The cryo-EM structure of the yeast RAD51 filament bound to ssDNA in the presence of ATP
To Be Published
- Rad51 filament - ssdna (Complex from Saccharomyces cerevisiae)
- Magnesium ion (24 Da, Ligand)
- Dna (5'-d(p*tp*tp*tp*tp*tp*tp*tp*tp*tp*tp*tp*tp*tp*tp*tp*tp*tp*t)-3') (5 kDa, DNA from Saccharomyces cerevisiae)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Dna repair protein rad51 (34 kDa, Protein from Saccharomyces cerevisiae)
Sulfolobus acidocaldarius AAP filament
Resolution: 2.6 Å
EM Method: Helical reconstruction
Fitted PDBs: 9ets
Q-score: 0.517
Gaines MC, Isupov MN, McLaren M, Mollat CL, Haque RU, Stephenson JK, Sivabalasarma S, Hanus C, Kattnig D, Gold VAM, Albers S, Daum B
Nat Commun (2024) 15 pp. 10401-10401 [ DOI: doi:10.1038/s41467-024-53986-9 Pubmed: 39614099 ]
Structure of the AAP filament of Sulfolobus acidocaldarius strain MW039 (delta agl3 mutant).
Resolution: 2.38 Å
EM Method: Helical reconstruction
Fitted PDBs: 9ev0
Q-score: 0.556
Gaines MC, Isupov MN, McLaren M, Mollat CL, Haque RU, Stephenson JK, Sivabalasarma S, Hanus C, Kattnig D, Gold VAM, Albers S, Daum B
Nat Commun (2024) 15 pp. 10401-10401 [ Pubmed: 39614099 DOI: doi:10.1038/s41467-024-53986-9 ]
Broad substrate scope C-C oxidation in cyclodipeptides catalysed by a flavin-dependent filament
Resolution: 3.0 Å
EM Method: Helical reconstruction
Fitted PDBs: 9exv
Q-score: 0.411
Sutherland E, Harding CJ, du Monceau de Bergendal T, Florence GJ, Ackermann K, Bode BE, Synowsky S, Sundaramoorthy R, Czekster CM
Nat Commun (2025) 16 pp. 995-995 [ DOI: doi:10.1038/s41467-025-56127-y Pubmed: 39856061 ]
- Nitroreductase (21 kDa, Protein from Nocardiopsis dassonvillei)
- Flavin mononucleotide (456 Da, Ligand)
- Albb (11 kDa, Protein from Nocardiopsis dassonvillei)
- Filament of nocardiopsis dassonvillei cyclodipeptide enzyme (330 kDa, Complex from Nocardiopsis dassonvillei)
Human liver phosphofructokinase-1 filament in the R-state conformation
Lynch EM, Hansen H, Salay L, Cooper M, Timr S, Kollman JM, Webb BA
Nat Commun (2024) 15 pp. 7323-7323 [ DOI: doi:10.1038/s41467-024-51808-6 Pubmed: 39183237 ]
- 1,6-di-o-phosphono-beta-d-fructofuranose (340 Da, Ligand)
- Pfkl filament (Complex from Homo sapiens)
- 6-o-phosphono-beta-d-fructofuranose (260 Da, Ligand)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Atp-dependent 6-phosphofructokinase, liver type (85 kDa, Protein from Homo sapiens)
To Be Published
- Rat skeletal muscle filament actin (Cellular component from Rattus norvegicus)
- Actin, alpha skeletal muscle (41 kDa, Protein from Rattus norvegicus)
- Adenosine-5'-diphosphate (427 Da, Ligand)
The cryo-EM structure of the yeast Dmc1 filament bound to ssDNA in the presence of ATP
To Be Published
- Cryo-em structure of yeast dmc1 filament bound on ssdna in the presence of atp (Complex from Saccharomyces cerevisiae)
- Magnesium ion (24 Da, Ligand)
- Dna (5'-d(p*tp*tp*tp*tp*tp*tp*tp*tp*tp*tp*tp*tp*tp*tp*tp*tp*tp*t)-3') (5 kDa, DNA from Saccharomyces cerevisiae)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Meiotic recombination protein dmc1 (36 kDa, Protein from Saccharomyces cerevisiae)
TRIF TIR Filament Cryo-EM Structure
Resolution: 3.3 Å
EM Method: Helical reconstruction
Fitted PDBs: 9dk8
Q-score: 0.47
Cryo-EM structure of yeast Rad51 nucleoprotein filament bound to Rad54peptide
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 9e6l
Q-score: 0.459
To Be Published
- Dna (5'-d(p*tp*tp*tp*tp*tp*tp*tp*tp*tp*tp*tp*tp*tp*tp*tp*tp*tp*t)-3') (5 kDa, DNA from Saccharomyces cerevisiae)
- Rad51 nucleoprotein filament bound to rad54 peptide (Complex from Saccharomyces cerevisiae)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Dna repair and recombination protein rad54 (4 kDa, Protein from Saccharomyces cerevisiae)
- Dna repair protein rad51 (34 kDa, Protein from Saccharomyces cerevisiae)
Cryo-EM structure of yeast Rad51 nucleoprotein filament bound to Hed1
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 9e6n
Q-score: 0.508
To Be Published
- Dna (5'-d(p*tp*tp*tp*tp*tp*tp*tp*tp*tp*tp*tp*tp*tp*tp*tp*tp*tp*t)-3') (5 kDa, DNA from Saccharomyces cerevisiae)
- Meiosis-specific protein hed1 (3 kDa, Protein from Saccharomyces cerevisiae)
- Yeast rad51 nucleoprotein filament bound to hed1peptide (Complex from Saccharomyces cerevisiae)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Dna repair protein rad51 (34 kDa, Protein from Saccharomyces cerevisiae)