprotein bg505 sosip.664 gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- M4008_n1 fab in complex with bg505 ds-sosip.664 env trimer (Complex from Homo sapiens)
- Envelope glycoprotein gp160 (53 kDa, Protein from Human immunodeficiency virus 1)
- M4008_n1 fab light chain (23 kDa, Protein from Homo sapiens)
Cryo-EM structure of SHIV-elicited RHA1.V2.01 in complex with HIV-1 Env BG505 DS-SOSIP.664
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 6xrt
Q-score: 0.322
Roark RS, Li H, Williams WB, Chug H, Mason RD, Gorman J, Wang S, Lee FH, Rando J, Bonsignori M, Hwang KK, Saunders KO, Wiehe K, Moody MA, Hraber PT, Wagh K, Giorgi EE, Russell RM, Bibollet-Ruche F, Liu W, Connell J, Smith AG, DeVoto J, Murphy AI, Smith J, Ding W, Zhao C, Chohan N, Okumura M, Rosario C, Ding Y, Lindemuth E, Bauer AM, Bar KJ, Ambrozak D, Chao CW, Chuang GY, Geng H, Lin BC, Louder MK, Nguyen R, Zhang B, Lewis MG, Raymond DD, Doria-Rose NA, Schramm CA, Douek DC, Roederer M, Kepler TB, Kelsoe G, Mascola JR, Kwong PD, Korber BT, Harrison SC, Haynes BF, Hahn BH, Shaw GM
Science (2021) 371 [ Pubmed: 33214287 DOI: doi:10.1126/science.abd2638 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Cryo-em structure of shiv-elicited rha1.v2.01 in complex with hiv-1 env bg505 ds-sosip (Complex)
- Cryo-em structure of shiv-elicited rha1.v2.01 in complex with hiv-1 env bg505 ds-sosip.664 (Complex from Human immunodeficiency virus 1)
- Hiv-1 envelope glycoprotein bg505 sosip.664 gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- Vrc01.23 light chain (11 kDa, Protein from Macaca mulatta)
- Vrc01.23 heavy chain (14 kDa, Protein from Macaca mulatta)
- Envelope glycoprotein gp160 (53 kDa, Protein from Human immunodeficiency virus 1)