PHF type tau filament from V337M mutant
Resolution: 2.8 Å
EM Method: Helical reconstruction
Fitted PDBs: 9eo7
Q-score: 0.568
Qi C, Lovestam S, Murzin AG, Peak-Chew S, Franco C, Bogdani M, Latimer C, Murrell JR, Cullinane PW, Jaunmuktane Z, Bird TD, Ghetti B, Scheres SHW, Goedert M
bioRxiv (2024) [ Pubmed: 38746388 DOI: doi:10.1101/2024.04.29.591661 ]
- Tau filament v337m (Complex from Homo sapiens)
- Isoform tau-f of microtubule-associated protein tau (45 kDa, Protein from Homo sapiens)
PHF type tau filament from V337M mutant
Resolution: 3.3 Å
EM Method: Helical reconstruction
Fitted PDBs: 9eo9
Q-score: 0.486
Qi C, Lovestam S, Murzin AG, Peak-Chew S, Franco C, Bogdani M, Latimer C, Murrell JR, Cullinane PW, Jaunmuktane Z, Bird TD, Ghetti B, Scheres SHW, Goedert M
bioRxiv (2024) [ Pubmed: 38746388 DOI: doi:10.1101/2024.04.29.591661 ]
PHF type tau filament from V337M mutant
Resolution: 2.3 Å
EM Method: Helical reconstruction
Fitted PDBs: 9eoe
Q-score: 0.641
Qi C, Lovestam S, Murzin AG, Peak-Chew S, Franco C, Bogdani M, Latimer C, Murrell JR, Cullinane PW, Jaunmuktane Z, Bird TD, Ghetti B, Scheres SHW, Goedert M
bioRxiv (2024) [ Pubmed: 38746388 DOI: doi:10.1101/2024.04.29.591661 ]
PHF type tau filament from R406W mutant
Resolution: 3.0 Å
EM Method: Helical reconstruction
Fitted PDBs: 9eog
Q-score: 0.573
Qi C, Lovestam S, Murzin AG, Peak-Chew S, Franco C, Bogdani M, Latimer C, Murrell JR, Cullinane PW, Jaunmuktane Z, Bird TD, Ghetti B, Scheres SHW, Goedert M
bioRxiv (2024) [ Pubmed: 38746388 DOI: doi:10.1101/2024.04.29.591661 ]
- Microtubule-associated protein tau (45 kDa, Protein from Homo sapiens)
- Phf tau filament from mutant r406w (Complex from Homo sapiens)
PHF type tau filament from in vitro V337M mutant
Resolution: 2.8 Å
EM Method: Helical reconstruction
Fitted PDBs: 9eoh
Q-score: 0.572
Qi C, Lovestam S, Murzin AG, Peak-Chew S, Franco C, Bogdani M, Latimer C, Murrell JR, Cullinane PW, Jaunmuktane Z, Bird TD, Ghetti B, Scheres SHW, Goedert M
bioRxiv (2024) [ Pubmed: 38746388 DOI: doi:10.1101/2024.04.29.591661 ]
Resolution: 3.47 Å
EM Method: Helical reconstruction
Fitted PDBs: 7nca
Q-score: 0.559
Lovestam S, Schweighauser M, Matsubara T, Murayama S, Tomita T, Ando T, Hasegawa K, Yoshida M, Tarutani A, Hasegawa M, Goedert M, Scheres SHW
FEBS Open Bio (2021) 11 pp. 999-1013 [ DOI: doi:10.1002/2211-5463.13110 Pubmed: 33548114 ]
- Alpha-synuclein (14 kDa, Protein from Homo sapiens)
- Alpha synuclein filament (Complex from Homo sapiens)
Resolution: 3.43 Å
EM Method: Helical reconstruction
Fitted PDBs: 7ncg
Q-score: 0.494
Lovestam S, Schweighauser M, Matsubara T, Murayama S, Tomita T, Ando T, Hasegawa K, Yoshida M, Tarutani A, Hasegawa M, Goedert M, Scheres SHW
FEBS Open Bio (2021) 11 pp. 999-1013 [ DOI: doi:10.1002/2211-5463.13110 Pubmed: 33548114 ]
- Alpha-synuclein (14 kDa, Protein from Homo sapiens)
- Alpha synuclein filament (Complex from Homo sapiens)
Resolution: 3.84 Å
EM Method: Helical reconstruction
Fitted PDBs: 7nch
Q-score: 0.244
Lovestam S, Schweighauser M, Matsubara T, Murayama S, Tomita T, Ando T, Hasegawa K, Yoshida M, Tarutani A, Hasegawa M, Goedert M, Scheres SHW
FEBS Open Bio (2021) 11 pp. 999-1013 [ DOI: doi:10.1002/2211-5463.13110 Pubmed: 33548114 ]
- Alpha-synuclein (14 kDa, Protein from Homo sapiens)
- Alpha synuclein filament (Complex from Homo sapiens)
Resolution: 3.55 Å
EM Method: Helical reconstruction
Fitted PDBs: 7nci
Q-score: 0.377
Lovestam S, Schweighauser M, Matsubara T, Murayama S, Tomita T, Ando T, Hasegawa K, Yoshida M, Tarutani A, Hasegawa M, Goedert M, Scheres SHW
FEBS Open Bio (2021) 11 pp. 999-1013 [ DOI: doi:10.1002/2211-5463.13110 Pubmed: 33548114 ]
- Alpha-synuclein (14 kDa, Protein from Homo sapiens)
- Alpha synuclein filament (Complex from Homo sapiens)
Resolution: 4.23 Å
EM Method: Helical reconstruction
Fitted PDBs: 7ncj
Q-score: 0.176
Lovestam S, Schweighauser M, Matsubara T, Murayama S, Tomita T, Ando T, Hasegawa K, Yoshida M, Tarutani A, Hasegawa M, Goedert M, Scheres SHW
FEBS Open Bio (2021) 11 pp. 999-1013 [ DOI: doi:10.1002/2211-5463.13110 Pubmed: 33548114 ]
- Alpha-synuclein (14 kDa, Protein from Homo sapiens)
- Alpha synuclein filament (Complex from Homo sapiens)