Paired helical tau filaments in dominantly inherited Alzheimer disease with cotton wool plaques
Resolution: 3.0 Å
EM Method: Helical reconstruction
Fitted PDBs: 9czi
Q-score: 0.588
Hoq MR, Fernandez A, Vago FS, Hallinan GI, Bharath SR, Li D, Ozcan KA, Garringer HJ, Jiang W, Vidal R, Ghetti B
Acta Neuropathol (2024) 148 pp. 20-20 [ Pubmed: 39147931 DOI: doi:10.1007/s00401-024-02786-y ]
- Microtubule-associated protein tau (7 kDa, Protein from Homo sapiens)
- Paired helical tau filament (Tissue from Homo sapiens)
Straight tau filaments in dominantly inherited Alzheimer disease with cotton wool plaques
Resolution: 2.9 Å
EM Method: Helical reconstruction
Fitted PDBs: 9czl
Q-score: 0.571
Hoq MR, Fernandez A, Vago FS, Hallinan GI, Bharath SR, Li D, Ozcan KA, Garringer HJ, Jiang W, Vidal R, Ghetti B
Acta Neuropathol (2024) 148 pp. 20-20 [ Pubmed: 39147931 DOI: doi:10.1007/s00401-024-02786-y ]
Type IIIa beta-amyloid 40 Filaments from Down syndrome
Resolution: 3.5 Å
EM Method: Helical reconstruction
Fitted PDBs: 8sek
Q-score: 0.481
Fernandez A, Hoq MR, Hallinan GI, Li D, Bharath SR, Vago FS, Zhang X, Ozcan KA, Newell KL, Garringer HJ, Jiang W, Ghetti B, Vidal R
Nat Struct Mol Biol (2024) 31 pp. 903-909 [ DOI: doi:10.1038/s41594-024-01252-3 Pubmed: 38553642 ]
- Type iiib beta-amyloid 40 filament (4 kDa, Protein from Homo sapiens)
- Type iiia beta amyloid 40 (Tissue from Homo sapiens)
Structure of Type I Prion filaments from Gerstmann-Straussler-Scheinker disease
Resolution: 3.29 Å
EM Method: Helical reconstruction
Fitted PDBs: 7umq
Q-score: 0.481
Hallinan GI, Ozcan KA, Hoq MR, Cracco L, Vago FS, Bharath SR, Li D, Jacobsen M, Doud EH, Mosley AL, Fernandez A, Garringer HJ, Jiang W, Ghetti B, Vidal R
Acta Neuropathol (2022) 144 pp. 509-520 [ Pubmed: 35819518 DOI: doi:10.1007/s00401-022-02461-0 ]
Structure of Type II Prion filaments from Gerstmann-Straussler-Scheinker disease
Resolution: 3.13 Å
EM Method: Helical reconstruction
Fitted PDBs: 7un5
Q-score: 0.544
Hallinan GI, Ozcan KA, Hoq MR, Cracco L, Vago FS, Bharath SR, Li D, Jacobsen M, Doud EH, Mosley AL, Fernandez A, Garringer HJ, Jiang W, Ghetti B, Vidal R
Acta Neuropathol (2022) 144 pp. 509-520 [ Pubmed: 35819518 DOI: doi:10.1007/s00401-022-02461-0 ]
Straight tau filament extracted from PrP-CAA Patient brain tissue | tau filament | SF Tau
Resolution: 3.07 Å
EM Method: Helical reconstruction
Fitted PDBs: 7mkg
Q-score: 0.406
Hallinan GI, Hoq MR, Ghosh M, Vago FS, Fernandez A, Garringer HJ, Vidal R, Jiang W, Ghetti B
Acta Neuropathol (2021) 142 pp. 227-241 [ Pubmed: 34128081 DOI: doi:10.1007/s00401-021-02336-w ]
Resolution: 3.3 Å
EM Method: Helical reconstruction
Fitted PDBs: 7mkh
Q-score: 0.403
Hallinan GI, Hoq MR, Ghosh M, Vago FS, Fernandez A, Garringer HJ, Vidal R, Jiang W, Ghetti B
Acta Neuropathol (2021) 142 pp. 227-241 [ Pubmed: 34128081 DOI: doi:10.1007/s00401-021-02336-w ]
Paired helical tau filament extracted from PrP-CAA Patient brain tissue | tau filament | PHF Tau
Resolution: 3.0 Å
EM Method: Helical reconstruction
Fitted PDBs: 7mkf
Q-score: 0.423
Hallinan GI, Hoq MR, Ghosh M, Vago FS, Fernandez A, Garringer HJ, Vidal R, Jiang W, Ghetti B
Acta Neuropathol (2021) 142 pp. 227-241 [ Pubmed: 34128081 DOI: doi:10.1007/s00401-021-02336-w ]